SYNTHETICS and COMPOUNDS THAT AFFECT the ECS 2010-2020
(Derivatives are usually classed with their parent compound simply
because they are coming out so fast and may vanish just as fast)
KM-233 (CB2 Agonist)
KML-29 (Stops Production of MAGL, Preventing Breakdown of 2-AG)
KN38-7271/BAY38-7271 (CB1 and CB2 Agonist)
LBP-1 (CB1 Agonist with a Minimal High)
LEI-105 (Potent, Highly Selective, Revers
ible Dual DAGL-α/DAGL-β Inhibitor)
LH–21 (Low-Permeant Neutral CB1 Antagonist)
LV-50 (Strong CB2 Agonist)
LY21813240 (CB1 Agonist)
LY2828360 (CB2 Agonist)
LY3038404 HCl (Highly Selective CB2 Agonist)
MAB-CHMINACA/ADB-CHMINACA
MAM-2201 (CB1 and CB2 Agonist, Hybrid of JWH-122 and AM-2201)
MARINOL/DRONABINOL* (Synthetic THC, CB1 and CB2 Agonist)
MDA-7 (Strong CB2 Agonist)
MDA-19 (Strong CB2 Agonist)
MDMB-CHMCZA
MJN-110 (Blocks Breakdown of 2-AG)
MK-0364 (See TARANABANT)
ML-184 (GPR-55 Antagonist)
ML-193 (GPR-55 Antagonist)
MM-433593 (Inhibits FAAH Thus Increasing Anandamide)
MRI-1867 (Peripherally Restricted Hybrid CB R/iNOS Inhibitor 1)
MT-178 (CB2 Agonist)
NABILONE/CESAMET (Synthetic THC, CB1 and CB2 Agonist)
NESS0327 (CB1 Antagonist)
NESS06SM (CB2 Antagonist)
NIDA-41020 (Powerful CB1 Antagonist)
NM2201/BLACK MAMBA
NMP-7 (CB2 Agonist)
NMP-181 (CB2 Agonist)
NST/NS TYR/N-STEAROYL-1-TYROSINE (Anandamide Analog)
O-1602 (Cannabidiol Analog, GPR18 and GPR55 Agonist)
O-1663 (Acts Like Combination of THC and CBD)
O-1918 (GPR18 Antagonist)
O-1966 (CB2 Agonist)
O-2050 (CB1 Antagonist)
O-2545 (CB1 Agonist)
O-7460 (Blocks Formation of 2-AG)
OCTADECYLPROPYL SULFAMIDE (Synthetic Form of OEA)
OL-135 (FAAH Inhibitor)
OLIVE OIL (Omega -9 Source, May Cause Temporary Upregulation of CB1 Tumor Suppressor Gene and CB2 Receptors)
OMDM-1 (Blocks Re-uptake of Endocannabinoids)
OMDM-2 (Blocks Re-uptake of Endocannabinoids)
OMDM-188 (Diacylglycerol Lipase [DAGL] Enzyme Inhibitor)
ORG-27569 (Enhances Agonist-Binding Affinity to CB1)
PB-22/QUPIC/ ‘CRAZY MONKEY’/’PSYCLONE’ and DERIVATIVES
PF-622 (FAAH Inhibitor)
PF-3845 (Blocks Breakdown of Anandamide)
PF-04457845 (Blocks Breakdown of Anandamide)
PGN-33 (CB2 Agonist and Butyrylcholinesterase Inhibitor)
1-PHENYLISATIN (Selective CB2 Modulator)
PHTHALATES (Compounds in Plastic that Disrupt the Endocannabinoid System and Sex Hormone Levels)
PINACA GROUP
4(PM49) (CB1 Partial Agonist)
43(PM226) (Potent CB2 Agonist)
PnPP-19 (Synthetic Peptide, CB1 Agonist, Design Based on Spider Venom)
PrNMI (Peripherally Restricted CB1R Agonist)
PSN-632408 (GPR 119 Agonist)
QUPIC (See PB-22)
RCS-4
R-FLURBIPROFEN (May Help Restore More Normal Endocannabinoid Levels)
RHC-80267
RID-B (Tamoxifen Derivative, Selective CB2 Inverse Agonist)
RIMONABANT/ACOMPLIA/SR141716/SR1 (CB1 and CB2 Antagonist, GPR-55 Agonist, Failed Obesity Drug)
R(+)-METHANANANDAMIDE/AM-356 (More Stable Anandamide Analog)
Ro 61-8048 (Blocks THC “High”)
RQ-00202730 (Strong CB2 Agonist)
RX-055 (Blocks Uptake of Anandamide and 2-AG)
S-444823 (CB1 and CB2 Agonist)
S-777469 (CB2 Agonist)
SA-57 (Dual FAAH-MAGL Inhibitor)
SAB-378 (Activates Peripheral CB1 and CB2 Receptors, No “High”)
SAD-448 (Activates Peripheral CB1 Receptors, No “High”)
SAR-127303 (Prevents Breakdown of 2-AG)
SBFI26 (Fatty Acid-Binding Protein Inhibitor)
SER-601 (CB2 Agonist)
SGT-24/cumyl-PINACA
SLV-319 (See IBIPINABANT)
SMM–189 (CB2 Inverse Agonist)
SMM-295 (CB2 Agonist)
“SPICE”/“SCRAs” (Various Synthetic Cannabinoid Mixtures, See Also AM, HU, JWH and CP series)
SR-144528 (CB2 Receptor Antagonist)
SSR411298 (FAAH Inhibitor)
ST-4070 (FAAH Inhibitor)
SUGAR/FRUCTOSE
SUGAR/GLUCOSE
SUGAR/SUCROSE (Table Sugar)
SURINABANT/SR 147778 (CB1 Antagonist)
SYNDROS (Oral Liquid Formulation of Dronabinol; Synthetic THC Dissolved in Alcohol)
SYNTHETIC CBD
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KM-233
Synthesis of Novel Cannabinoid Ligands and Their Use as Anti-Glioma and Anti-Inflammatory Agents (full–2010) http://etd.uthsc.edu/WORLD-ACCESS/Gurley/2010-030-Gurley.pdf
Mechanism of anti-glioma activity and in vivo efficacy of the cannabinoid ligand KM-233 (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22875710
Functional selectivity of CB2 cannabinoid receptor ligands at a canonical and non- canonical pathway. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959096/
KML-29
Antinociceptive activity without cannabimimetic side effects. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954480/
Comparative biochemical characterization of the monoacylglycerol lipase inhibitor KML29 in brain, spinal cord, liver, spleen, fat and muscle tissue. (abst – 2014) https://www.sciencedirect.com/science/article/pii/S0028390814004456
Postnatal ethanol exposure alters levels of 2-arachidonylglycerol-metabolizing enzymes and pharmacological inhibition of monoacylglycerol (MAGL) does not cause neurodegeneration in neonatal mice. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490952/
Harnessing the Endocannabinoid 2-Arachidonoylglycerol to Lower Intraocular Pressure in a Murine Model. (USA/ Taiwan) (full – 2016) http://iovs.arvojournals.org/article.aspx?articleid=2530714
Emotional arousal state influences the ability of amygdalar endocannabinoid signaling to modulate anxiety. (Canada/ Italy) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0028390816303550
The monoacylglycerol lipase inhibitor KML29 with gabapentin synergistically produces analgesia in mice (USA) (full–2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715597/
Evaluation of monoacylglycerol lipase as a therapeutic target in a transgenic mouse model of ALS (Germany) (abst–2017) http://www.sciencedirect.com/science/article/pii/S0028390817301296?via%3Dihub
https://www.semanticscholar.org/paper/Evaluation-of-monoacylglycerol-lipase-as-a-target-a-Pasquarelli-Engelskirchen/e45ef4418e7376c4fc754d6d3e773745dea5ca80
Contrasting effects of selective MAGL and FAAH inhibition on dopamine depletion and GDNF expression in a chronic MPTP mouse model of Parkinson’s disease (Germany) (abst–2017) http://www.sciencedirect.com/science/article/pii/S0197018617301687 https://www.semanticscholar.org/paper/Contrasting-effects-of-selective-MAGL-and-FAAH-on-a-Pasquarelli-Porazik/d58b5b21b422a2ac852cfe10e5c78b2fc0a7f46b Monoacylglycerol lipase alpha inhibition alters prefrontal cortex excitability and blunts the consequences of traumatic stress in rat (USA/Canada) (abst-2020) https://www.sciencedirect.com/science/article/abs/pii/S0028390820300307
KN38-7271/BAY38-7271
Early Survival of Comatose Patients after Severe Traumatic Brain Injury with the Dual Cannabinoid CB1/CB2 Receptor Agonist KN38-7271: A Randomized, Double-Blind, Placebo-Controlled Phase II Trial (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22696266
Cannabinoid Receptor Subtypes 1 and 2 Mediate Long-Lasting Neuroprotection and Improve Motor Behaviour Deficits After Transient Focal Cerebral Ischemia (abst–2012) https://www.sciencedirect.com/science/article/abs/pii/S0306452212010123?via%3Dihub
LBP-1
Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain (abst-2012) http://www.sciencedirect.com/science/article/pii/S0960894X12002405
LEI-105
A highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons (Netherlands/USA/Italy) (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773911/
LH–21
The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet- induced obese pre-diabetic mice (Spain/UK/Brazil) (full–2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479807/
LH-21 and Abn-CBD improve β-cell function in isolated human and mouse islets through GPR55-dependent and -independent signalling (UK/Spain) (link to download–2017) https://kclpure.kcl.ac.uk/portal/files/97046207/data_proof_2.pdf
LH-21, A Peripheral Cannabinoid Receptor 1 Antagonist, Exerts Favorable Metabolic Modulation Including Antihypertensive Effect in KKAy Mice by Regulating Inflammatory Cytokines and Adipokines on Adipose Tissue (China) (full–2018) https://www.frontiersin.org/articles/10.3389/fendo.2018.00167/full
LV-50
Anti-Proliferative Properties and Proapoptotic Function of New CB2 Selective Cannabinoid Receptor Agonist in Jurkat Leukemia Cells (Italy) (full–2018) http://www.mdpi.com/1422-0067/19/7/1958/htm
LY21813240
Arvanil, olvanil, AM 1172 and LY 2183240 (various cannabinoid CB1 receptor agonists) increase the threshold for maximal electroshock-induced seizures in mice (Poland) (abst–2018) https://www.semanticscholar.org/paper/Arvanil%2C-olvanil%2C-AM-1172-and-LY-2183240-(various-Tutka-Wla%C5%BA/7a78fa93122b8296e83888c29e0ab5325d2fb6fd
Anticonvulsive effects of endocannabinoids; an investigation to determine the role of regulatory components of endocannabinoid metabolism in the Pentylenetetrazol induced tonic-clonic seizures. (Iran/ Canada) (abst – 2018) https://link.springer.com/article/10.1007%2Fs11011-018-0195-5
https://www.semanticscholar.org/paper/Anticonvulsive-effects-of-endocannabinoids%3B-an-to-Zareie-Sadegh/56ce2ac02c3f4217ea9c32864c7fea5988a34f06
LY2828360
The slowly signaling G protein-biased CB2 cannabinoid receptor agonist LY2828360 suppresses neuropathic pain with sustained efficacy and attenuates morphine tolerance and dependence (USA) (full–2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749492/
LY3038404 HCl
Cannabinoid receptor 2 agonist attenuates pain related behavior in rats with chronic alcohol / high fat diet induced pancreatitis (full–2014) http://journals.sagepub.com/doi/full/10.1186/1744-8069-10-66
MAB-CHMINACA/ADB-CHMINACA
Postmortem distribution of MAB-CHMINACA in body fluids and solid tissues of a human cadaver (Japan) (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525191/
Case Series of Synthetic Cannabinoid Intoxication from One Toxicology Center (USA) (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899060/
Identification of New Synthetic Cannabinoid ADB-CHMINACA (MAB-CHMINACA) Metabolites in Human Hepatocytes. (USA) (full – 2016) http://link.springer.com/article/10.1208%2Fs12248-016-0037-5
Schedules of Controlled Substances: Temporary Placement of the Synthetic Cannabinoid MAB-CHMINACA Into Schedule I. Final order (full–2016) https://www.federalregister.gov/documents/2015/09/16/2015-23198/schedules-of-controlled-substances-temporary-placement-of-the-synthetic-cannabinoid-mab-chminaca
Acute intoxication of four individuals following use of the synthetic cannabinoid MAB- CHMINACA (Poland) (abst–2016) https://www.semanticscholar.org/paper/Acute-intoxication-of-four-individuals-following-of-Adamowicz-Giero%C5%84/0f007aff43e55616ca2e88d7502ce9882c45a202
Identification and quantification of synthetic cannabinoids in “spice-like” herbal mixtures: Update of the German situation for the spring of 2016. (abst – 2016) https://www.semanticscholar.org/paper/Identification-and-quantification-of-synthetic-in-Langer-Lindigkeit/8bbe63eeecfbea8ce4c81e66aecb71b34f6237f4
Severe illness associated with reported use of synthetic cannabinoids: a public health investigation (Mississippi, 2015). (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29989463
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MAM-2201
Toxicological Findings of Synthetic Cannabinoids in Recreational Users. (full – 2013) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bkt068
Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S0041008X13004766
Symptoms, toxicities, and analytical results for a patient after smoking herbs containing the novel synthetic cannabinoid MAM-2201. (abst – 2013) http://link.springer.com/article/10.1007/s11419-012-0166-1
LC-QTOF-MS as a superior strategy to immunoassay for the comprehensive analysis of synthetic cannabinoids in urine (full–2014) https://docksci.com/lc-qtof-ms-as-a-superior-strategy-to-immunoassay-for-the-comprehensive-analysis-_5b09a5d4d64ab21f2e7c9b8e.html
Determination of major metabolites of MAM-2201 and JWH-122 in in vitro and in vivo studies to distinguish their intake (full–2014) https://docksci.com/determination-of-major-metabolites-of-mam-2201-and-jwh-122-in-in-vitro-and-in-vi_5a94dac5d64ab25d285fcf1d.html
Urinary prevalence, metabolite detection rates, temporal patterns and evaluation of suitable LC-MS/MS targets to document synthetic cannabinoid intake in US military urine specimens (link to PDF–2014) https://www.researchgate.net/publication/266263177_Urinary_prevalence_metabolite_detection_rates_temporal_patterns_and_evaluation_of_suitable_LC-MSMS_targets_to_document_synthetic_cannabinoid_intake_in_US_military_urine_specimens
Inhibitory effect of synthetic cannabinoids on CYP1A activity in mouse liver microsomes. (link to PDF–2014) https://www.jstage.jst.go.jp/article/jts/39/6/39_815/_article
Driving under the influence of synthetic cannabinoids (“Spice”): a case series (link to PDF–2014) https://www.researchgate.net/publication/236602999_Driving_under_the_influence_of_synthetic_cannabinoids_Spice_A_case_series
Identification and quantification of synthetic cannabinoids in ‘spice-like’ herbal mixtures: A snapshot of the German situation in the autumn of 2012 (download–2014) https://europepmc.org/article/med/22710567
MAM-2201 (Analytically Confirmed) Intoxication After “Synthacaine” Consumption (abst–2014) https://www.semanticscholar.org/paper/MAM-2201-(analytically-confirmed)-intoxication-Lonati-Buscaglia/b0d6504a515ad36cda72e53c06477bef59a6ac54
Simultaneous determination of five naphthoylindole-based synthetic cannabinoids and metabolites and their deposition in human and rat hair. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0731708514004427
Emerging drugs of abuse: current perspectives on synthetic cannabinoids. (France) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622447/
A Synthetic Cannabinoid MAM-2201 Potently Suppresses Synaptic Transmission via Activation of Presynaptic CB1 Receptors and Reduces Synaptically-Evoked Intracellular Ca2+ Transients in Cerebellar Purkinje Cells. (Japan) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0028390815000817
Metabolome disruption of the rat cerebrum induced by the acute toxic effects of the synthetic cannabinoid MAM-2201. (Japan) (abst – 2015) https://www.semanticscholar.org/paper/Metabolome-disruption-of-the-rat-cerebrum-induced-Zaitsu-Hayashi/fe915b67a39d7ca15af5a8843665c4ca08eb5c3a
Death due to diabetic ketoacidosis: Induction by the consumption of synthetic cannabinoids? (Germany) (link to download – 2015) https://www.sciencedirect.com/science/article/pii/S0379073815003564?via%3Dihub
Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons. (Canada) (link to PDF– 2016) https://www.researchgate.net/publication/303713782_Pharmacological_characterization_of_emerging_synthetic_cannabinoids_in_HEK293T_cells_and_hippocampal_neurons
Effect of synthetic cannabinoids on spontaneous neuronal activity: Evaluation using Ca2+ spiking and multi-electrode arrays. (Canada) (click “open access” then “ncrpublicationscanadaca” for download – 2016) https://www.semanticscholar.org/paper/Effect-of-synthetic-cannabinoids-on-spontaneous-and-Tauskela-Comas/2932e8404f4116dc42820c86d36646a37b1ccdc0 Trends of novel psychoactive substances (NPSs) and their fatal cases. (Republic of Korea) (abst – 2016) http://link.springer.com/article/10.1007/s11419-015-0286-5
https://www.semanticscholar.org/paper/Trends-of-novel-psychoactive-substances-(NPSs)-and-Chung-Lee/3e8f3d20fd37da12563d59a75a49915101c89401
Acute Effects of Synthetic Cannabinoids: Update 2015. (France) (abst – 2016) https://www.semanticscholar.org/paper/Acute-effects-of-synthetic-cannabinoids%3A-Update-Tournebize-Gibaja/a2a9b8b350237715f8b58475580b4ffa05ea1adc
Metabolic characterization of (1-(5-fluoropentyl)-1H-indol-3-yl)(4-methyl-1- naphthalenyl)-methanone (MAM-2201) using human liver microsomes and cDNA- overexpressed cytochrome P450 enzymes. (abst – 2016) http://link.springer.com/article/10.1007%2Fs00216-016-0113-9
Motor vehicle collisions caused by the ‘super-strength’ synthetic cannabinoids, MAM- 2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014. (Japan) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486620/
Inhibition of cytochrome P450 and uridine 5′-diphospho-glucuronosyltransferases by MAM-2201 in human liver microsomes. (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28484907
Finding order in chemical chaos – Continuing characterization of synthetic cannabinoid receptor agonists. (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0028390817305087?via%3Dihub
https://www.semanticscholar.org/paper/Finding-order-in-chemical-chaos-Continuing-of-Marusich-Wiley/6887e7a0887f110091a9c5228b5eb9223f3bc9f2 Metabolism of Synthetic Cannabinoid Receptor Agonists Encountered in Clinical Casework: Major in vivo Phase I Metabolites of JWH-007, JWH-019, JWH-203, JWH-307, UR-144, XLR-11, AM-2201, MAM-2201 and AM-694 in Human Urine Using LC- MS/MS. (Germany/ UK) (click “View PDF” for download – 2018) https://www.semanticscholar.org/paper/Metabolism-of-synthetic-cannabinoid-receptor-in-in-Hutter-Br%C3%B6cker/a5361519e2ebccf8bbe493e6bc39d23790e8e722
MARINOL/DRONABINOL
Delta9-tetrahydrocannabivarin testing may not have the sensitivity to detect marijuana use among individuals ingesting dronabinol. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815025/?tool=pubmed
DEA- Listing of Approved Drug Products Containing Dronabinol in Schedule III. (USA) (full – 2010) https://www.deadiversion.usdoj.gov/fed_regs/rules/2010/fr1101.htm
Nutritional Interventions for Cancer-induced Cachexia. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106221/
Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325767/
Dramatic improvement of refractory Isaacs’ syndrome after treatment with dronabinol. (full – 2010) http://www.onlinepot.org/medical/IsaacsSyndrom.htm
Use of dronabinol (delta-9-THC) in autism: A prospective single-case-study with an early infantile autistic child. (link to download – 2010) http://www.cannabis-med.org/data/pdf/en_2010_04_1.pdf
Marijuana: Medical Applications, Recreational Use and Substance Abuse Disorders. (link to download – 2010) http://www.eurekaselect.com/85221/article
Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study. (abst – 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=313
Dronabinol for the treatment of unspecific pain, restlessness and spasticity in neuropaediatrics. (abst – 2010) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1265622
Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients with Non-Constipated Irritable Bowel Syndrome. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202649/
Subjective and physiological effects after controlled Sativex and oral THC administration. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836266/
Combined effects of acute, very-low-dose ethanol and delta(9)-tetrahydrocannabinol in healthy human volunteers. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018238/
Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial. (full – 2011) https://academic.oup.com/annonc/article/22/9/2086/211788/Delta-9-tetrahydrocannabinol-may-palliate-altered
Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trial. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154755/
Antagonist-elicited cannabis withdrawal in humans. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717344/
Oral Fluid and Plasma Cannabinoid Ratios after Around-the-Clock Controlled Oral {Delta}9-Tetrahydrocannabinol Administration. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836268/
Room-temperature stable dronabinol formulations – Patent NZ555701 (A) ― 2011- 05-27 (full-2011) http://worldwide.espacenet.com/publicationDetails/description?CC=NZ&NR=555701A&KC=A&FT=D&ND=3&date=20110527&D
B=EPODOC&locale=en_EP Dronabinol, a cannabinoid agonist, reduces hair pulling in trichotillomania: a pilot study. (link to PDF – 2011) https://www.researchgate.net/publication/51144698_Dronabinol_a_cannabinoid_agonist_reduces_hair_pulling_in_trichotillomania_A_pilot_study
Cannabinoids in children (abst–2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=295
Early exposure to Environmental enrichment alters the expression of genes of the endocannabinoid system (abst–2011) https://www.sciencedirect.com/science/article/pii/S0006899311005221
A randomized, double-blind, placebo-controlled, crossover study to evaluate the subjective abuse potential and cognitive effects of nabiximols oromucosal spray in subjects with a history of recreational cannabis use. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21671456
Endocannabinoids in nervous system health and disease: the big picture in a nutshell. (full – 2012) http://rstb.royalsocietypublishing.org/content/367/1607/3193.full
Tolerance to Effects of High-Dose Oral {Delta}9-Tetrahydrocannabinol and Plasma Cannabinoid Concentrations in Male Daily Cannabis Smokers. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584989/
The Therapeutic Potential of Cannabis and Cannabinoids. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442177/
Can oral fluid cannabinoid testing monitor medication compliance and/or cannabis smoking during oral THC and oromucosal Sativex administration? (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612560/
The dose effects of short-term dronabinol (oral THC) maintenance in daily cannabis users. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546149/
Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome (full–2012) http://ajpgi.physiology.org/content/302/10/G1075
Effects of delta-9-tetrahydrocannabinol on evaluation of emotional images (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664416/
Genetic Epidemiology and Pharmacogenetics in Irritable Bowel Syndrome. (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362100/
Randomized pharmacodynamic and pharmacogenetic trial of dronabinol effects on colon transit in irritable bowel syndrome-diarrhea. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775711/
Subjective, cognitive and cardiovascular dose-effect profile of nabilone and dronabinol in marijuana smokers. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335956/
Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities. (full – 2012) http://rstb.royalsocietypublishing.org/content/367/1607/3353.full?sid=1569c370-cd5c-4358-89ff-857201f5e069
Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417459/
Heat Exposure of Cannabis sativa Extracts Affects the Pharmacokinetic and Metabolic Profile in Healthy Male Subjects. (link to PDF – 2012) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Heat+Exposure+of+Cannabis+sativa+Extracts+Affects+the+Pharmacokinetic+and+Metabolic+Profile+in+Healthy+Male+Subjects.++++++++++++&btnG=
DRONABINOL capsule. [Watson Laboratories, Inc.] (monograph – 2012) http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5bbac0b1-ddc2-400b-8e0d-1e1d484720ca
Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22491047
Effects of dronabinol on morphine-induced dopamine-related behavioral effects in animals. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22807156
THCVA-A – a new additional marker for illegal cannabis consumption. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S0379073811001150
Proof of concept trial of dronabinol in obstructive sleep apnea. (full – 2013) http://www.frontiersin.org/Sleep_Disorders/10.3389/fpsyt.2013.00001/full
Pharmacokinetic and Pharmacodynamic Profile of Supratherapeutic Oral Doses of Δ9 – THC in Cannabis Users. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691290/
Cannabinoid facilitation of fear extinction memory recall in humans. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445738/
Towards a better Cannabis drug. (full – 2013) http://onlinelibrary.wiley.com/doi/10.1111/bph.12400/full
The medical use of cannabis for reducing morbidity and mortality in patients with HIV/AIDS. (full – 2013) http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005175.pub3/full
Plasma Cannabinoid Concentrations During Dronabinol Pharmacotherapy for Cannabis Dependence. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955404/
A human laboratory study investigating the effects of quetiapine on marijuana withdrawal and relapse in daily marijuana smokers. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465638/
The Subjective Psychoactive Effects of Oral Dronabinol Studied in a Randomized, Controlled Crossover Clinical Trial For Pain. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013220/
Intranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in Sprague-Dawley rat. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880550/
Around-the-clock oral THC effects on sleep in male chronic daily cannabis smokers. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537525/
Acute Δ9-tetrahydrocannabinol blocks gastric hemorrhages induced by the nonsteroidal anti-inflammatory drug diclofenac sodium in mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053165/
Oral Fluid Cannabinoids in Chronic Cannabis Smokers during Oral Δ9- Tetrahydrocannabinol Therapy and Smoked Cannabis Challenge. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102264/
Effect of dronabinol on progression in progressive multiple sclerosis (CUPID): a randomised, placebo-controlled trial. (full – 2013) http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70159-5/fulltext
Nabilone decreases marijuana withdrawal and a laboratory measure of marijuana relapse. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682150/
The pharmacologic and clinical effects of medical cannabis. (download – 2013) The Pharmacologic and Clinical Effects of Medical Cannabis The cannabis conundrum. (USA) (article – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808660/
Suspected Dronabinol Withdrawal in an Elderly Cannabis-Naive Medically Ill Patient (letter–2013) http://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.2013.13010059
Medicinal Cannabis and Painful Sensory Neuropathy. (editorial – 2013) https://journalofethics.ama-assn.org/article/medicinal-cannabis-and-painful-sensory-neuropathy/2013-05
Simultaneous and sensitive LC–MS/MS determination of tetrahydrocannabinol and metabolites in human plasma. (abst – 2013) http://link.springer.com/article/10.1007/s00216-012-6501-x
Synthetic cannabis: A comparison of patterns of use and effect profile with natural cannabis in a large global sample. (UK/ Australia) (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23291209
Dronabinol Treatment of Refractory Nausea and Vomiting Related to Peritoneal Carcinomatosis. (abst – 2013) http://ajh.sagepub.com/content/32/1/5.long
Acyl migration evaluation in monoacylglycerols from Echium plantagineum seed oil and Marinol. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S1389172312004744
Getting high on the endocannabinoid system. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295/
Cannabinoid Type 1 and Type 2 Receptor Antagonists Prevent Attenuation of Serotonin- Induced Reflex Apneas by Dronabinol in Sprague-Dawley Rats (full–2014) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0111412
Medical marijuana for cancer. (full – 2014) http://onlinelibrary.wiley.com/doi/10.3322/caac.21260/full
Impact of dronabinol on quantitative electroencephalogram (qEEG) measures of sleep in obstructive sleep apnea syndrome. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869068/
Medical marijuana: more questions than answers. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243838/
Cannabinoid modulation of prefrontal-limbic activation during fear extinction learning and recall in humans. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960373/
Genetic identification of Cannabis sativa using chloroplast trnL-F gene. (full – 2014) https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S1872497314002191?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1872497314002191%3Fshowall%3Dtrue&referrer=
Effect of dronabinol therapy on physical activity in anorexia nervosa: a randomised, controlled trial. (link to PDF – 2014) https://scholar.google.com/scholar?q=Effect+of+dronabinol+therapy+on+physical+activity+in+anorexia+nervosa:+a+randomised,+controlled+trial&hl=en&as_sdt=0&as_vis=1&oi=scholart
Clinical evaluation and optimal management of cancer cachexia. (link to PDF – 2014) https://www.researchgate.net/publication/255974146_Clinical_evaluation_and_optimal_management_of_cancer_cachexia
Early phytocannabinoid chemistry to endocannabinoids and beyond. (Israel/ Scotland/ USA) (link to PDF– 2014) https://www.researchgate.net/publication/266945311_Early_phytocannabinoid_chemistry_to_endocannabinoids_and_beyond
Dronabinol and chronic pain: importance of mechanistic considerations. (click “runl” for download – 2014) https://scholar.google.com/scholar?q=Dronabinol+and+chronic+pain:+importance+of+mechanistic+considerations.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Report on Medical Cannabis Research History- What the Science Says (USA) (article–2014) http://www.safeaccessnow.org/medical_cannabis_research_what_does_the_evidence_say
Fibromyalgia. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24365316
Dronabinol for the treatment of agitation and aggressive behavior in acutely hospitalized severely demented patients with noncognitive behavioral symptoms. (abst – 2014) https://www.semanticscholar.org/paper/Dronabinol-for-the-treatment-of-agitation-and-in-Woodward-
Harper/3fcd1706a7b7e15abfa193d9f745dbe1e18aa378 Dronabinol in severe, enduring anorexia nervosa: A randomized controlled trial. (abst – 2014) https://www.semanticscholar.org/paper/Dronabinol-in-severe%2C-enduring-anorexia-nervosa%3A-a-Andrie%C5%9F-Frystyk/d230636e53c4ec93decc3c01da4081a09163e917
There is evidence for the use of cannabinoids for symptomatic treatment of multiple sclerosis. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25350886
Pharmacotherapy of trichotillomania (hair pulling disorder): an updated systematic review. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25399534
Cannabinoid Type 1 Receptor Antagonist, AM251, Prevents Attenuation Of Serotonin- induced Apneas By Dronabinol In Sprague-Dawley Rats. (abst – 2014) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2014.189.1_MeetingAbstracts.A3901
Plant derived substances with anti-cancer activity: from folklore to practice. (Israel) (full – 2015) http://journal.frontiersin.org/article/10.3389/fpls.2015.00799/full
Emerging drugs of abuse: current perspectives on synthetic cannabinoids. (France) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622447/
Small Molecules from Nature Targeting G-Protein Coupled Cannabinoid Receptors: Potential Leads for Drug Discovery and Development. (United Arab Emirates/ India/ USA/Saudi Arabia) (full – 2015) http://www.hindawi.com/journals/ecam/2015/238482/
Prevalence and determinants of cannabinoid prescription for the management of chronic noncancer pain: a postal survey of physicians in the Abitibi-Témiscamingue region of Quebec. (Canada) (full – 2015) http://cmajopen.ca/content/3/2/E251.full?sid=139f05c1-b441-476b-99ff-addf8c918e1a
Comparing treatment effects of oral THC on simulated and on-the-road driving performance: testing the validity of driving simulator drug research . (Netherlands/ Germany) (full – 2015) http://link.springer.com/article/10.1007/s00213-015-3927-9/fulltext.html
Sequelae of Cannabis as Medicine. (USA) (full – 2015) http://painmedicine.oxfordjournals.org/content/16/7/1447
Safety, pharmacodynamics, and pharmacokinetics of multiple oral doses of delta-9- tetrahydrocannabinol in older persons with dementia. (Netherlands) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480847/
Cannabis in the Treatment of Dystonia, Dyskinesias, and Tics. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604174/
Safety of oral dronabinol during opioid withdrawal in humans. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663169/
The effects of dronabinol during detoxification and the initiation of treatment with extended release naltrexone. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536087/
Clinical perspectives on medical marijuana (cannabis) for neurologic disorders. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549715/
Clinical Use of Cannabinoids for Symptom Control in Multiple Sclerosis (UK) (full–2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604175/
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Dronabinol and lofexidine for cannabis use disorder: A randomized, double-blind, placebo-controlled trial. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729291/
Current Status and Future of Cannabis Research. (USA) (link to PDF– 2015) https://www.researchgate.net/publication/273573870_Current_status_and_future_of_cannabis_research
Pharmacogenetics in irritable bowel syndrome. (USA) (link to download – 2015) http://informahealthcare.com/doi/pdf/10.1517/17425255.2015.1048223
Do Cannabinoid Receptor Agonists Have A Role In The Intensive Care Unit? … Totally Dude! (USA) (1st page–2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1657
Changes in IGF-I, urinary free cortisol and adipokines during dronabinol therapy in anorexia nervosa: Results from a randomised, controlled trial. (Denmark) (abst–2015) https://www.sciencedirect.com/science/article/abs/pii/S1096637415300174
A state-of-the-art review of the management and treatment of taste and smell alterations in adult oncology patients (Canada) (click “researchgate” for download– 2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22A+state-of-the-
art+review+of+the+management+and+treatment+of+taste+and+smell+alterations+in+adult+oncology+patients.+++++++%22&btnG
Effect of oral THC pretreatment on marijuana cue-induced responses in cannabis dependent volunteers. (USA) (click “academia” for download – 2015) https://scholar.google.com/scholar?q=%22Effect+of+oral+THC+pretreatment+on+marijuana+cue-induced+responses+in+cannabis+dependent+volunteers%22&hl=en&as_sdt=0&as_vis=1&oi=scholart
Emerging Drugs for Common Conditions of Sleepiness: Obstructive Sleep Apnea and Narcolepsy. (USA) (abst – 2015) http://www.tandfonline.com/doi/full/10.1517/14728214.2015.1115480
Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease. (Canada) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26271310
A 4-Week Pilot Study With the Cannabinoid Receptor Agonist Dronabinol and Its Effect on Metabolic Parameters in a Randomized Trial. (USA) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26283236
Dronabinol has preferential antileukemic activity in acute lymphoblastic and myeloid leukemia with lymphoid differentiation patterns. (Germany) (full – 2016) http://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-2029-8
Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview. (Italy) (full – 2016) http://www.mdpi.com/1420-3049/21/4/518/htm
Intracerebroventricular injections of dronabinol, a cannabinoid receptor agonist, does not attenuate serotonin-induced apnea in Sprague-Dawley rats (USA) (full–2016) http://jnrbm.biomedcentral.com/articles/10.1186/s12952-016-0052-1
Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869612/
Chronic Δ9-Tetrahydrocannabinol Administration Reduces IgE+B Cells but Unlikely Enhances Pathogenic SIVmac251 Infection in Male Rhesus Macaques of Chinese Origin (China/ USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008029/
Opioid withdrawal suppression efficacy of oral dronabinol in opioid dependent humans. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910823/
Cannabinoids, inflammation, and fibrosis. (USA) (full – 2016) https://www.fasebj.org/doi/full/10.1096/fj.201600646R
Cannabinoids for Symptom Management and Cancer Therapy: The Evidence. (USA) (full – 2016) https://jnccn.org/view/journals/jnccn/14/7/article-p915.xml
ENDOCANNABINOID SYSTEM: A multi-facet therapeutic target (India) (link to PDF–2016) https://www.researchgate.net/publication/301533431_Endocannabinoid_System_A_Multi-Facet_Therapeutic_Target
Edible Cannabis Products: It is Time for FDA Oversight (USA) (link to download–2016) http://www.accp1.org/documents/2016BenjaminEdibleCannabisProducts.pdf Efficacy, tolerability and safety of cannabinoids for chronic neuropathic pain : A systematic review of randomized controlled studies (Germany) (abst in English & German–2016) http://link.springer.com/article/10.1007%2Fs00482-015-0089-y
Dronabinol increases pain threshold in patients with functional chest pain: a pilot double- blind placebo-controlled trial. (USA) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26822791
Cannabinoids: Medical implications. (USA) (abst – 2016) https://www.semanticscholar.org/paper/Cannabinoids%3A-Medical-implications.-Schrot-Hubbard/2aab2c83e7a45a160550cdad7a2c877e02b2c9cc
Investigational drugs for treating agitation in persons with dementia. (France/ USA) (abst – 2016) https://www.tandfonline.com/doi/abs/10.1080/13543784.2016.1193155
https://www.semanticscholar.org/paper/Investigational-drugs-for-treating-agitation-in-Garay-Citrome/822a91ef37596c81031c95037b377631a4e11673
An Overlooked Victim of Cannabis: Losing Several Years of Well-being and Inches of Jejunum on the Way to Unravel Her Hyperemesis Enigma. (Germany) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26757305
Effective treatment of spasticity using dronabinol in pediatric palliative care. (Germany) (abst – 2016) https://www.sciencedirect.com/science/article/abs/pii/S1090379816301271
Stability of dronabinol capsules when stored frozen, refrigerated, or at room temperature (USA) (abst–2016) https://www.semanticscholar.org/paper/Stability-of-dronabinol-capsules-when-stored-or-at-Wempe-Oldland/fc5c2bdd385d78d030c162acd86057550182fcbc
Mice expressing a “hyper-sensitive” form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398885/
The Use of Cannabis for Headache Disorders. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436334/
A Guide to the National Academy of Science Report on Cannabis: An Exclusive Discussion with Panel Members. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569624/
Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go? (Germany/ Austria) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388177/
The endocannabinoid system and its therapeutic exploitation in multiple sclerosis: Clues for other neuroinflammatory diseases . (Italy) (full – 2017) http://www.sciencedirect.com/science/article/pii/S0301008217300709?via%3Dihub
Effects of chronic Δ9-tetrahydrocannabinol treatment on Rho/Rho-kinase signalization pathway in mouse brain. (Turkey) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681306/
The Use of Medical Cannabis with Other Medications: A Review of Safety and Guidelines [Internet]. (Canada) (full – 2017) https://www.ncbi.nlm.nih.gov/books/NBK470766/
Effects of Cannabinoid Agonists and Antagonists on Sleep and Breathing in Sprague- Dawley Rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806547/
Speechlessness in Gilles de la Tourette Syndrome: Cannabis-Based Medicines Improve Severe Vocal Blocking Tics in Two Patients. (Germany) (full – 2017) http://www.mdpi.com/1422-0067/18/8/1739/htm
Pharmacotherapy of Apnea by Cannabimimetic Enhancement, the PACE Clinical Trial: Effects of Dronabinol in Obstructive Sleep Apnea. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806568/
Selective Cannabinoids for Chronic Neuropathic Pain: A Systematic Review and Meta- analysis. (Canada) (full – 2017) https://journals.lww.com/anesthesia-analgesia/Fulltext/2017/11000/Selective_Cannabinoids_for_Chronic_Neuropathic.32.aspx
Guanfacine Attenuates Adverse Effects of Dronabinol (THC) on Working Memory in Adolescent-Onset Heavy Cannabis Users: A Pilot Study. (USA) (full – 2017) https://neuro.psychiatryonline.org/doi/full/10.1176/appi.neuropsych.16120328?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed Cannabis Use in Palliative Oncology: A Review of the Evidence for Popular Indications. (Israel) (link to PDF – 2017) https://www.ima.org.il/IMAJ/ViewArticle.aspx?aId=4043
Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. (Israel) (link to PDF – 2017) http://www.painphysicianjournal.com/linkout?issn=1533-3159&vol=20&page=E755
The endocannabinoid system as a target for addiction treatment: Trials and tribulations. (Canada/ USA) (link to PDF – 2017) https://www.researchgate.net/publication/317252828_The_endocannabinoid_system_as_a_target_for_addiction_treatment_Trials_and_tribulations
Cannabis, Cannabinoids, and Sleep: a Review of the Literature. (USA) (link to download – 2017) https://www.med.upenn.edu/cbti/assets/user-content/documents/s11920-017-0775-9.pdf
Schedules of Controlled Substances: Placement of FDA-Approved Products of Oral Solutions Containing Dronabinol [(-)-delta-9-trans- tetrahydrocannabinol (delta-9-THC)] in Schedule II. Final rule. (click “LinkOut” for download – 2017) https://www.ncbi.nlm.nih.gov/pubmed/29232070
Cannabis for Pain and Headaches: Primer. (USA) (abst – 2017) https://link.springer.com/article/10.1007%2Fs11916-017-0619-7
https://www.semanticscholar.org/paper/Cannabis-for-Pain-and-Headaches%3A-Primer.-Kim-Fishman/bebc1e9df306be62c4332f218c91658f9cfc4ea2
Marijuana and other cannabinoids as a treatment for posttraumatic stress disorder: A literature review. (USA) (abst – 2017) https://www.researchgate.net/publication/314126850_Marijuana_and_other_cannabinoids_as_a_treatment_for_posttraumatic_stress_disorder_A_literature_review Cannabinoids for nausea and vomiting related to chemotherapy: Overview of systematic reviews. (Brazil) (abst – 2017) https://onlinelibrary.wiley.com/doi/full/10.1002/ptr.5975
An update on the advancements in the treatment of agitation in Alzheimer’s disease. (USA) (abst – 2017) https://www.tandfonline.com/doi/abs/10.1080/14656566.2017.1307340?journalCode=ieop20
Cannabinoid Receptors in Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance. (Austria/ Germany) (abst – 2017) https://link.springer.com/chapter/10.1007%2F164_2016_105
Dronabinol. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/books/NBK501596/
Dronabinol oral solution in the management of anorexia and weight loss in AIDS and cancer. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896684/
Medical Cannabis and the Treatment of Obstructive Sleep Apnea: An American Academy of Sleep Medicine Position Statement. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886446/
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis. (Italy) (full – 2018) http://www.mdpi.com/2305-6320/5/3/91/htm
Cannabinoids for Behavioural Symptoms in Adults with Dementia: A Review of Clinical Effectiveness and Guidelines. (Spain/ USA) (full – 2018) https://www.ncbi.nlm.nih.gov/books/NBK526373/
Cannabis in palliative care: current challenges and practical recommendations. (Canada/ USA) (full – 2018) http://apm.amegroups.com/article/view/20097/21242
Erratum to cannabis in palliative care: current challenges and practical recommendations. (Canada/ USA) (erratum – 2018) http://apm.amegroups.com/article/view/23880/23545
Pharmaceutical cannabinoid use in Manitoba, 2004/05 to 2014/15: a population-based cross-sectional study. (Canada) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298870/
The effect of high-dose dronabinol (oral THC) maintenance on cannabis self- administration. (USA) (full – 2018) https://europepmc.org/articles/pmc5959782
Cannabinoids and gastrointestinal motility: Pharmacology, clinical effects, and potential therapeutics in humans. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150799/
Medical Cannabis and AASM Position Statement: The Don’t Ask, Don’t Tell Wishing Well. (USA) (letter – 2018) http://jcsm.aasm.org/ViewAbstract.aspx?pid=31418
Stop the Attack on Minnesota’s Courageous Stance to Allow Its Residents to Sleep Safely. (USA) (letter – 2018) http://jcsm.aasm.org/ViewAbstract.aspx?pid=31419
Medical Cannabis, Synthetic Marijuana Extracts, and Obstructive Sleep Apnea. (USA) (letter – 2018) http://jcsm.aasm.org/ViewAbstract.aspx?pid=31420
Medical use of cannabis and cannabinoids containing products – Regulations in Europe and North America. (Israel) (abst– 2018) https://www.ejinme.com/article/S0953-6205(18)30001-3/fulltext
https://www.semanticscholar.org/paper/Medical-use-of-cannabis-and-cannabinoids-containing-Abuhasira-
Shbiro/2adff3a9a89097f281582abc123c2744c5ac6db6 Should Cannabinoids Be Added to Multimodal Pain Regimens After Total Hip and Knee Arthroplasty? (USA) (abst – 2018) https://www.arthroplastyjournal.org/article/S0883-5403(18)30670-3/fulltext
2019 Cannabis and Cannabinoids (PDQ®) Patient Version. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK65875/
2019 Cannabis and Cannabinoids (PDQ®)Health Professional Version. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK65755/
Medicinal use of cannabis based products and cannabinoids. (UK) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447998/
Antiemetic Agents. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK548071/
Dronabinol. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK548830/
Medical Cannabis for the Treatment of Dementia: A Review of Clinical Effectiveness and Guidelines [Internet]. (Canada) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK546328/
Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders (USA) (click “researchgate” for download – 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Potential+of+Cannabinoid+Receptor+Ligands+as+Treatment+for+Substance+Use+Disorders%22&btnG Dronabinol-Induced
Hypomania: A Case Report and Literature Review. (USA) (click “semanticscholar” for download – 2019) https://www.researchgate.net/publication/335239653_Dronabinol-induced_hypomania_A_case_report_and_literature_review
Cannabis for medical purposes : Impact of the law of 6 March 2017 on physicians. (Germany) (abst in English & German – 2019) https://link.springer.com/article/10.1007%2Fs00482-019-0387-x
High-dose dronabinol treatment vs. medicinal cannabis flowers. (Germany) (abst in English & German–2019) https://link.springer.com/article/10.1007%2Fs00482-019-00402-7
Dronabinol in geriatric pain and palliative care patients. (Germany) (abst in English & German – 2019) https://link.springer.com/article/10.1007%2Fs00482-019-00408-1
The use of cannabis-based drugs in pain and palliative medicine : Joint online questionnaire conducted by the Professional Association of Physicians and Psychotherapists in Pain and Palliative Medicine in Germany (BVSD), the German Pain Society, and the German Society for Pain Medicine (DGS). (Germany) (abst in English & German – 2019) https://link.springer.com/article/10.1007%2Fs00482-019-00406-3
Dark Classics in Chemical Neuroscience: Δ9-Tetrahydrocannabinol. (Australia/ New Zealand) (abst – 2019) https://pubs.acs.org/doi/10.1021/acschemneuro.8b00651
Delta-9-tetrahydrocannabinol intoxication is associated with increased prefrontal activation as assessed with functional near-infrared spectroscopy: A report of a potential biomarker of intoxication. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S1053811919303957?via%3Dihub
Dronabinol for the Treatment of Paraneoplastic Night Sweats in Cancer Patients: A Report of Five Cases. (USA) (abst– 2019) https://www.ncbi.nlm.nih.gov/pubmed/30759037
Dronabinol use in France between 2004 and 2017. (France) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0035378717308019
Treatment of Gilles de la Tourette Syndrome with Cannabis-Based Medicine: Results from a Retrospective Analysis and Online Survey. (Poland/ Germany) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31872061
Impact of Cannabinoids on Symptoms of Refractory Gastroparesis: A Single-center Experience. (USA) (full – 2020) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970440/
MDA-7 – strong CB2 agonist MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models. (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597252/
Adenoviral endoplasmic reticulum-targeted mda-7/interleukin-24 vector enhances human cancer cell killing. (full – 2008) http://mct.aacrjournals.org/content/7/8/2528.long
Prevention of Paclitaxel-Induced Neuropathy Through Activation of the Central Cannabinoid Type 2 Receptor System. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334436/
In vivo efficacy of enabling formulations based on hydroxypropyl-β-cyclodextrins, micellar preparation, and liposomes for the lipophilic cannabinoid CB2 agonist, MDA7. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981967/
Combining histone deacetylase inhibitors with MDA-7/IL-24 enhances killing of renal carcinoma cells. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925659/
Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. (link to PDF – 2013) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Activation+of+the+CB2+receptor+system+reverses+amyloid-induced+memory+deficiency.&btnG=
Spinal gene expression profiling and pathways analysis of a CB2 agonist (MDA7)- targeted prevention of paclitaxel-induced neuropathy. (link to PDF – 2013) https://www.researchgate.net/publication/259448615_Spinal_gene_expression_profiling_and_pathways_analysis_of_a_CB2_agonist_MDA7-targeted_prevention_of_paclitaxel-induced_neuropathy
Activation of Cannabinoid Receptor 2 Attenuates Mechanical Allodynia and Neuroinflammatory Responses in a Chronic Post-Ischemic Pain Model of Complex Regional Pain Syndrome Type I in Rats (USA/China) (click “Alternate Sources”, then “rsdsorg” for download–2016) https://www.semanticscholar.org/paper/Activation-of-cannabinoid-receptor-2-attenuates-and-Xu-Tang/b76958bc75f9e27fdf6bad7f451661111189e311
Stabilization of MDA-7/IL-24 for colon cancer therapy. (abst – 2013) http://www.cancerletters.info/article/S0304-3835(13)00218-8/abstract
Activation of CB2 receptor system restores cognitive capacity and hippocampal Sox2 expression in a transgenic mouse model of Alzheimer’s disease (USA) (link to PDF–2017) https://www.researchgate.net/publication/31714
1246_Activation_of_CB2_receptor_system_restores_cognitive_capacity_and_hippoca mpal_Sox2_expression_in_a_transgenic_mouse_model_of_Alzheimer’s_disease
MDA-7
Prevention of Paclitaxel-Induced Neuropathy Through Activation of the Central Cannabinoid Type 2 Receptor System (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334436/
In vivo efficacy of enabling formulations based on hydroxypropyl-β-cyclodextrins, micellar preparation, and liposomes for the lipophilic cannabinoid CB2 agonist, MDA7. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981967/
Combining histone deacetylase inhibitors with MDA-7/IL-24 enhances killing of renal carcinoma cells. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925659/
Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. (link to PDF – 2013) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Activation+of+the+CB2+receptor+system+reverses+amyloid-induced+memory+deficiency.&btnG=
Spinal gene expression profiling and pathways analysis of a CB2 agonist (MDA7)- targeted prevention of paclitaxel-induced neuropathy. (link to PDF – 2013) https://www.researchgate.net/publication/259448615_Spinal_gene_expression_profiling_and_pathways_analysis_of_a_CB2_agonist_
MDA7-targeted_prevention_of_paclitaxel-induced_neuropathy Activation of Cannabinoid Receptor 2 Attenuates Mechanical Allodynia and Neuroinflammatory Responses in a Chronic Post-Ischemic Pain Model of Complex Regional Pain Syndrome Type I in Rats. (USA/ China) (click “Alternate Sources”, then “rsdsorg” for download – 2016) https://www.semanticscholar.org/paper/Activation-of-cannabinoid-receptor-2-attenuates-and-Xu-Tang/b76958bc75f9e27fdf6bad7f451661111189e311 Stabilization of MDA-7/IL-24 for colon cancer therapy. (abst – 2013) http://www.cancerletters.info/article/S0304-3835(13)00218-8/abstract
Activation of CB2 receptor system restores cognitive capacity and hippocampal Sox2 expression in a transgenic mouse model of Alzheimer’s disease. (USA) (link to PDF – 2017) https://www.researchgate.net/publication/31714
1246_Activation_of_CB2_receptor_system_restores_cognitive_capacity_and_hippoca mpal_Sox2_expression_in_a_transgenic_mouse_model_of_Alzheimer’s_disease
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MDA-19
Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253719/
Studies demonstrate analgesic properties of synthetic cannabinoid (news–2010) http://www.news-medical.net/news/20100702/Studies-demonstrate-analgesic-properties-of-synthetic-cannabinoid.aspx
Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253719/
MDMB-CHMICA Simultaneous detection of 93 synthetic cannabinoids by liquid chromatography-tandem mass spectrometry and retrospective application to real forensic samples (Germany) (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27400642
Quantification of synthetic cannabinoids in herbal smoking blends using NMR (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27400773
MDMB-CHMICA: Availability, Patterns of Use, and Toxicity Associated With This Novel Psychoactive Substance. (UK) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27759479
Identification and quantification of synthetic cannabinoids in “spice-like” herbal mixtures: Update of the German situation for the spring of 2016. (abst – 2016) https://www.semanticscholar.org/paper/Identification-and-quantification-of-synthetic-in-Langer-Lindigkeit/8bbe63eeecfbea8ce4c81e66aecb71b34f6237f4
The impact of the Psychoactive Substances Act 2016 on the online availability of MDMB-CHMICA (link to pdf–2017) https://academic.oup.com/qjmed/article/110/10/619/3057951
Schedules of Controlled Substances: Temporary Placement of Six Synthetic Cannabinoids (5F-ADB, 5F-AMB, 5F-APINACA, ADB-FUBINACA, MDMB- CHMICA and MDMB-FUBINACA) into Schedule I. Temporary Scheduling Order. (click “LinkOut” for download – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28425681
Identification and quantification of synthetic cannabinoids in ‘spice-like’ herbal mixtures: Update of the German situation in early 2017. (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0379073817301901
Clinical and analytical experience of the National Poison Control Centre with synthetic cannabinoids. (Serbia) (full – 2018) https://content.sciendo.com/view/journals/aiht/69/2/article-p178.xml
MDMB-CHMCZA
Characterization of the synthetic cannabinoid MDMB-CHMCZCA. (full -2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238538/
Schedules of Controlled Substances: Temporary Placement of Six Synthetic Cannabinoids (5F-ADB, 5F-AMB, 5F-APINACA, ADB-FUBINACA, MDMB- CHMICA and MDMB-FUBINACA) into Schedule I. Temporary Scheduling Order. (click “LinkOut” for download – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28425681
MJN-110
Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice. (USA) (full – 2015) http://jpet.aspetjournals.org/content/353/2/424.full.pdf+html
For whom the endocannabinoid tolls: Modulation of innate immune function and implications for psychiatric disorders (Ireland) (click “academia” for download–2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=For+whom+the+endocannabinoid+tolls%3A+Modulation+of+innate+immune+function+and+implications+for+psychiatric+disorders.&btnG
Robust anti-nociceptive effects of MAG lipase inhibition in a model of osteoarthritis pain. (UK/ USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056226/
Elevation of 2-AG by monoacylglycerol lipase inhibition in the visceral insular cortex interferes with anticipatory nausea in a rat model. (Canada/ USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793281/
Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959103/
The selective monoacylglycerol lipase inhibitor MJN110 produces opioid sparing effects in a mouse neuropathic pain model. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809319/
Cannabinoid Receptor Interacting Protein (CRIP1a) suppresses agonist-driven CB1 receptor internalization, and regulates receptor replenishment in an agonist-biased manner (full – 2016) https://europepmc.org/article/pmc/pmc5894350#free-full-text
Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771234/
Monoacylglycerol lipase inhibition alters social behavior in male and female rats after post-weaning social isolation. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034682/
FAAH, but not MAGL, inhibition modulates acute TLR3-induced neuroimmune signaling in the rat, independent of sex. (Ireland) (click “nuigalway” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=FAAH%2C+but+not+MAGL%2C+inhibition+modulates+acute+TLR3-induced+neuroimmune+signaling+in+the+rat%2C+independent+of+sex.&btnG
CB₁ receptor antagonism in the bed nucleus of the stria terminalis interferes with affective opioid withdrawal in rats. (Canada/ USA) (abst – 2017) https://www.semanticscholar.org/paper/CB%E2%82%81-receptor-antagonism-in-the-bed-nucleus-of-the-Wills-
DeVuono/180e199c0aca015ece29b7d8dfc2ce3b6a2988ce Nausea-Induced 5-HT Release in the Interoceptive Insular Cortex and Regulation by Monoacylglycerol Lipase (MAGL) Inhibition and Cannabidiol. (Canada) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071201/
Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake. (USA/ Spain) (full – 2018) https://www.nature.com/articles/s41386-018-0055-3
Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced neuropathy. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038031/
Neuroprotective Effects of MAGL (Monoacylglycerol Lipase) Inhibitors in Experimental Ischemic Stroke. (Republic of Korea/ USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829008/
Endocannabinoid degradation inhibitors ameliorate neuronal and synaptic alterations following traumatic brain injury (USA) (abst–2020) https://journals.physiology.org/doi/abs/10.1152/jn.00570.2019
ML-184
Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis. (USA) (full – 2018) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14387
ML-193
The G-protein coupled receptor 55-agonist L-α-lysophosphatidylinositol mediates ovarian carcinoma cell induced angiogenesis. (Austria/ USA) (full– 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543616/
The Lysophosphatidylinositol Receptor GPR55 Modulates Pain Perception in the Periaqueduactal Grey (USA) (full–2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518086/
Central administration of GPR55 receptor agonist and antagonist modulates anxiety- related behaviors in rats. (Iran) (abst – 2015) https://www.semanticscholar.org/paper/Central-administration-of-GPR55-receptor-agonist-in-Rahimi-Moghaddam/d056ca05ce2ef0ba0853de4606aa3e14c356e50c
N-arachidonoyl glycine, another endogenous agonist of GPR55. (full – 2017) https://europepmc.org/articles/pmc5576593
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MM-433593
Metabolism and disposition of MM-433593, a selective FAAH-1 inhibitor, in monkeys (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186420/
MRI-1867
Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979564/
Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396529/
MT-178
Antinociceptive effects of the selective CB2 agonist MT178 in inflammatory and chronic rodent pain models (abst–2013) https://www.sciencedirect.com/science/article/pii/S0304395913000638
NABILONE/CESAMET
The Effects of Nabilone on Sleep in Fibromyalgia: Results of a Randomized Controlled Trial (full-2010) http://journals.lww.com/anesthesia-analgesia/Fulltext/2010/02000/The_Effects_of_Nabilone_on_Sleep_in_Fibromyalgia_.56.aspx
A randomized, double-blinded, crossover pilot study assessing the effect of nabilone on spasticity in persons with spinal cord injury. (full – 2010) http://www.archives-pmr.org/article/S0003-9993%2810%2900072-9/fulltext
Marijuana: Medical Applications, Recreational Use and Substance Abuse Disorders. (link to download – 2010) http://www.eurekaselect.com/85221/article
The abuse potential of the synthetic cannabinoid nabilone. (link to download – 2010) The abuse potential of the synthetic cannabinoid CESAMET® CII (nabilone) Capsules For Oral Administration. (archived drug label – 2010) http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=16800
An Open-Label Comparison of Nabilone and Gabapentin as Adjuvant Therapy or Monotherapy in the Management of Neuropathic Pain in Patients with Peripheral Neuropathy. (abst – 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=311
Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413845/
The Therapeutic Potential of Cannabis and Cannabinoids. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442177/
Endocannabinoids in nervous system health and disease: the big picture in a nutshell (full–2012) http://rstb.royalsocietypublishing.org/content/367/1607/3193.full
Subjective, cognitive and cardiovascular dose-effect profile of nabilone and dronabinol in marijuana smokers. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335956/
Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities (full–2012) http://rstb.royalsocietypublishing.org/content/367/1607/3353.full?sid=1569c370-cd5c-4358-89ff-857201f5e069
Clinical implications for cannabinoid use in the rheumatic diseases: potential for help or harm? (full – 2012) http://onlinelibrary.wiley.com/doi/10.1002/art.34522/full
CADTH Rapid Response Report: Cannabinoids for the treatment of post-traumatic stress disorder (download–2012) https://www.cadth.ca/cannabinoids-treatment-post-traumatic-stress-disorder-review-clinical-effectiveness-and-guidelines-1
Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22491047
An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo- controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22921260
Nabilone decreases marijuana withdrawal and a laboratory measure of marijuana relapse (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682150/
The use of cannabinoids in chronic pain. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736518/
Transdermal delivery of cannabidiol Patent 8435556. (full – 2013) https://www.google.com/patents/US8435556
The pharmacologic and clinical effects of medical cannabis (download–2013) https://www.theroc.us/researchlibrary/The%20Pharmacologic%20and%20Clinical%20Effects%20of%20Medical%20Cannabis.pdf
Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells. (click “aspetjournals” for download–2013) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Combined+antiproliferative+effects+of+the+aminoalkylindole+WIN55%2C212-2+and+radiation+in+breast+cancer+cells.+++++++++++++&btnG Synthetic cannabis: A comparison of patterns of use and effect profile with natural cannabis in a large global sample. (UK/ Australia) (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23291209
Using cannabinoids in pain and palliative care. (abst – 2013) https://www.magonlinelibrary.com/doi/10.12968/ijpn.2010.16.10.79211
Nabilone for Non-chemotherapy Associated Nausea and Weight Loss due to Medical Conditions: A Review of the Clinical Effectiveness and Guidelines [Internet] (full–2014) http://www.ncbi.nlm.nih.gov/books/NBK253668/toc/?report=reader
Medical marijuana for cancer. (full – 2014) http://onlinelibrary.wiley.com/doi/10.3322/caac.21260/full
Use of a Synthetic Cannabinoid in a Correctional Population for Posttraumatic Stress Disorder-Related Insomnia and Nightmares, Chronic Pain, Harm Reduction, and Other Indications: A Retrospective Evaluation. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165471/
Drug discovery strategies that focus on the endocannabinoid signaling system in psychiatric disease. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696509/
Medical marijuana: more questions than answers. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243838/
Early phytocannabinoid chemistry to endocannabinoids and beyond (Israel/ Scotland/ USA) (link to PDF– 2014) https://www.researchgate.net/publication/266945311_Early_phytocannabinoid_chemistry_to_endocannabinoids_and_beyond
Report on Medical Cannabis Research History- What the Science Says (USA) (article–2014) http://www.safeaccessnow.org/medical_cannabis_research_what_does_the_evidence_say
Nabilone as an Adjunctive to Gabapentin for Multiple Sclerosis-Induced Neuropathic Pain: A Randomized Controlled Trial. (Canada) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1111/pme.12569/full
Plant derived substances with anti-cancer activity: from folklore to practice. (Israel) (full – 2015) http://journal.frontiersin.org/article/10.3389/fpls.2015.00799/full
Emerging drugs of abuse: current perspectives on synthetic cannabinoids. (France) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622447/
Small Molecules from Nature Targeting G-Protein Coupled Cannabinoid Receptors: Potential Leads for Drug Discovery and Development. (United Arab Emirates/ India/ USA/Saudi Arabia) (full – 2015) http://www.hindawi.com/journals/ecam/2015/238482/
Prevalence and determinants of cannabinoid prescription for the management of chronic noncancer pain: a postal survey of physicians in the Abitibi-Témiscamingue region of Quebec. (Canada) (full – 2015) http://cmajopen.ca/content/3/2/E251.full?sid=139f05c1-b441-476b-99ff-addf8c918e1a
Sequelae of Cannabis as Medicine. (USA) (full – 2015) http://painmedicine.oxfordjournals.org/content/16/7/1447
Cannabis in the Treatment of Dystonia, Dyskinesias, and Tics. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604174/
Clinical perspectives on medical marijuana (cannabis) for neurologic disorders. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549715/
Efficacy, tolerability and safety of cannabinoid treatments in the rheumatic diseases: A systematic review of randomized controlled trials. (Canada/ Germany/ USA) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1002/acr.22727/full
Clinical Use of Cannabinoids for Symptom Control in Multiple Sclerosis. (UK) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604175/
Promising cannabinoid-based therapies for Parkinson’s disease: motor symptoms to neuroprotection. (Republic of Korea) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404240/
Investigational drugs under development for the treatment of PTSD. (USA) (link to PDF – 2015) https://www.researchgate.net/publication/273578445_Investigational_drugs_under_development_for_the_treatment_of_PTSD
The Effectiveness of Cannabinoids in the Management of Chronic Nonmalignant Neuropathic Pain: A Systematic Review. (USA/ Italy) (download – 2015) https://www.researchgate.net/publication/272406849_The_Effectiveness_of_Cannabinoids_in_the_Management_of_Chronic_Nonmalignant_Neuropathic_Pain_A_Systematic_Review
The efficacy of nabilone, a synthetic cannabinoid, in the treatment of PTSD-associated nightmares: A preliminary randomized, double-blind, placebo-controlled cross-over design study. (Canada) (summary – 2015) https://reachfamilies.umn.edu/research/document/7805 (abst – 2015) https://www.sciencedirect.com/science/article/pii/S0306453014004132
Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease. (Canada) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26271310
Endocannabinoid system: Role in depression, reward and pain control (Review). (China) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042796/
Effects of zolpidem alone and in combination with nabilone on cannabis withdrawal and a laboratory model of relapse in cannabis users. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302052/
Cannabinoids, inflammation, and fibrosis. (USA) (full – 2016) https://www.fasebj.org/doi/full/10.1096/fj.201600646R
Nabilone for the Management of Pain. (Canada) (full – 2016) https://accpjournals.onlinelibrary.wiley.com/doi/full/10.1002/phar.1709
ENDOCANNABINOID SYSTEM: A multi-facet therapeutic target (India) (link to PDF–2016) https://www.researchgate.net/publication/301533431_Endocannabinoid_System_A_Multi-Facet_Therapeutic_Target
Efficacy, tolerability and safety of cannabinoids for chronic neuropathic pain : A systematic review of randomized controlled studies. (Germany) (abst in English & German – 2016) http://link.springer.com/article/10.1007%2Fs00482-015-0089-y
The Use of Cannabis for Headache Disorders. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436334/
A Guide to the National Academy of Science Report on Cannabis: An Exclusive Discussion with Panel Members. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569624/
Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go? (Germany/ Austria) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388177/
The Use of Medical Cannabis with Other Medications: A Review of Safety and Guidelines [Internet]. (Canada) (full – 2017) https://www.ncbi.nlm.nih.gov/books/NBK470766/
Incretin Secretion in Humans is under the Influence of Cannabinoid Receptors. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625085/
Selective Cannabinoids for Chronic Neuropathic Pain: A Systematic Review and Meta- analysis. (Canada) (full – 2017) https://journals.lww.com/anesthesia-analgesia/Fulltext/2017/11000/Selective_Cannabinoids_for_Chronic_Neuropathic.32.aspx
Nabilone pharmacotherapy for cannabis dependence: A randomized, controlled pilot study. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699926/
Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. (Israel) (link to PDF – 2017) http://www.painphysicianjournal.com/linkout?issn=1533-3159&vol=20&page=E755
Cannabis, Cannabinoids, and Sleep: a Review of the Literature. (USA) (link to download – 2017) https://www.med.upenn.edu/cbti/assets/user-content/documents/s11920-017-0775-9.pdf
Current evidence of cannabinoid-based analgesia obtained in preclinical and human experimental settings. (Germany) (click “cedfoundation” for download – 2017) https://scholar.google.com/scholar?q=Current+evidence+of+cannabinoid-based+analgesia+obtained+in+preclinical+and+human+%09experimental+settings.&hl=en&as_sdt=0&as_vis=1&oi=scholart
A randomized-controlled trial of nabilone for the prevention of acute postoperative nausea and vomiting in elective surgery. (Canada) (abst in English & French – 2017) https://link.springer.com/article/10.1007%2Fs12630-017-0814-3
Cannabinoid Receptors in Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance. (Austria/ Germany) (abst – 2017) https://link.springer.com/chapter/10.1007%2F164_2016_105
Concise review of the management of iatrogenic emesis using cannabinoids: emphasis on nabilone for chemotherapy-induced nausea and vomiting. (USA) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28235999
Cannabinoids for nausea and vomiting related to chemotherapy: Overview of systematic reviews. (Brazil) (abst – 2017) https://onlinelibrary.wiley.com/doi/full/10.1002/ptr.5975
Cannabis for Pain and Headaches: Primer. (USA) (abst – 2017) https://link.springer.com/article/10.1007%2Fs11916-017-0619-7
https://www.semanticscholar.org/paper/Cannabis-for-Pain-and-Headaches%3A-Primer.-Kim-Fishman/bebc1e9df306be62c4332f218c91658f9cfc4ea2
An update on the advancements in the treatment of agitation in Alzheimer’s disease. (USA) (abst – 2017) https://www.tandfonline.com/doi/abs/10.1080/14656566.2017.1307340?journalCode=ieop20
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis. (Italy) (full – 2018) http://www.mdpi.com/2305-6320/5/3/91/htm
Cannabinoids for Behavioural Symptoms in Adults with Dementia: A Review of Clinical Effectiveness and Guidelines. (Spain/ USA) (full – 2018) https://www.ncbi.nlm.nih.gov/books/NBK526373/
Cannabis in palliative care: current challenges and practical recommendations. (Canada/ USA) (full – 2018) http://apm.amegroups.com/article/view/20097/21242
Erratum to cannabis in palliative care: current challenges and practical recommendations. (Canada/ USA) (erratum – 2018) http://apm.amegroups.com/article/view/23880/23545
Pharmaceutical cannabinoid use in Manitoba, 2004/05 to 2014/15: a population-based cross-sectional study. (Canada) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298870/
Management of Post-Traumatic Nightmares: a Review of Pharmacologic and Nonpharmacologic Treatments Since 2013 . (USA) (full – 2018) https://link.springer.com/article/10.1007%2Fs11920-018-0971-2
The effect of nabilone on appetite, nutritional status, and quality of life in lung cancer patients: a randomized, double-blind clinical trial (Mexico) (link to PDF–2018) https://www.researchgate.net/publication/323831708_The_effect_of_nabilone_on_appetite_nutritional_status_and_quality_of_life_in_lung_cancer_patients_a_randomized_double-blind_clinical_trial
Medical use of cannabis and cannabinoids containing products – Regulations in Europe and North America. (Israel) (abst– 2018) https://www.ejinme.com/article/S0953-6205(18)30001-3/fulltext
https://www.semanticscholar.org/paper/Medical-use-of-cannabis-and-cannabinoids-containing-Abuhasira-Shbiro/2adff3a9a89097f281582abc123c2744c5ac6db6
Safety and efficacy of nabilone for acute chemotherapy-induced vomiting prophylaxis in pediatric patients: A multicenter, retrospective review (Canada) (abst–2018) https://taomc.org/en/evidence-base/safety-and-efficacy-of-nabilone-for-acute-chemotherapy-induced-vomiting-prophylaxis-in-pediatric-patients-a-multicenter-retrospective-review
Varenicline and nabilone in tobacco and cannabis co-users: effects on tobacco abstinence, withdrawal and a laboratory model of cannabis relapse. (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/30378231
2019 Cannabis and Cannabinoids (PDQ®) Patient Version. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK65875/
2019 Cannabis and Cannabinoids (PDQ®)Health Professional Version. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK65755/
Medicinal use of cannabis based products and cannabinoids. (UK) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447998/
Nabilone administration in refractory chronic diarrhea: a case series. (Italy) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593541/
The use of cannabis in supportive care and treatment of brain tumor. (Austria) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655483/
Nabilone for the Treatment of Post-Traumatic Stress Disorder: A Review of Clinical Effectiveness and Guidelines. (Canada) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK546995/
Antiemetic Agents. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK548071/
Nabilone. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK547865/
Medical Cannabis for the Treatment of Dementia: A Review of Clinical Effectiveness and Guidelines [Internet]. (Canada) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK546328/
24S-Hydroxycholesterol Is Associated with Agitation Severity in Patients with Moderate- to-Severe Alzheimer’s Disease: Analyses from a Clinical Trial with Nabilone. (Canada) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839471/
Medical Cannabis Use in Palliative Care: Review of Clinical Effectiveness and Guidelines – An Update [Internet]. (Canada) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK551867/
Cannabis for pain in orthopedics: a systematic review focusing on study methodology (Canada/Netherlands/Spain) (link to PDF, full in English & abst in French – 2019) http://canjsurg.ca/62-6-001018/
Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders. (USA) (click “researchgate” for download – 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Potential+of+Cannabinoid+Receptor+Ligands+as+Treatment+for+Substance+Use+Disorders%22&btnG
Persistence of use of prescribed cannabinoid medicines in Manitoba, Canada: a population-based cohort study. (Canada) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31240747
Agitation, Oxidative Stress, and Cytokines in Alzheimer Disease: Biomarker Analyses From a Clinical Trial With Nabilone for Agitation. (Canada) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31547752
NESS0327
Docosahexaenoyl ethanolamide improves glucose uptake and alters endocannabinoid system gene expression in proliferating and differentiating C2C12 myoblasts. (full – 2014) http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00100/full
Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release. (Hungary/ USA/ Japan) (full – 2015) http://www.jneurosci.org/content/35/27/10039.full?sid=7e769d1b-9b77-42fe-92d0-8b337b34b9b6
Possible Therapeutic Doses of Cannabinoid Type 1 Receptor Antagonist Reverses Key Alterations in Fragile X Syndrome Mouse Model. (Spain) (full – 2016) http://www.mdpi.com/2073-4425/7/9/56/htm
Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice. (China/ USA/ Canada) (full – 2017) https://www.jci.org/articles/view/91038
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NESS06SM
Metabolic side effects induced by olanzapine treatment are neutralized by CB1 receptor antagonist compounds co-administration in female rats. (Italy) (abst – 2017) https://www.semanticscholar.org/paper/Metabolic-side-effects-induced-by-olanzapine-are-by-Lazzari-Serra/8a2e837c996b4c6ae703b5b96a6f212d51aee818
NIDA-41020
Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl- 2′-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice (Italy) (click “coreacuk” for download–2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Pharmacokinetic-pharmacodynamic+influence+of+N-
palmitoylethanolamine%2C+arachidonyl-2%E2%80%B2-chloroethylamide+and+WIN+55%2C212-2+on+the+anticonvulsant+activity+of+antiepileptic+drugs+against+audiogenic+seizures+in+DBA%2F2+mice%22&btnG
NM2201/BLACK MAMBA
Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of five novel synthetic cannabinoids in rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823726/
Lethal high: acute disseminated encephalomyelitis (ADEM) triggered by toxic effect of synthetic cannabinoid black mamba. (UK) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534782/
NMP-7
NMP-7 inhibits chronic inflammatory and neuropathic pain via block of Cav3.2 T-type calcium channels and activation of CB2 receptors. (full – 2014) https://journals.sagepub.com/doi/full/10.1186/1744-8069-10-77
NMP-181
Analgesic effect of a mixed T-type channel inhibitor/CB2 receptor agonist (full–2013) http://www.molecularpain.com/content/9/1/32
NST/NS TYR/N-STEAROYL-1-TYROSINE
N-stearoyltyrosine protects primary cortical neurons against Aβ(1-40)-induced injury through inhibiting endocannabinoid degradation. (China) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0024320515000521
N-stearoyltyrosine protects primary cortical neurons against oxygen-glucose deprivation- induced apoptosis through inhibiting anandamide inactivation system (China) (abst–2017) http://www.sciencedirect.com/science/article/pii/S0168010217300123
N-stearoyl-l-Tyrosine inhibits the cell senescence and apoptosis induced by H2O2 in HEK293/Tau cells via the CB2 receptor. (China) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0009279716307293
O-1602
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2. (full – 2010) http://pharmrev.aspetjournals.org/content/62/4/588.full
A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans (full–2011) http://joe.endocrinology-journals.org/content/211/2/177.long
Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126905/
The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116968/
A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst – 2011) https://www.ncbi.nlm.nih.gov/pubmed/21726355
The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. (abst – 2011) http://www.sciencedirect.com/science/article/pii/S0304394011008986 https://www.semanticscholar.org/paper/The-abnormal-cannabidiol-analogue-O-1602-reduces-in-Schuelert-McDougall/dbb5ef6050fcb0b1fbd5edefb1b5b10be75967d8
The novel cannabinoid receptor GPR55, inhibits cholangiocarcinoma growth (abst–2011) https://www.fasebj.org/doi/10.1096/fasebj.25.1_supplement.1117.3
GPR18 in microglia: implications for the CNS and endocannabinoid system signaling. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525861/
Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548934/
siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration. (full – 2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493281/
The atypical cannabinoid O-1602 shows antitumorigenic effects in colon cancer cells and reduces tumor growth in a colitis-associated colon cancer model. (link to download – 2012) http://www.biomedcentral.com/content/pdf/2050-6511-13-S1-A23.pdf
The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats. (abst – 2012) https://www.semanticscholar.org/paper/The-atypical-cannabinoid-O-1602-stimulates-food-and-D%C3%ADaz-Arteaga-V%C3%A1zquez/b8a4956afd14490d9daeb908da6b8bcc51316b32
The atypical cannabinoid O-1602 increases hind paw sensitisation in the chronic constriction injury model of neuropathic pain. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S0304394011016612
The Atypical Cannabinoid O-1602: Targets, Actions, and the Central Nervous System. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22831390
Evidence That A Functional Gpr18-based Signaling System In The Anterior Murine Eye Modulates Intraocular Pressure. (abst – 2012) http://iovs.arvojournals.org/article.aspx?articleid=2358806&resultClick=1
O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529923/
A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677091/
A GPR18-based signaling system regulates IOP in murine eye. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687663/
(R,R’)-4′-Methoxy-1-naphthylfenoterol Targets GPR55-mediated Ligand Internalization and Impairs Cancer Cell Motility. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935314/
Evaluation of the insulin releasing and antihyperglycaemic activities of GPR55 lipid agonists using clonal beta-cells, isolated pancreatic islets and mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949647/
Anticancer activity of anandamide in human cutaneous melanoma cells. (link to download – 2013) https://europepmc.org/article/med/24041928
Role of endogenous cannabinoid system in the gut. (link to download – 2013) http://www.actaps.com.cn/qikan/manage/wenzhang/2013-4-12.pdf
Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice. (click “uni-meunchen” for download – 2013) https://scholar.google.com/scholar?q=Anti-inflammatory+role+of+cannabidiol+and+O-1602+in+cerulein-induced+acute+pancreatitis+in+mice.&hl=en&as_sdt=0&as_vis=1&oi=scholart Cyclooxygenase-2 regulates anandamide-induced endoplasmic reticulum stress in tumorigenic keratinocytes. (abst – 2013) http://cancerres.aacrjournals.org/content/73/8_Supplement/2128
(R,R’)-4’-methoxy- 1-naphthylfenoterol Inhibits GPR55 signaling and the modulation of motility in human cancer cells. (abst – 2013) http://cancerres.aacrjournals.org/content/73/8_Supplement/5516.short
Cannabinoid Effects on β Amyloid Fibril and Aggregate Formation, Neuronal and Microglial-Activated Neurotoxicity In Vitro (abst–2013) https://www.semanticscholar.org/paper/Cannabinoid-Effects-on-%CE%B2-Amyloid-Fibril-and-and-In-Janefjord-Maag/641ebdd551d8ae69283c3ace38d72755e8d957eb Increase of mesenchymal stem cell migration by Cannabidiol via activation of p42/44 MAPK. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S0006295213007478
Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1 receptors. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243853/
Activation of GPR18 by Cannabinoid compounds: A tale of biased agonism (full–2014) http://onlinelibrary.wiley.com/doi/10.1111/bph.12746/full
The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells. (full – 2014) https://academic.oup.com/intimm/article-lookup/doi/10.1093/intimm/dxu097
Activation of GPR55 Receptors Exacerbates oxLDL-Induced Lipid Accumulation and Inflammatory Responses, while Reducing Cholesterol Efflux from Human Macrophages. (Italy) (full – 2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126839
Pharmacological profiling of the hemodynamic effects of cannabinoid ligands: a combined in vitro and in vivo approach. (UK/ Sweden) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492759/
Mechanisms of vasorelaxation induced by the cannabidiol analogue compound O-1602 in the rat small mesenteric artery. (Oman/ UK) (link to PDF–2015) https://www.researchgate.net/publication/281166628_Mechanisms_of_vasorelaxation_induced_by_the_cannabidiol_analogue_compound_O-1602_in_the_rat_small_mesenteric_artery
Central administration of GPR55 receptor agonist and antagonist modulates anxiety- related behaviors in rats. (Iran) (abst – 2015) https://www.semanticscholar.org/paper/Central-administration-of-GPR55-receptor-agonist-in-Rahimi-Moghaddam/d056ca05ce2ef0ba0853de4606aa3e14c356e50c GPR55-dependent stimulation of insulin secretion from isolated mouse and human islets of Langerhans. (UK) (link to download – 2016) https://kclpure.kcl.ac.uk/portal/files/58649551/Liu_et_al_2016_Diabetes_Obesity_and_Metabolism.pdf
The effect of O-1602, an atypical cannabinoid, on morphine-induced conditioned place preference and physical dependence. (Iran) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/26971034
The novel cannabinoid receptor GPR55 mediates anxiolytic-like effects in the medial orbital cortex of mice with acute stress. (China) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553743/
Decisive role of P42/44 mitogen-activated protein kinase in Δ9-tetrahydrocannabinol- induced migration of human mesenchymal stem cells. (Germany) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739695/
Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis. (USA) (full – 2018) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14387
Novel protective effect of O-1602 and abnormal cannabidiol, GPR55 agonists, on ER stress-induced apoptosis in pancreatic β-cells. (China) (full – 2019) https://www.sciencedirect.com/science/article/pii/S0753332218375668?via%3Dihub
Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer. (Canada) (full – 2019) https://www.frontiersin.org/articles/10.3389/fphar.2019.01124/full
Effects of O-1602 and CBD on TNBS-induced colonic disturbances. (China) (abst – 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/nmo.13756
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O-1663
β-adrenergic Antagonists, Carbonic Anhydrase Inhibitors And α2-agonists Reduce The Effects Of Cannabinoids In A Rat Glaucoma Model. (abst – 2011) http://iovs.arvojournals.org/article.aspx?articleid=2360875&resultClick=1
O-1918
Abnormal-Cannabidiol-Induced Increase in Aqueous Humor Outflow. (abst – 2010) http://iovs.arvojournals.org/article.aspx?articleid=2368788&resultClick=1
Involvement of a non-CB1/CB2 cannabinoid receptor in the aqueous humor outflow- enhancing effects of abnormal-cannabidiol. (full – 2012) https://www.academia.edu/4595529/Involvement_of_a_non-CB1_CB2_cannabinoid_receptor_in_the_aqueous_humor_outflow-enhancing_effects_of_abnormal-cannabidiol
Effect of Oleoylethanolamide on Aqueous Humor Outflow. (abst – 2012) http://iovs.arvojournals.org/article.aspx?articleid=2352002&resultClick=1
Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery. (abst – 2012) https://www.semanticscholar.org/paper/Endothelium-dependent-mechanisms-of-the-effect-of-Baranowska-Kuczko-Maclean/6a1726529a5444318b14fa889546050a8f529a0c
A GPR18-based signaling system regulates IOP in murine eye. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687663/
Mechanisms of vasorelaxation induced by oleoylethanolamide in the rat small mesenteric artery. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23340219
Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984660/
Vascular targets for cannabinoids: animal and human studies. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954478/
Activation of GPR18 by Cannabinoid compounds: A tale of biased agonism. (full – 2014) http://onlinelibrary.wiley.com/doi/10.1111/bph.12746/full
Neuronal Nitric Oxide Synthase Dependent Elevation in Adiponectin in the Rostral Ventrolateral Medulla Underlies GPR18-mediated Hypotension in Conscious Rats. (link to PDF – 2014) http://jpet.aspetjournals.org/content/early/2014/08/06/jpet.114.216036.long
A role for GPR55 in human placental venous endothelial cells. (Austria) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487816/
The GPR55 agonist lysophosphatidylinositol mediates vasorelaxation of the rat mesenteric resistance artery and induces calcium release in rat mesenteric artery endothelial cells. (UK/ Oman) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459022/
Mechanisms of vasorelaxation induced by the cannabidiol analogue compound O-1602 in the rat small mesenteric artery. (Oman/ UK) (link to PDF– 2015) https://www.researchgate.net/publication/281166628_Mechanisms_of_vasorelaxation_induced_by_the_cannabidiol_analogue_compound_O-1602_in_the_rat_small_mesenteric_artery
Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment. (Canada/ Poland/ Germany) (full – 2016) http://journal-inflammation.biomedcentral.com/articles/10.1186/s12950-016-0129-0
The endocannabinoid anandamide causes endothelium-dependent vasorelaxation in human mesenteric arteries. (UK) (full – 2016) http://www.sciencedirect.com/science/article/pii/S104366181630113X
Evidence for a GPR18 Role in Diurnal Regulation of Intraocular Pressure (USA) (full–2016) http://iovs.arvojournals.org/article.aspx?articleid=2588572
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The Effect of Chronic Activation of the Novel Endocannabinoid Receptor GPR18 on Myocardial Function and Blood Pressure in Conscious Rats. (USA/ Egypt) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209303/
Endocannabinoids inhibit neurogenic inflammation in murine joints by a non-canonical cannabinoid receptor mechanism. (Canada) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S0143417916300476
Cannabinoids Regulate the Diameter of Pericyte-Containing Retinal Capillaries in Rats. (China) (full – 2017) https://www.karger.com/Article/FullText/484193
Mechanisms of l-alpha-lysophosphatidylinositol-induced relaxation in human pulmonary arteries. (Poland) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0024320517305982?via%3Dihub
https://www.semanticscholar.org/paper/Mechanisms-of-relaxation-in-human-pulmonary-Karpi%C5%84ska-Baranowska-Kuczko/4eca663f2e6f254bb3da58b23f12655404644993
Direct activation of Ca2+ and voltage-gated potassium channels of large conductance by anandamide in endothelial cells does not support the presence of endothelial atypical cannabinoid receptor. (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28327344
Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures. (Germany/ USA) (full – 2019) https://www.mdpi.com/1422-0067/20/6/1266/htm
Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea. (USA/ Taiwan) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30969262
O-1966
Modulation of inflammatory responses by a cannabinoid-2-selective agonist after spinal cord injury. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235339/
Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a model of traumatic brain injury (link to PDF–2011) https://www.researchgate.net/publication/49846733_Acute_Effects_of_a_Selective_Cannabinoid-2_Receptor_Agonist_on_Neuroinflammation_in_a_Model_of_Traumatic_Brain_Injury_
Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325902/
A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22903455
Using the endocannabinoid system as a neuroprotective strategy in perinatal hypoxic- ischemic brain injury. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146074/
O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529923/
Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629438/
Effect of cannabinoid CB2 receptor agonism on learning and memory in a mouse model of photothrombosis. (abst – 2013) https://www.fasebj.org/doi/10.1096/fasebj.27.1_supplement.1097.4
Cannabinoid receptor type-2 stimulation, blockade, and deletion alters the vascular inflammatory responses to traumatic brain injury. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248435/
A CB2-Selective Cannabinoid Suppresses T-Cell Activities and Increases Tregs and IL- 10. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528965/
A selective cannabinoid CB2 agonist attenuates damage and improves memory retention following stroke in mice. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552583/
Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders. (Spain/ USA) (full – 2016) http://journal.frontiersin.org/article/10.3389/fnins.2016.00406/full
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O-2050
Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences. (full – 2012) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038609
Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors. (full – 2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438986/
Structural analogs of pyrazole and sulfonamide cannabinoids: Effects on acute food intake in mice. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586205/
The complex effects of cannabinoids on insulin secretion from rat isolated islets of Langerhans. (abst – 2013) https://www.semanticscholar.org/paper/The-complex-effects-of-cannabinoids-on-insulin-from-Anderson-Randall/3bf96844fdd3e09c7123c8a61f71ec5784759dc5
O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus. (click “unibonn” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=O-
2050+facilitates+noradrenaline+release+and+increases+the+CB1+receptor+inverse+agonistic+effect+of+rimonabant+in+the+guinea +pig+hippocampus.&btnG
Biased Agonism of Three Different Cannabinoid Receptor Agonists in Mouse Brain Cortex. (Spain/ Colombia) (full – 2016) http://journal.frontiersin.org/article/10.3389/fphar.2016.00415/full
Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin. (Portugal/ USA) (link to PDF – 2016) https://www.researchgate.net/publication/303358549_Hierarchical_glucocorticoid-
endocannabinoid_interplay_regulates_the_activation_of_the_nucleus_accumbens_by_insulin
Cannabinoid receptors and TRPA1 on neuroprotection in a model of retinal ischemia. (Brazil) (download – 2016) http://innt.org.br/wp-content/uploads/2017/07/Receptores-canabino%CC%81ides-e-TRPA1-em-neuroprotec%CC%A7a%CC%83o-em-um-modelo-de-isquemia-da-retina.pdf
Control of myogenic tone and agonist induced contraction of intramural coronary resistance arterioles by cannabinoid type 1 receptors and endocannabinoids (Hungary) (full–2017) http://www.sciencedirect.com/science/article/pii/S1098882317300047
O-2545
Cannabinoid agonists rearrange synaptic vesicles at excitatory synapses and depress motoneuron activity in vivo (abst–2015) http://www.sciencedirect.com/science/article/pii/S0028390815000076
Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans. (USA) (full – 2016) http://www.g3journal.org/content/early/2016/04/11/g3.116.026997.long
O-7460
A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2- arachidonoylglycerol with potential anti-obesity effects. (full – 2013) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687659/
CB1 Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal. (Spain/ Italy/ France) (download – 2016) https://repositori.upf.edu/bitstream/handle/10230/30842/Saravia_BioPsy_CB1.pdf?sequence=1&isAllowed=y
OCTADECYLPROPYL SULFAMIDE
Octadecylpropyl Sulfamide Reduces Neurodegeneration and Restores the Memory Deficits Induced by Hypoxia-Ischemia in Mice. (Spain) (full – 2018) https://www.frontiersin.org/articles/10.3389/fphar.2018.00376/full
OL-135
Endocannabinoid System: the Direct and Indirect Involvement in the Memory and Learning Processes—a Short Review. (Poland) (full – 2016) http://link.springer.com/article/10.1007%2Fs12035
OLIVE OIL
Extravirgin olive oil up-regulates CB1 tumor suppressor gene in human colon cancer cells and in rat colon via epigenetic mechanisms. (abst – 2014) https://www.semanticscholar.org/paper/Extravirgin-olive-oil-up-regulates-CB%E2%82%81-tumor-gene-Francesco-Falconi/cf0b4ac7e3b84aa44beb7b396664d31edd1ff44a
Small Molecules from Nature Targeting G-Protein Coupled Cannabinoid Receptors: Potential Leads for Drug Discovery and Development (United Arab Emirates/India/USA/Saudi Arabia) (full–2015) http://www.hindawi.com/journals/ecam/2015/238482/
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice. (Italy) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166557/
Dietary ω-3 Polyunsaturated Fatty Acids Inhibit Tumor Growth in Transgenic ApcMin/+ Mice, Correlating with CB1 Receptor Up-Regulation. (Italy) (full – 2017) http://www.mdpi.com/1422-0067/18/3/485/htm
Extraction Method and Analysis of Cannabinoids in Cannabis Olive Oil Preparations. (Italy) (download – 2017) https://air.unimi.it/retrieve/handle/2434/544430/945698/Cannabis%20planta%20medica.pdf
Cannabinoids concentration variability in cannabis olive oil galenic preparations. (Italy) (click “Open Access” then “Wiley” for download – 2017) https://www.semanticscholar.org/paper/Cannabinoids-concentration-variability-in-cannabis-Carcieri-Tomasello/8010d3c7f6e5efaf339af7ec2850ea4748be7679 Therapeutic use of Δ9-THC and cannabidiol: evaluation of a new extraction procedure for the preparation of cannabis-based olive oil. (Italy) (abst – 2017) http://www.eurekaselect.com/157854/article
Untargeted rat brain metabolomics after oral administration of a single high dose of cannabidiol. (Italy/ Switzerland) (link to PDF – 2018) https://www.researchgate.net/publication/326980274_Untargeted_rat_brain_metabolomics_after_oral_administration_of_a_single_high_dose_of_cannabidiol
OMDM-1
Therapeutic Opportunities through the Modulation of Endocannabinoid Transport. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255948/
For whom the endocannabinoid tolls: Modulation of innate immune function and implications for psychiatric disorders (Ireland) (click “academia” for download–2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=For+whom+the+endocannabinoid+tolls%3A+Modulation+of+innate+immune+function+and+implications+for+psychiatric+disorders.&btnG
The cannabinoid transporter inhibitor OMDM-2 reduces social interaction: Further evidence for transporter-mediated endocannabinoid release. (USA) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S002839081730549X?via%3Dihub
https://www.semanticscholar.org/paper/The-cannabinoid-transporter-inhibitor-OMDM-2-social-Seillier-Giuffrida/5634701cbf2c7bfc863575d6d7b68c9b1cba4faf
OMDM-2
Activity-based anorexia in C57/BL6 mice : effects of the phytocannabinoid, Delta9- tetrahydrocannabinol (THC) and the anandamide analogue, OMDM-2 (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20471226
Therapeutic Opportunities through the Modulation of Endocannabinoid Transport. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255948/
Curcumin sensitizes human U-87 glioblastoma and MCF-7 breast cancer cells to the endocannabinoid reuptake inhibitor OMDM-2. (Germany) (link to PDF – 2015) https://www.researchgate.net/publication/321260008_Curcumin_synergizes_with_the_endocannabinoid_reuptake_inhibitor_OMDM- 2_in_human_MCF-7_breast_cancer_and_U-87_glioblastoma_cells
The administration of endocannabinoid uptake inhibitors OMDM-2 or VDM-11 promotes sleep and decreases extracellular levels of dopamine in rats (click “researchgate” for download–2013) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=The+administration+of+endocannabinoid+uptake+inhibitors+OMDM-2+or+VDM-11+promotes+sleep+and+decreases+extracellular+levels+of+dopamine+in+rats.++++++&btnG
For whom the endocannabinoid tolls: Modulation of innate immune function and implications for psychiatric disorders (Ireland) (click “academia” for download–2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=For+whom+the+endocannabinoid+tolls%3A+Modulation+of+innate+immune+function+and+implications+for+psychiatric+disorders.&btnG
OMDM-188
Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity. (Italy/ Canada) (full – 2019) https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1671-5
ORG-27569
Parameterization of Org27569: An allosteric modulator of the cannabinoid CB(1) G protein-coupled receptor. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145811/
Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation. (full – 2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320953/
A key agonist-induced conformational change in the cannabinoid receptor CB1 is blocked by the allosteric ligand Org 27569. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460482/
Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor one (CB1). (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617280/
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Real-time characterisation of Cannabinoid Receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799602/
Manual for use by national drug analysis laboratories Recommended methods for the Identification and Analysis of Synthetic Cannabinoid Receptor Agonists in Seized Materials (link to download–2013) http://www.unodc.org/documents/scientific/STNAR48_Synthetic_Cannabinoids_ENG.pdf
Behavioral effects of the cannabinoid CB1 receptor allosteric modulator ORG27569 in rats. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186448/
In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042670/
Optimization of Chemical Functionalities of Indole-2-Carboxamides to Improve Allosteric Parameters for the Cannabinoid Receptor 1 (CB1). (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203403/
Effects of the cannabinoid CB1 receptor allosteric modulator ORG 27569 on reinstatement of cocaine- and methamphetamine-seeking behavior in rats. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161648/
Allosteric Modulation of a Cannabinoid G Protein-coupled Receptor BINDING SITE ELUCIDATION AND RELATIONSHIP TO G PROTEIN SIGNALING. (full – 2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937654/
Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments. (Italy) (full – 2015) http://www.nature.com/articles/srep15453
Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor. (Australia/ New Zealand) (full – 2015) http://molpharm.aspetjournals.org/content/88/2/368.long
CB1 allosteric modulator Org27569 is an antagonist/inverse agonist of ERK1/2 signaling. (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484173/
Analysis of Natural Product Regulation of Cannabinoid Receptors in the treatment of Human Disease. (USA/ Jamaica) (click “researchgate” for download – 2017) https://scholar.google.com/scholar?q=Analysis+of+natural+product+regulation+of+cannabinoid+receptors+in+the+treatment+of+human+disease.&hl=en&as_sdt=0&as_vis=1&oi=scholart Structure of an allosteric modulator bound to the CB1 cannabinoid receptor (USA/China) (abst–2019) https://www.nature.com/articles/s41589-019-0387-2
PB-22/QUPIC/ ‘CRAZY MONKEY’/’PSYCLONE’ and DERIVATIVES
‘Crazy Monkey’ Poisons Man and Dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid. (link to PDF – 2014) https://www.researchgate.net/publication/262930652_’Crazy_Monkey’_Poisons_Man_and_Dog_Human_and_canine_seizures_due_to_PB-22_a_novel_synthetic_cannabinoid
Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497846/
Schedules of Controlled Substances: Extension of Temporary Placement of PB-22, 5F- PB-22, AB-FUBINACA and ADB-PINACA in Schedule I of the Controlled Substances Act. final order. (full – 2015) https://www.federalregister.gov/documents/2016/02/05/2016-02308/schedules-of-controlled-substances-extension-of-temporary-placement-of-pb-22-5f-pb-22-ab-fubinaca
Deaths linked to synthetic cannabinoids. (Australia) (link to PDF – 2015) https://www.researchgate.net/publication/273639870_Deaths_linked_to_synthetic_cannabinoids
The effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135. (click “academia” for download – 2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=The+effects+of+bioisosteric+fluorine+in+synthetic+cannabinoid+designer+drugs+JWH-018%2C+AM-2201%2C+UR-144%2C+XLR-11%2C+PB-22%2C+5F-PB-22%2C+APICA%2C+and+STS- 135.+++++++&btnG
Psyclones: a roller coaster of life? Hidden synthetic cannabinoids and stimulants in apparently harmless products. (abst – 2015) https://www.semanticscholar.org/paper/Psyclones%3A-a-roller-coaster-of-life-Hidden-and-in-Santacroce-Corazza/6fdb82b6a8c505260068954f88696579d52066bd Native CB1 receptor affinity, intrisic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135 (abst–2015) http://www.sciencedirect.com/science/article/pii/S0028390815301817
Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation. (UK) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135680/
Synthetic Cannabinoid Abuse Resulting in ST-Segment Elevation Myocardial Infarction Requiring Percutaneous Coronary Intervention. (USA) (click “PDF Reader” for full – 2016) https://kundoc.com/pdf-synthetic-cannabinoid-abuse-resulting-in-st-segment-elevation-myocardial-infarct.html
Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons. (Canada) (link to PDF– 2016) https://www.researchgate.net/publication/303713782_Pharmacological_characterization_of_emerging_synthetic_cannabinoids_in_HEK293T_cells_and_hippocampal_neurons
Simultaneous detection of 93 synthetic cannabinoids by liquid chromatography-tandem mass spectrometry and retrospective application to real forensic samples. (Germany) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27400642
Identification and quantification of synthetic cannabinoids in “spice-like” herbal mixtures: update of the German situation for the spring of 2015. (abst – 2016) http://link.springer.com/article/10.1007/s11419-015-0292-7 https://www.semanticscholar.org/paper/Identification-and-quantification-of-synthetic-in-a-Langer-Lindigkeit/8b010e2a3b08be81ff2159bf139e9e29f72889b1 Analytical differentiation of quinolinyl- and isoquinolinyl-substituted 1-(5-fluoropentyl)- 1H-indole-3-carboxylates: 5F-PB-22 and its ten isomers. (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215287/
Motor vehicle collisions caused by the ‘super-strength’ synthetic cannabinoids, MAM- 2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014. (Japan) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486620/
Oral fluid vs. Urine Analysis to Monitor Synthetic Cannabinoids and Classic Drugs Recent Exposure. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931376/
Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of five novel synthetic cannabinoids in rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823726/
Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. (USA/ Australia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363769/
Metabolic Profile of Synthetic Cannabinoids 5F-PB-22, PB-22, XLR-11 and UR-144 by Cunninghamella elegans. (Australia) (click “utseduau” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Metabolic+Profile+of+Synthetic+Cannabinoids+5F-PB-22%2C+PB-22%2C+XLR-11+and+UR-144+by+%09Cunninghamella+elegans.&btnG Teens and Spice: A Review of Adolescent Fatalities Associated with Synthetic Cannabinoid Use. (USA/ Canada/ UK) (Click “researchgate” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Teens+and+Spice%3A+A+Review+of+Adolescent+Fatalities+Associated+with+Synthetic+Cannabinoid+Use.+%22&btnG
New-Onset Refractory Status Epilepticus Associated With the Use of Synthetic st Cannabinoids. (USA) (1 page – 2017) http://www.psychosomaticsjournal.com/article/S0033-3182(16)30124-4/fulltext
AB-CHMINACA-induced sudden death from non-cardiogenic pulmonary edema. (Japan) (abst – 2017) https://www.semanticscholar.org/paper/AB-CHMINACA-induced-sudden-death-from-pulmonary-Maeda-Kikura-Hanajiri/e73fbbbb944c987d9d6e5d27416783c9e87fcffa
Three fatalities associated with the synthetic cannabinoids 5F-ADB, 5F-PB-22, and AB- CHMINACA. (Germany) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S037907381730453X
Analytical confirmation of synthetic cannabinoids in a cohort of 179 presentations with acute recreational drug toxicity to an Emergency Department in London, UK in the first half of 2015. (UK/ Belgium) (abst – 2017) https://www.semanticscholar.org/paper/Analytical-confirmation-of-synthetic-cannabinoids-a-Abouchedid-Hudson/43414db17daf86cd4644238f6de9e27ea06f3ffe Retrospective Chart Review of Synthetic Cannabinoid Intoxication with Toxicologic Analysis. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942026/
Functional effects of synthetic cannabinoids versus Δ9 -THC in mice on body temperature, nociceptive threshold, anxiety, cognition, locomotor/exploratory parameters and depression. (Israel) (abst – 2018) https://www.semanticscholar.org/paper/Functional-effects-of-synthetic-cannabinoids-versus-Schreiber-Bader/bdcc732eca01fb98bf65981d65180ad3c9839dd5 Synthetic cannabinoids: Variety is definitely not the spice of life. (UK) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S1752928X1830355X
PF-622
Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation (USA) (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096949/
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PF-3845
Inhibition of monoacylglycerol lipase (MAGL) attenuates NSAID-induced gastric hemorrhages in mice. (full – 2011) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164340/
The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423256/
The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717616/
Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Anti- Withdrawal Effects in Morphine-Dependent Mice. (full – 2013) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629394/
Selective inhibition of FAAH produces antidiarrheal and antinociceptive effect mediated by endocannabinoids and cannabinoid-like fatty acid amides. (full – 2014) http://onlinelibrary.wiley.com/doi/10.1111/nmo.12272/full
The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437642/
Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110679/
Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy. (full – 2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457709/
Delta-9 tetrahydrocannabinol (THC) and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation (ICSS) in mice. (link to PDF – 2014) http://jpet.aspetjournals.org/content/early/2014/11/14/jpet.114.218677.long
Toward modulation of the endocannabinoid system for treatment of gastrointestinal disease: FAAHster but not “higher” (abst – 2014) http://onlinelibrary.wiley.com/doi/10.1111/nmo.12329/full
Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice. (USA) (full – 2015) http://jpet.aspetjournals.org/content/354/2/111.full
Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release. (Hungary/ USA/ Japan) (full – 2015) http://www.jneurosci.org/content/35/27/10039.full?sid=7e769d1b-9b77-42fe-92d0-8b337b34b9b6
Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477849/
Simultaneous inhibition of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) shares discriminative stimulus effects with ∆9-THC in mice. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407717/
Interference with acute nausea and anticipatory nausea in rats by fatty acid amide hydrolase (FAAH) inhibition through a PPARα and CB1 receptor mechanism, respectively: a double dissociation. (Canada/ USA) (abst – 2015) https://www.semanticscholar.org/paper/Interference-with-acute-nausea-and-anticipatory-in-Rock-Limebeer/3c3222856ef09080a317239ed423343ae28530c3
Effect of Pharmacological Modulation of the Endocannabinoid System on Opiate Withdrawal: A Review of the Preclinical Animal Literature. (Canada) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923145/
Elevation of 2-AG by monoacylglycerol lipase inhibition in the visceral insular cortex interferes with anticipatory nausea in a rat model. (Canada/ USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793281/
Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959103/
Cannabinoid Receptor Interacting Protein (CRIP1a) suppresses agonist-driven CB1 receptor internalization, and regulates receptor replenishment in an agonist-biased manner. (link to download – 2016) Cannabinoid Receptor Interacting Protein (CRIP1a) suppresses agonist-driven CB1 receptor internalization, and regulates receptor replenishment in an agonist-biased manner
Systemic and spinal administration of FAAH, MAGL inhibitors and dual FAAH/MAGL inhibitors produce antipruritic effect in mice. (Turkey) (abst – 2016) https://www.semanticscholar.org/paper/Systemic-and-spinal-administration-of-FAAH%2C-MAGL-in-Yesilyurt-%C3%87ayirli/99b308937fdb9bf5533c5168964a4a6d4a17f39e
The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain. (Poland/ Italy) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S1043661816305667
Pharmacological inhibition of fatty acid amide hydrolase attenuates social behavioural deficits in male rats prenatally exposed to valproic acid. (Ireland) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S1043661816308660
Fatty acid amide hydrolase inhibitors produce rapid anti-anxiety responses through amygdala long-term depression in male rodents. (Canada/ China) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487270/
Fatty acid amide hydrolase (FAAH) inhibitor PF-3845 reduces viability, migration and invasiveness of human colon adenocarcinoma Colo-205 cell line: an in vitro study. (Poland) (full – 2017) https://ojs.ptbioch.edu.pl/index.php/abp/article/view/1520/1189
Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771234/
Modulation of the endocannabinoid system by the fatty acid amide hydrolase, monoacylglycerol and diacylglycerol lipase inhibitors as an attractive target for secretory diarrhoea therapy. (Poland) (link to download – 2017) https://pdfs.semanticscholar.org/8cbc/d37ed15c77e65367d2cbf4be938317ef138d.pdf
FAAH Inhibition Produces Antidepressant-like efforts of Mice to Acute Stress via Synaptic Long-term Depression. (Canada/ China) (abst – 2017) https://www.semanticscholar.org/paper/FAAH-inhibition-produces-antidepressant-like-of-to-Wang-Zhang/96fbdee29bffa8d030b4d8f8e386d4b059ba69c4 Pharmacological inhibition of FAAH modulates TLR-induced neuroinflammation, but not sickness behaviour: An effect partially mediated by central TRPV1. (Ireland) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0889159117300594?via%3Dihub
Contrasting effects of selective MAGL and FAAH inhibition on dopamine depletion and GDNF expression in a chronic MPTP mouse model of Parkinson’s disease. (Germany) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0197018617301687
https://www.semanticscholar.org/paper/Contrasting-effects-of-selective-MAGL-and-FAAH-on-a-Pasquarelli-Porazik/d58b5b21b422a2ac852cfe10e5c78b2fc0a7f46b
N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation. (Belgium/ USA) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S138819811730001X
https://www.semanticscholar.org/paper/N-acylethanolamine-hydrolyzing-acid-amidase-and-and-Alhouayek-Bottemanne/673a30357e3fb87678dd19f913a2af0f41fa6708
Therapeutic endocannabinoid augmentation for mood and anxiety disorders: comparative profiling of FAAH, MAGL and dual inhibitors (USA/Denmark) (full–2018) https://www.nature.com/articles/s41398-018-0141-7
Inhibition of fatty acid amide hydrolase by PF-3845 alleviates the nitrergic and proinflammatory response in rat hippocampus following acute stress (Australia/UK) (full–2018) https://academic.oup.com/ijnp/advance-article/doi/10.1093/ijnp/pyy033/4951485
Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. (USA/ Japan) (full – 2018) https://www.sciencedirect.com/science/article/pii/S0028390818305082
MODULATION OF MEAN ARTERIAL PRESSURE AND DIURESIS BY RENOMEDULLARY INFUSION OF A SELECTIVE INHIBITOR OF FATTY ACID AMIDE HYDROLASE. (USA) (full – 2018) https://www.physiology.org/doi/full/10.1152/ajprenal.00090.2018?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org Inhibitory Control Deficits Associated with Upregulation of CB1R in the HIV-1 Tat Transgenic Mouse Model of Hand. (USA/ Japan) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898753/
top
PF-04457845
Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738192/
Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain (full–2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126636/
A Systems Pharmacology Perspective on the Clinical Development of Fatty Acid Amide Hydrolase Inhibitors for Pain. (full – 2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910012/
2012 Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective. (USA) (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064474/
The FAAH inhibitor PF-04457845 has THC-like rewarding and reinstatement effects in squirrel monkeys and increases dopamine levels in the nucleus accumbens shell in rats. (abst – 2014) https://www.fasebj.org/doi/10.1096/fasebj.28.1_supplement.838.6
Blocking of fatty acid amide hydrolase activity with PF-04457845 in human brain: a positron emission tomography study with the novel radioligand [11C]CURB (Canada/ USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635238/
Efficacy, tolerability and safety of cannabinoid treatments in the rheumatic diseases: A systematic review of randomized controlled trials. (Canada/ Germany/ USA) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1002/acr.22727/full
Fatty acid amide hydrolase inhibitors: a patent review (2009 – 2014). (Italy) (full – 2015) http://www.tandfonline.com/doi/full/10.1517/13543776.2015.1067683
Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats. (USA/ Italy) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846548/
Deficient adolescent social behavior following early-life inflammation is ameliorated by augmentation of anandamide signaling. (Canada/ USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461973/
The endocannabinoid system in pain and inflammation: Its relevance to rheumatic disease. (Australia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685274/
Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474. (Netherlands/ Italy/ USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641481/
Inhibition of Endocannabinoid-Metabolizing Enzymes in Peripheral Tissues Following Developmental Chlorpyrifos Exposure in Rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585048/
Efficacy and safety of a fatty acid amide hydrolase inhibitor (PF-04457845) in the treatment of cannabis withdrawal and dependence in men: a double-blind, placebo- controlled, parallel group, phase 2a single-site randomised controlled trial. (USA) (abst – 2018) https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(18)30427-9/fulltext
Different Routes to Inhibit Fatty Acid Amide Hydrolase: Do All Roads Lead to the Same Place? (Italy) (full – 2019) https://www.mdpi.com/1422-0067/20/18/4503/htm
Elevated Anandamide, Enhanced Recall of Fear Extinction, and Attenuated Stress Responses Following Inhibition of Fatty Acid Amide Hydrolase: A Randomized, Controlled Experimental Medicine Trial. (Sweden/ Canada) (full – 2019) https://www.biologicalpsychiatryjournal.com/article/S0006-3223(19)31589-6/fulltext
Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders (USA) (click “researchgate” for download – 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Potential+of+Cannabinoid+Receptor+Ligands+as+Treatment+for+Substance+Use+Disorders%22&btnG
Inhibition of fatty acid amide hydrolase by chlorpyrifos in juvenile rats results in altered exploratory and social behavior as adolescents (USA) (abst–2020) https://www.sciencedirect.com/science/article/abs/pii/S0161813X20300103
PGN-33
Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer’s Disease (Spain) (abst–2018) https://link.springer.com/article/10.1007%2Fs40263-018-0515-7
1-PHENYLISATIN
Pharmacological benefits of selective modulation of cannabinoid receptor type 2 (CB2) in experimental Alzheimer’s disease. (India) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0091305715300952
Selective modulator of cannabinoid receptor type 2 (CB2) against biochemical alterations and brain damage in chronic cerebral hypoperfusion induced vascular dementia. (India) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27599483
PHTHALATES
The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro. (abst – 2011) http://www.sciencedirect.com/science/article/pii/S0197018611002269
Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure (link to PDF–2012) https://www.researchgate.net/publication/229160116_Acetaminophen_pesticide_and_diethylhexyl_phthalate_metabolites_anandamide_and_fatty_acids_in_deciduous_molars_Potential_biomarkers_of_perinatal_exposure
Dose-specific effects of Di-isononyl phthalate on the endocannabinoid system and on liver of female zebrafish (Italy/Canada) (full–2017) https://academic.oup.com/endo/article/158/10/3462/4080744
Endocrine disruptors in the diet of male Sparus aurata: Modulation of the endocannabinoid system at the hepatic and central level by Di-isononyl phthalate and Bisphenol A (Italy/Greece/Spain) (click “open access” then click “digitalcsices” for download-2018) https://www.semanticscholar.org/paper/Endocrine-disruptors-in-the-diet-of-male-Sparus-of-Forner-Piquer-Mylonas/27362c0d8849549f7d092085d558d0d17201a7cd
Disruption of the gonadal endocannabinoid system in zebrafish exposed to diisononyl phthalate. (Italy/ Canada) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0269749118304007
Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season (Italy/Greece/Canada/Spain) (abst–2019) https://link.springer.com/article/10.1007%2Fs00204-018-2378-6
https://www.semanticscholar.org/paper/Effects-of-diisononyl-phthalate-(DiNP)-on-the-and-Forner-Piquer-Mylonas/281860ee1345726c1a8b93240fb67dbbb90ca495
PINACA GROUP
Manual for use by national drug analysis laboratories Recommended methods for the Identification and Analysis of Synthetic Cannabinoid Receptor Agonists in Seized Materials (link to download–2013) http://www.unodc.org/documents/scientific/STNAR48_Synthetic_Cannabinoids_ENG.pdf
AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol-Like Effects in Mice. (USA) (full – 2015) http://jpet.aspetjournals.org/content/354/3/328.full
Unintentional Pediatric Exposure to a Synthetic Cannabinoid (AB-PINACA) Resulting in Coma and Intubation. (USA) (full – 2015) http://www.annemergmed.com/article/S0196-0644%2815%2900426-6/fulltext
Concentrations of AB-CHMINACA and AB-PINACA and Driving Behavior in Suspected Impaired Driving Cases. (USA) (full – 2015) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bkv091
Postmortem distribution of MAB-CHMINACA in body fluids and solid tissues of a human cadaver. (Japan) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525191/
Schedules of Controlled Substances: Extension of Temporary Placement of PB-22, 5F- PB-22, AB-FUBINACA and ADB-PINACA in Schedule I of the Controlled Substances Act. final order. (full – 2015) https://www.federalregister.gov/documents/2016/02/05/2016-02308/schedules-of-controlled-substances-extension-of-temporary-
placement-of-pb-22-5f-pb-22-ab-fubinaca A Common Source Outbreak of Severe Delirium Associated with Exposure to the Novel Synthetic Cannabinoid ADB-PINACA. (USA) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25726258
The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB- FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities. (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971050/
Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons. (Canada) (link to PDF – 2016) https://www.researchgate.net/publication/303713782_Pharmacological_characterization_of_emerging_synthetic_cannabinoids_in_HEK293T_cells_and_hippocampal_neurons
Effect of synthetic cannabinoids on spontaneous neuronal activity: Evaluation using Ca2+ spiking and multi-electrode arrays. (Canada) (click “open access” then “ncrpublicationscanadaca” for download – 2016) https://www.semanticscholar.org/paper/Effect-of-synthetic-cannabinoids-on-spontaneous-and-Tauskela-Comas/2932e8404f4116dc42820c86d36646a37b1ccdc0 Identification and quantification of synthetic cannabinoids in “spice-like” herbal mixtures: update of the German situation for the spring of 2015. (abst – 2016) http://link.springer.com/article/10.1007/s11419-015-0292-7
https://www.semanticscholar.org/paper/Identification-and-quantification-of-synthetic-in-a-Langer-Lindigkeit/8b010e2a3b08be81ff2159bf139e9e29f72889b1 Occupational transdermal poisoning with synthetic cannabinoid cumyl-PINACA. (Slovenia) (abst – 2016) https://www.semanticscholar.org/paper/Occupational-transdermal-poisoning-with-synthetic-Dobaja-Grenc/77f4256c4b78c268e26a5fe88c38c6aec78c4f8b
Motor vehicle collisions caused by the ‘super-strength’ synthetic cannabinoids, MAM- 2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014. (Japan) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486620/
Synthetic Cannabinoid and Mitragynine Exposure of Law Enforcement Agents During the Raid of an Illegal Laboratory — Nevada, 2014 . (USA) (full – 2017) https://www.cdc.gov/mmwr/volumes/66/wr/mm6647a3.htm
Identification of 5-Fluoro ADB in Human Whole Blood in Four Death Cases. (Japan) (full – 2017) https://academic.oup.com/jat/article/42/2/e21/4656135
Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. (USA/ Australia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363769/
Acute and residual effects in adolescent rats resulting from exposure to the novel synthetic cannabinoids AB-PINACA and AB-FUBINACA. (Australia) (link to PDF–2017) https://www.researchgate.net/publication/312491240_Acute_and_residual_effects_in_adolescent_rats_resulting_from_exposure_to_the_novel_synthetic_cannabinoids_AB-PINACA_and_AB-FUBINACA
Schedules of Controlled Substances: Temporary Placement of Six Synthetic Cannabinoids (5F-ADB, 5F-AMB, 5F-APINACA, ADB-FUBINACA, MDMB- CHMICA and MDMB-FUBINACA) into Schedule I. Temporary Scheduling Order. (click “LinkOut” for download – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28425681
Intoxication from the novel synthetic cannabinoids AB-PINACA and ADB-PINACA: A case series and review of the literature. (USA) (click “ucsfedu” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Intoxication+from+the+novel+synthetic+cannabinoids+AB- PINACA+and+ADB-PINACA%3A+A+case+series+and+review+of+the+literature%22&btnG
The “Spice” Trade A Profit Estimation of EU Online Vendors of Herbal Smoking Mixtures. (abst – 2017) http://journals.sagepub.com/doi/abs/10.1177/1057567717745345
Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC. (USA) (full – 2018) https://www.frontiersin.org/articles/10.3389/fphar.2018.01084/full
A Validated Method for the Detection of Synthetic Cannabinoids in Oral Fluid. (Australia) (full – 2018) https://academic.oup.com/jat/article/43/1/10/5060433
5F-Cumyl-PINACA in ‘e-liquids’ for electronic cigarettes: comprehensive characterization of a new type of synthetic cannabinoid in a trendy product including investigations on the in vitro and in vivo phase I metabolism of 5F-Cumyl-PINACA and its non-fluorinated analog Cumyl-PINACA. (Germany/ Switzerland) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315005/
Testing for AB-PINACA in human hair: Distribution in head hair versus pubic hair. (France) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30604522
4(PM49)
Synthetic cannabinoid quinones: Preparation, in-vitro antiproliferative effects and in-vivo prostate antitumor activity (abst–2013) http://www.sciencedirect.com/science/article/pii/S0223523413006247
43(PM226)
Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis. (Spain/ USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321205/
PnPP-19
PnPP-19, a spider toxin peptide, induces peripheral antinociception through opioid and cannabinoid receptors and inhibition of neutral endopeptidase. (Brazil) (full – 2016) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13448
PrNMI
A peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer- induced bone pain. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095738/#__ffn_sectitle
Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883926/
PSN-632408
Direct activation of the proposed anti-diabetic receptor, GPR119 in cardiomyoblasts decreases markers of muscle metabolic activity (abst–2015) https://www.semanticscholar.org/paper/Direct-activation-of-the-proposed-anti-diabetic-in-Cornall-Hryciw/9b83bc3d0a6cd6640b923a39786a06d3130db371
RCS-4
Determination of 22 synthetic cannabinoids in human hair by liquid chromatography- tandem mass spectrometry. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S1570023212004023
Identification and Structural Elucidation of Four Cannabimimetic Compounds (RCS-4, AM-2201, JWH-203 and JWH-210) in Seized Products. (full – 2013) https://academic.oup.com/jat/article/37/2/56/857976
Manual for use by national drug analysis laboratories Recommended methods for the Identification and Analysis of Synthetic Cannabinoid Receptor Agonists in Seized Materials. (link to download – 2013) http://www.unodc.org/documents/scientific/STNAR48_Synthetic_Cannabinoids_ENG.pdf
Genotoxic properties of XLR-11, a widely consumed synthetic cannabinoid, and of the benzoyl indole RCS-4. (Austria/ Germany) (full – 2016) http://link.springer.com/article/10.1007/s00204-016-1664-4/fulltext.html
Distribution of Synthetic cannabinoids JWH-210, RCS-4 and ∆ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs. (Germany) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771047/
Metabolic patterns of JWH-210, RCS-4, and THC in pig urine elucidated using LC-HR- MS/MS: Do they reflect patterns in humans? (Germany) (abst – 2016) https://www.semanticscholar.org/paper/Metabolic-patterns-of-JWH-210%2C-RCS-4%2C-and-THC-in-Do-Schaefer-elfer/0c7483a327bedf24f2baed067a751f53f1c10490
A Validated Method for the Detection of Synthetic Cannabinoids in Oral Fluid. (Australia) (full – 2018) https://academic.oup.com/jat/article/43/1/10/5060433
Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques? (Germany) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218302971
R-FLURBIPROFEN
R-Flurbiprofen Reduces Neuropathic Pain in Rodents by Restoring Endogenous Cannabinoids (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869361/
R-flurbiprofen, a novel nonsteroidal anti-inflammatory drug, decreases cell proliferation and induces apoptosis in pituitary adenoma cells in vitro (link to PDF–2012) https://www.researchgate.net/publication/51662230_R-Flurbiprofen_a_novel_nonsteroidal_anti-inflammatory_drug_decreases_cell_proliferation_and_induces_apoptosis_in_pituitary_adenoma_cells_in_vitro
R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer’s disease (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863610/
R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice (full–2014) http://embomolmed.embopress.org/content/6/11/1398.long
RHC-80267
Control of Inhibition by the Direct Action of Cannabinoids on GABAA Receptors (full–2014) http://cercor.oxfordjournals.org/content/early/2014/03/18/cercor.bhu045.long
Disease-Modifying Effects of RHC80267 and JZL184 in a Pilocarpine Mouse Model of Temporal Lobe Epilepsy (1st page–2014) https://www.deepdyve.com/lp/wiley/disease-modifying-effects-of-rhc-80267-and-jzl-184-in-a-pilocarpine-gEzp8TZgv4
A Basal Tone of 2-Arachidonoylglycerol Contributes to Early Oligodendrocyte Progenitor Proliferation by Activating Phosphatidylinositol 3-Kinase (PI3K)/AKT and the Mammalian Target of Rapamycin (MTOR) Pathways. (Spain) (abst – 2015) https://www.semanticscholar.org/paper/A-Basal-Tone-of-2-Arachidonoylglycerol-Contributes-Gomez-S%C3%A1nchez-Rodriguez/a1a2c928ed595ab1c2d65198c734cf50ca526064
Activation of CB1 receptors by 2-arachidonoylglycerol attenuates vasoconstriction induced by U46619 and angiotensin II in human and rat pulmonary arteries. (Poland) (full – 2017) https://www.physiology.org/doi/full/10.1152/ajpregu.00324.2016
Fatty acid amide hydrolase (FAAH) inhibitor PF-3845 reduces viability, migration and invasiveness of human colon adenocarcinoma Colo-205 cell line: an in vitro study. (Poland) (full – 2017) https://ojs.ptbioch.edu.pl/index.php/abp/article/view/1520/1189
Modulation of the endocannabinoid system by the fatty acid amide hydrolase, monoacylglycerol and diacylglycerol lipase inhibitors as an attractive target for secretory diarrhoea therapy. (Poland) (link to download – 2017) https://pdfs.semanticscholar.org/8cbc/d37ed15c77e65367d2cbf4be938317ef138d.pdf
RID-B
The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487498/
RIMONABANT/ACOMPLIA/SR141716/SR1
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2. (full – 2010) http://pharmrev.aspetjournals.org/content/62/4/588.full
Therapeutical use of the cannabinoids in psychiatry (full–2010) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462010000500009&lng=en&nrm=iso&tlng=en
GPR55 ligands promote receptor coupling to multiple signalling pathways. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931561/?tool=pubmed
Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes? (full – 2010) http://www.jci.org/articles/view/44099?search%5Babstract_text%5D=&search%5Barticle_text%5D=cannabinoid&search%5Bauthors_text%5D=&search%5Bfpage%5D=&search%5Btitle_text%5D=&search%5Bvolume
Perspectives of CB1 Antagonist in Treatment of Obesity: Experience of RIO-Asia. (full – 2010) http://www.hindawi.com/journals/jobes/2011/957268/
Endocannabinoid control of gastric sensorimotor function in man. (full – 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2010.04259.x/full
Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant. (full – 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2009.06549.x/full
Energetic Metabolism and Human Sperm Motility: Impact of CB1 Receptor Activation. (full – 2010) http://endo.endojournals.org/content/151/12/5882.full
The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure. (full – 2010) http://onlinelibrary.wiley.com/doi/10.1038/oby.2008.509/full
The Endocannabinoid System Tonically Regulates Inhibitory Transmission and Depresses the Effect of Ethanol in Central Amygdala. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904853/
Rimonabant-induced Delta9-tetrahydrocannabinol withdrawal in rhesus monkeys: discriminative stimulus effects and other withdrawal signs. (full – 2010) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912042/
Anxiety-like effects of SR141716-precipitated delta9-tetrahydrocannabinol withdrawal in mice in the elevated plus-maze. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923489/
Reduced neural response to reward following 7 days treatment with the cannabinoid CB1 antagonist rimonabant in healthy volunteers. (full – 2010) https://academic.oup.com/ijnp/article/13/8/1103/809017
Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004984/
Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington’s disease. (full – 2010) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931573/
Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties. (full – 2010) http://onlinelibrary.wiley.com/doi/10.1002/eji.201040667/full
Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001217/?tool=pubmed
Understanding Functional Residues of the Cannabinoid CB1 for Drug Discovery. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980537/?tool=pubmed
Abnormal-Cannabidiol-Induced Increase in Aqueous Humor Outflow. (abst – 2010) http://iovs.arvojournals.org/article.aspx?articleid=2368788&resultClick=1
Intracellular Cannabinoid Type 1 (CB1) Receptors Are Activated by Anandamide. (full – 2011) http://www.jbc.org/content/286/33/29166.full
Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158793/
CB(1) -independent mechanisms of Δ(9) -THCV, AM251 and SR141716 (rimonabant). (full – 2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.2011.01284.x/full
Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164582/
The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant’s antiobesity effects in mice. (full – 2011) http://onlinelibrary.wiley.com/doi/10.1038/oby.2011.250/full
Chronic Δ⁹-tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and cross-tolerance among cannabinoids. (full – 2011) http://europepmc.org/articles/PMC3051379
Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038245/
Central mediation and differential blockade by cannabinergics of the discriminative stimulus effects of the cannabinoid CB1 receptor antagonist rimonabant in rats. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727221/
Effects of the cannabinoid-1 receptor antagonist rimonabant on psychiatric symptoms in overweight people with schizophrenia: a randomized, double-blind, pilot study. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717343/
CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606913/
Effects of Chronic Oral Rimonabant Administration on Energy Budgets of Diet-Induced Obese C57BL/6 Mice. (full – 2011) https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2011.357
Effect of rimonabant on oesophageal motor function in man. (full – 2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2011.04576.x/full
Antagonist-elicited cannabis withdrawal in humans. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717344/
Acetaminophen inhibits status epilepticus in cultured hippocampal neurons. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052417/
Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation. (full – 2011) http://www.jimmunol.org/content/187/12/6508.full?sid=c3422dd2-7ad0-42e4-a862-845dc670f7cf
The Endogenous Cannabinoid 2-Arachidonoylglycerol Is Intravenously Self- Administered by Squirrel Monkeys. (full – 2011) http://www.jneurosci.org/content/31/19/7043.long#abstract-1
Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224879/
Functional selectivity in CB2 cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB2 ligands. (full – 2011) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263955/
The GPCR – associated sorting protein 1 regulates ligand-induced downregulation of GPR55. (full – 2011) http
://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366063/ A role for the ventral hippocampal endocannabinoid system in fear-conditioned analgesia and fear responding in the presence of nociceptive tone in rats. (full – 2011) https://www.academia.edu/640786/Role_of_the_ventral_hippocampal_endocannabinoid_system_in_fear-
conditioned_analgesia_and_fear_responding_in_the_presence_of_nociceptive_tone Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat. (link to PDF – 2011) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Sex+Differences+in+Cannabinoid+1+vs.+Cannabinoid+2+Receptor-Selective+Antagonism+of+Antinociception+Produced+by+%CE%949-Tetrahydrocannabinol+and+CP55%2C940+in+the+Rat&btnG
Investigations of the endocannabinoid system in adipose tissue: effects of obesity/ weight loss and treatment options. (link to PDF – 2011) https://www.researchgate.net/publication/49840839_Investigations_of_the_human_endocannabinoid_system_in_two_subcutaneous_adipose_tissue_depots_in_lean_subjects_and_in_obese_subjects_before_and_after_weight_loss
Cannabinoid mediated diuresis in mice. (download – 2011) Cannabinoid mediated diuresis in mice – Northeastern University Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism. (link to download – 2011) http://www.nature.com/cddis/journal/v2/n4/pdf/cddis201136a.pdf
Endocannabinoid system protects against cryptogenic seizures. (link to download – 2011) http://www.if-pan.krakow.pl/pjp/pdf/2011/1_165.pdf
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. (click “uclouvaibn” for download – 2011) https://scholar.google.com/scholar?q=Increasing+endogenous+2-
arachidonoylglycerol+levels+counteracts+colitis+and+related+systemic+inflammation&hl=en&as_sdt=0&as_vis=1&oi=scholart Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors. (click “academia” for download – 2011) https://scholar.google.com/scholar?q=Nonopioid+placebo+analgesia+is+mediated+by+CB1+cannabinoid+receptors.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Bioactivation Pathways of the Cannabinoid Receptor 1 Antagonist Rimonabant (click “aspetjournals” for download – 2011) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Bioactivation+Pathways+of+the+Cannabinoid+Receptor+1+Antagonist+Rimonabant&btnG
Neuropsychiatric adverse effects of centrally acting antiobesity drugs (1st page–2011) https://www.deepdyve.com/lp/wiley/neuropsychiatric-adverse-effects-of-centrally-acting-antiobesity-drugs-Sy0a9pYcBp
The CB-1 Receptor Antagonist Rimonabant Modulates the Interaction Between Adipocytes and Pancreatic Beta-Cells in Vitro (link to 1st page – 2011) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1261963
Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts. (abst in English – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21575494
(abst in Chinese – 2011) http://zhzlzz.yiigle.com/CN112152201104/37688.htm?locale=zh_CN
The role of the cannabinoid system in the pathogenesis and treatment of alcohol dependence. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21934185
The identification of rimonabant polymorphs, sibutramine and analogues of both in counterfeit Acomplia bought on the internet. (abst – 2011) https://www.sciencedirect.com/science/article/abs/pii/S0731708510004334?via%3Dihub
Pro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy. (abst – 2011) https://www.semanticscholar.org/paper/Pro-epileptic-effects-of-the-cannabinoid-receptor-a-Vinogradova-Shatskova/6d0fa9aae15302d47b8c8609b4065adee34cf8cf
Disruptive effects of the prototypical cannabinoid Δ⁹-tetrahydrocannabinol and the fatty acid amide inhibitor URB-597 on go/no-go auditory discrimination performance and olfactory reversal learning in rats. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21512341
Effects of the cannabinoid antagonist SR 141716 on sexual and motor behavior in receptive female rats. (abst – 2011) https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1440-1681.2011.05587.x
CB1 cannabinoid receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22211674
Naloxone and rimonabant reduce the reinforcing properties of exercise in rats. (abst – 2011) https://www.semanticscholar.org/paper/Naloxone-and-rimonabant-reduce-the-reinforcing-of-Rasmussen-Hillman/5ca51e017914f3fd896fc978df0928922292bb98 2-Arachidonoylglycerol (2-AG) Induces Corneal Epithelial Cell Migration via Cannabinoid CB1 Receptors. (abst – 2011) http://iovs.arvojournals.org/article.aspx?articleid=2352973&resultClick=1
Effects of cannabinoid CB(1) receptor agonism and antagonism on SKF81297-induced dyskinesia and haloperidol-induced dystonia in Cebus apella monkeys. (abst – 2011) http://www.sciencedirect.com/science/article/pii/S0028390810002844
The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro. (abst – 2011) http://www.sciencedirect.com/science/article/pii/S0197018611002269
Probing the Interaction of SR141716A with the CB1 Receptor. (full – 2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493917/
The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABAA receptors. (full – 2012) http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01405.x/full
Relationships between glucose, energy intake and dietary composition in obese adults with type 2 diabetes receiving the cannabinoid 1 (CB1) receptor antagonist, rimonabant . (full – 2012) http://www.nutritionj.com/content/11/1/50
Does rimonabant independently affect free fatty acid and glucose metabolism? (full – 2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319222/
Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis. (full – 2012) http://ajpendo.physiology.org/content/303/4/E475.long
GPR18 in microglia: implications for the CNS and endocannabinoid system signaling. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525861/
Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors. (full – 2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438986/
The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55. (full – 2012) http://www.jbc.org/content/287/53/44234.full?sid=a47387d6-533c-461e-834f-1491b62b890a
Rimonabant eliminates responsiveness to workload changes in a time-constrained food- reinforced progressive ratio procedure in rats. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387812/
Endocannabinoid signaling in female reproduction. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382454/
Extinction learning of rewards in the rat: is there a role for CB1 receptors? (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161161/
Pharmacological modulation of the endocannabinoid signalling alters binge-type eating behaviour in female rats. (full – 2012) http://onlinelibrary.wiley.com/doi/10.1111/bph.12014/full
Structural analogs of pyrazole and sulfonamide cannabinoids: Effects on acute food intake in mice. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586205/
Cannabinoid facilitation of behavioral and biochemical hedonic taste responses. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705914/
Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE). (full – 2012) http://fampra.oxfordjournals.org/content/29/5/521.full
Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility. (full – 2012) http://www.jneurosci.org/content/32/30/10331.long
Δ9-Tetrahydrocannabinol attenuates MDMA-induced hyperthermia in rhesus monkeys. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258357/
Endocannabinoid system: A newer molecular target for the treatment of alcohol-related behaviors. (full – 2012) http://www.wjgnet.com/2220-3192/full/v1/i3/44.htm
Photoperiodic Changes in Endocannabinoid Levels and Energetic Responses to Altered Signalling at CB1 Receptors in Siberian Hamsters. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060156/
Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature. (full – 2012) http://www.harmreductionjournal.com/content/9/1/7
Expression of fatty acid amide hydrolase (FAAH) in human, mouse, and rat urinary bladder and effects of FAAH inhibition on bladder function in awake rats. (full – 2012) http://www.europeanurology.com/article/S0302-2838(11)01002-5/fulltext
Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists. (full – 2012) http://onlinelibrary.wiley.com/doi/10.1002/jbmr.1732/full
Excitability of prefrontal cortical pyramidal neurons is modulated by activation of 98 intracellular type-2 cannabinoid receptors. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295302/
Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249141/
Effect of delta-9-tetrahydrocannabinol on behavioral despair and on presynaptic and postsynaptic serotonergic transmission. (full – 2012) https://www.academia.edu/22887765/Effect_of_delta-9-tetrahydrocannabinol_on_behavioral_despair_and_on_pre-_and_postsynaptic_serotonergic_transmission
The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: Evidence from postmortem human brain. (full – 2012) https://www.academia.edu/17507457/The_inverse_agonist_effect_of_rimonabant_on_G_protein_activation_is_not_mediated_by_the_cannabinoid_CB1_receptor_Evidence_from_postmortem_human_brain
To Be or Not To Be—Obese. (full – 2012) https://academic.oup.com/endo/article/152/10/3592/2457128
Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-inudced obese mice. (full – 2012) https://www.nature.com/articles/ijo201235
Involvement of a non-CB1/CB2 cannabinoid receptor in the aqueous humor outflow- enhancing effects of abnormal-cannabidiol. (full – 2012) https://www.academia.edu/4595529/Involvement_of_a_non-CB1_CB2_cannabinoid_receptor_in_the_aqueous_humor_outflow-enhancing_effects_of_abnormal-cannabidiol
Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice (link to PDF–2012) https://www.researchgate.net/publication/229015737_Hypothalamic_CB1_Cannabinoid_Receptors_Regulate_Energy_Balance_in_Mice
The role of CB2 receptor ligands in human eosinophil function (link to download–2012) http://www.biomedcentral.com/content/pdf/2050-6511-13-S1-A13.pdf
Induction of Glucose Intolerance by Acute Administration of Rimonabant. (click “academia” for download – 2012) https://scholar.google.com/scholar?q=Induction+of+glucose+intolerance+by+acute+administration+of+rimonabant.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Fatty acid flux and oxidation are increased by rimonabant in obese women. (click “coreacuk” for download – 2012) https://scholar.google.com/scholar?cluster=6204002522981162748&hl=en&as_sdt=0,5
Cannabinoid CB(1) receptor in the modulation of stress coping behaviour in mice: the role of serotonin and different forebrain neuronal subpopulations. (click “unibonn” for download – 2012) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Cannabinoid+CB1+receptor+in+the+modulation+of+stress+coping+behavior+in+mice%3A+The+role+of+serotonin+and+different+forebrain+neuronal+subpopulations&btnG
Rimonabant reduces the essential value of food in the genetically obese Zucker rat: An exponential demand analysis. (abst – 2012) https://www.sciencedirect.com/science/article/abs/pii/S0031938411004860?via%3Dihub
Cannabinoids ameliorate disease progression in a model of multiple sclerosis in mice, acting preferentially through CB(1) receptor-mediated anti-inflammatory effects. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S0028390812000500
https://www.semanticscholar.org/paper/Cannabinoids-ameliorate-disease-progression-in-a-of-Lago-Moreno-Martet/b6fc028f0ac5d244a9301fcad6fb83fca6df3ff8 Effects of cannabinoid receptor agonist WIN 55,212-2 on blood-brain barrier disruption in focal cerebral ischemia in rats. (abst – 2012) https://www.karger.com/Article/Abstract/338755
Effects of amphetamine on dopamine release in the rat nucleus accumbens shell region depend on cannabinoid CB1 receptor activation. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S0197018612000952
Ibipinabant attenuates β-cell loss in male Zucker diabetic fatty rats independently of its effects on body weight. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22268426
Antipsychotic Profile of Cannabidiol and Rimonabant in an Animal Model of Emotional Context Processing in Schizophrenia. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22716146
Bioactivation of the Cannabinoid Receptor Antagonist Rimonabant to a Cytotoxic Iminium Ion Metabolite. (abst – 2012) http://pubs.acs.org/doi/abs/10.1021/tx300418w
Reports of the death of CB1 antagonists have been greatly exaggerated: recent preclinical findings predict improved safety in the treatment of obesity. (abst – 2012) https://www.semanticscholar.org/paper/Reports-of-the-death-of-CB1-antagonists-have-been-Mclaughlin/1599f8eac0ccb880299e6095c9340aac9a145313
Effect of Oleoylethanolamide on Aqueous Humor Outflow. (abst – 2012) http://iovs.arvojournals.org/article.aspx?articleid=2352002&resultClick=1
Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration. (abst – 2012) https://www.semanticscholar.org/paper/Effects-of-the-anandamide-uptake-blocker-AM404-on-Reyes-Cabello-Al%C3%A9n/9a85cb2b5657534daf1f3c7ad53d2d49677ce202 The effects of fasting duration on gastric emptying in man, an exploration of the role of the endocannabinoid system and inter-individual responsiveness. (abst – 2012) https://www.semanticscholar.org/paper/The-effects-of-fasting-duration-on-gastric-emptying-Jones-Dockray/f73a669bceca7516426ba3a61704f9b861b23099
WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination. (abst – 2012) https://www.sciencedirect.com/science/article/pii/S0006899312018008
How Weed Can Protect Us From Cancer and Alzheimer’s (book excerpt-forum repost–2012) http://www.alternet.org/story/156269/how_weed_can_protect_us_from_cancer_and_alzheimer%27s
Ghrelin-Induced Orexigenic Effect in Rats Depends on the Metabolic Status and Is Counteracted by Peripheral CB1 Receptor Antagonism. (full – 2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060918
Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854987/
Diuretic effects of cannabinoids. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533417/
Cannabinoid signaling and liver therapeutics. (full – 2013) http://www.journal-of-hepatology.eu/article/S0168-8278%2813%2900212-2/fulltext
Bladder function in a cannabinoid receptor type 1 knock-out mouse. (full – 2013) http://onlinelibrary.wiley.com/doi/10.1111/bju.12350/full
Using the endocannabinoid system as a neuroprotective strategy in perinatal hypoxic- ischemic brain injury. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146074/
Rimonabant effects on anxiety induced by simulated public speaking in healthy humans: a preliminary report. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539121/
Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CB1 receptors: implications for schizophrenia. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717536/
The CB1 receptor mediates the peripheral effects of ghrelin on AMPK activity but not on growth hormone release. (full – 2013) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834776/
Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB1 receptor blockade. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607008/
Reduced Food Intake is the Major Contributor to the Protective Effect of Rimonabant on Islet in Established Obesity-Associated Type 2 Diabetes. (full – 2013) http://www.eymj.org/DOIx.php?id=10.3349/ymj.2013.54.5.1127
Endocannabinoids as markers of sperm quality: hot spots. (full – 2013) http://www.frontiersin.org/Journal/10.3389/fendo.2013.00169/full
Fasting induces CART down-regulation in the zebrafish nervous system in a cannabinoid receptor 1-dependent manner. (full – 2013) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416984/
The Gastric CB1 Receptor Modulates Ghrelin Production through the mTOR Pathway to Regulate Food Intake. (full – 2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0080339
Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdale. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799070/
Endocannabinoid Signaling in Hypothalamic-Pituitary-Adrenocortical Axis Recovery Following Stress: Effects of Indirect Agonists and Comparison of Male and Female Mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929302/
Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949659/
Tetrahydrocannabinolic acid reduces nausea-induced conditioned gaping in rats and vomiting in Suncus murinus. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792001/
Biphasic effects of Δ9-tetrahydrocannabinol on brain stimulation reward and motor activity. (full – 2013) http://ijnp.oxfordjournals.org/content/16/10/2273
The inverse agonist of CB1 receptor SR141716 blocks compulsive eating of palatable food. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720761/
Endocannabinoids in the Brainstem Modulate Dural Trigeminovascular Nociceptive Traffic via CB1 and “Triptan” Receptors: Implications in Migraine. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771033/
Repeated Low Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains CB1 Receptor Mediated Antinociceptive and Gastroprotective Effects. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657109/
Cannabinoid (CB)1 receptors are critical for the innate immune response to TLR4 stimulation. (full – 2013) http://www.physiology.org/doi/full/10.1152/ajpregu.00104.2013
Glutamate spillover drives endocannabinoid production and inhibits GABAergic transmission in the Substantia Nigra pars compacta. (full – 2013) https://www.academia.edu/12855406/Glutamate_spillover_drives_endocannabinoid_production_and_inhibits_GABAergic_transmission_in_the_Substantia_Nigra_pars_compacta
The combination of oral L-DOPA/rimonabant for effective dyskinesia treatment and cytological preservation in a rat model of Parkinson’s disease and L-DOPA-induced dyskinesia. (full – 2013) https://www.academia.edu/23226954/The_combination_of_oral_L-DOPA_rimonabant_for_effective_dyskinesia_treatment_and_cytological_preservation_in_a_rat_model_of_Parkinson_s_disease_and _L-DOPA-induced_dyskinesia
Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors. (full – 2013) https://kundoc.com/pdf-motor-effects-of-the-non-psychotropic-phytocannabinoid-cannabidiol-that-are-medi.html
Blockade of cannabinoid receptors reduces inflammation, leukocyte accumulation and neovascularization in a model of sponge-induced inflammatory angiogenesis. (link to PDF – 2013) https://www.researchgate.net/publication/236977025_Blockade_of_cannabinoid_receptors_reduces_inflammation_leukocyte_accumulation_and_neovascularization_in_a_model_of_sponge-induced_inflammatory_angiogenesis
Novel Insights Into CB1 Cannabinoid Receptor Signaling: A Key Interaction Identified Between EC3-Loop and TMH2. (link to PDF – 2013) https://www.researchgate.net/publication/235682536_Novel_Insights_Into_CB1_Cannabinoid_Receptor_Signaling_A_Key_Interaction_Identified_Between_EC3-Loop_and_TMH2
Stimulatory and Inhibitory Roles of Brain 2-Arachidonoylglycerol in Bombesin-Induced Central Activation of Adrenomedullary Outflow in Rats. (link to download – 2013) https://www.jstage.jst.go.jp/article/jphs/121/2/121_12208FP/_pdf
The Role of the Endocannabinoid System in Eating Disorders: Neurochemical and Behavioural Preclinical Evidence. (link to download – 2013) The role of the endocannabinoid system in eating disorders … Islet cannabinoid receptors: cellular distribution and biological function. (click “conicet” for download – 2013) https://scholar.google.com/scholar?q=Islet+cannabinoid+receptors:+cellular+distribution+and+biological+function.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Additive effect of rimonabant and citalopram on extracellular serotonin levels monitored with in vivo microdialysis in rat brain (click “uchile” for download–2013) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Additive+effect+of+rimonabant+and+citalopram+on+extracellular+serotonin+levels+monitored+with+in+vivo+microdialysis+in+rat+brain.&btnG Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats. (click “researchgate” for download – 2013) https://scholar.google.com/scholar?q=Effects+of+CB1+receptor+blockade+on+monosodium+glutamate+induced+hypometabolic+and+hypothalamic+obesity+in+rats&hl=en&as_sdt=0&as_vis=1&oi=scholart Sex differences in anti-allodynic, anti-hyperalgesic and anti-edema effects of Δ9- tetrahydrocannabinol in the rat. (click “theroc” for download – 2013) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Sex+differences+in+anti-allodynic%2C+anti-hyperalgesic+and+anti-edema+effects+of+%CE%94%289%29-tetrahydrocannabinol+in+the+rat.&btnG
Endocannabinoids underlie reconsolidation of hedonic memories in Wistar rats. (click “researchgate” for download – 2013) https://scholar.google.com/scholar?q=Endocannabinoids+underlie+reconsolidation+of+hedonic+memories+in+Wistar+rats.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Erratum to: Endocannabinoids underlie reconsolidation of hedonic memories in Wistar rats. (correction – 2013) http://link.springer.com/article/10.1007%2Fs00213-013-3380-6
Cannabis and Δ(9)-tetrahydrocannabinol (THC) for weight loss? (abst – 2013) https://www.semanticscholar.org/paper/Cannabis-and-%CE%949-tetrahydrocannabinol-(THC)-for-loss-Foll-Trigo/825e51737f6240d51cbddc11b7b3c498bc659f37
Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S0968089613000941
Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S0091305712002985
Synergetic Insulin Sensitizing Effect of Rimonabant and BGP-15 in Zucker-Obese Rats. (abst – 2013) https://link.springer.com/article/10.1007%2Fs12253-013-9620-6
Infusion of cannabidiol into infralimbic cortex facilitates fear extinction via CB1 receptors. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S0166432813002532
Effects of the cannabinoid 2 receptor-selective agonist GW405833 in assays of acute pain-stimulated and paindepressed behavior in rats. (abst – 2013) https://www.fasebj.org/doi/10.1096/fasebj.27.1_supplement.886.9
Dysregulation of Cannabinoid CB1 Receptor and Associated Signaling Networks in Brains of Cocaine Addicts and Cocaine-Treated Rodents. (abst – 2013) https://www.sciencedirect.com/science/article/abs/pii/S0306452213004636?via%3Dihub
Low dose naloxone attenuates the pruritic but not anorectic response to rimonabant in male rats. (abst – 2013) https://www.semanticscholar.org/paper/Low-dose-naloxone-attenuates-the-pruritic-but-not-Wright-Rodgers/2810cd55605c6c4bf54ffda29636544bfec235f8
CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23860329
2-arachidonoylglycerol interferes with lithium-induced vomiting in the house musk shrew, Suncus murinus. (abst – 2013) https://www.sciencedirect.com/science/article/abs/pii/S0031938413002631?via%3Dihub
Expression of the cannabinoid receptor type 1 in the pituitary of rabbits and its role in the control of LH secretion. (abst – 2013) https://www.sciencedirect.com/science/article/pii/S0739724013000945?via%3Dihub
Low brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: A PET study (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24293119
The role of Cannabinoid receptors on light-induced photoreceptor degeneration (abst–2013) http://iovs.arvojournals.org/article.aspx?articleid=2149928&resultClick=1
Mechanisms of vasorelaxation induced by oleoylethanolamide in the rat small mesenteric artery. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23340219
Getting high on the endocannabinoid system. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295/
Involvement of the cannabinoid CB1 receptor in modulation of dopamine output in the prefrontal cortex associated with food restriction in rats. (full – 2014) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092224
Vascular targets for cannabinoids: animal and human studies. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954478/
2012 Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective. (USA) (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064474/
Oleoylethanolamide: a novel potential pharmacological alternative to cannabinoid antagonists for the control of appetite. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996326/
Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707667/
Combining rimonabant and fentanyl in a single entity: preparation and pharmacological results. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934591/
Endocannabinoid 2-Arachidonoylglycerol Self-Administration by Sprague-Dawley Rats and Stimulation of in vivo Dopamine Transmission in the Nucleus Accumbens Shell. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201088/
Behavioral effects of the cannabinoid CB1 receptor allosteric modulator ORG27569 in rats. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186448/
Antagonism of cannabinoid receptor 2 pathway suppresses IL-6-induced immunoglobulin IgM secretion. (full – 2014) http://www.biomedcentral.com/2050-6511/15/30
Evaluation of WIN 55,212-2 self-administration in rats as a potential cannabinoid abuse liability model. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930061/
Evaluation of sex differences in cannabinoid dependence. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971653/
Rimonabant’s reductive effects on high densities of food reinforcement, but not palatability, in lean and obese Zucker rats. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036064/
Neural Effects of Cannabinoid CB1 Neutral Antagonist Tetrahydrocannabivarin (THCv) on Food Reward and Aversion in Healthy Volunteers. (full – 2014) http://ijnp.oxfordjournals.org/content/18/6/pyu094.long
The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996125/
Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1 receptors. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243853/
Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa. (full – 2014) http://onlinelibrary.wiley.com/doi/10.1111/j.2047-2927.2014.00210.x/full
Baseline Anandamide Levels and Body Weight Impact the Weight Loss Effect of CB1 Receptor Antagonism in Male Rats. (full – 2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399312/
The CB1 Receptor as an Important Mediator of Hedonic Reward Processing. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138748/
Ultramicronized palmitoylethanolamide normalizes intestinal motility in a murine model of post-inflammatory accelerated transit: involvement of CB1 receptors and TRPV1. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243976/
Acute Activation of Cannabinoid Receptors by Anandamide Reduces Gastro-Intestinal Motility and Improves Postprandial Glycemia in Mice. (full – 2014) http://diabetes.diabetesjournals.org/content/64/3/808.long
Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis. (full – 2014) http://hyper.ahajournals.org/content/64/3/619.long
Haloperidol and rimonabant increase delay discounting in rats fed high-fat and standard- chow diets. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772744/
Cannabidiol fails to reverse hypothermia or locomotor suppression induced by Δ9- tetrahydrocannabinol in Sprague-Dawley rats. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376456/
Dual inhibition of monoacylglycerol lipase and cyclooxygenases synergistically reduces neuropathic pain in mice. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376450/
Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors. (full – 2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059893/
In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid Δ9-THC in mice: inhalation versus intraperitoneal injection. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340656/
Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765324/
The endocannabinoid system and appetite: relevance for food reward. (full – 2014) https://www.cambridge.org/core/journals/nutrition-research-reviews/article/endocannabinoid-system-and-appetite-relevance-for-food-reward/30C65E719848770761B6BEA7D0C1E9CB/core-reader Modulation of pilocarpine-induced seizures by cannabinoid receptor 1. (full – 2014) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0095922
Control of Inhibition by the Direct Action of Cannabinoids on GABAA Receptors. (full – 2014) http://cercor.oxfordjournals.org/content/early/2014/03/18/cercor.bhu045.long
Anandamide attenuates haloperidol-induced vacuous chewing movements in rats. (full – 2014) https://docksci.com/anandamide-attenuates-haloperidol-induced-vacuous-chewing-movements-in-rats_5ae5d04ad64ab2d12eaffffe.html
Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting. (full – 2014) https://kundoc.com/pdf-distinct-modulation-of-the-endocannabinoid-system-upon-kainic-acid-induced-in-vi.html
Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice. (full – 2014) https://www.academia.edu/20107281/Guineensine_is_a_novel_inhibitor_of_endocannabinoid_uptake_showing_cannabimimetic_behavioral_effects_in_BALB_c_mice Allosteric Modulation of a Cannabinoid G Protein-coupled Receptor BINDING SITE ELUCIDATION AND RELATIONSHIP TO G PROTEIN SIGNALING. (full – 2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937654/
Prolonged monoacylglycerol lipase blockade causes equivalent CB1-receptor mediated adaptations in FAAH wild type and knockout mice. (link to PDF – 2014) http://jpet.aspetjournals.org/content/early/2014/05/21/jpet.114.212753.long
Early increase of cannabinoid receptor density after experimental traumatic brain injury in the newborn piglet. (link to PDF – 2014) https://www.researchgate.net/publication/263708321_Early_increase_of_cannabinoid_receptor_density_after_experimental_traumatic_brain_injury_in_the_newborn_piglet
Early phytocannabinoid chemistry to endocannabinoids and beyond (Israel/Scotland/USA) (link to PDF– 2014) https://www.researchgate.net/publication/266945311_Early_phytocannabinoid_chemistry_to_endocannabinoids_and_beyond
Δ9-tetrahydrocannabinol prevents methamphetamine-induced neurotoxicity. (link to download – 2014) http://www.plosone.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pone.0098079&representation=PDF
Gene-Specific Disruption of Endocannabinoid Receptor 1 (cnr1a) by Ethanol Probably Leads to the Development of Fetal Alcohol Spectrum Disorder (FASD) Phenotypes in Japanese Rice Fish (Oryzias latipes) Embryogenesis. (click “usda” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Gene-
specific+disruption+of+endocannabinoid+receptor+1+%28cnr1a%29+by+ethanol+probably+leads+to+the+development+of+fetal+alcohol+spectrum+disorder+%28FASD%29+phenotypes+in+Japanese+rice+fish+%28Oryzias+latipes%29+embryogenesis.&btnG=
Cannabinoid CB1 receptor signaling dichotomously modulates inhibitory and excitatory synaptic transmission in rat inner retina. (click “nsfcgovcn” for download – 2014) https://scholar.google.com/scholar?q=Cannabinoid+CB1+receptor+signaling+dichotomously+modulates+inhibitory+and+excitatory+synaptic+transmission+in+rat+inner+retina&hl=en&as_sdt=0&as_vis=1&oi=scholart
The endocannabinoid anandamide regulates the peristaltic reflex by reducing neuro- neuronal and neuro-muscular neurotransmission in ascending myenteric reflex pathways in rats. (click “if-pankrakowpl” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=The+endocannabinoid+anandamide+regulates+the+peristaltic+reflex+by+reducing+neuro-neuronal+and+neuro-muscular+neurotransmission+in+ascending+myenteric+reflex+pathways+in+rats&btnG
Cannabinoids negatively modulate striatal glutamate and dopamine release and behavioural output of acute d-amphetamine. (click “academia” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Cannabinoids+negatively+modulate+striatal+glutamate+and+dopamine+release+and+behavioural+output+of+acute+d-amphetamine&btnG Cannabinoid receptor type 1 receptors on GABAergic vs. glutamatergic neurons differentially gate sex-dependent social interest in mice. (click “researchgate” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Cannabinoid+receptor+type+1+receptors+on+GABAergic+vs.+glutamatergic+neurons+differentially+gate+sex-dependent+social+interest+in+mice.&btnG
Involvement of the endocannabinoid system in attentional modulation of nociceptive behaviour in rats. (click “academia” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Involvement+of+the+endocannabinoid+system+in+attentional+modulation+of+nociceptive+behaviour+in+rats.&btnG
L-DOPA disrupts adenosine A2A-cannabinoid CB1-dopamine D2 receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: Biochemical and behavioral studies. (click “academia” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=l-DOPA+disrupts+adenosine+A2A%E2%80%93cannabinoid+CB1%E2%80%93dopamine+D2+receptor+heteromer+cross- talk+in+the+striatum+of+hemiparkinsonian+rats%3A+Biochemical+and+behavioral+studies&btnG
O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus. (click “unibonn” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=O-
2050+facilitates+noradrenaline+release+and+increases+the+CB1+receptor+inverse+agonistic+effect+of+rimonabant+in+the+guinea +pig+hippocampus.&btnG
The Endocannabinoid System – Back to the Scene of Cardiometabolic Risk Factors Control? (link to 1st page – 2014) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1375653
Mechanism of endocannabinoids system in glucose metabolism of rats with chronic intermittent hypoxia. (abst in English – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25146750 (abst in Chinese-2014) http://zhyxzz.yiigle.com/CN112137201420/561542.htm?locale=zh_CN
Endocannabinoid signaling and food addiction. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0149763414002061
CB1 blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans (abst–2014) https://www.semanticscholar.org/paper/CB1-blockade-induced-weight-loss-over-48-weeks-fat-Bergholm-Sevastianova/3fac25e9c9f4e413eeffaecfd33aac5ba8488928
Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state. (abst – 2014) https://www.semanticscholar.org/paper/Microinjection-of-2-arachidonoyl-glycerol-into-the-Rea-Ford/8d70a162f8f889cddf6792f5243074eef92b1c3a
Micromolar concentrations of rimonabant directly inhibits delta opioid receptor specific ligand binding and agonist-induced G-protein activity. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0197018613003239
Effects of cannabinoid and vanilloid drugs on positive and negative-like symptoms on an animal model of schizophrenia: The SHR strain. (abst – 2014) https://www.semanticscholar.org/paper/Effects-of-cannabinoid-and-vanilloid-drugs-on-and-Almeida-Peres/d2fa3532330311be785f9146bf517588dfcd1682
Inhibition of Peripheral Fatty Acid Amide Hydrolase Depresses Activities of Bladder Mechanosensitive Nerve Fibers of the Rat. (abst – 2014) https://www.sciencedirect.com/science/article/pii/S0022534714033345
CB1 receptor antagonism in the granular insular cortex or somatosensory area facilitates consolidation of object recognition memory. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0304394014005370
Ultralow doses of cannabinoid drugs protect the mouse brain from inflammation-induced cognitive damage. (abst – 2014) https://www.semanticscholar.org/paper/Ultralow-doses-of-cannabinoid-drugs-protect-the-Fishbein-Kaminietsky-Gafni/7543d1bbca2aa3d39ca4d5a241be95912881acb8
Functional consequences of synthetic cannabinoid metabolites and CYP2C9 polymorphisms. (abst – 2014) https://www.fasebj.org/doi/10.1096/fasebj.28.1_supplement.838.4
The FAAH inhibitor PF-04457845 has THC-like rewarding and reinstatement effects in squirrel monkeys and increases dopamine levels in the nucleus accumbens shell in rats. (abst – 2014) https://www.fasebj.org/doi/10.1096/fasebj.28.1_supplement.838.6
Endocannabinoid Influence on Partner Preference in Female Rats. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0091305714002068
Analysis in conditional cannabinoid 1 receptor-knockout mice reveals neuronal subpopulation-specific effects on epileptogenesis in the kindling paradigm. (abst – 2014) https://www.sciencedirect.com/science/article/pii/S0969996114002307?via%3Dihub
Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus. (abst – 2014) https://www.semanticscholar.org/paper/Effect-of-selective-inhibition-of-monoacylglycerol-Parker-Niphakis/99f5a2140263e155e92712ccae8c1a262a01a077 Mn-SOD Upregulation by Electroacupuncture Attenuates Ischemic Oxidative Damage via CB1R-Mediated STAT3 Phosphorylation. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25432886
Protective effect of palmitoylethanolamide, a naturally-occurring molecule, in a rat model of cystitis. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25463999
Cocaine-induced endocannabinoid release modulates behavioral and neurochemical sensitization in mice. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913738/
Role for Endogenous BDNF in Endocannabinoid-Mediated Long-Term Depression at Neocortical Inhibitory Synapses . (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415885/
Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients’ cells (Italy) (full–2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558164/
Homer Protein-Metabotropic Glutamate Receptor Binding Regulates Endocannabinoid Signaling and Affects Hyperexcitability in a Mouse Model of Fragile X Syndrome. (USA) (full – 2015) http://www.jneurosci.org/content/35/9/3938.long
A cannabinoid receptor agonist N-arachidonoyl dopamine inhibits adipocyte differentiation in human mesenchymal stem cells. (Republic of Korea) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428713/
Role of the endogenous cannabinoid system in nicotine addiction: novel insights. (Canada/ USA/ Saudi Arabia) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373509/
Hormonal status and age differentially affect tolerance to the disruptive effects of delta-9- tetrahydrocannabinol (Δ(9)-THC) on learning in female rats. (USA) (full – 2015) http://journal.frontiersin.org/article/10.3389/fphar.2015.00133/full
Homeostatic regulation of brain functions by endocannabinoid signaling. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468750/
Enhancing Brain Pregnenolone May Protect Cannabis Intoxication but Should Not Be Considered as an Anti-addiction Therapeutic: Hypothesizing Dopaminergic Blockade and Promoting Anti-Reward. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545660/
Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling. (USA) (full – 2015) http://www.mdpi.com/2076-3425/5/4/456/htm
Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks. (Italy) (full – 2015) http://cercor.oxfordjournals.org/content/early/2015/11/17/cercor.bhv274.long
Cannabinoid-Induced Chemotaxis in Bovine Corneal Epithelial Cells. (USA/ Taiwan) (full – 2015) http://iovs.arvojournals.org/article.aspx?articleid=2297919&resultClick=1
Proapoptotic effect of endocannabinoids in prostate cancer cells. (Chile) (full – 2015) http://www.spandidos-publications.com/or/33/4/1599
Deletion of Monoglyceride glyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-Induced Neuroinflammation. (Austria/ Germany/ Netherlands) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705409/
Influence of rimonabant treatment on peripheral blood mononuclear cells; flow cytometry analysis and gene expression profiling. (Sweden/ Belgium) (full – 2015) https://peerj.com/articles/1056/
Roles for the endocannabinoid system in ethanol-motivated behavior. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679600/
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Cannabinoid CB1 receptors and mTORC1 signalling pathway interact to modulate glucose homeostasis. (Spain/ France) (full – 2015) http://dmm.biologists.org/content/9/1/51.long
Role of the Endocannabinoid System in Diabetes and Diabetic Complications. (Italy/ USA) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1111/bph.13226/full
Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477849/
The GPR55 agonist lysophosphatidylinositol mediates vasorelaxation of the rat mesenteric resistance artery and induces calcium release in rat mesenteric artery endothelial cells. (UK/ Oman) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459022/
Simultaneous inhibition of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) shares discriminative stimulus effects with ∆9-THC in mice. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407717/
The Cannabinoid Receptor-1 is an imaging biomarker of Brown Adipose Tissue. (Finland/ Sweden) (full – 2015) http://jnm.snmjournals.org/content/56/12/1937.long
Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse. (USA/ Italy) (full – 2015) http://www.nature.com/npp/journal/v40/n9/full/npp201562a.html
Cannabinoid Receptor–Interacting Protein 1a Modulates CB1 Receptor Signaling and Regulation. (USA/ UK) (full – 2015) http://molpharm.aspetjournals.org/content/87/4/747.long
Anandamide Depresses Glycinergic and GABAergic Inhibitory Transmissions in Adult Rat Substantia Gelatinosa Neurons. (Japan) (full – 2015) http://file.scirp.org/Html/1-2500613_54452.htm
Microstructural analysis of rat ethanol and water drinking patterns using a modified operant self-administration model. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506870/
Epigenetic and Proteomic Expression Changes Promoted by Eating Addictive-like Behavior. (Italy/ Spain/ Sweden) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864655/
Endocannabinoid and nitric oxide interaction mediates food intake in neonatal chicken. (Iran) (full – 2015) http://www.tandfonline.com/doi/full/10.1080/00071668.2015.1059407
Targeting cannabinoid receptor-2 pathway by phenylacetylamide suppresses the proliferation of human myeloma cells through mitotic dysregulation and cytoskeleton disruption. (USA/ China) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504841/
The impact of gonadal hormones on cannabinoid dependence. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696547/
CB1R antagonist increases hepatic insulin clearance in fat-fed dogs likely via upregulation of liver adiponectin receptors. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609878/
Chronic ethanol exposure increases voluntary home cage intake in adult male, but not female, Long-Evans rats. (USA) (full – 2015) http://www.sciencedirect.com/science/article/pii/S0091305715300885
Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424182/
Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti- inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages. (Netherlands) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1111/bph.12747/full
Monoacylglycerol Lipase Regulates Fever Response. (USA) (full – 2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134437
Δ-9-Tetrahydrocannabinol discriminative stimulus effects of AM2201 and related aminoalkylindole analogs in rats. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779682/
Acute and Chronic Ethanol Exposure Differentially Regulate CB1 Receptor Function at Glutamatergic Synapses in the Rat Basolateral Amygdala. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912876/
A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates. (Sweden) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678037/
Lipid abundance in zebrafish embryos is regulated by complementary actions of the Endocannabinoid System and Retinoic Acid Pathway. (Australia) (full – 2015) https://academic.oup.com/endo/article/156/10/3596/2422925
A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents. (India) (full – 2015) https://docksci.com/a-comprehensive-patents-review-on-cannabinoid-1-receptor-antagonists-as-
antiobes_5a35b3c1d64ab2dbfc0f0d02.html Roles for the endocannabinoid system in ethanol-motivated behavior. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679600/
Anandamide Drives Cell Cycle Progression through CB1 Receptors in a Rat Model of Synchronized Liver Regeneration. (full – 2015) https://www.academia.edu/14486876/Anandamide_Drives_Cell_Cycle_Progression_through_CB1_Receptors_in_a_Rat_Model_of_Synchronized_Liver_Regeneration
Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor. (Australia/ New Zealand) (full – 2015) http://molpharm.aspetjournals.org/content/88/2/368.long
Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines. (Italy) (click “PDF reader” for full – 2015) https://docksci.com/anti-proliferative-and-pro-apoptotic-effects-of-flavonoid-quercetin-are-mediated_5a51d9b5d64ab289ca8a8ed7.html
The endocannabinoid system and associative learning and memory in zebrafish. (Germany) (click “PDF Reader” for full – 2015) https://docksci.com/the-endocannabinoid-system-and-associative-learning-and-memory-in-zebrafish_5a4c1ae2d64ab253c896ed1b.html
Excitatory drive from the subthalamic nucleus attenuates GABAergic transmission in the Substantia Nigra pars compacta via endocannabinoids (New Zealand) (link to PDF–2015) https://www.researchgate.net/publication/282912578_Excitatory_drive_from_the_Subthalamic_nucleus_attenuates_GABAergic_transmission_in_the_Substantia_Nigra_pars_compacta_via_endocannabinoids
Mechanisms of vasorelaxation induced by the cannabidiol analogue compound O-1602 in the rat small mesenteric artery. (Oman/ UK) (link to PDF– 2015) https://www.researchgate.net/publication/281166628_Mechanisms_of_vasorelaxation_induced_by_the_cannabidiol_analogue_compound_O-1602_in_the_rat_small_mesenteric_artery
Discovery of Rimonabant and its potential analogues as anti-TB drug candidates. (India) (link to PDF – 2015) https://www.researchgate.net/publication/276674897_Discovery_of_Rimonabant_and_its_potential_analogues_as_anti-TB_drug_candidates
N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte (China) (link to PDF–2015) https://www.researchgate.net/publication/281780501_N-
Oleoyl_glycine_a_lipoamino_acid_stimulates_adipogenesis_associated_with_activation_of_CBI_receptor_and_Akt_signaling_pathway_in_3T3-L1_adipocyte
Approaches for the development of drugs for treatment of obesity and metabolic syndrome. (Russia) (download – 2015) https://www.researchgate.net/publication/280301913_Approaches_for_the_Development_of_Drugs_for_Treatment_of_Obesity_and_Metabolic_Syndrome
The effects of endocannabinoid receptor agonist anandamide and antagonist rimonabant on opioid analgesia and tolerance in rats. (Turkey) (link to download–2015) http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=4378&category_id=119&option=com_virtuemart&vmcchk=1&Itemid=1
Modulatory effects by CB1 receptors on rat spinal locomotor networks after sustained application of agonists or antagonists. (Italy) (click “researchgate” for download–2015) https://scholar.google.com/scholar?q=Modulatory+effects+by+CB1+receptors+on+rat+spinal+locomotor+networks+after+sustained+application+of+agonists+or+antagonists&hl=en&as_sdt=0&as_vis=1&oi=scholart
Distinct roles of the endocannabinoids anandamide and 2-arachidonoylglycerol in social behavior and emotionality at different developmental ages in rats (Italy/Canada/Netherlands) (click “uunl” for download–2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Distinct+roles+of+the+endocannabinoids+anandamide+and+2-arachidonoylglycerol+in+social+behavior+and+emotionality+at+different+developmental+ages+in+rats%22&btnG
Inhibition of anandamide hydrolysis enhances noradrenergic and GABAergic transmission in the prefrontal cortex and basolateral amygdala of rats subjected to acute swim stress. (Italy) (click “academia” for download – 2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22nhibition+of+anandamide+hydrolysis+enhances+noradrenergic+and+GABAergic+transmission+in+the+prefrontal+cortex+and+basolateral+amygdala+of+rats+subjected+to+acute+swim+stress.&btnG
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Cannabinoid Hyperemesis Syndrome? Bring on the Hot Sauce. (USA) (article – 2015) http://journals.lww.com/em-news/blog/BreakingNews/Pages/post.aspx?PostID=183
Dissecting the cannabinergic control of behavior: The where matters. (France) (abst – 2015) https://www.semanticscholar.org/paper/Dissecting-the-cannabinergic-control-of-behavior%3A-Busquets-Garc%C3%ADa-Desprez/fa27ce2816ea3ce710f7457ec9e99b80b729dffc (video abst) https://www.youtube.com/watch?v=Lrq92aUv6eA
Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice. (USA) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0376871615000423
https://www.semanticscholar.org/paper/Effects-of-acute-and-repeated-dosing-of-the-on-in-Grim-Wiebelhaus/1cedf65d81412c5000951bd6088be69bf5f383ca
Spinal neuronal cannabinoid receptors mediate urodynamic effects of systemic fatty acid amide hydrolase (FAAH) inhibition in rats (Germany/Italy/Sweden) (abst–2015) https://www.semanticscholar.org/paper/Spinal-neuronal-cannabinoid-receptors-mediate-of-in-Fuellhase-Schreiber/b51a4ef67ea5b2fd72f077e6f48e4ed1e7202efe Rimonabant inhibits proliferation, collagen secretion and induces apoptosis in hepatic stellate cells. (China) (abst – 2015) https://www.ncbi.nlm.nih.gov/pubmed/25713910
Cannabinoid Receptor Agonists Modulate Calcium Channels in Rat Retinal Müller Cells. (China) (abst – 2015) https://www.sciencedirect.com/science/article/abs/pii/S0306452215010386
Effects of URB597 as an inhibitor of fatty acid amide hydrolase on WIN55, 212-2- induced learning and memory deficits in rats. (Iran) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0091305715000489
https://www.semanticscholar.org/paper/Effects-of-URB597-as-an-inhibitor-of-fatty-acid-on-Hasanein-Far/d9d5449b740294af0dfbd51ecacd5994e4f52dff
CB 1 Cannabinoid Receptor Agonist Inhibits Matrix Metalloproteinase Activity in Spinal Cord Injury: A Possible Mechanism of Improved Recovery. (USA/ China) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0304394015002979
Role of cannabinoidergic system on food intake in neonatal layer-type chicken. (Iran) (abst – 2015) https://link.springer.com/article/10.1007%2Fs11259-015-9636-3
https://www.semanticscholar.org/paper/Role-of-cannabinoidergic-system-on-food-intake-in-Alizadeh-Zendehdel/b7941f1836020b44b879e1639befa303e87460fa Inhibition of FAAH reduces nitroglycerin-induced migraine-like pain and trigeminal neuronal hyperactivity in mice. (Germany) (abst – 2015) https://www.sciencedirect.com/science/article/pii/S0924977X15001017
Interference with acute nausea and anticipatory nausea in rats by fatty acid amide hydrolase (FAAH) inhibition through a PPARα and CB1 receptor mechanism, respectively: a double dissociation. (Canada/ USA) (abst – 2015) https://www.semanticscholar.org/paper/Interference-with-acute-nausea-and-anticipatory-in-Rock-Limebeer/3c3222856ef09080a317239ed423343ae28530c3
Effects of Chronic Alcohol Exposure on the Modulation of Ischemia-Induced Glutamate Release via Cannabinoid Receptors in the Dorsal Hippocampus. (China) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26343919
Intracellular postsynaptic cannabinoid receptors link thyrotropin-releasing hormone receptors to TRPC-like channels in thalamic paraventricular nucleus neurons. (Canada) (abst – 2015) https://www.sciencedirect.com/science/article/abs/pii/S0306452215009227
Cannabinoid Receptors Modulate Rod-Cone Gap Junctional Coupling In The Day And Night (USA) (abst – 2015) http://iovs.arvojournals.org/article.aspx?articleid=2336723&resultClick=1
THC exerts neuroprotective effect in glutamate affected murine primary mesencephalic cultures and neuroblastoma N18TG2 cells. (Austria/ Egypt) (abst – 2015) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1565754
The disease-modifying effects of a Sativex-like combination of phytocannabinoids in mice with experimental autoimmune encephalomyelitis are preferentially due to Δ(9)- tetrahydrocannabinol acting through CB1 receptors (Spain) (abst–2015) http://www.msard-journal.com/article/S2211
-0348(15)00118-2/fulltext Endocannabinoid Inhibition Of Airway Sensory Nerve Depolarisation (UK) (abst–2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4114
Interaction Between Endocannabinoid and Opioidergic Systems Regulates Food Intake in Neonatal Chicken (Iran) (abst–2015) http://link.springer.com/article/10.1007/s10989-015-9457-9
Cannabinoid Ligands and Alcohol Addiction: A Promising Therapeutic Tool or a Humbug? (Poland) (full – 2016) http://link.springer.com/article/10.1007/s12640-015-9555-7/fulltext.html
CB1 receptor blockade counters age-induced insulin resistance and metabolic dysfunction. (UK/ China) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783351/
Effects of Cannabinoid Exposure during Adolescence on the Conditioned Rewarding Effects of WIN 55212-2 and Cocaine in Mice: Influence of the Novelty-Seeking Trait. (Spain) (full – 2016) http://www.hindawi.com/journals/np/2016/6481862/
Transient increase of interleukin-1β after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling. (China/ Canada) (full – 2016) http://www.nature.com/articles/srep21931
Behavioral Characterization of the Effects of Cannabis Smoke and Anandamide in Rats. (USA) (full – 2016) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153327
Dissociating the role of endocannabinoids in the pleasurable and motivational properties of social play behaviour in rats. (Netherlands) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914428/
Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679742/
Medullary Endocannabinoids Contribute to the Differential Resting Baroreflex Sensitivity in Rats with Altered Brain Renin-Angiotensin System Expression. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899471/
Endocannabinoids in Feeding Behavior and Energy Homeostasis (USA) (full–2016) http://themedicalbiochemistrypage.org/endocannabinoids.php
The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927043/
Cannabidiol, among Other Cannabinoid Drugs, Modulates Prepulse Inhibition of Startle in the SHR Animal Model: Implications for Schizophrenia Pharmacotherapy. (Brazil) (full – 2016) http://journal.frontiersin.org/article/10.3389/fphar.2016.00303/full
Regional Influence of Cannabinoid CB1 Receptors in the Regulation of Ethanol Self- Administration by Wistar Rats. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152943/
Attenuation of Cocaine-Induced Conditioned Place Preference and Motor Activity via Cannabinoid CB2 Receptor Agonism and CB1 Receptor Antagonism in Rats. (Greece/ USA) (full – 2016) http://ijnp.oxfordjournals.org/content/early/2016/12/19/ijnp.pyw102.long
Interacting Cannabinoid and Opioid Receptors in the Nucleus Accumbens Core Control Adolescent Social Play. (France/ Italy/ Netherlands) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110529/
Ontogeny of sensorimotor gating and short-term memory processing throughout the adolescent period in rats. (Germany) (full – 2016) http://www.sciencedirect.com/science/article/pii/S1878929316300639
Possible Therapeutic Doses of Cannabinoid Type 1 Receptor Antagonist Reverses Key Alterations in Fragile X Syndrome Mouse Model. (Spain) (full – 2016) http://www.mdpi.com/2073-4425/7/9/56/htm
Turning Up the Heat on Endocannabinoid Signaling. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106110/
Endocannabinoid System: the Direct and Indirect Involvement in the Memory and Learning Processes—a Short Review. (Poland) (full – 2016) http://link.springer.com/article/10.1007%2Fs12035
Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome. (Israel/ USA/ Canada) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123200/
Self-administration of the anandamide transport inhibitor AM404 by squirrel monkeys. (USA/ Italy) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846479/
Blockade of Nicotine and Cannabinoid Reinforcement and Relapse by a Cannabinoid CB1-Receptor Neutral Antagonist AM4113 and Inverse Agonist Rimonabant in Squirrel Monkeys. (Canada/ USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946059/
Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive Behavior during Forced Abstinence from Alcohol Drinking. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908652/
Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices. (USA/ Israel) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848126/
Cannabinoid type 1 receptor antagonism ameliorates harmaline-induced essential tremor in rat. (Iran/ UK) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071561/
Cannabidiol Modulates Fear Memory Formation through Interactions with Serotonergic Transmission in the Mesolimbic System. (Canada) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061893/
Enhanced discriminative stimulus effects of Δ9-THC in the presence of cannabidiol and 8-OH-DPAT in rhesus monkeys. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947395/
Inhaled delivery of Δ9-tetrahydrocannabinol (THC) to rats by e-cigarette vapor technology. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970926/
The CB1 antagonist, SR141716A, is protective in permanent photothrombotic cerebral ischemia. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002388/
Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959103/
Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096949/
Involvement of Central Endothelin ETA and Cannabinoid CB1 Receptors and Arginine Vasopressin Release in Sepsis Induced by Cecal Ligation and Puncture in Rats. (Brazil) (full – 2016) https://journals.lww.com/shockjournal/FullText/2016/09000/Involvement_of_Central_Endothelin_ETA_and.10.aspx
ENDOCANNABINOID SYSTEM: A multi-facet therapeutic target. (India) (link to PDF–2016) https://www.researchgate.net/publication/301533431_Endocannabinoid_System_A_Multi-Facet_Therapeutic_Target
Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin. (Portugal/ USA) (link to PDF – 2016) https://www.researchgate.net/publication/303358549_Hierarchical_glucocorticoid-
endocannabinoid_interplay_regulates_the_activation_of_the_nucleus_accumbens_by_insulin Revealing the role of the endocannabinoid system modulators, SR141716A, URB597 and VDM-11, in sleep homeostasis. (Mexico/ Brazil/ Portugal/ Lithuania/ China) (link to PDF – 2016) https://www.researchgate.net/publication/309158406_Revealing_the_role_of_the_endocannabinoid_system_modulators_SR141716A_URB597_and_VDM-11_in_sleep_homeostasis
Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome. (UK/ Qatar) (link to PDF – 2016) https://www.researchgate.net/publication/308486956_Endocannabinoid_receptor_blockade_increases_vascular_endothelial_growth_factor_and_inflammatory_markers_in_obese_women_with_polycystic_ovary_syndrome
The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric oxide-cGMP- dependent vasorelaxant. (Oman) (link to PDF – 2016) https://www.researchgate.net/publication/310816046_The_endogenous_lipid_N-arachidonoyl_glycine_is_hypotensive_and_nitric_oxide-cGMP-dependent_vasorelaxant
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ALCOHOL DEPENDENCE–NEUROBIOLOGY AND TREATMENT. (Poland) (link to PDF–2016) https://www.researchgate.net/publication/303138029_Alcohol_dependence_-_Neurobiology_and_treatment
Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth. (USA) (ignore error message) (download – 2016) http://www.jbc.org/content/early/2016/02/21/jbc.M115.707836.long
Involvement of TRPV1 in the Olfactory Bulb in Rimonabant-Induced Olfactory Discrimination Deficit. (China) (link to full – 2016) https://pubmed.ncbi.nlm.nih.gov/26875559/
CB1 Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal. (Spain/ Italy/ France) (download – 2016) https://repositori.upf.edu/bitstream/handle/10230/30842/Saravia_BioPsy_CB1.pdf?sequence=1
Cannabinoid Receptor Interacting Protein (CRIP1a) suppresses agonist-driven CB1 receptor internalization, and regulates receptor replenishment in an agonist-biased manner. (link to download – 2016) Cannabinoid receptor interacting protein suppresses agonist … Adolescent social rejection alters pain processing in a CB1 receptor dependent manner. (Germany) (click “daneshyari” for download – 2016) https://scholar.google.com/scholar?q=Adolescent+social+rejection+alters+pain+processing+in+a+CB1+receptor+dependent+manner&hl=en&as_sdt=0&as_vis=1&oi=scholart
Effect of synthetic cannabinoids on spontaneous neuronal activity: Evaluation using Ca2+ spiking and multi-electrode arrays. (Canada) (click “open access” then “ncrpublicationscanadaca” for download – 2016) https://www.semanticscholar.org/paper/Effect-of-synthetic-cannabinoids-on-spontaneous-and-Tauskela-Comas/2932e8404f4116dc42820c86d36646a37b1ccdc0 Attenuation of cue-induced reinstatement of nicotine seeking by URB597 through cannabinoid CB1 receptor in rats (Canada/France/Egypt/USA) (click “archivesouvertesfr” for download–2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Attenuation+of+cue-induced+reinstatement+of+nicotine+seeking+by+URB597+through+cannabinoid+CB1+receptor+in+rats&btnG
Harvesting Benefits from Cannabinoids. (USA) (article – 2016) http://www.cell.com/cell/fulltext/S0092-8674(16)31675-0
Investigation of receptor binding and functional characteristics of hemopressin(1-7). (abst – 2016) (Hungary) http://www.neuropeptidesjournal.com/article/S0143-4179(16)00020-2/abstract
https://www.semanticscholar.org/paper/Investigation-of-receptor-binding-and-functional-of-Dvor%C3%A1csk%C3%B3-T%C3%B6mb%C3%B6ly/be7a304375ad3a939d588c75306315e79d3e24b0 Encapsulation of cannabinoid drugs in nanostructured lipid carriers. (Italy/ Germany) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26952905
Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6- hydroxydopamine lesioned rat brains. (Australia/ China) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27155397
CB1 Receptor Antagonism Prevents Long-Term Hyperexcitability after Head Injury by of Dynorphin-KOR System and mGluR5 in Rat Hippocampus. (China) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S0006899316304243
A High Efficacy Cannabinergic Ligand (AM4054) used as a Discriminative Stimulus: Generalization to other Adamantyl Analogs and Δ9-THC in Rats. (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0091305716301022
Antagonism of cannabinoid receptor 1 attenuates the anti-inflammatory effects of electroacupuncture in a rodent model of migraine. (China) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27834685
A dual inhibitor of FAAH and TRPV1 channels shows dose-dependent effect on depression-like behaviour in rats. (Denmark/ Brazil) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27938441
Rimonabant improves metabolic parameters partially attributed to restoration of high voltage-activated Ca2+ channels in skeletal muscle in HFD-fed mice. (China) (full in English – 2017) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000600602&lng=en&nrm=iso&tlng=en
(full – links to many languages – 2017) http://www.scielo.br/scieloOrg/php/translate.php?pid=S0100-
879X2017000600602&caller=www.scielo.br&lang=en&tlang=en&script=sci_arttext Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. (Netherlands/ Switzerland/ Germany/ USA/ Italy/ New Zealand/ Australia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216056/
Involvement of Cannabinoid Signaling in Vincristine-Induced Gastrointestinal Dysmotility in the Rat. (Spain) (full – 2017) http://journal.frontiersin.org/article/10.3389/fphar.2017.00037/full
The role of exercise training and the endocannabinoid system in atherosclerotic plaque burden and composition in Apo-E-deficient mice. (Greece) (full – 2017) http://www.sciencedirect.com/science/article/pii/S1109966616302949
Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. (USA) (full – 2017) http://www.nature.com/articles/ncomms14782
Cannabinoid CB2 Receptors are Involved in the Protection of RAW264.7 Macrophages Against the Oxidative Stress: An in Vitro Study. (Italy) (full – 2017) http://www.ejh.it/index.php/ejh/article/view/2749/2659
Cannabinoid Modulation of Memory Consolidation in Rats: Beyond the Role of Cannabinoid Receptor Subtype 1. (Italy) (full – 2017) http://journal.frontiersin.org/article/10.3389/fphar.2017.00200/full
Endocannabinoid receptor blockade reduces alanine aminotransferase in polycystic ovary syndrome independent of weight loss. (UK/ Qatar) (full – 2017) https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-017-0194-2
Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. (USA/ Israel) (full – 2017) http://www.sciencedirect.com/science/article/pii/S1044743117300830
Mice expressing a “hyper-sensitive” form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398885/
Targeting the Endocannabinoid/CB1 Receptor System For Treating Major Depression Through Antidepressant Activities of Curcumin and Dexanabinol-Loaded Solid Lipid Nanoparticles. (China) (full – 2017) https://www.karger.com/Article/FullText/480001
Cannabinoid Receptor Signaling in Central Regulation of Feeding Behavior: A Mini- Review. (Germany) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442223/
Anti-Inflammatory Activity in Colon Models Is Derived from Δ9- Tetrahydrocannabinolic Acid That Interacts with Additional Compounds in Cannabis Extracts. (Israel) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627671/
Pharmacological inhibition of cannabinoid receptor 1 stimulates gastric release of nesfatin-1 via the mTOR pathway. (Spain) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643265/
MECHANISMS IN ENDOCRINOLOGY: Endocannabinoids and metabolism: past, present and future. (France) (full – 2017) https://eje.bioscientifica.com/view/journals/eje/176/6/R309.xml
Kinetics of human Cannabinoid 1 (CB1) receptor antagonists: structure-kinetics relationships (SKRs) and implications for insurmountable antagonism. (full – 2017) http://www.sciencedirect.com/science/article/pii/S0006295217306457?via%3Dihub
Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688117/
Regulation of noradrenergic and serotonergic systems by cannabinoids: relevance to cannabinoid-induced effects. (Spain) (full – 2017) http://www.sciencedirect.com/science/article/pii/S0024320517306069?via%3Dihub
Suppression of STAT3 Signaling by Δ9-Tetrahydrocannabinol (THC) Induces Trophoblast Dysfunction. (China) (full – 2017) https://www.karger.com/Article/FullText/477603
Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396529/
A cannabinoid receptor antagonist attenuates ghrelin-induced activation of the mesolimbic dopamine system in mice. (Sweden) (full – 2017) https://www.sciencedirect.com/science/article/pii/S0031938417304274?via%3Dihub
The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality? (France) (full – 2017) https://www.frontiersin.org/articles/10.3389/fnsyn.2017.00015/full
Cannabinoids Regulate the Diameter of Pericyte-Containing Retinal Capillaries in Rats. (China) (full – 2017) https://www.karger.com/Article/FullText/484193
Acetaminophen Relieves Inflammatory Pain Through CB1 Cannabinoid Receptors in the Rostral Ventromedial Medulla. (Switzerland/ Hungary) (full – 2017) http://www.jneurosci.org/content/38/2/322.long
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer. (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601949/
Human serum albumin: A modulator of cannabinoid drugs. (Italy) (full – 2017) https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/iub.1682
Synthetic cannabinoids found in “spice” products alter body temperature and cardiovascular parameters in conscious male rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599362/
Intra-accumbal blockade of endocannabinoid CB1 receptors impairs learning but not retention of conditioned relief. (Germany) (full – 2017) https://kundoc.com/pdf-intra-accumbal-blockade-of-endocannabinoid-cb1-receptors-impairs-learning-but-no.html
Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771234/
Mouse retinal ganglion cell signalling is dynamically modulated through parallel anterograde activation of cannabinoid and vanilloid pathways. (USA/ Japan) (full – 2017) https://physoc.onlinelibrary.wiley.com/doi/full/10
.1113/JP274562 The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice. (USA/ Turkey/ Saudi Arabia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558428/
Pooled analysis of three randomized, double-blind, placebo controlled trials with rimonabant for smoking cessation. (USA/ France) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912319/
Post-sensitization treatment with rimonabant blocks the expression of cocaine-induced behavioral sensitization and c-Fos protein in mice. (Brazil) (full – 2017) http://www.sciencedirect.com/science/article/pii/S0091305717301995?via%3Dihub
Activation of cannabinoid receptor 1 is involved in protection against mitochondrial dysfunction and cerebral ischaemic tolerance induced by isoflurane preconditioning (China) (full–2017) https://bjanaesthesia.org/article/S0007-0912(17)54150-1/fulltext
Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse (full-2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554085/
Context-dependent effects of rimonabant on ethanol-induced conditioned place preference in female mice (Brazil/USA) (full–2017) https://www.sciencedirect.com/science/article/pii/S0376871617304052
Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence (USA/UK) (full–2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758437/
Cannabinoid-1 receptor neutral antagonist reduces binge-like alcohol consumption and alcohol-induced accumbal dopaminergic signaling. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820178/
Chronic CB1 cannabinoid receptor antagonism persistently increases dendritic spine densities in brain regions important to zebra finch vocal learning and production in an antidepressant-sensitive manner. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661891/
A behavioral and pharmacological characterization of palatable diet alternation in mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911178/
Apparent CB1 receptor rimonabant affinity estimates: combination with THC and synthetic cannabinoids in the mouse in vivo triad model. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478909/
The cannabinoid CB2 agonist GW405833 suppresses inflammatory and neuropathic pain through a CB1 mechanism that is independent of CB2 receptors in mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502377/
Antinociceptive effects of JWH015 in female and male rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849479/
An endocannabinoid uptake inhibitor from black pepper exerts pronounced anti- inflammatory effects in mice. (Mexico/ Switzerland) (link to PDF– 2017) http://pubs.acs.org/doi/abs/10.1021/acs.jafc.7b02979
Apparent affinity estimates and reversal of the effects of synthetic cannabinoids AM- 2201, CP-47,497, JWH-122, and JWH-250 by rimonabant in rhesus monkeys (USA) (link to PDF–2017) http://jpet.aspetjournals.org/content/early/2017/05/22/jpet.117.240572.long
Exercise versus targeting of endocannabinoid system for atheromatic plaque stabilization. Opposing or complementary roles? (Greece) (link to PDF – 2017) https://www.researchgate.net/publication/316356545_Exercise_versus_targeting_of_endocannabinoid_system_for_atheromatic_plaque_stabilization_Opposing_or_complementary_roles
Anti-migraine effect of ∆9-tetrahydrocannabinol in the female rat (USA) (link to PDF–2017) https://www.researchgate.net/publication/320687020_Anti-migraine_effect_of_9_-tetrahydrocannabinol_in_the_female_rat
Activation of CaMKKβ/AMPKα pathway by 2-AG in human platelets (Italy) (link to PDF–2017) https://www.researchgate.net/publication/318050607_Activation_of_CaMKKbAMPKa_pathway_by_2-AG_in_human_platelets
The endocannabinoid system as a target for addiction treatment: Trials and tribulations (Canada/USA) (link to PDF–2017) https://www.researchgate.net/publication/317252828_The_endocannabinoid_system_as_a_target_for_addiction_treatment_Trials_and_tribulations
Targeting fatty acid amide hydrolase and transient receptor potential vanilloid-1 simultaneously to modulate colonic motility and visceral sensation in the mouse: A pharmacological intervention with N-arachidonoyl-serotonin (AA-5-HT) (Canada/USA/Poland/Italy/Germany/Belgium/France) (link to PDF–2017) https://www.researchgate.net/publication/318378715_Targeting_fatty_acid_amide_hydrolase_and_transient_receptor_potential_vanilloid1_simultaneously_to_modulate_colonic_motility_and_visceral_sensation_in_the_mouse_A_pharmacological_intervention_with_ N-
2-Arachidonoylglycerol as a possible treatment for anorexia nervosa in animal model in mice (Israel) (link to PDF–2017) https://www.researchgate.net/publication/317497328_2-Arachidonoylglycerol_as_a_possible_treatment_for_anorexia_nervosa_in_animal_model_in_mice
Contribution of CB1Rs in anxiety-related behaviors but not locomotor deficits induced by methamphetamine. (Iran) (link to PDF – 2017) https://www.researchgate.net/publication/321739457_Contribution_of_CB1Rs_in_anxiety-related_behaviors_but_not_locomotor_deficits_induced_by_methamphetamine Effects of 7 days of treatment with the cannabinoid type 1 receptor antagonist, rimonabant, on emotional processing. (UK) (link to download – 2017) thcint.com Protective effect of rimonabant, a canabinoid receptor 1 antagonist on nonalcoholic fatty liver disease in a rat model by modulating the hepatic expression of activin A and follistatin. (Egypt) (click “View PDF for download – 2017) https://www.semanticscholar.org/paper/Protective-effect-of-rimonabant%2C-a-canabinoid-1-on-Hussien-El-Kerdasy/5011a3347c29a1f634cf76ef395517895926d3b6 Polyunsaturated Fatty Acids Differentially Modulate Cell Proliferation and Endocannabinoid System in Two Human Cancer Lines. (Argentina/ USA) (click “researchgate” for download – 2017) https://scholar.google.com/scholar?q=Polyunsaturated+Fatty+Acids+Differentially+Modulate+Cell+Proliferation+and+Endocannabinoid+System+in+Two+Human+Cancer+Lines.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Analysis of Natural Product Regulation of Cannabinoid Receptors in the treatment of Human Disease. (USA/ Jamaica) (click “researchgate” for download – 2017) https://scholar.google.com/scholar?q=Analysis+of+natural+product+regulation+of+cannabinoid+receptors+in+the+treatment+of+human+disease.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Prospects for the Use of Cannabinoid Receptor Ligands for the Treatment of Metabolic Syndrome and Atherosclerosis: Analysis of Experimental and Clinical Data. (Russia) (abst, link to full PDF in Russian – 2017) https://www.semanticscholar.org/paper/%5BProspects-for-the-Use-of-Cannabinoid-Receptor-for-Maslov-Karpov/d01b44c406ef1941709b0c18e10b314adbec6778 Cannabidiol upregulates melanogenesis through CB1 dependent pathway by activating p38 MAPK and p42/44 MAPK. (Republic of Korea) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0009279716304343?via%3Dihub
Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons. (USA/ Scotland) (abst – 2017) https://pubs.acs.org/doi/10.1021/acschemneuro.6b00310
Extinction of avoidance behavior by safety learning depends on endocannabinoid signaling in the hippocampus (Czech Republic/Germany/Italy) (abst–2017) https://www.sciencedirect.com/science/article/abs/pii/S0022395616308469?via%3Dihub
Rimonabant, a selective cannabinoid1 receptor antagonist, protects against light-induced retinal degeneration in vitro and in vivo. (Japan) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0014299917301887
The effect of cannabinoid receptor 1 blockade on hepatic free fatty acid profile in mice with nonalcoholic fatty liver disease (Serbia) (abst–2017) https://www.sciencedirect.com/science/article/pii/S0009308417300063
https://www.semanticscholar.org/paper/The-effect-of-cannabinoid-receptor-1-blockade-on-in-Jorga%C4%8Devi%C4%87-Vu%C4%8Devi%C4%87/27bb0e2f9a5eec2d03605983102fd9dd1aa73f30
Metabolic side effects induced by olanzapine treatment are neutralized by CB1 receptor antagonist compounds co-administration in female rats. (Italy) (abst – 2017) https://www.semanticscholar.org/paper/Metabolic-side-effects-induced-by-olanzapine-are-by-Lazzari-Serra/8a2e837c996b4c6ae703b5b96a6f212d51aee818
A synthetic cannabinoid JWH-210 reduces lymphoid organ weights and T-cell activator levels in mice via CB2 receptors. (Republic of Korea) (abst – 2017) https://link.springer.com/article/10.1007/s00210-017-1418-8
https://www.semanticscholar.org/paper/A-synthetic-cannabinoid-JWH-210-reduces-lymphoid-in-Gu-Lee/2dadde42d082cf11e42188369e41402dbdd9a8aa
Re-visiting the Endocannabinoid System and Its Therapeutic Potential in Obesity and Associated Diseases. (USA) (abst – 2017) https://link.springer.com/article/10.1007%2Fs11892-017-0924-x
Enhanced anandamide signaling reduces flight behavior elicited by an approaching robo- beetle. (Germany) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0028390817304276?via%3Dihub
Neuroprotective effect of cannabinoid receptor 1 antagonist in the MNU-induced retinal degeneration model. (China) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0014483517305080
https://www.semanticscholar.org/paper/Neuroprotective-effect-of-cannabinoid-receptor-1-in-Chen-
Luo/3fa9903c6d534c0e086e7ad784a8056b34cb1693 Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids (Italy/Netherlands) (full–2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758598/
Endocannabinoids in Body Weight Control. (Germany) (full – 2018) http://www.mdpi.com/1424-8247/11/2/55/htm
Effects of repeated long-term psychosocial stress and acute cannabinoid exposure on mouse corticostriatal circuitries: Implications for neuropsychiatric disorders (Germany/Spain/Italy) (full–2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969305/
Orosensory Detection of Dietary Fatty Acids Is Altered in CB1R−/− Mice. (France) (full – 2018) https://www.mdpi.com/2072-6643/10/10/1347/htm
Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy. (Italy/ Germany/ USA/ Canada) (full – 2018) https://www.nature.com/articles/s41467-018-06267-1
Examination of the effects of cannabinoid ligands on decision making in a rat gambling task (Netherlands/Canada) (full–2018) https://www.sciencedirect.com/science/article/pii/S0091305717307050
Cannabinoid receptor-1 signaling contributions to sign-tracking and conditioned reinforcement in rats. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344029/
Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404969/
Acute ethanol inhibition of adult hippocampal neurogenesis involves CB1 cannabinoid receptor signaling. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042509/
MODULATION OF MEAN ARTERIAL PRESSURE AND DIURESIS BY RENOMEDULLARY INFUSION OF A SELECTIVE INHIBITOR OF FATTY ACID AMIDE HYDROLASE. (USA) (full – 2018) https://www.physiology.org/doi/full/10.1152/ajprenal.00090.2018?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-
2003&rfr_id=ori%3Arid%3Acrossref.org Cannabinoid agonist administration within the cerebellar cortex impairs motor learning. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311437/
Involvement of the CB2 cannabinoid receptor in cell growth inhibition and G0/G1 cell cycle arrest via the cannabinoid agonist WIN 55,212–2 in renal cell carcinoma. (Poland/ Canada) (full – 2018) https://bmccancer.biomedcentral.com/articles/10.1186/s12885-018-4496-1
Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397651/
Melatonin attenuates Δ9-tetrahydrocannabinol-induced reduction in rat sperm motility and kinematics in-vitro. (Rwanda/ Nigeria) (link to PDF – 2018) https://www.researchgate.net/publication/323198133_Melatonin_attenuates_D_9_-tetrahydrocannabinol-induced_reduction_in_rat_sperm_motility_and_kinematics_in-vitro
Computational investigation on the binding modes of Rimonabant analogues with CB1 and CB2. (link to PDF – 2018) https://www.researchgate.net/publication/325364042_Computational_investigation_on_the_binding_modes_of_Rimonabant_analogs_with_CB1_and_CB2
Effect of cannabidiolic acid and ∆9-tetrahydrocannabinol on carrageenan-induced hyperalgesia and edema in a rodent model of inflammatory pain (Canada) (link to PDF–2018) https://www.researchgate.net/publication/327705598_Effect_of_cannabidiolic_acid_and_9-tetrahydrocannabinol_on_carrageenan-induced_hyperalgesia_and_edema_in_a_rodent_model_of_inflammatory_pain Rimonabant, a potent CB1 cannabinoid receptor antagonist, is a Gαi/o protein inhibitor. (Italy Switzerland) (link to download – 2018) https://www.researchgate.net/publication/322989092_Rimonabant_a_potent_CB1_cannabinoid_receptor_antagonist_is_a_Gaio_protein_inhibitor
Role of the endocannabinoid system in drug addiction. (Spain) (link to download–2018) aghealth.net
Role of the endogenous cannabinoid receptor 1 in brain injury induced by chronic intermittent hypoxia in rats. (China) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29264962
Single and combined effects of plant-derived (THC, CBD) and synthetic (WIN-55,212) cannabinoids on cognition and cannabinoid-associated withdrawal signs in mice (USA) (abst–2018) https://www.ncbi.nlm.nih.gov/pubmed/29338068
The quest for endothelial atypical cannabinoid receptor: BKCa channels act as cellular sensors for cannabinoids in in vitro and in situ endothelial cells (abst–2018) https://www.ncbi.nlm.nih.gov/pubmed/29355732
The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis. (Portugal) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0378427418300377
The inhibition of CB1 receptor accelerates the onset and development of EAE possibly by regulating microglia/macrophages polarization. (China) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0165572817304678
The effects of antipsychotics on the density of cannabinoid receptors in selected brain regions of male and female adolescent juvenile rats. (Australia) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0165178117315883
https://www.semanticscholar.org/paper/The-effects-of-antipsychotics-on-the-density-of-in-Lian-Deng/bf9af9cd9c04e19a93bb4b0e25a1082d364918a9
Effect of CB1 Ligands on Neurogenic and Myogenic Contractile Responses in the Guinea-Pig Ileum. (Austria) (abst – 2018) https://www.semanticscholar.org/paper/Effect-of-CB1-Ligands-on-Neurogenic-and-Myogenic-in-Donnerer-Liebmann/f0bf75a2b4838b55aa038c707a34e2af223a466c Cannabinoid receptor type 1 in the brain regulates the affective component of visceral pain in mice. (Germany) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0306452218303919
Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin. (USA) (abst – 2018) https://www.nature.com/articles/s41401-018-0073-z
https://www.semanticscholar.org/paper/Developmental-and-behavioral-effects-in-neonatal-of-Perchuk-Bierbower/1c51c30dea30cd1fefa6bf2701d83f80fe594c11
Role of the Endocannabinoid System in the Pathophysiology of Schizophrenia: Implications for Pharmacological Intervention. (Germany/ Australia) (abst – 2018) https://link.springer.com/article/10.1007%2Fs40263-018-0539-z
https://www.semanticscholar.org/paper/Role-of-the-Endocannabinoid-System-in-the-of-for-Leweke-Mueller/fe7f478e85a4f0fa37d1389d5ead3b2df83455d7
Opposing roles of type-1 and type-2 cannabinoid receptors in cocaine stimulant and rewarding effects. (Brazil/ Ireland) (abst – 2018) https://www.semanticscholar.org/paper/Opposing-roles-of-CB1-and-CB2-cannabinoid-receptors-Gobira-Oliveira/72069691b0ba5f96aa6c7d7c4cf2035231b44509
Astrocytic Mechanisms Involving Kynurenic Acid Control Δ9-Tetrahydrocannabinol- Induced Increases in Glutamate Release in Brain Reward-Processing Areas (USA/Italy) (abst–2018) https://www.semanticscholar.org/paper/Astrocytic-Mechanisms-Involving-Kynurenic-Acid-in-Secci-Mascia/dffb4ea792f2f7265f3a5e95b3cedf4fca4485ba
Conditioned gaping produced by high dose Δ9-tetrahydracannabinol: Dysregulation of the hypothalamic endocannabinoid system. (Canada) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0028390818305987?via%3Dihub
https://www.semanticscholar.org/paper/Conditioned-gaping-produced-by-high-dose-of-the-DeVuono-Hrelja/a65e1429a42f6b08f8ff8d5aaea39093ec4fb36a
Neuronal nicotinic acetylcholine receptors mediate ∆9 -THC dependence: Mouse and human studies. (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/30378732
Enhancing effects of acute exposure to cannabis smoke on working memory performance. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563837/
∆9-Tetrahydrocannabinol, a major marijuana component, enhances the anesthetic effect of pentobarbital through the CB1 receptor. (Japan) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314990/
Cannabis: From a Plant That Modulates Feeding Behaviors toward Developing Selective Inhibitors of the Peripheral Endocannabinoid System for the Treatment of Obesity and Metabolic Syndrome. (Israel) (full – 2019) https://www.mdpi.com/2072-6651/11/5/275/htm
Tolerance and dependence to Δ9-tetrahydrocannabinol in rhesus monkeys: Activity assessments. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413903/
Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis. (Germany) (full – 2019) https://www.mdpi.com/1422-0067/20/10/2516/htm
Modulation of NMDA-Mediated Clock Resetting in the Suprachiasmatic Nuclei of mPer2 Luc Mouse by Endocannabinoids. (Czech Republic) (full – 2019) https://www.frontiersin.org/articles/10.3389/fphys.2019.00361/full
Cannabinoid receptor-1 antagonism: a new perspective on treating a murine schistosomal liver fibrosis model. (Egypt) (full – 2019) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100338&lng=en&nrm=iso&tlng=en
Bone Anabolic Response in the Calvaria Following Mild Traumatic Brain Injury is Mediated by the Cannabinoid-1 Receptor. (Israel/ USA) (full – 2019) https://www.nature.com/articles/s41598-019-51720-w
Brain permeant and impermeant inhibitors of fatty-acid amide hydrolase suppress the development and maintenance of paclitaxel-induced neuropathic pain without producing tolerance or physical dependence in vivo and synergize with paclitaxel to reduce tumor cell line viability in vitro. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878658/
Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay. (China/ UK) (full – 2019) https://www.sciencedirect.com/science/article/pii/S0378874119315569
Endocannabinoids and Fear-Related Behavior in Mice Selectively Bred for High or Low Alcohol Preference. (USA) (full – 2019) https://www.mdpi.com/2076-3425/9/10/254/htm
Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders. (USA) (click “researchgate” for download – 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Potential+of+Cannabinoid+Receptor+Ligands+as+Treatment+for+Substance+Use+Disorders%22&btnG
Gastrointestinal Adverse Events of Cannabinoid 1 Receptor Inverse Agonists suggest their Potential Use in Irritable Bowel Syndrome with Constipation: A Systematic Review and Meta-Analysis. (Poland/ Germany) (full – 2019) https://www.jgld.ro/jgld/index.php/jgld/article/view/265/167
CB1 positive allosteric modulation attenuates Δ9-THC withdrawal and NSAID-induced gastric inflammation. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405226/
Ethanol and cannabinoids interact to alter behavior in a zebrafish fetal alcohol spectrum disorder model. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30648819
Chronic aerobic exercise: Lack of effect on brain CB1 receptor levels in adult rats. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S002432051930414X?via%3Dihub
Role of the endocannabinoid and endovanilloid systems in an animal model of schizophrenia-related emotional processing/cognitive deficit. (Brazil) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0028390819301649?via%3Dihub
Targeting CB1 and GPR55 Endocannabinoid Receptors as a Potential Neuroprotective Approach for Parkinson’s Disease. (Spain) (abst – 2019) https://link.springer.com/article/10.1007%2Fs12035-019-1495-4
Novel object recognition memory in REM sleep-deprived rats: role of the cannabinoid CB1 receptor. (Iran) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31711896
Δ9-THC and related cannabinoids suppress substance P- induced neurokinin NK1- receptor-mediated vomiting via activation of cannabinoid CB1 receptor. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0014299919307587?via%3Dihub
The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling. (UK) (full – 2020) https://link.springer.com/article/10.1007%2Fs00018-019-03433-6
Cannabinoid Modulation of Food-Cocaine Choice in Male Rhesus Monkeys (USA) (link to PDF-2020) http://jpet.aspetjournals.org/content/early/2020/01/15/jpet.119.263707.long
Dietary intake of polyunsaturated fatty acids alleviates cognition deficits and depression- like behaviour via cannabinoid system in sleep deprivation rats. (China) (abst – 2020) https://www.sciencedirect.com/science/article/pii/S0166432819317218
R(+)-METHANANANDAMIDE/AM-356
Energetic Metabolism and Human Sperm Motility: Impact of CB1 Receptor Activation. (full – 2010) http://endo.endojournals.org/content/151/12/5882.full
Anandamide extends platelets survival through CB(1)-dependent Akt signaling. (abst – 2010) https://www.semanticscholar.org/paper/Anandamide-extends-platelets-survival-through-Akt-Catani-
Gasperi/ed73f63f8a88a1d8cb64d9353c401a7223e5b53d Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037938
Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156972/
The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease. (full – 2011) http://www.nature.com/mi/journal/v4/n5/full/mi201118a.html
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. (click “rocmexico” for download–2011) https://scholar.google.com/scholar?q=Cannabidiol+inhibits+lung+cancer+cell+invasion+and+metastasis+via+intercellular+adhesion+molecule-1.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro. (abst – 2011) https://www.semanticscholar.org/paper/Effects-of-Cannabinoid-Agonists-on-Sheep-Sphincter-Sara%C3%A7-Durmus/b1de7d0e19cef42524011de7b7d85b0c7c4eece4 Anandamide Induces Sperm Release from Oviductal Epithelia through Nitric Oxide Pathway in Bovines. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281848/?tool=pubmed
Uncovering a role for endocannabinoid signaling in autophagy in preimplantation mouse embryos. (full – 2012) http://molehr.oxfordjournals.org/content/19/2/93.full
Neonatal DSP-4 Treatment Modifies Antinociceptive Effects of the CB(1) Receptor Agonist Methanandamide in Adult Rats. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526738/
GPR18 in microglia: implications for the CNS and endocannabinoid system signaling. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525861/
Long-term treatment with methanandamide attenuates LPS-induced periodontitis in rats (full–2012) https://www.academia.edu/19292978/Long-term_treatment_with_methanandamide_attenuates_LPS-induced_periodontitis_in_rats
Contrasting effects of different cannabinoid receptor ligands on mouse ingestive behavior. (abst – 2012) http://www.unboundmedicine.com/medline/ebm/record/22772336/abstract/Contrasting_effects_of_different_cannabinoid_receptor_ligands_on_mouse_ingestive_behaviour_
Activation of Type 1 Cannabinoid Receptor (CB1R) Promotes Neurogenesis in Murine Subventricular Zone Cell Cultures. (full – 2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063529
Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia. (full – 2013) https://academic.oup.com/humrep/article/28/8/2058/660793
Diuretic effects of cannabinoids. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533417/
Endocannabinoids as markers of sperm quality: hot spots. (full – 2013) http://www.frontiersin.org/Journal/10.3389/fendo.2013.00169/full
Diuretic effects of cannabinoid agonists in mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872476/
Role of cannabinoid and vanilloid receptors in invasion of human breast carcinoma cells. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23394450
Repositioning therapy for thyroid cancer: new insights on established medications. (full – 2014) http://erc.endocrinology-journals.org/content/21/3/R183.long
Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis. (full – 2014) http://www.ijbs.com/v10p0466.htm
2012 Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective. (USA) (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064474/
Identification of a Pharmacological Target for Genioglossus Reactivation throughout Sleep. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902869/
Ligand Activation of Cannabinoid Receptors Attenuates Hypertrophy of Neonatal Rat Cardiomyocytes. (full – 2014) https://journals.lww.com/cardiovascularpharm/FullText/2014/11000/Ligand_Activation_of_Cannabinoid_Receptors.4.aspx
Cannabinoids inhibit angiogenic capacities of Endothelial cells via release of Tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0006295214003608
CANNABINOIDS INCREASE LUNG CANCER CELL LYSIS BY LYMPHOKINE- ACTIVATED KILLER CELLS VIA UPREGULATION OF ICAM-1. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0006295214004201
https://www.semanticscholar.org/paper/Cannabinoids-increase-lung-cancer-cell-lysis-by-via-Haustein-
Ramer/ae2a0a45c3a3e896a9986642c922fe6713526d08 Proapoptotic effect of endocannabinoids in prostate cancer cells. (Chile) (full – 2015) http://www.spandidos-publications.com/or/33/4/1599
Bi-directional CB1 receptor-mediated cardiovascular effects of cannabinoids in anaesthetized rats: role of the paraventricular nucleus (Poland/ Germany) (full–2015) http://jpp.krakow.pl/journal/archive/06_15/articles/03_article.html
Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor. (Australia/New Zealand) (full–2015) http://molpharm.aspetjournals.org/content/88/2/368.long
Synthetic and endogenous cannabinoids protect retinal neurons from AMPA excitotoxicity in vivo, via activation of CB1 receptors: Involvement of PI3K/Akt and MEK/ERK signaling pathways. (Greece) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0014483515001554
Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation. (Austria) (full – 2016) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156693
The cannabinoid receptor CB1 contributes to the development of ectopic lesions in a mouse model of endometriosis. (Italy/ Spain) (full – 2016) https://academic.oup.com/humrep/article/32/1/175/2448170
Effect of cannabinoids on CGRP release in the isolated rat lumbar spinal cord. (New Zealand) (abst – 2016) https://www.sciencedirect.com/science/article/abs/pii/S0304394015303517
https://www.semanticscholar.org/paper/Effect-of-cannabinoids-on-CGRP-release-in-the-rat-Milne-Ashton/b876db5b6435c90c723611edfeb7776b57d94042
Protective role of cannabinoid CB1 receptors and vascular effects of chronic administration of FAAH inhibitor URB597 in DOCA-salt hypertensive rats. (Poland) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0024320516301643
Comparing the effects of endogenous and synthetic cannabinoid receptor agonists on survival of gastric cancer cells. (Mexico) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0024320516305677
Cannabinoids prevent the amyloid β-induced activation of astroglial hemichannels: A neuroprotective mechanism. (Chile/ France) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27757991
Brain permeant and impermeant inhibitors of fatty-acid amide hydrolase suppress the development and maintenance of paclitaxel-induced neuropathic pain without producing tolerance or physical dependence in vivo and synergize with paclitaxel to reduce tumor cell line viability in vitro. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878658/
Ro 61-8048
Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835353/
RQ-00202730
Identification of a highly potent and selective CB2 agonist, RQ-00202730, for the treatment of irritable bowel syndrome (abst–2014) http://www.sciencedirect.com/science/article/pii/S0960894X14012578
RX-055
Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake (full–2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488949/
S-444823
Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent (full–2012) https://www.academia.edu/30122411/Discovery_of_S-444823_a_potent_CB1_CB2_dual_agonist_as_an_antipruritic_agent
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S-777469
Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent (abst–2012) http://www.sciencedirect.com/science/article/pii/S0960894X12002739
Non-clinical evaluation of the metabolism, pharmacokinetics and excretion of S-777469, a new cannabinoid receptor 2 selective agonist. (abst – 2014) https://www.tandfonline.com/doi/abs/10.3109/00498254.2013.805853?journalCode=ixen20
S-777469, a Novel Cannabinoid Type 2 Receptor Agonist, Suppresses Itch-Associated Scratching Behavior in Rodents through Inhibition of Itch Signal Transmission (Japan) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25721168
The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927043/
Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders (Spain/USA) (full–2016) http://journal.frontiersin.org/article/10.3389/fnins.2016.00406/full
The Inhibitory Effect of S-777469, a Cannabinoid Type 2 Receptor Agonist, on Skin Inflammation in Mice. (Japan) (abst – 2017) https://www.karger.com/Article/Abstract/455916
https://www.semanticscholar.org/paper/The-Inhibitory-Effect-of-S-777469%2C-a-Cannabinoid-2-Haruna-Soga/1caea50bcadc287a83cebafa8e99429bb1f8e776
Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease. (Italy) (full – 2019) https://www.sciencedirect.com/science/article/pii/S0223523418308572?via%3Dihub
SA-57
Delta-9 tetrahydrocannabinol (THC) and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation (ICSS) in mice. (link to PDF – 2014) http://jpet.aspetjournals.org/content/early/2014/11/14/jpet.114.218677.long
Simultaneous inhibition of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) shares discriminative stimulus effects with ∆9-THC in mice. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407717/
Effect of Pharmacological Modulation of the Endocannabinoid System on Opiate Withdrawal: A Review of the Preclinical Animal Literature. (Canada) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923145/
The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice. (USA/ Spain) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289715/
Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959103/
A novel inhibitor of endocannabinoid catabolic enzymes sheds light on behind the scene interplay between chronic pain, analgesic tolerance, and heroin dependence. (USA) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0028390816305226
Modulating the endocannabinoid pathway as treatment for peripheral neuropathic pain: a selected review of preclinical studies. (Canada) (full – 2017) http://apm.amegroups.com/article/view/16320/18208
Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771234/
SAB-378
Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone (SAB378), a peripherally restricted cannabinoid CB1/CB2 receptor agonist, inhibits gastrointestinal motility but has no effect on experimental colitis in mice (click “semanticscholar” for download–2010) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Naphthalen-1-yl-%284-pentyloxynaphthalen-1-
yl%29methanone+%28SAB378%29%2C+a+peripherally+restricted+cannabinoid+CB1%2FCB2+receptor+agonist%2C+inhibits+gastrointestinal+motility+but+has+no+effect+on+experimental+colitis+in+mice.+++++++++++&btnG=
Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists (link to PDF–2013) https://www.researchgate.net/publication/257754296_Control_of_spasticity_in_a_multiple_sclerosis_model_using_central_nervous_system-excluded_CB1_cannabinoid_receptor_agonists
Peripherally Restricted Cannabinoids for the Treatment of Pain. (USA) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26497478
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SAD-448
Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists. (link to PDF – 2013) https://www.researchgate.net/publication/257754296_Control_of_spasticity_in_a_multiple_sclerosis_model_using_central_nervous_system-excluded_CB1_cannabinoid_receptor_agonists
Peripherally Restricted Cannabinoids for the Treatment of Pain. (USA) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26497478
SAR-127303
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents (USA) (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284516/
SBFI26
Targeting Fatty Acid Binding Protein (FABP) Anandamide Transporters – A Novel Strategy for Development of Anti-Inflammatory and Anti-Nociceptive Drugs (full–2012) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0050968
Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26 (USA) (full–2016) http://journal.frontiersin.org/article/10.3389/fpsyt.2016.00054/full
SER-601 – a CB2 agonist
Cannabinoid 2 Receptor Agonist Improves Systemic Sensitivity to Insulin in High-Fat Diet/Streptozotocin-Induced Diabetic Mice (China) (full–2016) https://www.karger.com/Article/FullText/453171
SGT-24/cumyl-PINACA
Occupational transdermal poisoning with synthetic cannabinoid cumyl-PINACA (Slovenia) (abst–2016) https://www.semanticscholar.org/paper/Occupational-transdermal-poisoning-with-synthetic-Dobaja-Grenc/77f4256c4b78c268e26a5fe88c38c6aec78c4f8b
SLV-326
Cannabinoid antagonist SLV326 induces convulsive seizures and changes in the interictal EEG in rats (Netherlands/Russia/Germany) (full–2017) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165363
SMM–189
Visual deficits in mice after mild traumatic brain injury produced by primary overpressure blast are alleviated by the novel CB2 drug SMM189. (abst – 2014) http://iovs.arvojournals.org/article.aspx?articleid=2271359&resultClick=1
Motor, Visual and Emotional Deficits in Mice after Closed-Head Mild Traumatic Brain Injury Are Alleviated by the Novel CB2 Inverse Agonist SMM-189. (USA) (full – 2015) http://www.mdpi.com/1422-0067/16/1/758/htm
Preclinical evaluation of SMM-189, a cannabinoid receptor 2-specific inverse agonist. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506688/
Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders (Spain/USA) (full–2016) http://journal.frontiersin.org/article/10.3389/fnins.2016.00406/full
Mild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist (USA) (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052277
Abnormalities in Dynamic Brain Activity Caused by Mild Traumatic Brain Injury Are Partially Rescued by the Cannabinoid Type-2 Receptor Inverse Agonist SMM-189 (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562300/
Anti-inflammatory activity of cannabinoid receptor 2 ligands in primary hPDL fibroblasts (USA) (abst–2017) https://www.sciencedirect.com/science/article/pii/S0003996917303825
SMM-295 – a CB2 agonist
Selective Cannabinoid 2 Receptor Stimulation Reduces Tubular Epithelial Cell Damage after Renal Ischemia-Reperfusion Injury. (USA/ India) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774215/
“SPICE”/“SCRAs”
JWH018, a common constituent of ‘Spice’ herbal blends, is a potent and efficacious cannabinoid CB(1) receptor agonist (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931559/?tool=pubmed
Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds (link to PDF–2010) https://www.researchgate.net/publication/46382890_Monitoring_of_herbal_mixtures_potentially_containing_synthetic_cannabinoids_as_psychoactive_compounds
Panic Attack after Spice Abuse in a Patient with ADHD (link to 1st page– 2010) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0029-1243252
Pharmacological properties and dependence liabilities of synthetic cannabinoids (abst–2010) http://www.unboundmedicine.com/medline/ebm/record/20681249/abstract/%5BPharmacological_properties_and_dependence_liabilities_of_synthetic_cannabinoids%5D_
Chemical analysis of synthetic cannabinoids as designer drugs in herbal products. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20117892
Spice drugs as a new trend: mode of action, identification and legislation. (Greece) (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20566335
Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139381/?tool=pubmed
Beyond THC: The New Generation of Cannabinoid Designer Drugs. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187647/?tool=pubmed
CP47,497-C8 and JWH073, commonly found in ‘Spice’ herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094488/
Investigating a not-so-natural high. (full – 2011) http://pubs.acs.org/doi/full/10.1021/ac900564u
The secret “spice”: an undetectable toxic cause of seizure. (full – 2011) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726077/
Severe toxicity following synthetic cannabinoid ingestion. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165603/
Synthetic cannabinoid use: a case series of adolescents. (full – 2011) http://www.jahonline.org/article/S1054-139X%2811%2900277-1/fulltext
Convulsions Associated with the Use of a Synthetic Cannabinoid Product. (full – 2011) http://www.springerlink.com/content/9651q2672027n38g/fulltext.html
High-performance sport, marijuana, and cannabimimetics. (USA) (link to PDF – 2011) http://jat.oxfordjournals.org/content/35/9/624.long
Use of high-resolution accurate mass spectrometry to detect reported and previously unreported cannabinomimetics in “herbal high” products. (link to PDF – 2011) http://jat.oxfordjournals.org/content/34/5/252.long
Liquid chromatography-tandem mass spectrometry analysis of urine specimens for K2 (JWH-018) metabolites. (link to PDF – 2011) http://jat.oxfordjournals.org/content/35/7/487.long
The “new” marijuana. (link to PDF– 2011) https://www.researchgate.net/publication/49839766_The_New_Marijuana
“Legal highs” – new players in the old drama (link to PDF–2011) https://www.researchgate.net/publication/51450216_Legal_Highs_-_New_Players_in_the_Old_Drama
Synthetic cannabinoid use in New Zealand: a brief evaluation of inquiries to the New Zealand National Poisons Centre (letter–2011) http://www.nzma.org.nz/journal/read-the-journal/all-issues/2010-2019/2011/vol-124-no-1347/letter-schep
Psychosis Associated With Synthetic Cannabinoid Agonists: A Case Series (letter–2011) http://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.2011.11010176
Myocardial Infarction Associated With Use of the Synthetic Cannabinoid K2 (abst–2011) http://pediatrics.aappublications.org/content/128/6/e1622.long
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The impact of changes in UK classification of the synthetic cannabinoid receptor agonists in ‘Spice’. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21482092
Identification and characterization of JWH-122 used as new ingredient in “Spice-like” herbal incenses. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21482054
The emergence and analysis of synthetic cannabinoids. (abst – 2011) https://www.semanticscholar.org/paper/The-emergence-and-analysis-of-synthetic-Hudson-Ramsey/3ae7d6ac534b5595becaa729aa7e361e83dede81
“Spice” girls: synthetic cannabinoid intoxication. (abst – 2011) https://www.semanticscholar.org/paper/%22Spice%22-girls%3A-synthetic-cannabinoid-intoxication.-Schneir-Cullen/491692a598ecbb0b88b5944fc548c539be8675d8
Three cases of “spice” exposure (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21740143
Comparison of “herbal highs” composition. (abst – 2011) http://link.springer.com/article/10.1007%2Fs00216-011-4743-7
Cytotoxicity of synthetic cannabinoids found in “Spice” products: The role of cannabinoid receptors and the caspase cascade in the NG 108-15 cell line (abst–2011) http://www.sciencedirect.com/science/article/pii/S03784274
11015086 Effects of synthetic cannabinoids on electroencephalogram power spectra in rats (abst–2011) https://www.sciencedirect.com/science/article/pii/S0379073811002209?via%3Dihub
Detection of synthetic cannabinoids in herbal incense products. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21741374
Synthetic cannabinoids–the new “legal high” drugs. (Israel) (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22352277
Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21802885
Acute mental disturbance caused by synthetic cannabinoid: a potential emerging substance of abuse in Hong Kong. (full in English, abst in Chinese – 2012) http://www.easap.asia/index.php/component/k2/item/192-1202-v22n1-31-cr
Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288656/
AKI Associated with Synthetic Cannabinoids: A Case Series. (full – 2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613952/
Detection and disposition of JWH-018 and JWH-073 in mice after exposure to “Magic Gold” smoke. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677765/
Synthetic legal intoxicating drugs: The emerging ‘incense’ and ‘bath salt’ phenomenon. (full – 2012) https://www.mdedge.com/ccjm/article/89604/adolescent-medicine/synthetic-legal-intoxicating-drugs-emerging-incense-and-bath
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Acute Intoxication Caused by a Synthetic Cannabinoid in Two Adolescents (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470439/
Inhalation exposure to smoke from synthetic “marijuana” produces potent cannabimimetic effects in mice. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501554/
A survey study to characterize use of Spice products (synthetic cannabinoids) (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217086/
Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936256/
Determination of naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in mouse blood and tissue after inhalation exposure to ‘buzz’ smoke by HPLC/MS/MS (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697740/
Patterns of synthetic cannabinoid use in Australia. (full – 2012) http://onlinelibrary.wiley.com/doi/10.1111/j.1465-3362.2012.00519.x/full
Adolescent Exposure of JWH-018 “Spice” Produces Subtle Effects on Learning and Memory Performance in Adulthood. (full – 2012) http://file.scirp.org/Html/2-3900080_19505.htm
Synthetic cannabinoid and marijuana exposures reported to poison centers (full–2012) http://journals.sagepub.com/doi/full/10.1177/0960327111421945
Detection and quantification of new designer drugs in human blood: part 1 – synthetic cannabinoids (full–2012) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bks048
Prevalence of Synthetic Cannabinoids in U.S. Athletes: Initial Findings. (USA) (full – 2012) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bks066
Using dopamine research to generate rational cannabinoid drug policy. (USA) (full – 2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819603/
Analysis of 30 synthetic cannabinoids in serum by liquid chromatography-electrospray ionization tandem mass spectrometry after liquid-liquid extraction (link to PDF–2012) https://www.researchgate.net/publication/229082270_Analysis_of_30_synthetic_cannabinoids_in_serum_by_liquid_chromatography-electrospray_ionization_tandem_mass_spectrometry_after_liquid-liquid_extraction Acute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings. (link to PDF – 2012) https://www.researchgate.net/publication/230840840_Acute_toxicity_due_to_the_confirmed_consumption_of_synthetic_cannabinoid
s_Clinical_and_laboratory_findings Identification and structural characterization of the synthetic cannabinoid 3-(1- adamantoyl)-1-pentylindole as an additive in ‘herbal incense’ (link to PDF–2012) https://www.researchgate.net/publication/221855825_Identification_and_structural_characterization_of_the_synthetic_cannabinoid_3-1-adamantoyl-1-pentylindole_as_an_additive_in_’herbal_incense’
Spice: a new “legal” herbal mixture abused by young active duty military personnel (click “dticmil” for download–2012) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Spice%3A+a+new+%22legal%22+herbal+mixture+abused+by+young+active+duty+military+personnel.&btnG
Simultaneous analysis of several synthetic cannabinoids, THC, CBD and CBN, in hair by ultra-high performance liquid chromatography tandem mass spectrometry. Method validation and application to real samples. (click “unito” for download – 2012) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Simultaneous+analysis+of+several+synthetic+cannabinoids%2C+THC%2C+CBD+and+CBN%2C+in+hair+by+ultra-high+performance+liquid+chromatography+tandem+mass+spectrometry.+Method+validation+and+application+to+real+samples.+++ +++++++&btnG
Spice, bath salts, and the U.S. military: the emergence of synthetic cannabinoid receptor agonists and cathinones in the U.S. Armed Forces. (click “oup” for download–2012) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Spice%2C+bath+salts%2C+and+the+U.S.+military%3A+the+emergence+of+synthetic+cannabinoid+receptor+agonists+and+cathinones+in+the+U.S.+Armed+Forces.&btnG
Synthetic cannabis. (article – 2012) http://tidsskriftet.no/article/2896636/en_GB
The spice in France: mixed herbs containing synthetic cannabinoids. (abst in English–2012) http://www.ncbi.nlm.nih.gov/pubmed/22796613 (abst in French – 2012) https://www.jle.com/fr/revues/abc/e-docs/le_spice_en_france_melange_dherbes_contenant_des_cannabinoides_de_synthese_292843/article.phtml
Characterization of In Vitro Metabolites of CP 47,497, a Synthetic Cannabinoid, in Human Liver Microsomes by LC-MS/MS. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22931239
Headache after substance abuse: A diagnostic dilemma. (abst – 2012) https://www.sciencedirect.com/science/article/pii/S0967586811005017
Phenazepam and cannabinomimetics sold as herbal highs in New Zealand (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22924168
Synthetic cannabinoid use: recognition and management. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22418399
“Spice” and “k2” herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications of synthetic cannabinoid use in humans. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22691010
Risky Recreation: Synthetic Cannabinoids Have Dangerous Effects. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22801822
Internet Highs-Seizures After Consumption of Synthetic Cannabinoids Purchased Online. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22824736
Ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry screening method for direct analysis of designer drugs, “spice” and stimulants in oral fluid. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S0021967312012198
First European case of convulsions related to analytically confirmed use of the synthetic cannabinoid receptor agonist AM-2201. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22936123
Synthetic Cannabinoid Intoxication: A Case Series and Review. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22989695
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Synthetic Cannabinoid and Cathinone Use Among US Soldiers. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23007932
Adolescent Synthetic Cannabinoid Exposures Reported to Texas Poison Centers. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23023462
URB-754: A new class of designer drug and 12 synthetic cannabinoids detected in illegal products. (abst – 2012) https://www.sciencedirect.com/science/article/pii/S0379073812004343?via%3Dihub
DNA sequence analyses of blended herbal products including synthetic cannabinoids as designer drugs. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23092848
Identification, extraction and quantification of the synthetic cannabinoid JWH-018 from commercially available herbal marijuana alternatives. (abst – 2012) https://www.semanticscholar.org/paper/Identification%2C-extraction-and-quantification-of-Dunham-
Hooker/01fbee26cfcba0c01200b5006cc1d427889b4aa4 Determination of 22 synthetic cannabinoids in human hair by liquid chromatography- tandem mass spectrometry. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S1570023212004023
Synthetic cannabinoids in “spice-like” herbal blends: first appearance of JWH-307 and recurrence of JWH-018 on the German market. (abst – 2012) https://www.sciencedirect.com/science/article/pii/S0379073812002757?via%3Dihub
Analysis of synthetic cannabinoids in “spice-like” herbal highs: snapshot of the German market in summer 2011. ` (abst – 2012) http://link.springer.com/article/10.1007%2Fs00216-012-6122-4
Synthetic cannabis and respiratory depression. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23234589
“K2,” “Spice,” and “Bath Salts” – The In-Vogue Recreational Drugs – What the Intensivists Need to Know. (abst – 2012) https://www.safetylit.org/citations/index.php?fuseaction=citations.viewdetails&citationIds%5b%5d=citjournalarticle_400398_1
Synthetic Cannabinoids as Drugs of Abuse. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22530798
A Characterization of Synthetic Cannabinoid Exposures Reported to the National Poison Data System in 2010. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S0196064412002533
Spicing Up the Differential for Cyclic Vomiting: A Case of Synthetic-Cannabinoid Induced Hyperemesis Syndrome (CH) (link to download of abst – 2012) https://www.mayoclinicproceedings.org/article/S0025-6196(14)00566-7/fulltext
Emergency Physicians’ Knowledge of Cannabinoid Designer Drugs. (full – 2013) https://escholarship.org/uc/item/9mk2951f
Fascination and Social Togetherness-Discussions about Spice Smoking on a Swedish Internet Forum. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855086/
“Spiceophrenia”: a systematic overview of “Spice”-related psychopathological issues and a case report. (full – 2013) http://onlinelibrary.wiley.com/doi/10.1002/hup.2312/full
The K2/Spice Phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100246/
High Times, Low Sats: Diffuse Pulmonary Infiltrates Associated with Chronic Synthetic Cannabinoid Use. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657026/
Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685885/
Synthetic cannabinoids and potential reproductive consequences. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823745/
CB1 Receptor-Mediated Signaling Underlies the Hippocampal Synaptic, Learning and Memory Deficits Following Treatment with JWH-081, a New Component of Spice/K2 Preparations. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959795/
Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9- THC: Mechanism underlying greater toxicity? (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945037/
Ischemic stroke after use of the synthetic marijuana “spice”. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863350/
K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319529/
“Herbal incense”: Designer drug blends as cannabimimetics and their assessment by drug discrimination and other in vivo bioassays. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135441/
Moving around the molecule: Relationship between chemical structure and in vivo activity of synthetic cannabinoids. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944940/
Spice/K2 drugs – more than innocent substitutes for marijuana. (full – 2013) http://ijnp.oxfordjournals.org/content/17/3/509
Sulfaphenazole and α-Naphthoflavone Attenuate the Metabolism of the Synthetic Cannabinoids JWH-018 and AM2201 Found in K2/Spice. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154622/
Identification and Structural Elucidation of Four Cannabimimetic Compounds (RCS-4, AM-2201, JWH-203 and JWH-210) in Seized Products. (full – 2013) https://academic.oup.com/jat/article/37/2/56/857976
Detection of Synthetic Cannabinoids in Oral Fluid Using ELISA and LC-MS-MS. (full – 2013) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bkt067
Identification of Novel Third-Generation Synthetic Cannabinoids in Products by Ultra- Performance Liquid Chromatography and Time-of-Flight Mass Spectrometry. (full – 2013) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bkt062
Toxicological Findings of Synthetic Cannabinoids in Recreational Users. (full – 2013) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bkt068
Why should Cannabis be Considered Doping in Sports? (Brazil) (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654312/
‘Legal high’ associated Wallenberg syndrome. (UK) (full – 2013) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669865/
The Synthetic Cannabinoid Withdrawal Syndrome. (full – 2013) https://www.researchgate.net/publication/236266276_The_Synthetic_Cannabinoid_Withdrawal_Syndrome
Synthetic Cannabinoids: Crisis of The Decade. (full – 2013) https://www.researchgate.net/publication/281760203_Synthetic_cannabinoids_Crisis_of_the_decade
Kronic hysteria: Exploring the intersection between Australian synthetic cannabis legislation, the media, and drug-related harm. (Australia) (full – 2013) https://www.academia.edu/2451046/Kronic_hysteria_Exploring_the_intersection_between_Australian_synthetic_cannabis_legislation
_the_media_and_drug-related_harm LC/ESI-MS/MS method for quantification of 28 synthetic cannabinoids in neat oral fluid and its application to preliminary studies on their detection windows. (link to PDF – 2013) https://www.researchgate.net/publication/236087200_LCESI-
MSMS_method_for_quantification_of_28_synthetic_cannabinoids_in_neat_oral_fluid_and_its_application_to_preliminary_studies_o n_their_detection_windows Psychosis and Severe Rhabdomyolysis Associated with Synthetic Cannabinoid Use (link to PDF–2013) https://www.researchgate.net/publication/236070752_Psychosis_and_Severe_Rhabdomyolysis_Associated_with_Synthetic_Cannabinoid_Use_A_Case_Report Hospitalisation associated with use of the synthetic cannabinoid K2 (link to PDF–2013) https://www.researchgate.net/publication/247156865_Hospitalisation_associated_with_use_of_the_synthetic_cannabinoid_K2
Smart drugs: green shuttle or real drug? (link to PDF – 2013) https://www.researchgate.net/publication/248396950_Smart_drugs_Green_shuttle_or_real_drug
The pharmacologic and clinical effects of medical cannabis (Pdf–2013) https://www.theroc.us/researchlibrary/The%20Pharmacologic%20and%20Clinical%20Effects%20of%20Medical%20Cannabis.pdf
Manual for use by national drug analysis laboratories Recommended methods for the Identification and Analysis of Synthetic Cannabinoid Receptor Agonists in Seized Materials (link to download–2013) http://www.unodc.org/documents/scientific/STNAR48_Synthetic_Cannabinoids_ENG.pdf
Emergence and Properties of Spice and Bath Salts: A Medicinal Chemistry Perspective (click “academia” for download – 2013) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Emergence+and+properties+of+spice+and+bath+salts%3A+A+medicinal+chemistry+perspective&btnG
Notes from the Field: Severe Illness Associated with Synthetic Cannabinoid Use – Brunswick, Georgia, 2013 (report – 2013) http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6246a7.htm
Acute Kidney Injury Associated with Synthetic Cannabinoid Use — Multiple States, 2012. (report – 2013) http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6206a1.htm
Getting up to speed with the public health and regulatory challenges posed by new psychoactive substances in the information age. (editorial – 2013) http://onlinelibrary.wiley.com/doi/10.1111/add.12287/full
st Emerging drugs of abuse. (1 page – 2013) https://www.sciencedirect.com/science/article/pii/S0733862713000813?via%3Dihub
Prevalence of new designer drugs and their legal status in Japan. (abst in English, link to full in Japanese – 2013) https://www.jstage.jst.go.jp/article/yakushi/133/1/133_12-00247-6/_article/-char/ja/
Effect and occurrence of synthetic cannabinoids. (abst in English – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23736196
(full in Norwegian – 2013) http://tidsskriftet.no/2012/10/oversiktsartikkel/syntetiske-cannabinoider-effekt-og-forekomst
Suicidal ideation and self-harm following K2 use. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23304900
Synthetic cannabis: A comparison of patterns of use and effect profile with natural cannabis in a large global sample. (UK/ Australia) (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23291209
Synthetic Marijuana: Possibly A Lung’s Dying Breath. (abst – 2013) https://journal.chestnet.org/article/S0012-3692(16)43595-6/fulltext
Psychoactive substances-Some new, some old: A scan of the situation in the U.S. (abst – 2013) https://www.sciencedirect.com/science/article/pii/S0376871613003736
Review of detection frequency and type of synthetic cannabinoids in herbal compounds analyzed by Istanbul Narcotic Department of the Council of Forensic Medicine, Turkey. (abst – 2013) https://www.semanticscholar.org/paper/Review-of-detection-frequency-and-type-of-synthetic-Gurdal-
A%C5%9Firdizer/39730544cdb4b779bfca3506d9a2d0f4ed44e3e9 Synthetic Cannabinoid Overdose in a 20-Year-Old Male US Soldier. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23327506
Symptoms, toxicities, and analytical results for a patient after smoking herbs containing the novel synthetic cannabinoid MAM-2201. (abst – 2013) http://link.springer.com/article/10.1007/s11419-012-0166-1
Effects of acute detoxification of the herbal blend ‘Spice Gold’ on dopamine D2/3 receptor availability: A [18F]fallypride PET study. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23452563
Electroconvulsive Therapy (ECT) for Catatonia in a Patient With Schizophrenia and Synthetic Cannabinoid Abuse: A Case Report. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23670023
The omega and omega-1 monohydroxyl metabolites of the abused K2/Spice synthetic cannabinoids JWH-018 and JWH- 073 bind with high affinity and act as agonists at human cannabinoid 2 receptors (hCB2s). (abst – 2013) https://www.fasebj.org/doi/10.1096/fasebj.26.1_supplement.660.8
A Case of Cannabinoid Hyperemesis Syndrome Caused by Synthetic Cannabinoids. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23890687
Synthetic Cannabis and Acute Ischemic Stroke. (abst – 2013) https://www.semanticscholar.org/paper/Synthetic-Cannabis-and-Acute-Ischemic-Stroke-Bernson-Leung-Leung/89af18980e786e4f851a047710cdc718e4fa482a Synthetic Cannabinoids as a Cause for Black Carbonaceous Bronchoalveolar Lavage.(1) (abst – 2013) http://journal.chestnet.org/article/S0012-3692(16)42656-5/fulltext
Forensic investigation of K2, Spice, and “bath salt” commercial preparations: A three- year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24314548
Characteristics of the designer drug and synthetic cannabinoid receptor agonist AM-2201 regarding its chemistry and metabolism. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23832945
UR-144 in products sold via the Internet: Identification of related compounds and characterization of pyrolysis products. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23315949
Stability of 11 prevalent synthetic cannabinoids in authentic neat oral fluid samples: glass versus polypropylene containers at different temperatures. (Germany) (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23704054
Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S0041008X13004766
Diffuse Hemorrhagic Pulmonary Infiltrates: Unique Complication Of Synthetic Cannabinoid Abuse. (abst – 2013) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2013.187.1_MeetingAbstracts.A5043
Analysis of AM-2201 and metabolites in a drugs and driving case. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24574312
Deposition of JWH-018, JWH-073 and their metabolites in hair and effect of hair pigmentation. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24162819
Effects and risks associated with novel psychoactive substances: mislabeling and sale as bath salts, spice, and research chemicals. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965957/
A Gut Gone to Pot: A Case of Cannabinoid Hyperemesis Syndrome due to K2, a Synthetic Cannabinoid. (full – 2014) http://www.hindawi.com/journals/criem/2014/167098/
A Unique Case of Cardiac Arrest following K2 Abuse. (full – 2014) http://www.hindawi.com/journals/cric/2014/120607/
“SPICE II Plus” (link to download–2014) http://ift.de/fileadmin/user_upload/Literatur/Berichte/WS5_Systematic_Report_Overview_of_available_information_and_sources_final.pdf
Screening for synthetic cannabinoids in hair by using LC-QTOF MS: A new and powerful approach to study the penetration of these new psychoactive substances in the population (full–2014) http://www.academia.edu/16534370/Screening_for_synthetic_cannabinoids_in_hair_by_using_LC-QTOF_MS_A_new_and_powerful_approach_to_study_the_penetration_of_these_new_psychoactive_substances_in_the_population
A survey of synthetic cannabinoid consumption by current cannabis users (full–2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048873/
Δ9-THC exposure attenuates aversive effects and reveals appetitive effects of K2/’Spice’ constituent JWH-018 in mice. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157458/
Subarachnoid hemorrhage from a thoracic radicular artery pseudoaneurysm after methamphetamine and synthetic cannabinoid abuse: case report. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854594/
Synthetic cannabinoid use among patients in residential substance use disorder treatment: Prevalence, motives, and correlates. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161625/
Evaluation of a homogenous enzyme immunoassay for the detection of synthetic cannabinoids in urine. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127333/
Nephrotoxic Effects of Common and Emerging Drugs of Abuse. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220747/
Synthetic Cannabinoids: Use and predictors in a Community Sample of Young Adults. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362955/
Quantitative urine confirmatory testing for synthetic cannabinoids in randomly collected urine specimens. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363290/
K2-Not the Spice of Life; Synthetic Cannabinoids and ST Elevation Myocardial Infarction: A Case Report. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371021/
Pulmonary Effects of Synthetic Marijuana: Chest Radiography and CT Findings (full–2014) http://www.ajronline.org/doi/full/10.2214/AJR.14.13138
Synthetic cannabinoids: Epidemiology, pharmacodynamics, and clinical implications. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253059/
XLR-11 and UR-144 in Washington State and State of Alaska Driving Cases. (full – 2014) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bku067
New synthetic drugs in addictovigilance. (link to PDF – 2014) https://www.journal-therapie.org/articles/therapie/abs/2015/02/therapie150001/therapie150001.html
Urinary prevalence, metabolite detection rates, temporal patterns and evaluation of suitable LC-MS/MS targets to document synthetic cannabinoid intake in US military urine specimens. (link to PDF – 2014) https://www.researchgate.net/publication/266263177_Urinary_prevalence_metabolite_detection_rates_temporal_patterns_and_evaluation_of_suitable_LC-MSMS_targets_to_document_synthetic_cannabinoid_intake_in_US_military_urine_specimens
Use of Synthetic Cannabinoids in Patients With Psychotic Disorders: Case Series (link to PDF–2014) https://www.researchgate.net/publication/264657837_Use_of_Synthetic_Cannabinoids_in_Patients_With_Psychotic_Disorders_Case_Series
Synthetic marijuana “K2” induced ITP. (link to PDF – 2014) https://www.researchgate.net/publication/261767799_Synthetic_marijuana_K2_induced_ITP
Driving under the influence of synthetic cannabinoids (“Spice”): a case series. (link to PDF – 2014) https://www.researchgate.net/publication/236602999_Driving_under_the_influence_of_synthetic_cannabinoids_Spice_A_case_series
‘Crazy Monkey’ Poisons Man and Dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid. (link to PDF – 2014) https://www.researchgate.net/publication/262930652_’Crazy_Monkey’_Poisons_Man_and_Dog_Human_and_canine_seizures_due_to
_PB-22_a_novel_synthetic_cannabinoid Nephrotoxic effects of designer drugs: synthetic is not better! (link to PDF – 2014) https://www.researchgate.net/publication/261067458_Nephrotoxic_effects_of_designer_drugs_Synthetic_is_not_better
Identification and quantification of synthetic cannabinoids in ‘spice-like’ herbal mixtures: A snapshot of the German situation in the autumn of 2012 (download–2014) https://link.springer.com/article/10.1007%2Fs00216-012-6122-4
Emerging Drugs of Abuse: Clinical and Legal Considerations. (link to download – 2014) http://rimed.org/rimedicaljournal/2014/06/2014-06-41-psych-aoun.pdf
Acute kidney injury associated with smoking synthetic cannabinoid. (click “researchgate” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Acute+kidney+injury+associated+with+smoking+synthetic+cannabinoid.&btnG=
Smoking synthetic marijuana leads to self-mutilation requiring bilateral amputations. (click “wyanokecdn” for download – 2014) (warning – graphic photos) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Smoking+Synthetic+Marijuana+Leads+to+Self-
Mutilation+Requiring+Bilateral+Amputations&btnG Hair analysis as a tool to evaluate the prevalence of synthetic cannabinoids in different populations of drug consumers. (Italy) (click “academia” for download – 2014) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Hair+analysis+as+a+tool+to+evaluate+the+prevalence+of+synthetic+cannabinoids+in+different+populations+of+drug+consumers.&btnG
A ‘spicy’ encephalopathy: synthetic cannabinoids as cause of encephalopathy and seizure. (letter – 2014) http://ccforum.biomedcentral.com/articles/10.1186/s13054-014-0553-6
The rise in K2 use with varying clinical symptoms and the potential for ED crowding (letter – 2014) http://www.ajemjournal.com/article/S0735-6757%2814%2900930-9/abstract
Severe rhabdomyolysis and intracranial hemorrhage associated with synthetic cannabinoid: a case report. (abst in English – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25179201
(abst in Japanese – 2014) http://medicalfinder.jp/doi/abs/10.11477/mf.1436102331
Delayed seizure-like activity following analytically confirmed use of previously unreported synthetic cannabinoid analogues. (abst – 2014) https://www.ncbi.nlm.nih.gov/pubmed/25233895
Performance characteristics of an ELISA screening assay for urinary synthetic cannabinoids. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25167963
Investigation of the in vitro toxicological properties of the synthetic cannabimimetic drug CP-47,497-C8. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0041008X14001100
https://www.semanticscholar.org/paper/Investigation-of-the-in-vitro-toxicological-of-the-Koller-Auw%C3%A4rter/3834d3f14d23412d0f60a3ef3e9ef3430b578050
Spicing up the military: Use and effects of synthetic cannabis in substance abusing army personnel. (abst – 2014) https://www.semanticscholar.org/paper/Spicing-up-the-military%3A-Use-and-effects-of-in-army-Walker-
Neighbors/6ec1d6abbdc725988d825716a87c8d7e4a0cad93 Functional consequences of synthetic cannabinoid metabolites and CYP2C9 polymorphisms. (abst – 2014) https://www.fasebj.org/doi/10.1096/fasebj.28.1_supplement.838.4
A critical analysis of national policy relating to legal highs. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25159975
A case of acute cerebral ischemia following inhalation of a synthetic cannabinoid. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25241766
Simultaneous determination of five naphthoylindole-based synthetic cannabinoids and metabolites and their deposition in human and rat hair. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S0731708514004427
A case of law-evading herbs poisoning that induced shock and myocardial damage. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25771668
Acute Lung Injury Due To Synthetic Cannabis. (abst – 2014) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2014.189.1_MeetingAbstracts.A6122
Severe Lactic Acidosis In The Setting Of Synthetic Cannabinoid Use. (abst – 2014) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2014.189.1_MeetingAbstracts.A6483
A structure-reactivity relationship driven approach to the identification of a color test protocol for the presumptive indication of synthetic cannabimimetic drugs of abuse. (abst – 2014) https://www.sciencedirect.com/science/article/pii/S0379073814002631?via%3Dihub
Characterization of in vitro metabolites of JWH-018, JWH-073 and their 4-methyl derivatives, markers of the abuse of these synthetic cannabinoids. (abst – 2014) http://www.sciencedirect.com/science/article/pii/S1570023214001639
https://www.semanticscholar.org/paper/Characterization-of-in-vitro-metabolites-of-JWH-073-Gambaro-Arnoldi/54cc50ff6f6401cb05c220e8c9d7dc1c26862ea2
Harmful effects of law-evading herbs as a new trend in Japan: behavioral and cytotoxicological properties of synthetic cannabinoids. (abst – 2014) http://www.researchgate.net/publication/265649661_P-47harmful_effects_of_law-
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Intravenous Lipid Emulsion Therapy for Acute Synthetic Cannabinoid Intoxication: Clinical Experience in Four Cases. (full – 2015) http://www.hindawi.com/journals/criem/2015/180921/
Using Web searches to track interest in synthetic cannabinoids (aka ‘herbal incense’) (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412351/
Atypical diabetic ketoacidosis: case report. (Turkey) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342127/
Cardiovascular side effects related with use of synthetic cannabinoids “bonzai” : two case reports. (Turkey) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462325/
Synthetic cannabis-induced mania. (Turkey) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369931/
Legal highs: staying on top of the flood of novel psychoactive substances. (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521440/
Unintentional Pediatric Exposure to a Synthetic Cannabinoid (AB-PINACA) Resulting in Coma and Intubation. (USA) (full – 2015) http://www.annemergmed.com/article/S0196-0644%2815%2900426-6/fulltext
Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid. (Turkey) (full – 2015) http://www.wjgnet.com/1007-9327/full/v21/i37/10704.htm
Emerging drugs of abuse: current perspectives on synthetic cannabinoids. (France) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622447/
Rhabdomyolysis and Acute Kidney Injury Requiring Dialysis as a Result of Concomitant Use of Atypical Neuroleptics and Synthetic Cannabinoids. (USA) (full – 2015) http://www.hindawi.com/journals/crin/2015/235982/
Alcohol Versus Cannabinoids: A Review of Their Opposite Neuro-Immunomodulatory Effects and Future Therapeutic Potentials. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607066/
The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity. (USA) (full – 2015) http://www.hindawi.com/journals/cricc/2015/542490/
Synthetic cannabinoids: the multi-organ failure and metabolic derangements associated with getting high. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558292/
Synthetic cannabinoids and acute kidney injury. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569229/
A New Differential Diagnosis: Synthetic Cannabinoids-Associated Acute Renal Failure. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666428/
Synthetic cannabinoid use in a nationally representative sample of US high school seniors. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361370/
K2 and Spice use among a cohort of college students in southeast region of the USA. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526379/
Self-reported use of novel psychoactive substances in a US nationally representative survey: Prevalence, correlates, and a call for new survey methods to prevent underreporting. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633323/
Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497846/
Characteristics of novel psychoactive substance exposures reported to New York City Poison Center, 2011-2014. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767576/
Concentrations of AB-CHMINACA and AB-PINACA and Driving Behavior in Suspected Impaired Driving Cases. (USA) (full – 2015) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bkv091
Neurotoxicity of Synthetic Cannabinoids JWH-081 and JWH-210. (Republic of Korea) (full – 2015) http://www.biomolther.org/journal/view.html?volume=23&number=6&spage=597&year=2015
Δ-9-Tetrahydrocannabinol discriminative stimulus effects of AM2201 and related aminoalkylindole analogs in rats. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779682/
AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol-Like Effects in Mice. (USA) (full – 2015) http://jpet.aspetjournals.org/content/354/3/328.full
Novel psychoactive substance use by US adolescents: Characteristics associated with use of synthetic cannabinoids and synthetic cathinones. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927404/
Schedules of Controlled Substances: Extension of Temporary Placement of PB-22, 5F- PB-22, AB-FUBINACA and ADB-PINACA in Schedule I of the Controlled Substances Act. final order. (full – 2015) https://www.federalregister.gov/documents/2016/02/05/2016-02308/schedules-of-controlled-substances-extension-of-temporary-
placement-of-pb-22-5f-pb-22-ab-fubinaca The Internet and drug markets. (not given) (link to PDF – video – 2015) https://www.semanticscholar.org/paper/The-Internet-and-drug-markets.-Mounteney-Bo/2b26d4dab5171bd4c05b1818c3668c7990976423 Thalamic and Cerebellar Gray Matter Volume Reduction in Synthetic Cannabinoids Users. (Turkey) (link to PDF – 2015) https://www.researchgate.net/publication/277408945_Thalamic_and_Cerebellar_Gray_Matter_Volume_Reduction_in_Synthetic_Cannabinoids_Users
Differential physiological and behavioral cues observed in individuals smoking botanical marijuana versus synthetic cannabinoid drugs. (USA) (link to PDF – 2015) https://www.researchgate.net/publication/286636691_Differential_physiological_and_behavioral_cues_observed_in_individuals_smoking_botanical_marijuana_versus_synthetic_cannabinoid_drugs
Impact of a synthetic cannabinoid (CP-47,497-C8) on protein expression in human cells: evidence for induction of inflammation and DNA damage (Austria/Germany) (link to PDF–2015) https://www.researchgate.net/publication/280241782_Impact_of_a_synthetic_cannabinoid_CP-47497-C8_on_protein_expression_in_human_cells_evidence_for_induction_of_inflammation_and_DNA_damage
Cannabinoids and Cytochrome P450 Interactions. (Czech Republic) (link to PDF–2015) https://www.researchgate.net/publication/286964899_Cannabinoids_and_Cytochrome_P450_Interactions
Synthetic Cannabinoids. (USA) (link to PDF – 2015) https://www.researchgate.net/publication/276112846_Synthetic_Cannabinoids
Metabolism of classical cannabinoids and the synthetic cannabinoid JWH-018. (link to PDF – 2015) https://www.researchgate.net/publication/273782255_Metabolism_of_Classical_Cannabinoids_and_the_Synthetic_Cannabinoid_JWH-018
The adverse health effects of synthetic cannabinoids with emphasis on psychosis-like effects. (Netherlands) (link to PDF – 2015) https://www.researchgate.net/publication/270966118_The_adverse_health_effects_of_synthetic_cannabinoids_with_emphasis_on_psychosis-like_effects
Deaths linked to synthetic cannabinoids. (Australia) (link to PDF – 2015) https://www.researchgate.net/publication/273639870_Deaths_linked_to_synthetic_cannabinoids
Synthetic cannabinoids pharmacokinetics and detection methods in biological matrices (USA) (download–2015) https://www.researchgate.net/publication/274708387_Synthetic_cannabinoids_pharmacokinetics_and_detection_methods_in_biological_matrices
Synthetic cannabinoids as a cause for black carbonaceous bronchoalveolar lavage. (2) (USA) (link to download – 2015) http://casereports.bmj.com/content/2015/bcr-2015-211391.full.pdf
Risk of emergency medical treatment following consumption of cannabis or synthetic cannabinoids in a large global sample. (UK) (click “psuedu” for download – 2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Risk+of+emergency+medical+treatment+following+consumption+of+cannabis+or+synthetic+cannabinoids+in+a+large+global+sample.&btnG
A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment. (click “curtinedu” for download – 2015) https://scholar.google.com/scholar?q=A+systematic+review+of+adverse+events+arising+from+the+use+of+synthetic+cannabinoids+and+their+associated+treatment&hl=en&as_sdt=0&as_vis=1&oi=scholart The effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135. (click “academia” for download – 2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=The+effects+of+bioisosteric+fluorine+in+synthetic+cannabinoid+designer+drugs+JWH-018%2C+AM-2201%2C+UR-144%2C+XLR-11%2C+PB-22%2C+5F-PB-22%2C+APICA%2C+and+STS- 135.+++++++&btnG
Notes from the Field: Increase in Reported Adverse Health Effects Related to Synthetic Cannabinoid Use – United States, January-May 2015. (report – 2015) http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6422a5.htm
Notes from the Field: Severe Illness Associated with Reported Use of Synthetic Cannabinoids — Mississippi, April 2015. (report – 2015) http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6439a7.htm
st “Spice” Can Really Heat Things Up. (USA) (1 page – 2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4600
Synthetic cannabinoids: spread, addiction biology & current perspective of personal health hazard. (Germany) (abst in German & English – 2015) https://www.thieme-connect.com/DOI/DOI?10.1055/s-0034-1399307
Stimulation of in vivo dopamine transmission and intravenous self-administration in rats and mice by JWH-018, a Spice cannabinoid. (Italy/ France/ USA) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0028390815300861
Novel case of synthetic cannabinoid hyperemesis resulting in rhabdomyolysis and acute renal failure. (USA) (abst – 2015) http://www.ajemjournal.com/article/S0735-6757%2815%2900743-3/abstract
Hyperthermia and severe rhabdomyolysis from synthetic cannabinoids. (USA) (abst – 2015) http://www.ajemjournal.com/article/S0735-6757(15)00490-8/abstract
Synthetic cannabinoid withdrawal: A new demand on detoxification services. (New Zealand) (abst – 2015) https://onlinelibrary.wiley.com/doi/abs/10.1111/dar.12225
A Synthetic Cannabinoid MAM-2201 Potently Suppresses Synaptic Transmission via Activation of Presynaptic CB1 Receptors and Reduces Synaptically-Evoked Intracellular Ca2+ Transients in Cerebellar Purkinje Cells. (Japan) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0028390815000817
A Common Source Outbreak of Severe Delirium Associated with Exposure to the Novel Synthetic Cannabinoid ADB-PINACA. (USA) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25726258
Genotoxic properties of representatives of alkylindazoles and aminoalkyl-indoles which are consumed as synthetic cannabinoids. (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0278691515000836
Withdrawal Seizures Seen In the Setting of Synthetic Cannabinoid Abuse. (USA) (abst – 2015) http://www.ajemjournal.com/article/S0735-6757%2815%2900169-2/abstract
Case reports of synthetic cannabinoid XLR-11 associated fatalities. (USA) (abst – 2015) https://www.sciencedirect.com/science/article/pii/S037907381500167X
JWH-018 impairs sensorimotor functions in mice. (Italy) (abst – 2015) https://www.sciencedirect.com/science/article/abs/pii/S0306452215004534
https://www.semanticscholar.org/paper/JWH-018-impairs-sensorimotor-functions-in-mice-Ossato-Vigolo/e56c80a5e45266db76e9d1a9e3f18ff7942e572e
“Legal Highs” – An Emerging Epidemic of Novel Psychoactive Substances. (Poland) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26070762
Quantitation of Synthetic Cannabinoids in Plant Materials Using High Performance Liquid Chromatography with UV Detection (Validated Method). (abst – 2015) https://www.semanticscholar.org/paper/Quantitation-of-Synthetic-Cannabinoids-in-Plant-UV-Ciolino/d91848f39121edc48ef61846612f5e8f49234f96
Myocardial Ischemia Secondary to Synthetic Cannabinoid (K2) Use in Pediatric Patients. (USA) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26165442
Psyclones: a roller coaster of life? Hidden synthetic cannabinoids and stimulants in apparently harmless products. (abst – 2015) https://www.semanticscholar.org/paper/Psyclones%3A-a-roller-coaster-of-life-Hidden-and-in-Santacroce-Corazza/6fdb82b6a8c505260068954f88696579d52066bd
A New Threat: Synthetic Marijuana Associated Lung Disease. (USA) (abst – 2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4684
Teenage Cardiac Arrest Following Abuse of Synthetic Cannabis. (New Zealand) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26256565
Synthetic Cannabinoid Abuse in Adolescents: A Case Series. (Turkey) (abst – 2015) https://www.sciencedirect.com/science/article/abs/pii/S0736467915006757
Pharmacological properties of law-evading chemical substances. (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26394508
Kiken drugs: current status of abuse among youth in the nightlife areas of Tokyo. (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26394509
Tetrahydrocannabinol pharmacokinetics; new synthetic cannabinoids; road safety and cannabis. (France) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26427296
Suspected synthetic cannabinoid toxicosis in a dog. (USA) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26473510
The behavioral profile of spice and synthetic cannabinoids in humans. (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26548494
Native CB1 receptor affinity, intrisic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135. (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0028390815301817
Are the last grade medical students aware of the danger of synthetic cannabinoids? (Turkey) (abst – 2015) http://www.jflmjournal.org/article/S1752-928X(15)00220-6/fulltext
Pharmacology and toxicology of the synthetic cannabinoid receptor agonists (abst–2015) http://link.springer.com/article/10.1007/s13546-015-1104-4
Delayed seizure-like activity following analytically confirmed use of previously unreported synthetic cannabinoid analogues. (abst – 2015) http://journals.sagepub.com/doi/full/10.1177/0960327114550886
K2 types and their contents: are product disclosures true? (abst – 2015) http://www.ajemjournal.com/article/S0735-6757(15)00181-3/fulltext
Update: Drug-Related Emergency Department Visits Involving Synthetic Cannabinoids. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/books/NBK350768/
Acute myocardial infarction, associated with the use of a synthetic adamantyl- cannabinoid: a case report. (UK) (full – 2016) http://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-016-0045-1
Genotoxic properties of XLR-11, a widely consumed synthetic cannabinoid, and of the benzoyl indole RCS-4. (Austria/ Germany) (full – 2016) http://link.springer.com/article/10.1007/s00204-016-1664-4/fulltext.html
Rising Threat; Bonsai. (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910010/
Chest pain, troponin rise, and ST-elevation in an adolescent boy following the use of the synthetic cannabis product K2. (New Zealand) (full – 2016) http://www.annalspc.com/article.asp?issn=0974-2069;year=2016;volume=9;issue=1;spage=79;epage=81;aulast=Zaleta
Case Series of Synthetic Cannabinoid Intoxication from One Toxicology Center. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899060/
A Curious Case of Inhalation Fever Caused by Synthetic Cannabinoid. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917070/
Adverse Effects of Synthetic Cannabinoids: Management of Acute Toxicity and Withdrawal. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923337/
Synthetic Cannabinoid ‘Bonzai’ Intoxication: Six Case Series. (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894237/
Unusual side effect of cannabis use: acute abdomen due to duodenal perforation. (Turkey) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936980/
The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927043/
Synthetic Cannabinoid Induced acute Tubulointerstitial Nephritis and Uveitis Syndrome: A Case Report and Review of Literature. (Turkey) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948465/
First-Episode of Synthetic Cannabinoid-Induced Psychosis in a Young Adult, Successfully Managed with Hospitalization and Risperidone. (USA) (full – 2016) http://www.hindawi.com/journals/crips/2016/7257489/
Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice. (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929166/
Acute Poisonings from Synthetic Cannabinoids – 50 U.S. Toxicology Investigators Consortium Registry Sites, 2010-2015. (full – 2016) http://www.cdc.gov/mmwr/volumes/65/wr/mm6527a2.htm
Highlights of the 2011 Drug Abuse Warning Network (DAWN) Findings on Drug- Related Emergency Department Visits. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/books/NBK384680/
Increase in Adverse Reactions Associated with Use of Synthetic Cannabinoids – Anchorage, Alaska, 2015-2016. (full – 2016) http://www.cdc.gov/mmwr/volumes/65/wr/mm6540a4.htm
“When ‘Bad’ is ‘Good'”: Identifying Personal Communication and Sentiment in Drug- Related Tweets. (USA) (full – 2016) http://publichealth.jmir.org/2016/2/e162/
Synthetic Cannabis Overdose and Withdrawal in a Young Adult: A Case Report, Commentary on Regulation, and Review of the Literature. (USA) (full – 2016) https://www.hindawi.com/journals/crips/2016/3640549/
Effectiveness of the synthetic cannabinoids seminar. (Turkey) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121273/
Adding Spice to the Porridge: The development of a synthetic cannabinoid market in an English prison. (full – 2016) https://www.sciencedirect.com/science/article/pii/S0955395916303073
“Zombie” Outbreak Caused by the Synthetic Cannabinoid AMB-FUBINACA in New York. (USA) (full – 2016) http://www.nejm.org/doi/full/10.1056/NEJMoa1610300#t=articleDiscussion
Acute Eosinophilic Pneumonia with Respiratory Failure Induced by Synthetic Cannabinoid Inhalation. (Turkey) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156457/
Traditional marijuana, high-potency cannabis and synthetic cannabinoids: increasing risk for psychosis. (UK) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032490/
Acute Rhabdomyolysis Following Synthetic Cannabinoid Ingestion. (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960936/
Clinical characteristics of synthetic cannabinoid-induced psychosis in relation to schizophrenia: a single-center cross-sectional analysis of concurrently hospitalized patients. (Turkey) (full – 2016) https://www.dovepress.com/clinical-characteristics-of-synthetic-cannabinoid-induced-psychosis-in-peer-reviewed-fulltext-article-NDT Synthetic Cannabis Overdose and Withdrawal in a Young Adult: A Case Report, Commentary on Regulation, and Review of the Literature. (USA) (full – 2016) https://www.hindawi.com/journals/crips/2016/3640549/
Associations of Posttraumatic Stress Disorder Symptoms With Marijuana and Synthetic Cannabis Use Among Young Adult U.S. Veterans: A Pilot Investigation. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869907/
Synthetic Cannabinoid Use and Descriptive Norms among Collegiate Student-Athletes. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945387/
Correlates of new psychoactive substance use among a self-selected sample of nightclub attendees in the United States. (USA/ Australia/ UK) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072356/
Simultaneous Analysis of Cannabinoid and Synthetic Cannabinoids in Dietary Supplements Using UPLC with UV and UPLC-MS-MS. (full – 2016) https://academic.oup.com/jat/article-lookup/doi/10.1093/jat/bkw027
A preliminary evaluation of synthetic cannabinoid use among adolescent cannabis users: Characteristics and treatment outcomes. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993666/
Self-reported use of novel psychoactive substances among attendees of electronic dance music venues. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093056/
Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation. (UK) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135680/
Clinical Effects of Synthetic Cannabinoid Receptor Agonists Compared with Marijuana in Emergency Department Patients with Acute Drug Overdose. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135672/
Examination of YouTube videos related to synthetic cannabinoids. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315684/
Pharmacological characterization of repeated administration of the first generation abused synthetic cannabinoid CP47,497. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644386/
Evaluation of first generation synthetic cannabinoids on binding at non-cannabinoid receptors and in a battery of in vivo assays in mice. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028280/
Age, period, and cohort effects in synthetic cannabinoid use among US adolescents, 2011-2015. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996475/
Synthetic cannabinoid drug use as a cause or contributory cause of death. (USA) (full–2016) https://www.academia.edu/25518565/Synthetic_cannabinoid_drug_use_as_a_cause_or_contributory_cause_of_death
Legal regulated markets have the potential to reduce population levels of harm associated with cannabis use. (UK) (full – 2016) https://onlinelibrary.wiley.com/doi/full/10.1111/add.13390
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH- 018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence. (Italy) (link to PDF – 2016) https://www.researchgate.net/publication/304454922_Synthetic_cannabinoid_JWH-018_and_its_halogenated_derivatives_JWH-018-Cl_and_JWH-018-Br_impair_Novel_Object_Recognition_in_mice_Behavioral_electrophysiological_and_neurochemical_evidence
Novel Psychoactive Substances: the pharmacology of stimulants and hallucinogens. (UK) (link to PDF – 2016) https://www.researchgate.net/publication/298788436_Novel_Psychoactive_Substances_the_pharmacology_of_stimulants_and_halluci
nogens They Were Getting High on What? Evaluating Novel Psychoactive Drug Knowledge Among Practitioners. (USA) (link to PDF – 2016) https://www.researchgate.net/publication/289502576_They_Were_Getting_High_on_What_Evaluating_Novel_Psychoactive_Drug_Knowledge_Among_Practitioners Buying drugs on a Darknet market: A better deal? Studying the online illicit drug market through the analysis of digital, physical and chemical data. (Switzerland) (link to PDF – 2016) https://www.researchgate.net/publication/307970354_Buying_drugs_on_a_Darknet_market_A_better_deal_Studying_the_online_illicit_drug_market_through_the_analysis_of_digital_physical_and_chemical_data
Signs and symptoms associated with synthetic cannabinoid toxicity: systematic review. (New Zealand) (link to PDF – 2016) https://www.researchgate.net/publication/306526731_Signs_and_symptoms_associated_with_synthetic_cannabinoid_toxicity_Systematic_review
Wastewater analysis and drugs — a European multi-city study. (not given) (link to PDF–2016) http://www.emcdda.europa.eu/topics/pods/waste-water-analysis
Synthetic Cannabinoids and Their Effects on the Cardiovascular System (USA) (link to PDF–2016) https://www.researchgate.net/publication/283422020_Synthetic_Cannabinoids_and_Their_Effects_on_the_Cardiovascular_System
Anti-N-methyl-D-aspartate receptor encephalitis and drug abuse – the probable role of molecular mimicry or the overstimulation of CB receptors in a 17-year-old adolescent – case report. (Hungary) (download – 2016) https://pdfs.semanticscholar.org/c544/ce38fb260ef703056b4f22c477c9f2fcb06f.pdf
Abnormal white matter integrity in synthetic cannabinoid users. (Turkey/ Australia) (download – 2016) https://www.researchgate.net/publication/308050798_Abnormal_white_matter_integrity_in_synthetic_cannabinoid_users
Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids. (USA) (abst–2016) https://pubmed.ncbi.nlm.nih.gov/27278640/
Psychiatric comorbidity associated with synthetic cannabinoid use compared to cannabis. (USA) (click “researchgate” for download – 2016) https://scholar.google.com/scholar?q=Psychiatric+comorbidity+associated+with+synthetic+cannabinoid+use+compared+to+cannabis&hl=en&as_sdt=0&as_vis=1&oi=scholart
From “herbal highs” to the “heroin of cannabis”: Exploring the evolving discourse on synthetic cannabinoid use in a Norwegian Internet drug forum. (Norway) (click “researchgate” for download – 2016) https://scholar.google.com/scholar?cluster=11310281650500497654&hl=en&as_sdt=0,5
New psychoactive substances: driving greater complexity into the drug problem. (click “wiley” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=New+psychoactive+substances%3A+driving+greater+complexity+into+the+drug+problem.&btnG
Can your heart handle the spice: A case of acute myocardial infarction and left ventricular apical thrombus. (USA) (click “researchgate” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Can+your+heart+handle+the+spice%3A+A+case+of+acute+myocardial+infarction+and+left+ventricular+apical+thrombus.+++++++++++++++&btnG
From niche to stigma-Headshops to prison: Exploring the rise and fall of synthetic cannabinoid use among young adults. (UK) (click “canterbury” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22From+niche+to+stigma-Headshops+to+prison%3A+Exploring+the+rise+and+fall+of+synthetic+cannabinoid+use+among+young+adults.%22&btnG
Pre-hospital identification and post-recovery challenges of intoxication with synthetic cannabinoid containing legal high products such as ‘Exodus Damnation’. (UK/ Portugal) (click “stiracuk” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Pre-hospital+identification+and+post-recovery+challenges+of+intoxication+with+synthetic+cannabinoid+containing+legal+high+products+such+as+%27Exodus+Damnati on%27.%22&btnG
A multicenter retrospective survey of poisoning after consumption of products containing novel psychoactive substances from 2013 to 2014 in Japan. (Japan) (click “view PDF” for download – 2016) https://www.semanticscholar.org/paper/A-multicenter-retrospective-survey-of-poisoning-of-Kamijo-Takai/584215dab8809b523e6b1eef3eb462580993067d
Effect of synthetic cannabinoids on spontaneous neuronal activity: Evaluation using Ca2+ spiking and multi-electrode arrays. (Canada) (click “open access” then “ncrpublicationscanadaca” for download – 2016) https://www.semanticscholar.org/paper/Effect-of-synthetic-cannabinoids-on-spontaneous-and-Tauskela-Comas/2932e8404f4116dc42820c86d36646a37b1ccdc0 Interpersonal violence and synthetic cannabinoids. (UK) (letter – 2016) http://www.bjoms.com/article/S0266-4356(16)30219-4/abstract
Synthetic cannabinoids: undesirable alternatives to natural marijuana (1st page–2016) http://www.tandfonline.com/doi/abs/10.3109/00952990.2016.1139584?journalCode=iada20
Synthetic Cannabinoid Exposure A New Risk for Children? (USA) (1st page–2016) http://journals.sagepub.com/doi/full/10.1177/0009922816664065
Drug Dependence and Cytotoxicity of Law-evading Drugs: Their Identities Explored from Basic Research. (abst in English – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26725670 (link to PDF in Japanese – 2016) https://www.jstage.jst.go.jp/article/yakushi/136/1/136_15-00228-1/_article/-char/ja/
Prevalence of new psychoactive substances in Northeast Asia from 2007 to 2015. (abst in English & Arabic – 2016) https://freepaper.me/downloads/abstract/10.1016/j.forsciint.2016.10.010
Synthetic cannabinoids: A new addiction matrix. (France) (abst in English & French – 2016) https://www.sciencedirect.com/science/article/pii/S0755498216303876
Drug Dependence and Toxicity of Law-Evading Drugs: Their Mechanisms Explored from Basic Research. (Japan) (abst in English – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27703102
(abst in Japanese – 2016) http://medicalfinder.jp/doi/abs/10.11477/mf.1416200568
Acute Psychosis after Consumption of Synthetic Cannabinoids (Austria) (abst in German & English–2016) https://www.thieme-connect.com/DOI/DOI?10.1055/s-0042-103425
Comparison of outcome expectancies for synthetic cannabinoids and botanical marijuana. (USA) (abst – 2016) http://www.tandfonline.com/doi/full/10.3109/00952990.2015.1135158
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. (Italy) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S0278584616300069
Catatonia secondary to synthetic cannabinoid use in two patients with no previous psychosis. (USA) (abst – 2016) http://onlinelibrary.wiley.com/doi/10.1111/ajad.12318/full
Synthetic Cannabinoid Receptor Agonist-Associated Psychotic Disorder: A Case Report. (abst – 2016) (Turkey) https://www.ncbi.nlm.nih.gov/pubmed/27370060
Characteristics of Synthetic Cannabinoid and Cannabis Users Admitted to a Psychiatric Hospital: A Comparative Study. (Israel) (abst – 2016) https://europepmc.org/article/med/27379411
Synthetic cannabinoids revealing adrenoleukodystrophy . (Israel) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0967586815004567
https://www.semanticscholar.org/paper/Synthetic-cannabinoids-revealing-Fellner-
Benninger/8f0f9681b328e42bf3b659a21865198f9b938cb9 Simultaneous detection of 93 synthetic cannabinoids by liquid chromatography-tandem mass spectrometry and retrospective application to real forensic samples. (Germany) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27400642
Identification and quantification of synthetic cannabinoids in “spice-like” herbal mixtures: update of the German situation for the spring of 2015. (abst – 2016) http://link.springer.com/article/10.1007/s11419-015-0292-7
https://www.semanticscholar.org/paper/Identification-and-quantification-of-synthetic-in-a-Langer-Lindigkeit/8b010e2a3b08be81ff2159bf139e9e29f72889b1
Adverse effects after the use of JWH-210 – a case series from the EU Spice II plus project. (Germany) (abst – 2016) https://www.semanticscholar.org/paper/Adverse-effects-after-the-use-of-JWH-210-a-case-the-Hermanns-Clausen-Kithinji/7f72a2b975a3b9ff5c94c83c951d24cd69574361
Screening new psychoactive substances in urban wastewater using high resolution mass spectrometry. (Italy/ Spain/ USA) (abst – 2016) https://link.springer.com/article/10.1007%2Fs00216-016-9521-0
https://www.semanticscholar.org/paper/Screening-new-psychoactive-substances-in-urban-high-Gonz%C3%A1lez-Mari%C3%B1o-Gracia-Lor/55ad313050c2be42d138cd03685f15deaaa553e9
The Changing Drug Culture: Emerging Drugs of Abuse and Legal Highs. (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26881769
Suicide attempt with a mix of synthetic cannabinoids and synthetic cathinones: Case report of non-fatal intoxication with AB-CHMINACA, AB-FUBINACA, alpha-PHP, alpha-PVP and 4-CMC. (Slovenia) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S0379073816000372
https://www.semanticscholar.org/paper/Suicide-attempt-with-a-mix-of-synthetic-and-Case-of-Klav%C5%BE-Gorenjak/5d617f3037f464668b9a0edc3dcc2d9ed13f4a1e Dangerous drugs: products containing synthetic chemicals. (Japan) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26915246
Metabolites of synthetic cannabinoids in hair-proof of consumption or false friends for interpretation? (Germany) (abst – 2016) http://link.springer.com/article/10.1007%2Fs00216-016-9422-2
https://www.semanticscholar.org/paper/Metabolites-of-synthetic-cannabinoids-in-hair%E2%80%94proof-Franz-Angerer/66f3eddc9dffe7edc51cd7e3d8ff824838415e4e Do police arrestees substitute legal highs for other drugs? (abst – 2016) https://www.semanticscholar.org/paper/Do-police-arrestees-substitute-legal-highs-for-Wilkins-Parker/e9ce624219e60ec7c2085d263a45c55d65264512
Sickle Cell Crisis Complicated by Synthetic Cannabinoid Abuse: A Case Report. (USA) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26956672
Synthetic Cannabinoids-Further Evidence Supporting the Relationship Between Cannabinoids and Psychosis. (Italy) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/26970364
Dermatological Aspects of Synthetic Cannabinoid Addiction. (Turkey) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27028361
Toxicological impact of JWH-018 and its phase I metabolite N-(3-hydroxypentyl) on human cell lines. (Portugal/ USA) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S0379073816301104
Epidemiology and clinical features of toxicity following recreational use of synthetic cannabinoid receptor agonists: a report from the United Kingdom national poisons information service. (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27091041
International Trends in Spice Use: Prevalence, Motivation for Use, Relationship to Other Substances, and Perception of Use and Safety for Synthetic Cannabinoids. (abst – 2016) https://www.sciencedirect.com/science/article/abs/pii/S0361923016300880?via%3Dihub
LACTIC ACIDOSIS: A RARE MANIFESTATION OF SYNTHETIC MARIJUANA INTOXICATION. (USA) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27159480
Variation in commercial smoking mixtures containing third-generation synthetic cannabinoids. (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27161591
Prevalence and Correlates of Any and Frequent Synthetic Cannabinoid Use in a Representative Sample of High School Students. (USA) (abst – 20 16) http://www.ncbi.nlm.nih.gov/pubmed/27191966
Acute intoxication of four individuals following use of the synthetic cannabinoid MAB- CHMINACA. (Poland) (abst – 2016) https://www.semanticscholar.org/paper/Acute-intoxication-of-four-individuals-following-of-Adamowicz-Giero%C5%84/0f007aff43e55616ca2e88d7502ce9882c45a202
Influence of law changes affecting synthetic cannabinoid availability and frequency of hospital presentations: 4-year national survey. (New Zealand) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27349159
Quantification of synthetic cannabinoids in herbal smoking blends using NMR. (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27400773
Repeated Thrombosis After Synthetic Cannabinoid Use. (USA) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27595371
The Synthetic Cannabinoids Phenomenon. (France) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27655416
New psychoactive substances: an overview on recent publications on their toxicodynamics and toxicokinetics. (abst – 2016) http://link.springer.com/article/10.1007%2Fs00204-016-1812-x
Acute Effects of Synthetic Cannabinoids: Update 2015. (France) (abst – 2016) https://www.semanticscholar.org/paper/Acute-effects-of-synthetic-cannabinoids%3A-Update-Tournebize-Gibaja/a2a9b8b350237715f8b58475580b4ffa05ea1adc
“Just one bad high:” considering synthetic cannabinoid outcome expectancies in adolescents. (USA) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27749024
MDMB-CHMICA: Availability, Patterns of Use, and Toxicity Associated With This Novel Psychoactive Substance. (UK) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27759479
Characteristics associated with synthetic cannabinoid use among patients treated in a public psychiatric emergency setting. (USA) (abst – 2016) https://www.semanticscholar.org/paper/Characteristics-associated-with-synthetic-use-among-Joseph-Manseau/31bb1523704c1892afe1e7d16fff428dfc08c9ea
Focus on cannabinoids and synthetic cannabinoids. (France) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27861784
Freeze-and-thaw stability and long-term-stability of 84 synthetic cannabinoids in serum. (Germany) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/2786308
Identification and quantification of synthetic cannabinoids in “spice-like” herbal mixtures: Update of the German situation for the spring of 2016. (abst – 2016) https://www.semanticscholar.org/paper/Identification-and-quantification-of-synthetic-in-Langer-Lindigkeit/8bbe63eeecfbea8ce4c81e66aecb71b34f6237f4
Buzz Juice: Neurological sequelae of synthetic cannabinoids. (USA) (abst – 2016) https://www.sciencedirect.com/science/article/abs/pii/S0967586816307731
Paradoxical increase in synthetic cannabinoid emergency-related presentations after a citywide ban: Lessons from Houston, Texas. (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27936903
Occupational transdermal poisoning with synthetic cannabinoid cumyl-PINACA. (Slovenia) (abst – 2016) https://www.semanticscholar.org/paper/Occupational-transdermal-poisoning-with-synthetic-Dobaja-Grenc/77f4256c4b78c268e26a5fe88c38c6aec78c4f8b
Dried haematic microsamples and LC-MS/MS for the analysis of natural and synthetic cannabinoids. (Italy/ USA/ Austria) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S1570023216306171
New challenges in toxicology of new psychoactive substances exemplified by fatal cases after UR-144 and UR-144 with pentedrone administration determined by LC-ESI-MS- MS in blood. (Poland) (full in Polish & English – 2017) https://www.termedia.pl/Journal/-82/Artykul-31005
Stroke and cannabis use in patients with no cardiovascular risk factors: a systematic review of case reports. (Colombia) (full in English, link to full in Spanish – 2017) https://www.elsevier.es/en-revista-neurologia-english-edition–495-avance-resumen-stroke-cannabis-use-in-patients-S2173580819301063
Assessing the experience of using synthetic cannabinoids by means of interpretative phenomenological analysis. (Hungary/ USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303230/
AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5′-Diphospho- Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes (Republic of Korea) (full – 2017) http://www.mdpi.com/1420-3049/22/3/443/htm
Clinical Interpretation of Urine Drug Tests. (USA) (full – 2017) http://www.mayoclinicproceedings.org/article/S0025-6196(16)30825-4/fulltext
Thrombotic microangiopathy associated with synthetic cannabinoid receptor agonists. (USA) (full – 2017) http://sci.amegroups.com/article/view/15022/15166
Bilateral renal cortical necrosis associated with smoking synthetic cannabinoids. (USA) (full – 2017) https://www.wjgnet.com/2307-8960/full/v5/i6/234.htm
Novel Psychoactive Substances-Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs. (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563308/
Motor vehicle collisions caused by the ‘super-strength’ synthetic cannabinoids, MAM- 2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014. (Japan) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486620/
Health Risk Behaviors With Synthetic Cannabinoids Versus Marijuana. (USA) (full – 2017) http://pediatrics.aappublications.org/content/139/4/e20162675.long
Longitudinal Predictors of Synthetic Cannabinoid Use in Adolescents. (USA) (full – 2017) http://pediatrics.aappublications.org/content/139/4/e20163009.long
Psychostimulant Effect of the Synthetic Cannabinoid JWH-018 and AKB48: Behavioral, Neurochemical, and Dopamine Transporter Scan Imaging Studies in Mice . (Italy/ USA) (full – 2017) https
://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543288/ Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health. (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572353/
Spice-y Kidney Failure: A Case Report and Systematic Review of Acute Kidney Injury Attributable to the Use of Synthetic Cannabis. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424589/
Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398321/
Synthetic Cannabinoid and Mitragynine Exposure of Law Enforcement Agents During the Raid of an Illegal Laboratory — Nevada, 2014 . (USA) (full – 2017) https://www.cdc.gov/mmwr/volumes/66/wr/mm6647a3.htm
A spicy status: Synthetic cannabinoid (spice) use and new-onset refractory status epilepticus—A case report and review of the literature. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721953/
Myocardial Ischemia with Cannabinoid Use in an Adolescent. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790209/
Fatal Mesenteric Ischemia Induced by Synthetic Cannabinoids: A Case Report and Literature Review. (Israel) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748310/
Oral fluid vs. Urine Analysis to Monitor Synthetic Cannabinoids and Classic Drugs Recent Exposure. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931376/
Characteristics and Treatment of Patients with Clinical Illness Due to Synthetic Cannabinoid Inhalation Reported by Medical Toxicologists: A ToxIC Database Study. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440319/
Synthetic cannabinoid “Black Mamba” infidelity in patients presenting for emergency stabilization in Colorado: a P SCAN Cohort. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786486/
Running Out of Options: Rhabdomyolysis Associated with Cannabis Hyperemesis. Syndrome. (USA) (full – 2017) https://link.springer.com/article/10.1007%2Fs11606-017-4111-1
Increased in synthetic cannabinoids-related harms: Results from a longitudinal web-based content analysis. (USA/ Australia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545681/
Synthetic cannabinoid induced acute respiratory depression: Case series and literature review. (USA) (full – 2017) https://www.sciencedirect.com/science/article/pii/S2213007116302064
Synthetic cannabinoids found in “spice” products alter body temperature and cardiovascular parameters in conscious male rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599362/
Antidote to cannabinoid intoxication: the CB1 receptor inverse agonist, AM251, reverses hypothermic effects of the CB1 receptor agonist, CB-13, in mice (UK) (full–2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647190/
Neurocognition and subjective experience following acute doses of the synthetic cannabinoid JWH-018: A phase 1, placebo-controlled, pilot study. (Netherlands/ Germany) (full – 2017) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14066
Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392241/
Could serum S100B be a predictor of neuronal damage and clinical poor outcomes associated with the use of synthetic cannabinoids? S100B to predict neuronal damage of SC in the ED. (Turkey) (full – 2017) https://www.sciencedirect.com/science/article/pii/S0735675717307027
Synthetic Pot: Not Your Grandfather’s Marijuana. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329767/
Analytical differentiation of quinolinyl- and isoquinolinyl-substituted 1-(5-fluoropentyl)- 1H-indole-3-carboxylates: 5F-PB-22 and its ten isomers. (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215287/
The risk of violence associated with novel psychoactive substance misuse in patients presenting to acute mental health services. (UK) (full – 2017) https://onlinelibrary.wiley.com/doi/full/10.1002/hup.2606
Qualitative Analysis and Detection of the Pyrolytic Products of JWH-018 and 11 Additional Synthetic Cannabinoids in the Presence of Common Herbal Smoking Substrates. (full – 2017) https://academic.oup.com/jat/article/41/6/551/3872301
Impact of synthetic cannabinoids on the duration of opioid-related withdrawal and craving among patients of addiction clinics in Kazakhstan: A prospective case-control study. (Kazakhstan/ Italy/ UK) (full – 2017) https://onlinelibrary.wiley.com/doi/full/10.1002/hup.2618
Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790819/
Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of five novel synthetic cannabinoids in rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823726/
Lethal high: acute disseminated encephalomyelitis (ADEM) triggered by toxic effect of synthetic cannabinoid black mamba. (UK) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534782/
A Cloud on the Horizon – A survey into the use of electronic vaping devices for recreational drug and new psychoactive substance (NPS) administration. (UK) (full – 2017) https://academic.oup.com/qjmed/article/111/1/9/4158164
Alterations of the hematologic cells in synthetic cannabinoid users. (Turkey) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817267/
Delirium and High Creatine Kinase and Myoglobin Levels Related to Synthetic Cannabinoid Withdrawal. (Turkey) (full – 2017) https://www.hindawi.com/journals/crim/2017/3894749/
Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. (USA/ Australia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363769/
Ischemic stroke associated with the use of a synthetic cannabinoid (spice). (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863350/
Apparent CB1 receptor rimonabant affinity estimates: combination with THC and synthetic cannabinoids in the mouse in vivo triad model. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478909/
A market on both “sides” of the law: The use of the hidden web for the sale of new psychoactive substances. (UK) (full – 2017) https://onlinelibrary.wiley.com/doi/full/10.1002/hup.2596
Detection of the recently emerged synthetic cannabinoid 5 F-MDMB-PICA in ‘legal high’ products and human urine samples. (Germany/ Australia/ USA) (click “Open access” then “Wiley for full – 2017) https://www.semanticscholar.org/paper/Detection-of-the-recently-emerged-synthetic-in-and-Mogler-Franz/ff 17870ae1ba52df6b1f9583f0e2b18909f4b597
Atrial fibrillation following synthetic cannabinoid abuse. (Turkey) (link to PDF– 2017) http://archivestsc.com/jvi.aspx?un=TKDA-70367
Hepatotoxicity associated to synthetic cannabinoids use. (Italy) (link to PDF – 2017) https://www.europeanreview.org/article/12426
Immunoassay screening in urine for synthetic cannabinoids – an evaluation of the diagnostic efficiency. (Germany) (link to PDF – 2017) https://www.researchgate.net/publication/313036453_Immunoassay_screening_in_urine_for_synthetic_cannabinoids_- _An_evaluation_of_the_diagnostic_efficiency Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly. (USA/ Germany) (link to PDF – 2017) https://www.researchgate.net/publication/319703443_Cardiovascular_effects_of_marijuana_and_synthetic_cannabinoids_The_good_the_bad_and_the_ugly
The effects of synthetic cannabinoids on executive function. (Israel/ Hungary) (link to PDF – 2017) https://www.researchgate.net/publication/313320166_The_effects_of_synthetic_cannabinoids_on_executive_function
Assessment of types of synthetic cannabinoids in narcotic cases assessed by the Council of Forensic Medicine between 2011-2015, Ankara, Turkey (link to PDF – 2017) https://www.researchgate.net/publication/320319596_Assessment_of_types_of_synthetic_cannabinoids_in_narcotic_cases_assessed_by_the_Council_of_Forensic_Medicine_between_2011-2015_Ankara_Turkey
Severe neurological symptoms following synthetic cannabinoid intoxication. (Netherlands) (link to PDF – 2017) https://www.researchgate.net/publication/317213313_Severe_neurological_symptoms_following_synthetic_cannabinoid_intoxication
Bilateral multiple exudative retinal detachments and macular edema in a patient diagnosed with synthetic cannabinoid (Bonzai) intoxication (Turkey) (link to PDF–2017) https://www.researchgate.net/publication/322026415_Bilateral_multiple_exudative_retinal_detachments_and_macular_edema_in_a_patient_diagnosed_with_synthetic_cannabinoid_Bonzai_intoxication
Acute and residual effects in adolescent rats resulting from exposure to the novel synthetic cannabinoids AB-PINACA and AB-FUBINACA (Australia) (link to PDF–2017) https://www.researchgate.net/publication/312491240_Acute_and_residual_effects_in_adolescent_rats_resulting_from_exposure_to_the_novel_synthetic_cannabinoids_AB-PINACA_and_AB-FUBINACA
Synthetic Cannabinoids: psychopharmacology, clinical aspects, and psychotic onset. (Italy/UK) (link to PDF–2017) https://www.semanticscholar.org/paper/Synthetic-Cannabinoids%3A-Psychopharmacology%2C-Onset.-Martinotti-
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The impact of the Psychoactive Substances Act 2016 on the online availability of MDMB-CHMICA. (download – 2017) https://tinyurl.com/y93f8bzx
Synthetic Cannabis Analogues and Suicidal Behavior: Case Report. (Portugal) (download – 2017) Synthetic Cannabis Analogues and Suicidal Behavior: Case Report Synthetic cannabinoids in the kidneys. (Turkey) (link to download – 2017) Synthetic cannabinoids in the kidneys Psychometric Properties of the Turkish Versions of the Cannabis Use Problems Identification Test (CUPIT) and the Adult Cannabis Problems Questionnaire (CPQ). (Turkey) (click “halileksi” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Psychometric+Properties+of+the+Turkish+Versions+of+the+Cannabis+Use+Problems+Identi%EF%AC%81cation+Test+%28CUPIT%29+and+the+Adult+Cannabis+Problems+Questionnaire+%28CP Q%29.%22&btnG
Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study. (Germany) (click “researchgate” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Synthetic+Cannabinoid+Use+in+a+Psychiatric+Patient+Population%3A+A+Pilot+Study&btnG
The Role of Public Health in Combatting Synthetic Cannabinoid Use in Adolescents. (USA) (click “getmyanswers” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22The+Role+of+Public+Health+in+Combatting+Synthetic+Cannabinoid+Use+in+Adolescents.%22&btnG
Teens and Spice: A Review of Adolescent Fatalities Associated with Synthetic Cannabinoid Use. (USA/ Canada/ UK) (Click “researchgate” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Teens+and+Spice%3A+A+Review+of+Adolescent+Fatalities+Associated+with+Synthetic+Cannabinoid+Use.+%22&btnG
Human Toxicity Caused by Indole and Indazole Carboxylate Synthetic Cannabinoid Receptor Agonists: From Horizon Scanning to Notification. (UK) (click “aaccjnls” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Human+Toxicity+Caused+by+Indole+and+Indazole+Carboxylate+Synthetic+Cannabinoid+Receptor+Agonists%3A+From+Horizon+Scanning+to+Notification%22&btnG
Intoxication from the novel synthetic cannabinoids AB-PINACA and ADB-PINACA: A case series and review of the literature. (USA) (click “ucsfedu” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Intoxication+from+the+novel+synthetic+cannabinoids+AB-PINACA+and+ADB-PINACA%3A+A+case+series+and+review+of+the+literature%22&btnG
Metabolic Profile of Synthetic Cannabinoids 5F-PB-22, PB-22, XLR-11 and UR-144 by Cunninghamella elegans. (Australia) (click “utseduau” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Metabolic+Profile+of+Synthetic+Cannabinoids+5F-PB-22%2C+PB-22%2C+XLR-11+and+UR-144+by+%09Cunninghamella+elegans.&btnG New-Onset Refractory Status Epilepticus Associated With the Use of Synthetic st Cannabinoids. (USA) (1 page – 2017) http://www.psychosomaticsjournal.com/article/S0033-3182(16)30124-4/fulltext
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New Psychoactive Substances (NPS) – a Challenge for the Addiction Treatment Services. st (link to 1 page – 2017) https://www.thieme-connect.com/DOI/DOI?10.1055/s-0043-102059
Issues with monitoring the safety of psychoactive products under a legal regulated market for new psychoactive substances (‘legal highs’) in New Zealand. (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28229493
Three fatalities associated with the synthetic cannabinoids 5F-ADB, 5F-PB-22, and AB- CHMINACA. (Germany) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S037907381730453X
Clinical Characteristics of Synthetic Cannabinoid Use in a Large Urban Psychiatric Emergency Setting. (USA) (abst – 2017) http://www.tandfonline.com/doi/abs/10.1080/10826084.2016.1263663?journalCode=isum20
Acute side effects after consumption of the new synthetic cannabinoids AB- CHMINACA and MDMB-CHMICA. (Germany) (abst – 2017) https://www.semanticscholar.org/paper/Acute-side-effects-after-consumption-of-the-new-and-Hermanns-Clausen-M%C3%BCller/776b327b167b5e3dcf51fbd44196c630b0bd7347
Strokes are possible complications of cannabinoids use. (France) (abst – 2017) https://www.epilepsybehavior.com/article/S1525-5050(16)30735-1/fulltext
Profound hypotension and bradycardia in the setting of synthetic cannabinoid intoxication – A case series. (USA) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28238395
The effects of synthetic cannabinoid UR-144 on the human body-A review of 39 cases. (Poland) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0379073817300853?via%3Dihub
The impact of Australian legislative changes on synthetic cannabinoid exposures reported to the New South Wales Poisons Information Centre. (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28343112
Suspected Synthetic Cannabinomimetic Intoxication. (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28357892
Determination of AB-CHMINACA and its metabolites in human hair and their deposition in hair of abusers. (Republic of Korea) (abst – 2017) https://www.semanticscholar.org/paper/Determination-of-AB-CHMINACA-and-its-metabolites-in-Sim-Cho/1fbf6a08c92f08a706eb5e3f6d02410d09857f7f Supraventricular tachycardia and acute confusion following ingestion of e-cigarette fluid containing AB-FUBINACA and ADB-FUBINACA: a case report with quantitative analysis of serum drug concentrations. (China) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28393558
Analytical confirmation of synthetic cannabinoids in a cohort of 179 presentations with acute recreational drug toxicity to an Emergency Department in London, UK in the first half of 2015. (UK/ Belgium) (abst – 2017) https://www.semanticscholar.org/paper/Analytical-confirmation-of-synthetic-cannabinoids-a-Abouchedid-Hudson/43414db17daf86cd4644238f6de9e27ea06f3ffe JWH-122 Consumption Adverse Effects: A Case of Hallucinogen Persisting Perception Disorder Five-Year Follow-Up. (Italy) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28441106
Clinical and financial implications of emergency department visits for synthetic marijuana. (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28457767
Synthetic cannabinoid use in an acute psychiatric inpatient unit. (Australia) (abst– 2017) https://www.ncbi.nlm.nih.gov/pubmed/28503792
The illegal synthetic cannabinoid drug market in Israel – evolution and new challenges. (Israel) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28530077
Fatal Intoxication by 5F-ADB and Diphenidine: Detection, Quantification, and Investigation of their Main Metabolic Pathways in Human by LC/MS/MS and LC/Q- TOFMS. (Japan) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28544560
Identification and quantification of synthetic cannabinoids in ‘spice-like’ herbal mixtures: Update of the German situation in early 2017. (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0379073817301901
A new challenge in forensic toxicology exemplified by a case of murder under the influence of a synthetic cannabinoid – AM-2201. (Poland) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S1344622316302292
Synthetic cannabinoids: the hidden side of Spice drugs. (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28692429
AB-CHMINACA-induced sudden death from non-cardiogenic pulmonary edema. (Japan) (abst – 2017) https://www.semanticscholar.org/paper/AB-CHMINACA-induced-sudden-death-from-pulmonary-Maeda-Kikura-Hanajiri/e73fbbbb944c987d9d6e5d27416783c9e87fcffa
Chapter Four – Spicing Up Pharmacology: A Review of Synthetic Cannabinoids From Structure to Adverse Events. (abst – 2017) http://www.sciencedirect.com/science/article/pii/S105435891730042X
A synthetic cannabinoid JWH-210 reduces lymphoid organ weights and T-cell activator levels in mice via CB2 receptors. (Republic of Korea) (abst – 2017) https://link.springer.com/article/10.1007/s00210-017-1418-8
https://www.semanticscholar.org/paper/A-synthetic-cannabinoid-JWH-210-reduces-lymphoid-in-Gu-
Lee/2dadde42d082cf11e42188369e41402dbdd9a8aa The analysis of 132 novel psychoactive substances in human hair using a single step extraction by tandem LC/MS. (Australia/ Greece) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0379073817303407?via%3Dihub
Electrocardiographic alterations in patients consuming synthetic cannabinoids. (Turkey) (abst – 2017) https://journals.sagepub.com/doi/abs/10.1177/0269881117736918?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=jopa https://www.semanticscholar.org/paper/Electrocardiographic-alterations-in-patients-Ozturk-Erdogan/162de1859f1630dec51bf8933b337dda272c715e
Reports of adverse health effects related to synthetic cannabinoid use in New York State. (USA) (abst – 2017) https://www.semanticscholar.org/paper/Reports-of-adverse-health-effects-related-to-use-in-Papadopoulos-Cummings/95e12a5043473d3efefc353f0605a4018e4155d6
The “Spice” Trade A Profit Estimation of EU Online Vendors of Herbal Smoking Mixtures (abst–2017) http://journals.sagepub.com/doi/abs/10.1177/1057567717745345
Synthetic Cannabinoid Abuse and a Rare Alpha-1-Antitrypsin Mutant Causing Acute Fulminant Hepatitis: A Case Report and Review of the Literature. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733121/
Street drug use among emergency patients in a Public Hospital in Turkey (full–2018) http://www.njcponline.com/article.asp?issn=1119-3077;year=2018;volume=21;issue=1;spage=99;epage=106;aulast=Caliskan
Repeated Exposure to the “Spice” Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats. (USA) (full – 2018) https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00055/full
Notes from the Field: Acute Poisonings from a Synthetic Cannabinoid Sold as Cannabidiol — Utah, 2017–2018. (USA) (full – 2018) https://www.cdc.gov/mmwr/volumes/67/wr/mm6720a5.htm?s_cid=mm6720a5_w
Notes from the Field: Outbreak of Severe Illness Linked to the Vitamin K Antagonist Brodifacoum and Use of Synthetic Cannabinoids — Illinois, March–April 2018. (USA) (full – 2018) https://www.cdc.gov/mmwr/volumes/67/wr/mm6721a4.htm?s_cid=mm6721a4_w
The influence of tightening regulations on patients with new psychoactive substance‐ related disorders in Japan. (full – 2018) https://onlinelibrary.wiley.com/doi/full/10.1002/npr2.12035
Multilevel population-based cross-sectional study examining school substance-misuse policy and the use of cannabis, mephedrone and novel psychoactive substances among students aged 11-16 years in schools in Wales. (UK) (full – 2018) http://bmjopen.bmj.com/content/8/6/e020737.long
A new side effect of synthetic cannabinoid use by the bucket (waterpipe) method: Acute respiratory distress syndrome (ARDS). (Turkey) (full – 2018) https://www.sciencedirect.com/science/article/pii/S2452247317300171
Intracerebral Hemorrhage with Multiple Intracranial Arterial Stenoses in a Synthetic Cannabinoid “Spice” User. (Turkey) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898148/
Acute myocardial infarction triggered by use of synthetic cannabis. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914480/
Psychiatric symptoms and synthetic cannabinoid use: Information for clinicians. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007529/
The Endocannabinoid System, Aggression, and the Violence of Synthetic Cannabinoid Use, Borderline Personality Disorder, Antisocial Personality Disorder, and Other Psychiatric Disorders. (full – 2018) https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00041/full
Synthetic and Non-synthetic Cannabinoid Drugs and Their Adverse Effects-A Review From Public Health Prospective. (Israel) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999798/
Sales and Advertising Channels of New Psychoactive Substances (NPS): Internet, Social Networks, and Smartphone Apps. (USA) (full – 2018) http://www.mdpi.com/2076-3425/8/7/123/htm
Simple screening procedure for 72 synthetic cannabinoids in whole blood by liquid chromatography-tandem mass spectrometry. (Poland) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002442/
Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues. (UK/ Italy/ Greece) (full – 2018) http://www.mdpi.com/2076-3425/8/7/133/htm
Acute carotid thrombosis and ischemic stroke following overdose of the synthetic cannabinoid K2 in a previously healthy young adult male. (USA) (full – 2018) https://www.sciencedirect.com/science/article/pii/S193004331830027X?via%3Dihub
Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC. (USA) (full – 2018) https://www.frontiersin.org/articles/10.3389/fphar.2018.01084/full
The Modulating Role of Sex and Anabolic-Androgenic Steroid Hormones in Cannabinoid Sensitivity. (Italy) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212868/
Clinical and analytical experience of the National Poison Control Centre with synthetic cannabinoids. (Serbia) (full – 2018) https://content.sciendo.com/view/journals/aiht/69/2/article-p178.xml
The Effects of Cannabinoids on Executive Functions: Evidence from Cannabis and Synthetic Cannabinoids-A Systematic Review. (Israel) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870358/
Cannabinoids: from pot to lab. (Spain) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158663/
Cannabis use among middle and high school students in Ontario: a school-based cross- sectional study. (Canada) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878957/
A case of synthetic cannabinoid poisoning in Croatia. (full – 2018) https://content.sciendo.com/view/journals/aiht/69/2/article-p186.xml
Therapeutic Use of Synthetic Cannabinoids: Still an Open Issue? (full – 2018) https://www.clinicaltherapeutics.com/article/S0149-2918(18)30332-1/fulltext
Synthetic Cannabinoid Exposure in Adolescents Presenting for Emergency Care. (Canada/ USA) (full – 2018) https://www.tandfonline.com/doi/full/10.1080/15563650.2019.1687900
An Outbreak of Synthetic Cannabinoid-Associated Coagulopathy in Illinois. (USA) (full – 2018) https://www.nejm.org/doi/full/10.1056/NEJMoa1807652
Pharmacodynamic effects, pharmacokinetics, and metabolism of the synthetic cannabinoid AM-2201 in male rats. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246978/
Activity-Based Detection of Cannabinoids in Serum and Plasma Samples. (Belgium/ Germany) (full – 2018) https://academic.oup.com/clinchem/article/64/6/918/5608707
Coma, Seizures, Atrioventricular Block, and Hypoglycemia in an ADB-FUBINACA Body-Packer. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289710/
Pro-psychotic effects of synthetic cannabinoids: interactions with central dopamine, serotonin, and glutamate systems. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419500/
Rates of Synthetic Cannabinoid Use in Adolescents Admitted to a Treatment Facility. (USA) (abst & link to full with registration – 2018) https://www.ncbi.nlm.nih.gov/pubmed/30216711
The Spice of Life…and Death: A Case Presentation and Review of Synthetic Marijuana Use in Mississippi. (USA) (full – pages 16-17 – 2018) https://issuu.com/jmsmamanagingeditor/docs/september_2016_jmsma_final_1.13.17
Evolution of clinical characteristics and outcomes of synthetic cannabinoid receptor agonist exposure in the U.S.: analysis of National Poison Data System data from 2010 to 2015. (link to PDF – 2018) https://www.researchgate.net/publication/325407086_Evolution_of_clinical_characteristics_and_outcomes_of_synthetic_cannabinoid_receptor_agonist_exposure_in_the_US_analysis_of_National_Poison_Data_System_data_from_2010_to_2015
A new cause of ischaemic priapism: Synthetic cannabinoids (Turkey) (link to PDF–2018) https://www.researchgate.net/publication/324159803_A_new_cause_of_ischaemic_priapism_Synthetic_cannabinoids
The effects of synthetic cannabinoids (SCs) on brain structure and function. (Israel) (link to PDF – 2018) https://www.researchgate.net/publication/326821008_The_effects_of_synthetic_cannabinoids_SCs_on_brain_structure_and_function
Pulmonary embolism due to synthetic cannabinoid use: Case report. (Turkey) (link to PDF, full in English, abst in Turkish – 2018) http://archivestsc.com/jvi.aspx?un=TKDA-84425
Speckle-tracking strain assessment of left ventricular dysfunction in synthetic cannabinoid and heroin users. (Turkey) (click “Full Text PDF” for download – 2018) http://www.anatoljcardiol.com/jvi.aspx?un=AJC-76429
Evaluation of cognitive functions in individuals with synthetic cannabinoid use disorder and comparison to individuals with cannabis use disorder. (Turkey) (click “researchgate” for download – 2018) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Evaluation+of+cognitive+functions+in+individuals+with+synthetic+cannabinoid+use+disorder+%09and+comparison+to+individuals+with+cannabis+use+disorder.&btnG
Spicing it up – synthetic cannabinoid receptor agonists and psychosis – a systematic review. (UK) (click “kclacuk” for download – 2018) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Spicing+it+up+-
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Toxicology of Marijuana, Synthetic Cannabinoids, and Cannabidiol in Dogs and Cats. (USA) (click “mybestbudca” for download – 2018) https://scholar.google.com/scholar?q=%22Toxicology+of+Marijuana,+Synthetic+Cannabinoids,+and+Cannabidiol+in+Dogs+and+Cats%22&hl=en&as_sdt=0&as_vis=1&oi=scholart
Metabolism of Synthetic Cannabinoid Receptor Agonists Encountered in Clinical Casework: Major in vivo Phase I Metabolites of JWH-007, JWH-019, JWH-203, JWH- 307, UR-144, XLR-11, AM-2201, MAM-2201 and AM-694 in Human Urine Using LC- MS/MS. (Germany/ UK) (click “View PDF” for download – 2018) https://www.semanticscholar.org/paper/Metabolism-of-synthetic-cannabinoid-receptor-in-in-Hutter-Br%C3%B6cker/a5361519e2ebccf8bbe493e6bc39d23790e8e722 New and Emerging Illicit Psychoactive Substances. (1st page – 2018) https://www.medical.theclinics.com/article/S0025-7125(18)30014-2/abstract
Psychoactive substances use in Réunion Island and Mayotte, French departments in Indian Ocean. (France) (abst in English & French – 2018) https://www.em-consulte.com/en/module/displayarticle/article/1214544/impression/vue6
Impact of synthetic cannabinoid use on hospital stay in patients with bipolar disorder versus schizophrenia, or other psychotic disorders. (USA) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0165178117311101
Old and new synthetic cannabinoids: lessons from animal models. (Italy) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29376443
Differential approaches to the treatment of acute psychosis due to the use of synthetic cannabinoids. (Russia) (abst – 2018) https://link.springer.com/article/10.1007%2Fs11055-019-00724-0
https://www.semanticscholar.org/paper/A-Differential-Approach-to-the-Treatment-of-Acute-Kekelidze-Klimenko/1fdae2e9c8599f08b6d809bacd823a5095dedecc
The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis. (Portugal) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0378427418300377
Functional effects of synthetic cannabinoids versus Δ9 -THC in mice on body temperature, nociceptive threshold, anxiety, cognition, locomotor/exploratory parameters and depression. (Israel) (abst – 2018) https://www.semanticscholar.org/paper/Functional-effects-of-synthetic-cannabinoids-versus-Schreiber-Bader/bdcc732eca01fb98bf65981d65180ad3c9839dd5
How much can synthetic cannabinoid damage the heart? A case of cardiogenic shock following resistant ventricular fibrillation after synthetic cannabinoid use. (Turkey) (abst – 2018) https://www.semanticscholar.org/paper/How-much-can-synthetic-cannabinoid-damage-the-heart-Yamano%C4%9Flu-Yamano%C4%9Flu/70fea34b662451a46276829c002baf4e171e2e4a
ANNALS EXPRESS: Analytical evidence to show letters impregnated with novel psychoactive substances (NPS) are a means of getting drugs to inmates within the UK prison service. (UK) (abst – 2018) http://journals.sagepub.com/doi/abs/10.1177/0004563218767462
Unintentional Exposure of an Infant to Synthetic Cannabinoid (Bonzai) Related to the Parent’s Use. (Turkey) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29698342
The role of cannabinoid signaling in acute and chronic kidney diseases. (Italy) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29706358
Implementation of a generic SFC-MS method for the quality control of potentially counterfeited medicinal cannabis with synthetic cannabinoids. (Belgium) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S1570023218302034?via%3Dihub
The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonists as New Psychoactive Substances: Origins. (Australia/ USA) (abst – 2018) https://link.springer.com/chapter/10.1007/164_2018_143
Severe illness associated with reported use of synthetic cannabinoids: a public health investigation (Mississippi, 2015). (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29989463
Brodifacoum-contaminated synthetic marijuana: clinical and radiologic manifestations of a public health outbreak causing life-threatening coagulopathy. (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/30022308
Synthetic cannabinoids are substrates and inhibitors of multiple drug-metabolizing enzymes. (Republic of Korea) (abst – 2018) https://link.springer.com/article/10.1007/s12272-018-1055-x
Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques? (Germany) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218302971
Identifying and treating patients with synthetic psychoactive drug intoxication. (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/30048361
Fatal Poisonings Associated with New Psychoactive Substances. (Sweden) (abst – 2018) https://link.springer.com/chapter/10.1007%2F164_2018_110
The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonist New Psychoactive Substances: Evolution. (abst – 2018) https://link.springer.com/chapter/10.1007%2F164_2018_144
Psychosis and synthetic cannabinoids. (USA) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0165178117314312?via%3Dihub
Clinical effects of reported synthetic cannabinoid exposure in patients admitted to the intensive care unit. (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/30146395
The Changing Face of Synthetic Cannabinoids in Texas. (abst – 2018) https://www.semanticscholar.org/paper/The-Changing-Face-of-Synthetic-Cannabinoids-in-Maxwell/0c213b26988b04d915eea2c9e172cdfc39421a13
Toxic leukoencephalopathy with extrapyramidal dysfunction due to synthetic cannabinoids. (USA) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0967586818307914
Synthetic cannabinoid isomers characterization by MALDI-MS3 imaging: Application to single scalp hair. (France/ UK) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S000326701831119X
Ischaemic cardiomyopathy and embolic stroke in a young adult with suspected synthetic cannabinoid use. (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29880579
Synthetic cannabinoid use among a sample of individuals enrolled in community-based recovery programs: Are synthetic cannabinoids actually preferred to other drugs? (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/30457960
The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonists as New Psychoactive Substances: Origins. (abst – 2018) https://link.springer.com/chapter/10.1007/164_2018_144
5F-Cumyl-PINACA in ‘e-liquids’ for electronic cigarettes: comprehensive characterization of a new type of synthetic cannabinoid in a trendy product including investigations on the in vitro and in vivo phase I metabolism of 5F-Cumyl-PINACA and its non-fluorinated analog Cumyl-PINACA. (Germany/ Switzerland) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315005/
Review of the many faces of synthetic cannabinoid toxicities. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398358/
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites. (China/ USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409358/
Medicinal use of cannabis based products and cannabinoids. (UK) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447998/
Psychopathological symptoms associated with synthetic cannabinoid use: a comparison with natural cannabis. (Netherlands/ Sweden/ UK/ Spain) (full – 2019) https://link.springer.com/article/10.1007%2Fs00213-019-05238-8
Synthetic Cannabinoids-“Spice” Can Induce a Psychosis: A Brief Review. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450675/
A Case of Acute Life-Threatening Pulmonary Hemorrhage from Synthetic Cannabinoid Abuse. (USA) (full – 2019) https://www.hindawi.com/journals/cripu/2019/8137648/
Delayed Intracerebral Hemorrhage after Synthetic Cannabis (Bonsai) Abuse; Case Report and Literature Review. (Turkey) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681887/
Cannabinoid1 (CB-1) receptor antagonists: a molecular approach to treating acute cannabinoid overdose. (USA) (full – 2019) https://link.springer.com/article/10.1007%2Fs00702-019-02132-7
Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex (USA) (full–2019) https://www.cell.com/cell/fulltext/S0092-8674(18)31565-4
A New Differential Diagnosis: Synthetic Cannabinoid-Associated Gross Hematuria. (USA) (link to full – 2019) https://www.hindawi.com/journals/crim/2019/6327819/
Perfusion Index Analysis in Patients Presenting to the Emergency Department Due to Synthetic Cannabinoid Use. (Turkey) (link to PDF – 2019) https://www.mdpi.com/1010-660X/55/12/752
What are the psychological effects of using synthetic cannabinoids? A systematic review. (UK) (click “uclacuk” for download – 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22What+are+the+psychological+effects+of+using+synthetic+cannabinoids%3F+A+systematic+review.%22&btnG
Osborn wave and new-onset atrial fibrillation related to hypothermia after synthetic cannabis (bonsai) abuse. (Turkey) (abst – 2019) http://archivestsc.com/jvi.aspx?un=TKDA-30513
Use of gas chromatography-mass spectrometry for definitive diagnosis of synthetic cannabinoid toxicity in a dog. (Israel) (abst – 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/vec.12872
Synthetic cannabinoids and endometrial stromal cell fate: Dissimilar effects of JWH-122, UR-144 and WIN55,212-2. (Portugal) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0300483X18303834?via%3Dihub
Cannabis for cancer – illusion or the tip of an iceberg: a review of the evidence for the use of Cannabis and synthetic cannabinoids in oncology. (Israel) (abst – 2019) https://www.tandfonline.com/doi/abs/10.1080/13543784.2019.1561859?journalCode=ieid20
Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases. (USA) (abst – 2019) https://link.springer.com/article/10.1007%2Fs11894-019-0670-0
Synthetic cannabinoid use disorder: an update for general psychiatrists. (Australia) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30663326
Synthetic cannabinoid use among college students. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0306460318308013?via%3Dihub
A case of 5F-ADB / FUB-AMB abuse: Drug-induced or drug-related death? (Bulgaria ) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0379073818310454
Hemorrhagic Soft Tissue Upper Airway Obstruction From Brodifacoum-Contaminated Synthetic Cannabinoid. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0736467919301337
Synthetic cannabinoids and their impact on neurodevelopmental processes. (Portugal) (abst – 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/adb.12824
A case report positive for synthetic cannabinoids: are cardiovascular effects related to their protracted use? (Italy) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S1344622319303049?via%3Dihub
Analysis of synthetic cannabinoids on paper before and after processing for latent print using DFO and ninhydrin. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0379073819304128?via%3Dihub
Spice, vulnerability, and victimization: Synthetic cannabinoids and interpersonal crime victimization among homeless adults. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31697191
Psychotic Disorders in Patients Who Use Synthetic Cannabinoids. (Russia) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31821228
Occurrence of Takotsubo Cardiomyopathy after Synthetic Cannabinoid Consumption. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31839918
Neurological Symptoms and Evaluation of Cerebral Blood Flow Changes with Synthetic Cannabinoids Use. (Turkey) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31839092
Synthetic cannabinoid receptor agonists-induced recurrent seizure in elderly patient. (USA) (abst – 2019) https://www.ajemjournal.com/article/S0735-6757(19)30752-1/fulltext
Adding more “Spice” to the pot; a review of the chemistry and pharmacology of newly emerging heterocyclic synthetic cannabinoid receptor agonists. (Ireland) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31854124
Sexual risk classes among youth experiencing homelessness: Relation to childhood adversities, current mental symptoms, substance use, and HIV testing. (USA) (full – 2020) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227331
Challenges and Opportunities in Preclinical Research of Synthetic Cannabinoids for Pain Therapy. (Romania) (full – 2020) https://www.mdpi.com/1010-660X/56/1/24/htm
Spice intoxication and hyperglycemia. (Spain) (abst in English, link to full in Spanish – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31999272
The Endocannabinoid System and Synthetic Cannabinoids in Preclinical Models of Seizure and Epilepsy. (Canada) (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31895186
The other side of the leaf: Seizures associated with synthetic cannabinoid use. (Australia) (abst – 2020) https://www.epilepsybehavior.com/article/S1525-5050(19)31190-4/fulltext
Uses, Effects and Toxicity of Synthetic Cannabinoids from the Perspective of People with Lived Experiences. (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/32027228
Effect of the UK Psychoactive Substances Act 2016 on episodes of toxicity related to new psychoactive substances as reported to the National Poisons Information Service. A time series analysis. (UK) (abst – 2020) https://www.sciencedirect.com/science/article/abs/pii/S095539592030013X
SR-144528
Spinal and peripheral analgesic effects of the CB cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931557/?tool=pubmed
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871326/
Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties. (full – 2010) http://onlinelibrary.wiley.com/doi/10.1002/eji.201040667/full
Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ9-tetrahydrocannabinol. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967639/
The Levels of the Endocannabinoid Receptor CB2 and Its Ligand 2- Arachidonoylglycerol Are Elevated in Endometrial Carcinoma. (link to PDF – 2010) https://www.researchgate.net/publication/41408306_The_Levels_of_the_Endocannabinoid_Receptor_CB2_and_Its_Ligand_2-Arachidonoylglycerol_Are_Elevated_in_Endometrial_Carcinoma Abnormal-Cannabidiol-Induced Increase in Aqueous Humor Outflow. (abst – 2010) http://iovs.arvojournals.org/article.aspx?articleid=2368788&resultClick=1
CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling (full – 2011) http://www.jbc.org/content/287/2/1198.full
Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388539/
N-arachidonoyl–serine is neuroprotective after traumatic brain injury by reducing apoptosis. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170948/
Self-medication of a cannabinoid CB(2) agonist in an animal model of neuropathic pain. (full – 2011) http://europepmc.org/articles/PMC3157548
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182059/
Functional selectivity in CB2 cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB2 ligands. (full – 2011) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263955/
Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model (link to PDF–2011) http://jpet.aspetjournals.org/content/early/2011/06/14/jpet.111.182717.long
The effect of CBD (BDS) botanical cannabinoid extraction on MCF-7 human breast carcinoma cells. (abst – 2011) http://eprints.hud.ac.uk/16197/
Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice. (abst – 2011) https://www.ncbi.nlm.nih.gov/pubmed/21771590
The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level. (full – 2012) http://journals.lww.com/anesthesia-analgesia/Fulltext/2012/06000/The_Effects_of_Peptide_and_Lipid_Endocannabinoids.30.aspx
Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists. (full – 2012) http://onlinelibrary.wiley.com/doi/10.1002/jbmr.1732/full
Excitability of prefrontal cortical pyramidal neurons is modulated by activation of 98 intracellular type-2 cannabinoid receptors. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295302/
Cannabinoid Receptor 2 Signaling in Peripheral Immune Cells Modulates Disease Onset and Severity in Mouse Models of Huntington’s Disease. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753072/
WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway. (link to PDF – 2012) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=WIN55212-2+attenuates+amyloid-beta-
induced+neuroinflammation+in+rats+through+activation+of+cannabinoid+receptors+and+PPAR-%CE%B3+pathway.+++&btnG= Effect of Oleoylethanolamide on Aqueous Humor Outflow. (abst – 2012) http://iovs.arvojournals.org/article.aspx?articleid=2352002&resultClick=1
Stabilization of Functional Recombinant Cannabinoid Receptor CB2 in Detergent Micelles and Lipid Bilayers. (full – 2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0046290
Characterization of cannabinoid receptor ligands in tissues natively expressing cannabinoid CB2 receptors. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687668/
Endocannabinoids as markers of sperm quality: hot spots. (full – 2013) http://www.frontiersin.org/Journal/10.3389/fendo.2013.00169/full
Cannabinoid Receptor 2 (CB2) Plays a Role in the Generation of Germinal Center and Memory B Cells, but Not in the Production of Antigen-Specific IgG and IgM, in Response to T-dependent Antigens. (full – 2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067587
Blockade of cannabinoid receptors reduces inflammation, leukocyte accumulation and neovascularization in a model of sponge-induced inflammatory angiogenesis. (link to PDF – 2013) https://www.researchgate.net/publication/236977025_Blockade_of_cannabinoid_receptors_reduces_inflammation_leukocyte_accumu
lation_and_neovascularization_in_a_model_of_sponge-induced_inflammatory_angiogenesis Sex differences in anti-allodynic, anti-hyperalgesic and anti-edema effects of Δ9- tetrahydrocannabinol in the rat. (click “theroc” for download – 2013) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Sex+differences+in+anti-allodynic%2C+anti-hyperalgesic+and+anti-
edema+effects+of+%CE%94%289%29-tetrahydrocannabinol+in+the+rat.&btnG Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S0968089613000941
Effects of the cannabinoid 2 receptor-selective agonist GW405833 in assays of acute pain-stimulated and paindepressed behavior in rats. (abst – 2013) https://www.fasebj.org/doi/10.1096/fasebj.27.1_supplement.886.9
The role of Cannabinoid receptors on light-induced photoreceptor degeneration. (abst – 2013) http://iovs.arvojournals.org/article.aspx?articleid=2149928&resultClick=1
The effect of CBG (BDS) botanical cannabinoid extract on MCF-7 human breast carcinoma cells. (abst – 2013) https://www.fasebj.org/doi/10.1096/fasebj.27.1_supplement.1105.21
Characterisation of cannabinoid-induced relief of neuropathic pain in a rat model of cisplatin-induced neuropathy. (abst – 2013) http://www.sciencedirect.com/science/article/pii/S0091305713000440
Antagonism of cannabinoid receptor 2 pathway suppresses IL-6-induced immunoglobulin IgM secretion. (full – 2014) http://www.biomedcentral.com/2050-6511/15/30
Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1 receptors. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243853/
Examining the critical roles of human CB2 receptor residues Valine 3.32 (113) and Leucine 5.41 (192) in ligand recognition and downstream signaling activities. (full – 2014) http://www.sciencedirect.com/science/article/pii/S0006291X14014636
TRPV1 mediates cellular uptake of anandamide and thus promotes endothelial cell proliferation and network-formation. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265754/
Cannabinoid type 2 receptor stimulation attenuates brain edema by reducing cerebral leukocyte infiltration following subarachnoid hemorrhage in rats (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067767/
Chronic activation of CB2 cannabinoid receptors in the hippocampus increases excitatory synaptic transmission. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398527/
Dual inhibition of monoacylglycerol lipase and cyclooxygenases synergistically reduces neuropathic pain in mice. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376450/
2-Arachidonoylglycerol enhances platelet formation from human megakaryoblasts. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614031/
Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy. (full – 2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457709/
Detailed characterization of the endocannabinoid system in human macrophages and foam cells, and anti-inflammatory role of type-2 cannabinoid receptor (link to PDF–2014) https://www.researchgate.net/publication/259995010_Detailed_characterization_of_the_endocannabinoid_system_in_human_macrophages_and_foam_cells_and_anti-inflammatory_role_of_type-2_cannabinoid_receptor
Blockade of cannabinoid CB1 and CB2 receptors does not prevent the antipruritic effect of systemic paracetamol. (link to PDF – 2014) https://www.researchgate.net/publication/259627237_Blockade_of_cannabinoid_CB1_and_CB2_receptors_does_not_prevent_the_an
tipruritic_effect_of_systemic_paracetamol Attenuation of serotonin-induced itch responses by inhibition of endocannabinoid degradative enzymes, fatty acid amide hydrolase and monoacylglycerol lipase. (link to PDF – 2014) https://www.researchgate.net/publication/263015216_Attenuation_of_serotonin-
induced_itch_responses_by_inhibition_of_endocannabinoid_degradative_enzymes_fatty_acid_amide_hydrolase_and_monoacylglycer ol_lipase Inhibition of Peripheral Fatty Acid Amide Hydrolase Depresses Activities of Bladder Mechanosensitive Nerve Fibers of the Rat. (abst – 2014) https://www.sciencedirect.com/science/article/pii/S0022534714033345
Ultralow doses of cannabinoid drugs protect the mouse brain from inflammation-induced cognitive damage. (abst – 2014) https://www.semanticscholar.org/paper/Ultralow-doses-of-cannabinoid-drugs-protect-the-Fishbein-Kaminietsky-
Gafni/7543d1bbca2aa3d39ca4d5a241be95912881acb8 Type-2 cannabinoid receptor regulates proliferation, apoptosis, differentiation, and OPG/RANKL ratio of MC3T3-E1 cells exposed to Titanium particles. (abst – 2014) https://www.semanticscholar.org/paper/Type-2-cannabinoid-receptor-regulates-apoptosis%2C-of-Qiu-
Zhao/5a89fe2f51f15a5b351be82fa4902fe4afad7e56 Interaction of a Cannabinoid-2 Agonist With Tramadol on Nociceptive Thresholds and Immune Responses in a Rat Model of Incisional Pain. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25370921
Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477849/
Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti- inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages. (Netherlands) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1111/bph.12747/full
Bi-directional CB1 receptor-mediated cardiovascular effects of cannabinoids in anaesthetized rats: role of the paraventricular nucleus (Poland/Germany) (full–2015) http://jpp.krakow.pl/journal/archive/06_15/articles/03_article.html
A Cannabinoid Receptor 2 Agonist Prevents Thrombin-Induced Blood-Brain Barrier Damage via the Inhibition of Microglial Activation and Matrix Metalloproteinase Expression in Rats. (China) (link to PDF – 2015) https://www.researchgate.net/publication/282044189_A_Cannabinoid_Receptor_2_Agonist_Prevents_Thrombin-Induced_Blood-Brain_Barrier_Damage_via_the_Inhibition_of_Microglial_Activation_and_Matrix_Metalloproteinase_Expression_in_Rats
Cannabinoid CB2 receptor stimulation attenuates brain edema and neurological deficits in a germinal matrix hemorrhage rat model (China) (link to download–2015) https://www.academia.edu/20365063/Cannabinoid_CB2_receptor_stimulation_attenuates_brain_edema_and_neurological_deficits_in_a_germinal_matrix_hemorrhage_rat_model
S-777469, a Novel Cannabinoid Type 2 Receptor Agonist, Suppresses Itch-Associated Scratching Behavior in Rodents through Inhibition of Itch Signal Transmission. (Japan) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25721168
Spinal neuronal cannabinoid receptors mediate urodynamic effects of systemic fatty acid amide hydrolase (FAAH) inhibition in rats (Germany/Italy/Sweden) (abst–2015) https://www.semanticscholar.org/paper/Spinal-neuronal-cannabinoid-receptors-mediate-of-in-Fuellhase-Schreiber/b51a4ef67ea5b2fd72f077e6f48e4ed1e7202efe
Cannabinoid Receptor Type 2 Agonist Attenuates Acute Neurogenic Pulmonary Edema by Preventing Neutrophil Migration after Subarachnoid Hemorrhage in Rats. (China) (abst – 2015) https://www.sciencedirect.com/science/article/pii/S0006899315000451
Intracellular postsynaptic cannabinoid receptors link thyrotropin-releasing hormone receptors to TRPC-like channels in thalamic paraventricular nucleus neurons. (Canada) (abst – 2015) https://www.sciencedirect.com/science/article/abs/pii/S0306452215009227
Endocannabinoid Inhibition Of Airway Sensory Nerve Depolarisation (UK) (abst–2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4114
Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent. (USA) (full – 2016) https://www.dovepress.com/modulation-of-breast-cancer-cell-viability-by-a-cannabinoid-receptor-2-peer-reviewed-fulltext-article-BCTT
Vascular Dysfunction in a Transgenic Model of Alzheimer’s Disease: Effects of CB1R and CB2R Cannabinoid Agonists. (Spain) (full – 2016) http://journal.frontiersin.org/article/10.3389/fnins.2016.00422/full
The CB2 receptor and its role as a regulator of inflammation. (Canada) (full – 2016) http://link.springer.com/article/10.1007%2Fs00018-016-2300-4
Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen- induced pulmonary inflammation in mice. (Austria/ Sweden) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225803/
Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice. (Austria) (full – 2016) http://www.sciencedirect.com/science/article/pii/S0021915015301933
Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke. (Spain) (full – 2016) http://stroke.ahajournals.org/content/48/1/204.long
Functional selectivity of CB2 cannabinoid receptor ligands at a canonical and non- canonical pathway. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959096/
The endocannabinoid system and NGF are involved in the mechanism of action of resveratrol: a multi-target nutraceutical with therapeutic potential in neuropsychiatric disorders. (Iran) (link to PDF – 2016) https://www.researchgate.net/publication/291185238_The_endocannabinoid_system_and_NGF_are_involved_in_the_mechanism_of_action_of_resveratrol_A_multi-target_nutraceutical_with_therapeutic_potential_in_neuropsychiatric_disorders Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth. (USA) (ignore error message) (download – 2016) http://www.jbc.org/content/early/2016/02/21/jbc.M115.707836.long
Δ9-Tetrahydrocannabinol Reverses TNFα-induced Increase in Airway Epithelial Cell Permeability through CB2 Receptors. (UK) (click “nottinghamacuk” for download–2016) https://scholar.google.com/scholar?q=%CE%949-Tetrahydrocannabinol+reverses+TNF%CE%B1-induced+increase+in+airway+epithelial+cell+permeability+through+CB2+receptors&hl=en&as_sdt=0&as_vis=1&oi=scholart
Cannabinoid Receptor 2 Activation Restricts Fibrosis and Alleviates Hydrocephalus after Intraventricular Hemorrhage. (China) (click “researchgate” for download–2016) https://scholar.google.com/scholar?q=Cannabinoid+Receptor+2+Activation+Restricts+Fibrosis+and+Alleviates+Hydrocephalus+after+Intraventricular+Hemorrhage.&hl=en&as_sdt=0&as_vis=1&oi=scholart Cannabinoid Receptor Type 2 Agonist Attenuates Acute Neurogenic Pulmonary Edema by Preventing Neutrophil Migration after Subarachnoid Hemorrhage in Rats. (USA/ Japan) (abst-2016) http://link.springer.com/chapter/10.1007/978-3-319-18497-5_24
Inflammatory Regulation by Driving Microglial M2 Polarization: Neuroprotective Effects of Cannabinoid Receptor-2 Activation in Intracerebral Hemorrhage. (China) (full – 2017) http://journal.frontiersin.org/article/10.3389/fimmu.2017.00112/full
Compensatory Activation of Cannabinoid CB2 Receptor Inhibition of GABA Release in the Rostral Ventromedial Medulla in Inflammatory Pain. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242409/
Cannabinoid Modulation of Memory Consolidation in Rats: Beyond the Role of Cannabinoid Receptor Subtype 1. (Italy) (full – 2017) http://journal.frontiersin.org/article/10.3389/fphar.2017.00200/full
Bladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism. (Italy/ USA) (full – 2017) http://www.nature.com/articles/srep42157
Anti-Inflammatory Activity in Colon Models Is Derived from Δ9- Tetrahydrocannabinolic Acid That Interacts with Additional Compounds in Cannabis Extracts. (Israel) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627671/
Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB2 Receptors. (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660261/
Activation of cannabinoid receptor type 2 by JWH133 alleviates bleomycin-induced pulmonary fibrosis in mice. (China) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732744/
Cannabinoids Regulate the Diameter of Pericyte-Containing Retinal Capillaries in Rats (China) (full–2017) https://www.karger.com/Article/FullText/484193
The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice. (USA/ Turkey/ Saudi Arabia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558428/
Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. (USA/ Australia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363769/
Antinociceptive effects of JWH015 in female and male rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849479/
Anti-migraine effect of ∆9-tetrahydrocannabinol in the female rat. (USA) (link to PDF – 2017) https://www.researchgate.net/publication/320687020_Anti-migraine_effect_of_9_-tetrahydrocannabinol_in_the_female_rat
Analysis of Natural Product Regulation of Cannabinoid Receptors in the treatment of Human Disease. (USA/ Jamaica) (click “researchgate” for download – 2017) https://scholar.google.com/scholar?q=Analysis+of+natural+product+regulation+of+cannabinoid+receptors+in+the+treatment+of+human+disease.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Involvement of cannabinoid receptor type 2 in light-induced degeneration of cells from mouse retinal cell line in vitro and mouse photoreceptors in vivo (Japan) (abst–2017) http://www.sciencedirect.com/science/article/pii/S0014483516304456
https://www.semanticscholar.org/paper/Involvement-of-cannabinoid-receptor-type-2-in-of-in-Imamura-Tsuruma/9317b8cbb10ee32ea8e98a3de52394f81d30f02e Celastrol alleviates renal fibrosis by upregulating cannabinoid receptor 2 expression. (China) (full – 2018) https://www.nature.com/articles/s41419-018-0666-y
Role of CB2 Receptor in the Recovery of Mice after Traumatic Brain Injury (Israel) (full–2018) https://www.researchgate.net/publication/329294669_The_Role_of_CB2_Receptor_in_the_Recovery_of_Mice_after_Traumatic_Brain_Injury
Oxidative burst and Dectin-1 triggered phagocytosis affected by Norepinephrine and Endocannabinoids – Implications for fungal clearance under stress (Germany/UK) (link to PDF–2018) https://www.researchgate.net/publication/322476069_Oxidative_burst_and_Dectin-
1_triggered_phagocytosis_affected_by_Norepinephrine_and_Endocannabinoids_-_Implications_for_fungal_clearance_under_stress
The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis. (Portugal) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0378427418300377
A cannabinoid receptor 2 agonist reduces blood-brain barrier damage via induction of MKP-1 after intracerebral hemorrhage in rats. (China) (abst 2018) https://www.sciencedirect.com/science/article/pii/S0006899318303330?via%3Dihub
Targeting the cannabinoid receptor CB2 in a mouse model of l-dopa induced dyskinesia. (Australia) (full – 2019) https://www.sciencedirect.com/science/article/pii/S0969996119303213?via%3Dihub
Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay. (China/ UK) (full – 2019) https://www.sciencedirect.com/science/article/pii/S0378874119315569
Reduced cannabinoid 2 receptor activity increases susceptibility to induced seizures in mice. (USA) (abst – 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.16388
SSR411298
The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents. (France) (full – 2018) https://www.nature.com/articles/s41598-018-20895-z
ST-4070
Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety. (Italy) (full – 2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137034
SUGAR/FRUCTOSE
Modulation of sweet taste sensitivity by orexigenic and anorexigenic factors. (link to download – 2010) https://www.jstage.jst.go.jp/article/endocrj/57/6/57_K10E-095/_pdf
Fructose affects enzymes involved in the synthesis and degradation of hypothalamic endocannabinoids. (abst – 2010) https://www.semanticscholar.org/paper/Fructose-affects-enzymes-involved-in-the-synthesis-Erlanson-Albertsson-
Lindqvist/1f677a0ca3f267534165e626184012bb8fb7d925 Nonalcoholic fatty liver disease: pathology and pathogenesis. (abst – 2010) https://www.ncbi.nlm.nih.gov/pubmed/20078219
Pathophysiology of Human Visceral Obesity: An Update. (full – 2013) http://physrev.physiology.org/content/93/1/359.long
Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats (link to PDF–2013) https://www.researchgate.net/publication/259110453_Preventive_and_treatment_effects_of_a_hemp_seed_Cannabis_sativa_L_meal_protein_hydrolysate_against_high_blood_pressure_in_spontaneously_hypertensive_rats
Effects of high-fructose diets on central appetite signaling and cognitive function. (Belgium) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429636/
Management of non-alcoholic fatty liver disease in 2015. (Canada) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691699/
Metabolic effects of intermittent access to caloric or non-caloric sweetened solutions in mice fed a high-caloric diet. (France) (abst – 2017) https://www.sciencedirect.com/science/article/abs/pii/S0031938416311982
Metabolic Syndrome Induced Bladder Cannabinoid Receptor Changes in the Fructose- Fed Rats. (Taiwan) (abst – 2017) https://www.semanticscholar.org/paper/Metabolic-Syndrome-Induced-Bladder-Cannabinoid-in-Chen-Cheng/5a295e8e6ec6093333ea3d8d3d757b3c426c749f
Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII and ApoE in humans consuming high fructose corn syrup-sweetened beverage (USA) (full-2018) https://www.physiology.org/doi/abs/10.1152/ajpendo.00406.2017
SUGAR/GLUCOSE
N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119. (full – 2010) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428146/
Endocannabinoids selectively enhance sweet taste. (full – 2010) http://www.pnas.org/content/107/2/935.long
Modulation of sweet taste sensitivity by orexigenic and anorexigenic factors. (link to download – 2010) https://www.jstage.jst.go.jp/article/endocrj/57/6/57_K10E-095/_pdf
The role of small molecule GPR119 agonist, AS1535907, in glucose-stimulated insulin secretion and pancreatic β-cell function. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/21114601
GPR119 Regulates Murine Glucose Homeostasis Through Incretin Receptor-Dependent and Independent Mechanisms. (full – 2011) http://endo.endojournals.org/content/152/2/374.full?sid=c7413b30-1046-4f9c-b028-c46f78f293d9
Central Endocannabinoid Signaling Regulates Hepatic Glucose Production and Systemic Lipolysis. (full – 2011) http://diabetes.diabetesjournals.org/content/60/4/1055.full
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells. (full – 2011) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064093/
TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats (click “semanticscholar” for download–2011) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=TAK-875%2C+an+orally+available+G+protein-coupled+receptor+40%2Ffree+fatty+acid+receptor+1+agonist%2C+enhances+glucose-dependent+insulin+secretion+and+improves+both+postprandial+and+fasting+hyperglycemia+in+type+2+diabetic+rats.+++++++++ &btnG
Relationships between glucose, energy intake and dietary composition in obese adults with type 2 diabetes receiving the cannabinoid 1 (CB1) receptor antagonist, rimonabant (full–2012) http://www.nutritionj.com/content/11/1/50
Does rimonabant independently affect free fatty acid and glucose metabolism? (full–2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319222/
Induction of Glucose Intolerance by Acute Administration of Rimonabant. (click “academia” for download – 2012) https://scholar.google.com/scholar?q=Induction+of+glucose+intolerance+by+acute+administration+of+rimonabant.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Optimization of (2,3-dihydro-1-benzofuran-3-yl)acetic acids: discovery of a non-free fatty acid-like, highly bioavailable G protein-coupled receptor 40/free fatty acid receptor 1 agonist as a glucose-dependent insulinotropic agent. (abst – 2012) https://pubs.acs.org/doi/abs/10.1021/jm300170m
Impaired hippocampal glucoregulation in the cannabinoid CB(1) receptor knockout mice as revealed by an optimized in vitro experimental approach. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S0165027011007059
https://www.semanticscholar.org/paper/Impaired-hippocampal-glucoregulation-in-the-mice-as-Lemos-Val%C3%A9rio-Fernandes/a48552a6336897df227443e722fbedfb702096c3
The impact of marijuana use on glucose, insulin, and insulin resistance among US adults. (full – 2013) http://www.amjmed.com/article/S0002-9343%2813%2900200-3/fulltext
Developmental Role for Endocannabinoid Signaling in Regulating Glucose Metabolism and Growth. (full – 2013) http://diabetes.diabetesjournals.org/content/62/7/2359.full?sid=2f5bda2b-a9c7-432a-9588-80c99189164d
Docosahexaenoyl ethanolamide improves glucose uptake and alters endocannabinoid system gene expression in proliferating and differentiating C2C12 myoblasts. (full – 2014) http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00100/full
α/β-Hydrolase Domain-6-Accessible Monoacylglycerol Controls Glucose-Stimulated Insulin Secretion. (full – 2014) http://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00166-1
The G-Protein-Coupled Long-Chain Fatty Acid Receptor GPR40 and Glucose Metabolism. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176464/
Glucose concentration in culture medium affects mRNA expression of TRPV1 and CB1 receptors and changes capsaicin toxicity in PC12 cells. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322151/
Glucose metabolism: Focus on gut microbiota, the endocannabinoid system and beyond. (click “uclouvain” for download – 2014) https://scholar.google.com/scholar?q=Glucose+metabolism:+focus+on+gut+microbiota,+the+endocannabinoid+system+and+beyond.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Mechanism of endocannabinoids system in glucose metabolism of rats with chronic intermittent hypoxia. (abst in English – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25146750 (abst in Chinese – 2014) http://zhyxzz.yiigle.com/CN112137201420/561542.htm?locale=zh_CN
Fractionation of hemp hurds by organosolv pretreatment and its effect on production of lignin and sugars. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24753480
Cannabinoid CB1 receptors and mTORC1 signalling pathway interact to modulate glucose homeostasis. (Spain/ France) (full – 2015) http://dmm.biologists.org/content/9/1/51.long
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722239/
Changes in Plasma Levels of N-Arachidonoyl Ethanolamine and N- Palmitoylethanolamine following Bariatric Surgery in Morbidly Obese Females with Impaired Glucose Homeostasis. (UK) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385619/
Cannabidiol protects an in vitro model of the blood brain barrier (BBB) from oxygen- glucose deprivation via PPARγ and 5-HT1A. (UK) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761095/
G protein-coupled receptors: signalling and regulation by lipid agonists for improved glucose homoeostasis. (UK) (abst – 2015) https://link.springer.com/article/10.1007%2Fs00592-015-0826-9
https://www.semanticscholar.org/paper/G-protein-coupled-receptors%3A-signalling-and-by-for-Moran-Flatt/c4624325c85b1138cbe2b39172e152e31ad50ae5
Mechanisms underlying glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 secretion. (UK) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854499/
Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer’s disease. (Portugal/ Spain/ Argentina) (full – 2016) http://www.sciencedirect.com/science/article/pii/S0028390816300879
Dysregulation of the endocannabinoid signaling system in the cerebellum and brainstem in a transgenic mouse model of spinocerebellar ataxia type-3 (Spain/ Portugal/ USA) (click “uminhopt” for download–2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Dysregulation+of+the+endocannabinoid+signaling+system+in+the+cerebellum+and+brainstem+in+a+transgenic+mouse+model+of+spinocerebellar+ataxia+type-3.+++++++++++++++%22&btnG
The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet- induced obese pre-diabetic mice. (Spain/ UK/ Brazil) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479807/
Mice expressing a “hyper-sensitive” form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398885/
GPR55 and the regulation of glucose homeostasis. (Spain) (link to PDF – 2017) https://www.researchgate.net/publication/316529366_GPR55_and_the_regulation_of_glucose_homeostasis
Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy. (USA) (download – 2017) http://publicatio.bibl.u-szeged.hu/13595/1/Jourdan_DiabetesObsityMetabolism_2017.pdf
Effects of tetrahydrocannabinol on glucose uptake in the rat brain. (Germany) (abst–2017) http://www.sciencedirect.com/science/article/pii/S0028390817300564
Blockade of cannabinoid 1 receptor improves glucose responsiveness in pancreatic beta cells. (Republic of Korea/ USA) (full – 2018) http://onlinelibrary.wiley.com/doi/10.1111/jcmm.13523/full
The Endocannabinoid System Affects Myocardial Glucose Metabolism in the DOCA- Salt Model of Hypertension. (Poland) (full – 2018) https://www.karger.com/Article/FullText/488730
Positron emission tomography imaging of cerebral glucose metabolism and type 1 cannabinoid receptor availability during temporal lobe epileptogenesis in the amygdala kindling model in rhesus monkeys. (Belgium) (full – 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.14059
Multiple Sclerosis, Cannabis Use, and Clinical Disability: A Preliminary [18F]- Fluorodeoxyglucose Positron Emission Tomography Study. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186162/
Effects of cannabis use on body mass, fasting glucose and lipids during the first 12 months of treatment in schizophrenia spectrum disorders. (South Africa/ UK) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0920996418301282?via%3Dihub
Spermidine prevents high glucose-induced senescence in HT-22 cells by upregulation of CB1 receptor. (China) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29699000
Joint and separate exposure to alcohol and ∆9-tetrahydrocannabinol produced distinct effects on glucose and insulin homeostasis in male rats. (USA) (full – 2019) https://www.nature.com/articles/s41598-019-48466-w
Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis. (Germany) (full – 2019) https://www.mdpi.com/
1422-0067/20/10/2516/htm The TRPV1 channel regulates glucose metabolism. (Australia) (abst – 2019) https://www.physiology.org/doi/abs/10.1152/ajpendo.00102.2019
Combined Loss of Ghrelin Receptor and Cannabinoid CB1 Receptor in Mice Decreases Survival but Does Not Additively Reduce Body Weight or Eating (USA) (abst–2019) https://www.sciencedirect.com/science/article/abs/pii/S0306452219306505?via%3Dihub
PipeNig®-FL, a Fluid Extract of Black Pepper (Piper Nigrum L.) with a High Standardized Content of Trans-β-Caryophyllene, Reduces Lipid Accumulation in 3T3-L1 Preadipocytes and Improves Glucose Uptake in C2C12 Myotubes (Italy) (abst–2019) https://www.ncbi.nlm.nih.gov/pubmed/31731718
The Effects of Chronic Δ-9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD) use on Cerebral Glucose Metabolism in Multiple Sclerosis: A Pilot Study. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31841355
Glucose Increase DAGLα Levels in Tanycytes and Its Inhibition Alters Orexigenic and Anorexigenic Neuropeptides Expression in Response to Glucose. (Chile) (full – 2020) https://www.frontiersin.org/articles/10.3389/fendo.2019.00647/full
The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling. (UK) (full – 2020) https://link.springer.com/article/10.1007%2Fs00018-019-03433-6
SUGAR/SUCROSE
Voluntary Exercise and Sucrose Consumption Enhance Cannabinoid CB1 Receptor Sensitivity in the Striatum. (full – 2010) http://www.nature.com/npp/journal/v35/n2/full/npp2009141a.html
Endocannabinoids selectively enhance sweet taste. (full – 2010) http://www.pnas.org/content/107/2/935.long
Fructose affects enzymes involved in the synthesis and degradation of hypothalamic endocannabinoids. (abst – 2010) https://www.semanticscholar.org/paper/Fructose-affects-enzymes-involved-in-the-synthesis-Erlanson-Albertsson-
Lindqvist/1f677a0ca3f267534165e626184012bb8fb7d925 Cannabinoid facilitation of behavioral and biochemical hedonic taste responses. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705914/
Stimulation of acumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats. (abst – 2012) http://www.sciencedirect.com/science/article/pii/S1043661812001223
Rimonabant reduces the essential value of food in the genetically obese Zucker rat: An exponential demand analysis. (abst – 2012) https://www.sciencedirect.com/science/article/abs/pii/S0031938411004860?via%3Dihub
Rimonabant’s reductive effects on high densities of food reinforcement, but not palatability, in lean and obese Zucker rats. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036064/
The effects of leptin in combination with a cannabinoid receptor 1 antagonist, AM 251, or cannabidiol on food intake and body weight in rats fed a high-fat or a free-choice high sugar diet. (link to download – 2014) http://www.jpp.krakow.pl/journal/archive/08_14/pdf/487_08_14_article.pdf
Quantitative analysis of performance on a progressive-ratio schedule: effects of reinforcer type, food deprivation and acute treatment with Δ9-tetrahydrocannabinol (THC). (UK) (full – 2015) http://www.sciencedirect.com/science/article/pii/S037663571500042X
Genetic Versus Pharmacological Assessment of the Role of Cannabinoid Type 2 Receptors in Alcohol Reward-Related Behaviors. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886733/
Cannabinoid CB1 receptor inhibition blunts adolescent-typical increased binge alcohol and sucrose consumption in male C57BL/6J mice. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905821/
Cannabinoid-glutamate interactions in the regulation of food intake in neonatal layer- type chicks: role of glutamate NMDA and AMPA receptors. (Iran) (abst – 2016) https://link.springer.com/article/10.1007%2Fs11259-016-9655-8
https://www.semanticscholar.org/paper/Cannabinoid%E2%80%93glutamate-interactions-in-the-of-food-Keyshams-Zendehdel/7d3ba181d16df85ebba84aab9265724f3e95c76f
Effects of Adolescent Cannabinoid Self-Administration in Rats on Addiction-Related Behaviors and Working Memory. (USA) (full – 2017) https://www.nature.com/articles/npp2016178
Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790819/
A behavioral and pharmacological characterization of palatable diet alternation in mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911178/
Metabolic effects of intermittent access to caloric or non-caloric sweetened solutions in mice fed a high-caloric diet. (France) (abst – 2017) https://www.sciencedirect.com/science/article/abs/pii/S0031938416311982
Suppressing effect of COR659 on alcohol, sucrose, and chocolate self-administration in rats: involvement of the GABAB and cannabinoid CB1 receptors (Italy) (abst–2017) https://link.springer.com/article/10.1007%2Fs00213-017-4644-3
Impact of maternal western diet-induced obesity on offspring mortality and peripheral endocannabinoid system in mice. (USA) (full – 2018) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205021
Endocannabinoid-Enhanced “Liking” in Nucleus Accumbens Shell Hedonic Hotspot Requires Endogenous Opioid Signals. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069591/
Structural equation modeling of food craving across the menstrual cycle using behavioral, neuroendocrine, and metabolic factors. (USA) (click “uswracir” for download – 2018) https://scholar.google.com/scholar?q=%22Structural+equation+modeling+of+food+craving+across+the+menstrual+cycle+using+behavioral,+neuroendocrine,+and+metabolic+factors%22&hl=en&as_sdt=0&as_vis=1&oi=scholart
Cannabinoid and nicotine exposure during adolescence induces sex-specific effects on anxiety- and reward-related behaviors during adulthood (Netherlands/USA) (full–2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354968/
Do Endocannabinoids Regulate Glucose Reabsorption in the Kidney? (Israel) (full–2019) https://www.karger.com/Article/FullText/494512
Rapid and Concomitant Gut Microbiota and Endocannabinoidome Response to Diet- Induced Obesity in Mice. (Canada/ Italy) (full – 2019) https://msystems.asm.org/content/4/6/e00407-19
SURINABANT/SR 147778
Concomitant consumption of marijuana, alcohol and tobacco in oral squamous cell carcinoma development and progression: Recent advances and challenges. (click “sdclucknow” for download–2012) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Concomitant+consumption+of+marijuana%2C+alcohol+and+tobacco+in+oral+squamous+cell+carcinoma+development+and+progression%3A+Recent+advances+and+challenges&btnG=
Surinabant, a selective CB(1) antagonist, inhibits THC-induced central nervous system and heart rate effects in humans. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703229/
SYNDROS
Schedule II Schedules of Controlled Substances: Placement of FDA-Approved Products of Oral Solutions Containing Dronabinol [(-)-delta-9-trans-tetrahydrocannabinol (delta-9-THC)] in Schedule II (press release–2017) https://www.federalregister.gov/documents/2017/03/23/2017-05809/schedules-of-controlled-substances-placement-of-fda-approved-products-of-oral-solutions-containing
Schedules of Controlled Substances: Placement of FDA-Approved Products of Oral Solutions Containing Dronabinol [(-)-delta-9-trans- tetrahydrocannabinol (delta-9-THC)] in Schedule II. Final rule. (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/29232070
SYNTHETIC CBD
Report of Objective Clinical Responses of Cancer Patients to Pharmaceutical-grade Synthetic Cannabidiol. (UK) (full – 2018) http://ar.iiarjournals.org/content/38/10/5831.long
Pharmacokinetics and Tolerability of Multiple Doses of Pharmaceutical-Grade Synthetic Cannabidiol in Pediatric Patients with Treatment-Resistant Epilepsy. (USA/ Belgium) (full – 2019) https://link.springer.com/article/10.1007%2Fs40263-019-00624-4
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Updated 25 May 2020
Granny Storm Crow's List 