W

+ Studies in 2000-2009 List
* Studies in Pre-2000 List

WILSON’S DISEASE (See 2000–2009 List)
WITHDRAWAL SYNDROME*+
WOUNDS/INJURIES +


WITHDRAWAL SYNDROME
Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada) (full-2010) http://www.hc-sc.gc.ca/dhp-mps/marihuana/med/infoprof-eng.php
Rimonabant-induced Delta9-tetrahydrocannabinol withdrawal in rhesus monkeys: discriminative stimulus effects and other withdrawal signs (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912042/pdf/zpt347.pdf
Anxiety-like effects of SR141716-precipitated delta9-tetrahydrocannabinol withdrawal in mice in the elevated plus-maze (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923489/
The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188916/pdf/bph0164-0655.pdf
Antagonist-elicited cannabis withdrawal in humans (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717344/
A genetic perspective on the proposed inclusion of cannabis withdrawal in DSM-5 (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733446/
A proof-of-concept randomized controlled study of gabapentin: effects on cannabis use, withdrawal and executive function deficits in cannabis-dependent adults (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358737/
Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report (abst-2012) http://onlinelibrary.wiley.com/doi/10.1111/jcpt.12018/abstract
Electroacupuncture inhibits CB1 upregulation induced by ethanol withdrawal in mice (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/22613131
Anticonvulsant Drug Helps Marijuana Smokers Kick the Habit (news-2012) http://www.sciencedaily.com/releases/2012/04/120424095651.htm
Nabilone decreases marijuana withdrawal and a laboratory measure of marijuana relapse (full-2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682150/
Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Anti-Withdrawal Effects in Morphine-Dependent Mice (full-2013) http://www.ncbi.nlm.nih.gov/pubmed/23303065
Suspected Dronabinol Withdrawal in an Elderly Cannabis-Naive Medically Ill Patient (letter-2013) http://ajp.psychiatryonline.org/article.aspx?articleid=1700628
Effects of acute detoxification of the herbal blend ‘Spice Gold’ on dopamine D2/3 receptor availability: A [18F]fallypride PET study. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23452563
Palmitoylethanolamide: From endogenous cannabimimetic substance to innovative medicine for the treatment of cannabis dependence. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23896215
The Synthetic Cannabinoid Withdrawal Syndrome (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23609214
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Plasma Cannabinoid Concentrations During Dronabinol Pharmacotherapy for Cannabis Dependence (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24067260
Cannabis withdrawal syndrome: An important diagnostic consideration in adolescents presenting with disordered eating (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24281745
Cannabis withdrawal in chronic, frequent cannabis smokers during sustained abstinence within a closed residential environment (abst–2013) http://onlinelibrary.wiley.com/doi/10.1111/j.1521-0391.2013.12088.x/abstract
4 Myths About Marijuana Addiction (news–2013) http://www.leafscience.com/2013/11/28/4-myths-marijuana-addiction/
‘Legal high’ users turn to real thing (news–2013) http://www.odt.co.nz/news/national/266889/legal-high-users-turn-real-thing
Baclofen in the management of cannabis dependence syndrome (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896138/
The effect of AM281, a cannabinoid antagonist, on memory performance during spontaneous morphine withdrawal in mice (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895301/
Nabiximols as an Agonist Replacement Therapy During Cannabis Withdrawal: A Randomized Clinical Trial (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24430917
Evaluation of sex differences in cannabinoid dependence (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24582909
Changes in cigarette and alcohol use during cannabis abstinence (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24613633
Cannabis withdrawal in chronic, frequent cannabis smokers during sustained abstinence within a closed residential environment (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24724880
Cannabis Withdrawal in Patients With and Without Opioid Dependence (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24745656
A new method of cannabis ingestion: The dangers of dabs? (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24930049
Effects of opioids and cannabinoids during chronic morphine treatment in rhesus monkeys (abst-2014) http://www.fasebj.org/content/28/1_Supplement/658.3.abstract?sid=467bb529-0ecc-4ddc-af27-3f56f520a102
The FAAH inhibitor PF-04457845 has THC-like rewarding and reinstatement effects in squirrel monkeys and increases dopamine levels in the nucleus accumbens shell in rats (abst-2014) http://www.fasebj.org/content/28/1_Supplement/838.6.abstract?sid=db987fd0-3ef0-4796-aff6-4103f0c84daf
Comparative effects of pulmonary and parenteral Δ9-tetrahydrocannabinol exposure on extinction of opiate-induced conditioned aversion in rats (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25395060
Potential use of Magnolia officinalis bark polyphenols in the treatment of cannabis dependence (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25459131
The endocannabinoid system regulates synaptic transmission in nucleus accumbens by increasing DAGL-α expression following short-term morphine withdrawal (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25296881
Early Withdrawal Effects in a Heavy Cannabis Smoker During Hemodialysis (abst-2014) http://www.biologicalpsychiatryjournal.com/article/S0006-3223%2814%2900610-6/abstract
Synthetic cannabinoid withdrawal: A new demand on detoxification services (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25588420
Cannabis Withdrawal Among Detained Adolescents: Exploring the Impact of Nicotine
and Race (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331066/
Cannabis and psychopathology: The meandering journey of the last decade (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462782/
Synthetic cannabinoid withdrawal: A new demand on detoxification services (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25588420
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Cannabinoid withdrawal in mice: inverse agonist vs neutral antagonist (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25772338
Cannabinoid Replacement Therapy (CRT): Nabiximols (Sativex) as a novel treatment for cannabis withdrawal (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25777582
Withdrawal Seizures Seen In the Setting of Synthetic Cannabinoid Abuse (abst–2015) http://www.ajemjournal.com/article/S0735-6757%2815%2900169-2/abstract
Cannabis withdrawal and sleep: A systematic review of human studies (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25893849
The effects of dronabinol during detoxification and the initiation of treatment with extended release naltrexone. (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26187456
The impact of gonadal hormones on cannabinoid dependence (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26237318
Catatonia and Cannabis Withdrawal: a case report (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26247767
Withdrawal drug could help cannabis addicts kick the habit (news – 2015) https://www.newscientist.com/article/mg22630204-500-withdrawal-drug-could-help-cannabis-addicts-kick-the-habit/


WOUNDS/INJURIES 
Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878341/?toolmcentrez
Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926165/
Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936832/
The cannabinoid receptor type 2 is time-dependently expressed during skeletal muscle wound healing in rats (abst-2010) http://www.ncbi.nlm.nih.gov/pubmed/20535492
Involvement of the endocannabinoid system in periodontal healing (abst-2010) http://www.ncbi.nlm.nih.gov/pubmed/20233580
Expression of cannabinoid receptor I during mice skin incised wound healing course (abst-2010) http://www.ncbi.nlm.nih.gov/pubmed/20967946
Compound boosts marijuana-like chemical in the body to relieve pain at injury site (news-2010) http://www.eurekalert.org/pub_releases/2010-09/uoc–cbm092010.php
Study: Smoking pot may ease chronic pain (news-2010) http://www.cnn.com/2010/HEALTH/08/30/health.pot.reduce.pain/
2-Arachidonoylglycerol (2-AG) Induces Corneal Epithelial Cell Migration via Cannabinoid CB1 Receptors (abst-2011) http://abstracts.iovs.org/cgi/content/abstract/52/6/1995?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT
Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607947/
Cannabinoid receptor type 2 is time-dependently expressed during skin wound healing in mice (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/22814434
Differential migratory properties of monocytes isolated from human subjects naïve and non-naïve to Cannabis (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/22492174
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The Dual Effect of Cannabinoid Receptor-1 Deficiency on the Murine Postoperative Ileus (full-2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067427
A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ. (full – 2013) https/peerj.com/articles/40/
Involvement of nitric oxide through endocannabinoids release in microglia activation during the course of CNS regeneration in the medicinal leech (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/23355252
Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases? (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24823963
Cannabinoid Receptor Type 1 Antagonist, AM251, Attenuates Mechanical Allodynia and Thermal Hyperalgesia after Burn Injury (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25188001
Interaction of a Cannabinoid-2 Agonist With Tramadol on Nociceptive Thresholds and Immune Responses in a Rat Model of Incisional Pain (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25370921
Beneficial effects of cannabinoid receptor type 2 (CB2R) in injured skeletal muscle post contusion (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25588471
Honokiol Decreases Intra-Abdominal Adhesion Formation in a Rat Model (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25632973
CB2R orchestrates fibrogenesis through regulation of inflammatory response during the repair of skeletal muscle contusion (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466920/
Beneficial effects of cannabinoid receptor type 2 (CB2R) in injured skeletal muscle postcontusion (full-2015) http://www.hh.um.es/pdf/Vol_30/30_6/Yu-30-737-749-2015.pdf
Cannabidiol, a Major Non-Psychotrophic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25801536
The monoacylglycerol lipase inhibitor JZL184 decreases inflammatory response in skeletal muscle contusion in rats (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25912803
Endocannabinoids regulate the activity of astrocytic hemichannels and the microglial response against an injury: In vivo studies (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25917763
Study: Cannabis helps to heal bone fractures (news-2015) http://www.upi.com/Health_News/2015/07/16/Study-Cannabis-helps-to-heal-bonefractures/9431437083214/
No bones about it: Cannabis may be used to treat fractures (news-2015) http://medicalxpress.com/news/2015-07-bones-cannabis-fractures.html
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