A (Synthetics Pre-2010)

SYNTHETICS and COMPOUNDS THAT AFFECT the ENDOCANNABINOID SYSTEM Pre-2010

ABN-CBD/ABNORMAL CANNABIDIOL/CAY10429 (GPR-18 / GPR-55 Agonist)
ACEA/ARACHIDONYL-2′-CHLOROETHYLAMIDE (CB1 Agonist)
ACPA/ARACHIDONYLCYCLOPROPYLAMIDE (Potent CB1 Agonist)
AJULEMIC ACID/AjA/IP-751/HU-239/CT-3
AM-111/D-JNKI-1/XG-102 (Blocks MAPK-JNK Signal Pathway)
AM-251 (GPR 55 Agonist, CB1 Antagonist / Inverse Agonist)
AM-281 (CB1 Antagonist and Inverse Agonist)
AM-404 (Cannabinoid Transport Inhibitor, Made in the Body From Acetaminophen, See Also ACETAMINOPHEN)
AM-630 (CB2 Inverse Agonist)
AM-1172 (Anandamide Transport Inhibitor)
AM-1241 (CB 2 Agonist)
AM-1710 (CB2 Agonist)
AM-2233
AM-2389 (CB1 Agonist)
AM-4054
AM-4113 (CB1 Antagonist)
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ABN-CBD/ABNORMAL CANNABIDIOL/CAY10429
Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery (full-2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573773/?tool=pmcentrez
Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor (full–2003) http://molpharm.aspetjournals.org/content/63/3/699.long
2-Arachidonylglyceryl ether and abnormal cannabidiol-induced vascular smooth muscle relaxation in rabbit pulmonary arteries via receptor-pertussis toxin sensitive G proteins-ERK1/2 signaling (abst–2007) http://www.ncbi.nlm.nih.gov/pubmed/17292352
Identification of the vasodilatory endothelial cannabinoid receptor in the human pulmonary artery (abst–2007) http://www.ncbi.nlm.nih.gov/pubmed/17921818
Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: evidence for a site distinct from CB1 and CB2 (full-2008) http://molpharm.aspetjournals.org/content/73/2/441.long
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2 (full-2010) http://pharmrev.aspetjournals.org/content/62/4/588.full.pdf+html
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ACEA/ARACHIDONYL-2′-CHLOROETHYLAMIDE
Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1) (full–1999) http://jpet.aspetjournals.org/content/289/3/1427.long
Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity (abst–2001) http://www.ncbi.nlm.nih.gov/pubmed/11828716
The cannabinoids R(-)-7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl (HU-210), 2-O-arachidonoylglycerylether (HU-310) and arachidonyl-2-chloroethylamide (ACEA) increase isoflurane provoked sleep duration by activation of cannabinoids 1 (CB1)-receptors in mice (abst–2002) http://www.ncbi.nlm.nih.gov/pubmed/12095655
In vivo effects of CB1 receptor ligands on lipid peroxidation and antioxidant defense systems in the rat brain of healthy and ethanol-treated rats (full–2006) http://www.if-pan.krakow.pl/pjp/pdf/2006/6_876.pdf
Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain (full–2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769340/?tool=pubmed
Arachidonyl-2′-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshock-induced seizure model (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/16930590
Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence (full–2007) http://jpet.aspetjournals.org/content/322/3/1144.long
Ultra-low dose cannabinoid antagonist AM251 enhances cannabinoid anticonvulsant effects in the pentylenetetrazole-induced seizure in mice (abst–2007) http://www.ncbi.nlm.nih.gov/pubmed/17870135
Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells (full–2008) http://molpharm.aspetjournals.org/content/74/1/20.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT#content-block
Cannabinoid modulation of cutaneous Adelta nociceptors during inflammation (full–2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585399/?tool=pubmed
Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees (full–2008) http://onlinelibrary.wiley.com/doi/10.1002/art.23156/full
Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling (full–2008) http://www.fasebj.org/content/22/10/3685.long
Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha-mediated ceramide de novo synthesis in colon cancer cells (full–2008) http://clincancerres.aacrjournals.org/content/14/23/7691.long
Additive Interaction of the Cannabinoid Receptor I Agonist Arachidonyl-2-chloroethylamide with Etomidate in a Sedation Model in Mice (full–2008) http://journals.lww.com/anesthesiology/Fulltext/2008/04000/Additive_Interaction_of_the_Cannabinoid_Receptor_I.19.aspx
Peripheral cannabinoid CB1 receptors inhibit evoked responses of nociceptive neurones in vivo (abst–2008) http://www.sciencedirect.com/science/article/pii/S0014299908002719
Endocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesia (abst–2008) http://www.ncbi.nlm.nih.gov/pubmed/18485596?dopt=Abstract&holding=f1000,f1000m,isrctn
Endogenous cannabinoids induce fever through the activation of CB1 receptors (full–2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765314/?tool=pubmed
The effects of intracerebroventricular AM-251, a CB1-receptor antagonist, and ACEA, a CB1-receptor agonist, on penicillin-induced epileptiform activity in rats (full–2009) http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2009.02098.x/full
Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB(1) agonist ACEA in the pentylenetetrazole-induced seizure in mice (abst–2009) http://www.ncbi.nlm.nih.gov/pubmed/19223154
Involvement of nitric oxide in the gastroprotective effect of ACEA, a selective cannabinoid CB1 receptor agonist, on aspirin-induced gastric ulceration (abst–2009) http://www.ncbi.nlm.nih.gov/pubmed/19827302
Effect of arachidonyl-2′-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the protective action of the various antiepileptic drugs in the mouse maximal electroshock-induced seizure model (abst–2009) http://www.ncbi.nlm.nih.gov/pubmed/19751793
Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats (abst–2009) http://www.ncbi.nlm.nih.gov/pubmed/19150453


ACPA/ARACHIDONYLCYCLOPROPYLAMIDE
Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity (abst–2001) http://www.ncbi.nlm.nih.gov/pubmed/11828716
Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors (abst-2003) http://www.ncbi.nlm.nih.gov/pubmed/12921861
The preventive effect of cannabinoids on reperfusion-induced ischemia of mouse kidney (abst-2008) http://www.ncbi.nlm.nih.gov/pubmed/18571910
Effects of Cannabinoids on Caffeine Contractures in Slow and Fast Skeletal Muscle Fibers of the Frog (full-2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697372/?tool=pmcentrez


AJULEMIC ACID/AjA/IP-751/HU-239/CT-3
The Role of Cannabis and Cannabinoids in Pain Management (full–2002) http://www.humanhemphealth.ca/Russo-AAPM_chapter.pdf
Marijuana-Derived Compound Targets Pain, Inflammation (news–2002) http://www.sciencedaily.com/releases/2002/08/020822071026.htm
Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial (full–2003) http://jama.ama-assn.org/cgi/content/full/290/13/1757?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Ajulemic acid: A novel cannabinoid produces analgesia without a “high” (abst–2004) http://www.ncbi.nlm.nih.gov/pubmed/15240185?dopt=Abstract
Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (full-2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751505/?tool=pubmed
Marijuana-Derived Drug Suppresses Bladder Overactivity And Irritation In Animal Models (news-2005) http://www.sciencedaily.com/releases/2005/09/050906080225.htm
Cannabimimetic Properties of Ajulemic Acid (full–2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633725/?tool=pmcentrez
Marijuana-Derived Drug Suppresses Bladder Pain In Animal Models (news-2006) http://www.sciencedaily.com/releases/2006/05/060521103039.htm
Cannabimimetic Properties of Ajulemic Acid (full–2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633725/
In humans, ajulemic acid has a more favorable side-effect profile than THC for the treatment of chronic neuropathic pain (full-2007) http://www.cannabis-med.org/english/journal/en_2007_01_1.pdf
Letter: Preclinical assessment of abuse liability of ajulemic acid (letter–2007) http://www.cannabis-med.org/english/journal/en_2007_01_2.pdf
Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid (abst-2007) http://www.ncbi.nlm.nih.gov/pubmed/16927387
Effects of IP-751, ajulemic acid, on bladder overactivity induced by bladder irritation in rats (abst-2007) http://www.ncbi.nlm.nih.gov/pubmed/17656248
Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances (abst-2007) http://www.ncbi.nlm.nih.gov/pubmed/17868014
Cannabinoids in the management of difficult to treat pain (full–2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503660/?tool=pmcentrez
Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells (abst-2008) http://www.ncbi.nlm.nih.gov/pubmed/17786950
Ajulemic acid, a synthetic cannabinoid acid, induces an antiinflammatory profile of eicosanoids in human synovial cells (abst–2008) http://www.ncbi.nlm.nih.gov/pubmed/18840450
Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid (abst-2008) http://www.ncbi.nlm.nih.gov/pubmed/18040689
Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation (full–2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664885/?tool=pmcentrez
Cannabinoids as novel anti-inflammatory drugs (full-2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/?tool=pubmed
Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4 (full–2009) http://www.fasebj.org/cgi/content/full/23/5/1503?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=2400&resourcetype=HWCIT


AM-111/D-JNKI-1/XG-102
AM-111 (news–undated) http://www.aurismedical.com/p/therapies/am_111.php?lg=en
A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss (full–2003) http://www.jneurosci.org/content/23/24/8596.long
Cochlear implantation trauma and noise-induced hearing loss: Apoptosis and therapeutic strategies (full-2006) http://onlinelibrary.wiley.com/doi/10.1002/ar.a.20305/pdf
AM-111 reduces hearing loss in a guinea pig model of acute labyrinthitis (abst–2007) http://www.ncbi.nlm.nih.gov/pubmed/18322422
Intratympanic treatment of acute acoustic trauma with a cell-permeable JNK ligand: a prospective randomized phase I/II study (abst–2007) http://www.ncbi.nlm.nih.gov/pubmed/17712672
AM-111 protects against permanent hearing loss from impulse noise trauma (abst–2007) http://www.ncbi.nlm.nih.gov/pubmed/16839720
AM-111 prevents hearing loss from semicircular canal injury in otitis media (full–2009) http://onlinelibrary.wiley.com/doi/10.1002/lary.20759/pdf
Blocking pro-cell-death signal pathways to conserve hearing (abst–2009) http://www.ncbi.nlm.nih.gov/pubmed/19923808
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AM-251
Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors (full-2001) http://jpet.aspetjournals.org/content/299/3/951.full
Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats (full-2002) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573379/?tool=pmcentrez
CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full-2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573770/?tool=pmcentrez
Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery (full-2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573773/?tool=pmcentrez
Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN (full-2003) http://www.jleukbio.org/cgi/content/full/75/3/453?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT
Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2 Cannabinoid Receptors (full–2003) http://journals.lww.com/anesthesiology/Fulltext/2003/10000/Inhibition_of_Inflammatory_Hyperalgesia_by.31.aspx
Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats (full-2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575196/?tool=pmcentrez
Up-Regulation of Cyclooxygenase-2 Expression Is Involved in R(_)-Methanandamide-Induced Apoptotic Death of Human Neuroglioma Cells (full-2004) http://molpharm.aspetjournals.org/content/66/6/1643.full.pdf+html
Heterogeneity in the mechanisms of vasorelaxation to anandamide in resistance and conduit rat mesenteric arteries (full–2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574972/
The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis (full-2005) https://www.jstage.jst.go.jp/article/tjem/207/2/207_2_99/_pdf
Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus (abst–2005) http://www.sciencedirect.com/science/article/pii/S0028390805001668
Binding affinity and agonist activity of putative endogenous cannabinoids at the human neocortical CB1 receptor (abst-2005) http://www.ncbi.nlm.nih.gov/pubmed/15588725
Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy (full-2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808496/?tool=pmcentrez
AM 251 produces sustained reductions in food intake and body weight that are resistant to tolerance and conditioned taste aversion (full–2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615836/?tool=pmcentrez
Antinociceptive effect of cannabinoid agonist WIN 55,212–2 in rats with a spinal cord injury (full-2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez
EFFECT OF CANNABINOIDS ON TESTICULAR ISCHEMIA-REPERFUSION INJURY IN RAT (full–2006) http://journals.tums.ac.ir/upload_files/pdf/_/3279.pdf
Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor (full–2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1616976/
Inhibition of Salivary Secretion by Activation of Cannabinoid Receptors (full/forum repost-2006) http://www.420magazine.com/forums/am-251/142301-inhibition-salivary-secretion-activation-cannabinoid-receptors.html
Cannabinoid derivatives induce cell death in pancreatic MIA PaCa-2 cells via a receptor-independent mechanism (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/16500647
Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxib and their combinations in a model of neuropathic pain (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/16442133
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/16480822
Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full-2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez
CANNABINOID-INDUCED HYPERPHAGIA: CORRELATION WITH INHIBITION OF PROOPIOMELANOCORTIN NEURONS? (full–2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720321/?tool=pmcentrez
Cannabinoid action in the olfactory epithelium (full–2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1815290/?tool=pmcentrez
Ultra-low dose cannabinoid antagonist AM251 enhances cannabinoid anticonvulsant effects in the pentylenetetrazole-induced seizure in mice (abst-2007) http://www.ncbi.nlm.nih.gov/pubmed/17870135
The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors (abst–2007) http://www.sciencedirect.com/science/article/pii/S0014299907007935
Effect of Endocannabinoid System on the Neurogenic Function of Rat Corpus Cavernosum (abst–2007) http://rjms.iums.ac.ir/browse.php?a_code=A-10-1-760&sid=1&slc_lang=en
Cannabinoids Inhibit HIV-1 Gp120-Mediated Insults in Brain Microvascular Endothelial Cells (full-2008) http://www.jimmunol.org/cgi/content/full/181/9/6406?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT
Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells (full–2008) http://molpharm.aspetjournals.org/content/74/1/20.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT#content-block
Loss of cannabinoid receptor 1 accelerates intestinal tumor growth (full–2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561258/?tool=pubmed
Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats (full-2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697765/?tool=pmcentrez
Activating Parabrachial Cannabinoid CB1 Receptors Selectively Stimulates Feeding of Palatable Foods in Rats (full–2008) http://www.jneurosci.org/cgi/content/full/28/39/9702?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Feeding induced by cannabinoids is mediated independently of the melanocortin system (full-2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386290/?tool=pubmed
Acute effects of endocannabinoid anandamide and CB1 receptor antagonist, AM251 in the regulation of thyrotropin secretion (full–2008) http://joe.endocrinology-journals.org/content/199/2/235.long
High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells (abst-2008) http://www.ncbi.nlm.nih.gov/pubmed/18615640
Effect of biliary cirrhosis on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum: Role of nitric oxide pathway and endocannabinoid system (abst–2008) http://journals.tums.ac.ir/abs.aspx?culture_var=en&journal_id=9&org_id=59&manuscript_id=6272
Effect of anandamide in improving of the non-adrenergic non-cholinergic relaxation of the corpus cavernosum from diabetic rats (abst–2008) http://journals.tums.ac.ir/abs.aspx?org_id=59&culture_var=en&journal_id=9&issue_id=1415&manuscript_id=12280&segment=fa
Endocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesia (abst–2008) http://www.ncbi.nlm.nih.gov/pubmed/18485596?dopt=Abstract&holding=f1000,f1000m,isrctn
Peripheral cannabinoid CB1 receptors inhibit evoked responses of nociceptive neurones in vivo (abst–2008) http://www.sciencedirect.com/science/article/pii/S0014299908002719
Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice (full-2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697695/?tool=pubmed
Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid system (full–2009) http://stroke.ahajournals.org/content/40/6/2157.long
Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory (full–2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660732/?tool=pmcentrez
Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids (full–2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739820/?tool=pubmed
The effects of intracerebroventricular AM-251, a CB1-receptor antagonist, and ACEA, a CB1-receptor agonist, on penicillin-induced epileptiform activity in rats (full–2009) http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2009.02098.x/full
Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats (full-2009) http://www.if-pan.krakow.pl/pjp/pdf/2009/2_304.pdf
Processing cardiovascular information in the vlPAG during electro-acupuncture in rats: roles of endocannabinoids and GABA (full–2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692771/#!po=4.54545
Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats (abst–2009) http://www.ncbi.nlm.nih.gov/pubmed/19409856
Cannabinoids and neurodegenerative diseases (abst-2009) http://www.ncbi.nlm.nih.gov/pubmed/19839933
Endocannabinoids prevent lysosomal membrane destabilisation evoked by treatment with β-amyloid in cultured rat cortical neurons (forum repost/abst-2009) http://forum.grasscity.com/medical-marijuana-usage-applications/1029121-alzheimers-study.html#post14325992


AM-281
123I]AM281 single-photon emission computed tomography imaging of central cannabinoid CB1 receptors before and after Delta9-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in tourette patients (abst–2004) http://www.ncbi.nlm.nih.gov/pubmed/15110734
Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (full-2005) http://bja.oxfordjournals.org/content/94/5/563.full
Treatment of Tourette-syndrome with cannabinoids: results from clinical and neuroimaging studies (abst–2005) https://www.thieme-connect.com/ejournals/abstract/10.1055/s-2005-918789
The analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptors (abst–2005) http://www.sciencedirect.com/science/article/pii/S0014299905013178
Effects of AM281, a cannabinoid antagonist, on circulatory deterioration and cytokine production in an endotoxin shock model: comparison with norepinephrine (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/17072693
The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation (full–2009) http://www.fasebj.org/content/23/1/183.long


AM-404
Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172 (full–2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC423268/
Easing anxiety with anandamide (news–2004) http://www.rsc.org/chemistryworld/Issues/2004/July/anandamide.asp
Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala (full-2005) http://www.nature.com/npp/journal/v30/n3/full/1300535a.html
Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full – 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html
Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system (full-2005) http://www.jbc.org/content/280/36/31405.long
Anxiolytic-like properties of the anandamide transport inhibitor AM404 (full–2006) http://www.nature.com/npp/journal/v31/n12/full/1301061a.html
The Endogenous Cannabinoid Anandamide Produces δ-9-Tetrahydrocannabinol-Like Discriminative and Neurochemical Effects That Are Enhanced by Inhibition of Fatty Acid Amide Hydrolase but Not by Inhibition of Anandamide Transport (full-2007) http://jpet.aspetjournals.org/content/321/1/370.full
Δ9-Tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors (full-2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189998/?tool=pmcentrez
STUDIES OF ANANDAMIDE ACCUMULATION INHIBITORS IN CEREBELLAR GRANULE NEURONS (full–2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248273/
The acetaminophen-derived bioactive N-acylphenolamine AM404 inhibits NFAT by targeting nuclear regulatory events (abst–2007) http://www.ncbi.nlm.nih.gov/pubmed/17196940
Pharmacological enhancement of endocannabinoid signaling reduces the cholinergic toxicity of diisopropylfluorophosphate (full–2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659532/
Pro-drugs for indirect cannabinoids as therapeutic agents (abst–2008) http://www.ncbi.nlm.nih.gov/pubmed/18855592
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AM-630
Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN (full-2003) http://www.jleukbio.org/cgi/content/full/75/3/453?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT
Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2 Cannabinoid Receptors (full–2003) http://journals.lww.com/anesthesiology/Fulltext/2003/10000/Inhibition_of_Inflammatory_Hyperalgesia_by.31.aspx
Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors (abst-2004) http://www.ncbi.nlm.nih.gov/pubmed/15556131
Antinociceptive effect of cannabinoid agonist WIN 55,212–2 in rats with a spinal cord injury (full-2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez
Inhibition of Salivary Secretion by Activation of Cannabinoid Receptors (full/forum repost-2006) http://www.420magazine.com/forums/am-251/142301-inhibition-salivary-secretion-activation-cannabinoid-receptors.html
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/16480822
Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxib and their combinations in a model of neuropathic pain (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/16442133
The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors (abst–2007) http://www.sciencedirect.com/science/article/pii/S0014299907007935
Regulation of Bone Mass, Osteoclast Function, and Ovariectomy-Induced Bone Loss by the Type 2 Cannabinoid Receptor (full–2008) http://press.endocrine.org/doi/full/10.1210/en.2008-0150
Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells (full–2008) http://molpharm.aspetjournals.org/content/74/1/20.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT#content-block
Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis (full-2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688760/?tool=pubmed
Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats (abst–2009) http://www.ncbi.nlm.nih.gov/pubmed/19409856


AM-1172
Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172 (full–2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC423268/
New molecule may be basis for drugs that battle overeating and drug dependency (news–2004) http://archive.today.uci.edu/news/release_detail.asp?key=1155
Easing anxiety with anandamide (news–2004) http://www.rsc.org/chemistryworld/Issues/2004/July/anandamide.asp
Anandamide Compound Targets Brain’s ‘Bliss’ System (news–2005) http://alcoholism.about.com/od/cure/a/blnida050112.htm
STUDIES OF ANANDAMIDE ACCUMULATION INHIBITORS IN CEREBELLAR GRANULE NEURONS (full – 2007)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248273/


AM-1241
Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS (full-2003) http://www.pnas.org/content/100/18/10529.full
Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2 Cannabinoid Receptors (full–2003) http://journals.lww.com/anesthesiology/Fulltext/2003/10000/Inhibition_of_Inflammatory_Hyperalgesia_by.31.aspx
New Compound That Acts On Peripheral Receptors May Be Promising Treatment For Some Nerve Pain (news-2003) http://www.sciencedaily.com/releases/2003/08/030812073750.htm
CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids (full-2005) http://www.pnas.org/content/102/8/3093.full
Cannabinoid CB2 receptor agonist activity in the hindpaw incision model of postoperative pain (abst-2005) http://www.ncbi.nlm.nih.gov/pubmed/16316653
In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor? (full-2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013801/?tool=pubmed
AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis (abst-2006) http://www.ncbi.nlm.nih.gov/pubmed/16781706
The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset (full–2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819701/?tool=pmcentrez
Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice (full-2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/
Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats (full–2008) http://jpet.aspetjournals.org/content/327/2/584.full#content-block
The endocannabinoid system in amyotrophic lateral sclerosis (abst–2008) http://www.ncbi.nlm.nih.gov/pubmed/18781981
Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis (full-2009) http://onlinelibrary.wiley.com/doi/10.1002/ibd.20960/full


AM-1346
Synthetic Cannabinoid May Aid Fertility In Smokers (news–2006) http://www.medicalnewstoday.com/articles/58063.php
Marijuana-like Chemical Can Restore Sperm Function Lost to Tobacco Abuse (news-2006) http://www.rxpgnews.com/specialtopics/article_5093.shtml
Cannabis-based boost for smokers’ suffering sperm (news–2006) (may need registration) http://www.newscientist.com/article/dn10362-cannabisbased-boost-for-smokers-suffering-sperm.html
Effects of AM1346, a high-affinity CB1 receptor selective anandamide analog, on open-field behavior in rats (abst – 2007) http://www.ncbi.nlm.nih.gov/pubmed/17912052
Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog (full–2008) http://www.springerlink.com/content/n278340k6q47141k/fulltext.html
Scientist Discovers New Molecule to Treat Chronic Pain (news – 2008) http://www.physorg.com/news137778721.html


AM-1710
Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors (abst-2004) http://www.ncbi.nlm.nih.gov/pubmed/15556131
Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity (abst–2007) http://www.ncbi.nlm.nih.gov/pubmed/18038967


AM-2233
F200A substitution in the third transmembrane helix of human cannabinoid CB1 receptor converts AM2233 from receptor agonist to inverse agonist (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/16438957
Evaluation of the in vivo receptor occupancy for the behavioral effects of cannabinoids using a radiolabeled cannabinoid receptor agonist, R-[125/131I]AM2233 (abst–2006) http://www.ncbi.nlm.nih.gov/pubmed/16715483


AM-4054
Behavioral Profile of the Novel Cannabinoid Agonist AM4054 (thesis-2006) http://digitalcommons.uconn.edu/cgi/viewcontent.cgi?article=1016&context=srhonors_theses&sei-redir=1#search=%22am-4054%20%2Bcannabinoid%22
Effects of a Selective Cannabinoid Agonist and Antagonist on Body Temperature in Rats (abst-2007) http://www.fasebj.org/cgi/content/meeting_abstract/21/5/A409?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT


AM-4113
Effects of a Selective Cannabinoid Agonist and Antagonist on Body Temperature in Rats (abst–2007) http://www.fasebj.org/cgi/content/meeting_abstract/21/5/A409?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT
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