O

+ Studies in 2000-2009 List
* Studies in Pre-2000 List

OBESITY*+
OBSESSIVE COMPULSIVE DISORDER/OCD +
OLDER ADULT CANNABIS USERS +
OMEGA-3/CB1 CONNECTION*+ (Without Omega-3, New CB1 Receptors are Made Imperfectly. See Also NUTRITION-HEMP SEED OIL, CBR-CB1 RECEPTORS)
OMEGA-6/ENDOCANNABINOID CONNECTION (Endocannabinoids are made from Omega-6)
OMEGA-9
ORGAN TRANSPLANTS*+
OSTEOPOROSIS/BONES and CARTILAGE +
OVARIAN CYSTS +
OVERDOSES on CANNABINOIDS*+ (See Also CANNABINOID HYPEREMESIS SYNDROME, SPICE)
OVERVIEWS*+


OBESITY
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice (full-2010) http://www.jneurosci.org/content/30/18/6273.long
Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full-2010) http://www.lipidworld.com/content/9/1/43
Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype (full-2010) http://ajpgi.physiology.org/content/299/1/G63.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c
Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution (full-2010) http://www.eje-online.org/content/163/3/407.full
The endocannabinoid system links gut microbiota to adipogenesis (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925525/
CD36 gene deletion decreases oleoylethanolamide levels in small intestine of freefeeding mice (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846762/?toolubmed
A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013130/?toolubmed
The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure (full-2010) http://onlinelibrary.wiley.com/doi/10.1038/oby.2008.509/full
Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868848/?toolubmed
Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways. (full – 2010) http://diabetes.diabetesjournals.org/content/59/11/2826.full.pdf+html
The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food reinforced behavior. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522179/
Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912197/
A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia. (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055343/?toolubmed
top
Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes? (full – 2010) http://www.jci.org/articles/view/44099?search%5Babstract_text%5D=&search%5Barticle_text%5D=cannabinoid&search%5Bauthors_text%5D=&search%5Bfpage%5D=&search%5Btitle_text%5D=&search%5Bvolume%5D=
Modulation of Adipocyte Biology by Δ9-Tetrahydrocannabinol (full – 2010) http://onlinelibrary.wiley.com/doi/10.1038/oby.2010.100/full
Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis (full – 2010) http://www.nature.com/npp/journal/v35/n9/full/npp201058a.html
Perspectives of CB1 Antagonist in Treatment of Obesity: Experience of RIO-Asia (full – 2010) http://www.hindawi.com/journals/jobes/2011/957268/
A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990160/
A one-year study to assess the safety and efficacy of the CB1R inverse agonist taranabant in overweight and obese patients with type 2 diabetes (full-2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1463-1326.2009.01188.x/full
Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20936991
A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: low-dose study (abst – 2010) http://www.nature.com/ijo/journal/v34/n5/abs/ijo201021a.html
Analysis of gene expression pattern reveals potential targets of dietary oleoylethanolamide in reducing body fat gain in C3H mice. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/19954948
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20851297
Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20013888
Cannabis Use and Obesity and Young Adults (abst – 2010) http://informahealthcare.com/doi/abs/10.3109/00952990.2010.500438
The endocannabinoid system modulates the valence of the emotion associated to food ingestion (abst – 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1369-1600.2010.00271.x/abstract
Endocannabinoid signaling and energy metabolism: a target for dietary intervention (abst-2011) http://www.ncbi.nlm.nih.gov/pubmed/21470818
Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function (full – 2011) http://www.nutritionandmetabolism.com/content/8/1/93
Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048484/?toolubmed
Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice (full – 2011) http://www.nutritionandmetabolism.com/content/8/1/51
Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fat-fed mice (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111743/?toolubmed
Roles of G1359A polymorphism of the cannabinoid receptor gene (CNR1) on weight loss and adipocytokines after a hypocaloric diet (full – 2011) http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112011000200012&lng=en&nrm=iso
top
The activity of the endocannabinoid metabolising enzyme fatty acid amide hydrolase in subcutaneous adipocytes correlates with BMI in metabolically healthy humans (full-2011) http://www.lipidworld.com/content/10/1/129
Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084524/?toolubmed
The association of the rs1049353 polymorphism of the CNR1 gene with hypoadiponectinemia. (full – 2011) http://www.rjme.ro/RJME/resources/files/520311791795.pdf
The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant’s antiobesity effects in mice (full – 2011) http://onlinelibrary.wiley.com/doi/10.1038/oby.2011.250/full
Gadolinium-HU-308-incorporated micelles. (full – 2011) http://www.ncbi.nlm.nih.gov/books/NBK54067/pdf/CB2R-Gd-Micelles.pdf
Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise (full – 2011) http://www.lipidworld.com/content/10/1/194
385 C/A polymorphism of the fatty acid amide hydrolase gene is associated with metabolic syndrome in the Chinese Han population. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258756/
Greasing the wheels of managing overweight and obesity with omega-3 fatty acids. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210336/
Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303536/
Obesity and Cannabis Use: Results From 2 Representative National Surveys (full – 2011) http://aje.oxfordjournals.org/content/early/2011/08/24/aje.kwr200.full
Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038245/
The neutral cannabinoid CB₁ receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023913/
Effects of Chronic Oral Rimonabant Administration on Energy Budgets of Diet-Induced Obese C57BL/6 Mice. (full – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22173576
Sweet taste and (AAT)12 repeat in the cannabinoid receptor gene in obese females (letter-2011) https://www.jstage.jst.go.jp/article/endocrj/58/4/58_K11E-093/_pdf
The role of central CB2 cannabinoid receptors on food intake in neonatal chicks. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21927979
Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21326208
Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst – 2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm
Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women? (abst-2011) http://www.ncbi.nlm.nih.gov/pubmed/20838400
A Summary of Endocannabinoids and Obesity (news-2011) http://evolutionarypsychiatry.blogspot.com/2011/04/summary-of-endocannabinoids-and-obesity.html
top
Frequency Of Marijuana Use Associated With Lower Prevalence Of Obesity, Study Says (news-2011) http://www.norml.org/index.cfm?Group_ID=8670
Smoking marijuana not linked to obesity: study (news-2011) http://www.reuters.com/article/2011/09/09/us-marijuana-obesity-idUSTRE7886TT20110909
Body’s natural marijuana-like chemicals make fatty foods hard to resist (news-2011) http://www.eurekalert.org/pub_releases/2011-07/uoc–bnm063011.php
To Be or Not To Be-Obese (full-2012) http://endo.endojournals.org/content/152/10/3592.long
The L-α-lysophosphatidylinositol/GPR55 system and its potential role in human obesity (full-2012) http://diabetes.diabetesjournals.org/content/61/2/281.long
Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. (full – 2012) http://www.nutritionandmetabolism.com/content/pdf/1743-7075-8-93.pdf
Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. (full – 2012) http://www.pnas.org/content/109/37/14966.long
Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity. (full – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22829723?dopt=Abstract
Cannabinoid Receptor 1 (CNR1) 4895 C/T Genetic Polymorphism was Associated with Obesity in Japanese Men. (full – 2012) https://www.jstage.jst.go.jp/article/jat/19/8/19_12732/_pdf
Relationships between glucose, energy intake and dietary composition in obese adults with type 2 diabetes receiving the cannabinoid 1 (CB1) receptor antagonist, rimonabant (full – 2012) http://www.nutritionj.com/content/11/1/50
Excess of the endocannabinoid anandamide during lactation induces overweight, fat accumulation and insulin resistance in adult mice (full – 2012) http://www.dmsjournal.com/content/4/1/35
Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences. (full – 2012) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038609
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/
Over-Expression of Monoacylglycerol Lipase (MGL) in Small Intestine Alters Endocannabinoid Levels and Whole Body Energy Balance, Resulting in Obesity. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429419/
Type 2 Diabetes Associated Changes in the Plasma Non-Esterified Fatty Acids, Oxylipins and Endocannabinoids (full – 2012) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0048852
Endocannabinoids measurement in human saliva as potential biomarker of obesity. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409167/?toolubmed
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription (full-2012) http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02175.x/full
Gut microbiota and the development of obesity (full-2012) http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112012000500007&lng=en&nrm=iso&tlng=en
top
2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism (full-2012) http://ac.els-cdn.com/S1550413112000526/1-s2.0-S1550413112000526-main.pdf?_tid=186a88ec-7369-11e3-8095-00000aab0f02&acdnat=1388638277_735058a6f79f41a9199132aed604fdab
CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342253/
Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice (full-2012) http://press.endocrine.org/doi/full/10.1210/en.2012-1405
Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548985/
Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study (full-2012) http://press.endocrine.org/doi/full/10.1210/jc.2011-3018
Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE) (full-2012) http://fampra.oxfordjournals.org/content/29/5/521.full
Cannabinoid Type 1 Receptor Gene Polymorphism and Macronutrient Intake (full-2012) http://www.karger.com/Article/FullText/343563
The thrifty lipids: endocannabinoids and the neural control of energy conservation (full-2012) http://www.ncbi.nlm.nih.gov/pubmed/22622030
Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621143/
The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21981246
Cannabinoid signalling regulates inflammation and energy balance: The importance of the brain-gut axis. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22269477
Diet-dependent modulation of hippocampal expression of endocannabinoid signalingrelated proteins in cannabinoid antagonist-treated obese rats. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23033907
Cannabis exposure associated with weight reduction and β-cell protection in an obese rat model. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22421529
Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-inudced obese mice. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22473329
Overexpression of cannabinoid CB2 receptor in the brain induces hyperglycaemia and a lean phenotype in adult mice. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22487302
Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22543671
Stimulation of acumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22728691
Associations of variants of CNR1 with obesity and obesity-related traits in Chinese women. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22244745
Photoperiodic Changes in Endocannabinoid Levels and Energetic Responses to Altered Signalling at CB1 Receptors in Siberian Hamsters (abst – 2012) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2826.2012.02312.x/abstract
The role of the endocannabinoid system in eating disorders: pharmacological implications (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/22785439
top
The potential use of cannabidiol in the therapy of metabolic syndrome (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22430005
GPR119 as a fat sensor. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22560300 Role of G1359A polymorphism of the cannabinoid receptor gene on weight loss and adipocytokines levels after two different hypocaloric diets. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21543209
Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21844878
The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22943701
Childhood Obesity and the Role of Dopamine D2 Receptor and Cannabinoid Receptor-1 Gene Polymorphisms. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23057570
New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22674489
Fatty acid flux and oxidation are increased by rimonabant in obese women. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22445512
‘Cannabis’ receptor discovery may help understanding of obesity and pain (news – 2012) http://phys.org/news/2012-08-cannabis-receptor-discovery-obesity-pain.html
How marijuana could help cure obesity-related diseases (news-2012) http://news.yahoo.com/marijuana-could-help-cure-obesity-related-diseases-175900182.html
Cannabis can help treat obesity (news – 2012) http://in.news.yahoo.com/cannabis-help-treat-obesity-121931025.html
Marijuana Slims? Why Pot Smokers Are Less Obese (news-2012) http://healthland.time.com/2011/09/08/marijuana-slims-pot-smoking-linked-to-lower-bodyweight/#ixzz21IEZq1Lg
Fight obesity… with marijuana? (news-2012) http://theweek.com/article/index/218940/fight-obesity-with-marijuana
New Drug Could Help Maintain Long-Term Weight Loss (news-2012) http://www.sciencedaily.com/releases/2012/07/120726122116.htm
Dietary Linoleic Acid Elevates the Endocannabinoids 2-AG and Anandamide and Promotes Weight Gain in Mice Fed a Low Fat Diet (full-2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889814/
The impact of marijuana use on glucose, insulin, and insulin resistance among US adults (full-2013) http://www.amjmed.com/article/S0002-9343%2813%2900200-3/fulltext
The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity (full-2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671751/
Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese zucker rats (full-2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063449
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men (full-2013) http://www.lipidworld.com/content/12/1/78
Alterations to Melanocortinergic, GABAergic and Cannabinoid Neurotransmission Associated with Olanzapine-Induced Weight Gain (full – 2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033548
Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons (full-2013) http://www.pnas.org/content/110/24/E2229.full
Food for thought: hormonal, experiential, and neural influences on feeding and obesity (full-2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818543/
top
Hypothalamic 2-Arachidonoylglycerol Regulates Multistage Process of High-Fat Diet Preferences (full – 2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038609
Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693401/
Orexin neurons use endocannabinoids to break obesity-induced inhibition (full–2013) http://www.pnas.org/content/110/24/9625.full
Effect of high fat-diet and obesity on gastrointestinal motility (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890396/
Insulin induces long-term depression of VTA dopamine neurons via endocannabinoids (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072656/
Cannabinoids, eating behaviour, and energy homeostasis (full–2013) http://onlinelibrary.wiley.com/doi/10.1002/dta.1594/full
Reduced Food Intake is the Major Contributor to the Protective Effect of Rimonabant on Islet in Established Obesity-Associated Type 2 Diabetes (full–2013) http://www.eymj.org/DOIx.php?id=10.3349/ymj.2013.54.5.1127
Developmental Role for Endocannabinoid Signaling in Regulating Glucose Metabolism and Growth (full–2013) http://diabetes.diabetesjournals.org/content/62/7/2359.full?sid=2f5bda2b-a9c7-432a-9588-80c99189164d
Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839776/
Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines (full – 2013) http://eurheartj.oxfordjournals.org/content/34/27/2063.long
Fatty Acid Modulation of the Endocannabinoid System and the Effect on Food Intake and Metabolism (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677644/
Effect of Nelumbo nucifera Petal Extracts on Lipase, Adipogenesis, Adipolysis, and Central Receptors of Obesity (full–2013) http://www.hindawi.com/journals/ecam/2013/145925/
The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome (full–2013) http://www.cell.com/cell-reports/fulltext/S2211-1247%2813%2900507-X
A potential role for GPR55 in gastrointestinal functions (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660623/
Genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) and their influence on anthropometric parameters and metabolic parameters under a high monounsaturated vs. high polyunsaturated fat hypocaloric diets (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23337343
Cannabis and Δ(9)-tetrahydrocannabinol (THC) for weight loss? (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23410498
Endocannabinoids and obesity. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23374723
Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23434135
Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23466458
The endocannabinoid system in obesity (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23596738
Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23620336
top
Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1α pathway. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23747418
Polymorphism rs3123554 in CNR2 reveals gender-specific effects on body weight and affects loss of body weight and cerebral insulin action. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23839870
Analysis of the “endocannabinoidome” in peripheral tissues of obese Zucker rats. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23830028
The Role of the Endocannabinoid System in Eating Disorders: Neurochemical and Behavioural Preclinical Evidence. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23829365
Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23932644
Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24008071
High fat diet and body weight have different effects on cannabinoid CB1 receptor expression in rat nodose ganglia. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24145047
Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in high-fat fed mice. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23901038
Role of Genetic Variation in the Cannabinoid Receptor Gene (CNR1) (G1359A Polymorphism) on Weight Loss and Cardiovascular Risk Factors After Liraglutide Treatment in Obese Patients With Diabetes Mellitus Type 2. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24322329
Regulation of GPR55 in rat white adipose tissue and serum LPI by nutritional status, gestation, gender and pituitary factors. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24378736
The regulation of food intake by the gut-brain axis: implications for obesity (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/22710925
Concurrent pharmacological modification of cannabinoid-1 and glucagon-like peptide-1 receptor activity affects feeding behavior and body weight in rats fed a free-choice, highcarbohydrate diet. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24370558
Effects of C358A polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) on weight loss, adipocytokines levels, and insulin resistance after a high polyunsaturated fat diet in obese patients. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24445122
Key Shift in Brain That Creates Drive to Overeat Identified (news – 2013) http://www.sciencedaily.com/releases/2013/04/130429154214.htm
Regular Marijuana Use is Associated With Favorable Indices to Diabetic Control, Say Investigators (news – 2013) http://www.news-medical.net/news/20130515/Regular-marijuana-use-is-associated-with-favorableindices-related-to-diabetic-control-say-investigators.aspx
Marijuana Users Have Better Blood Sugar Control (news – 2013) http://www.sciencedaily.com/releases/2013/05/130515085208.htm
Study: Why Pot Smokers Are Skinnier (news – 2013) http://www.theatlantic.com/health/archive/2013/05/study-why-pot-smokers-are-skinnier/275846/
Cannabis linked to prevention of diabetes (news – 2013) http://www.independent.co.uk/life-style/health-and-families/health-news/cannabis-linked-to-prevention-ofdiabetes-8616314.html
Study: Marijuana Smokers Are Thinner And Healthier Than Non-Users (news – 2013) http://www.opposingviews.com/i/society/study-marijuana-smokers-are-thinner-and-healthier-non-users
Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882055/
top
Oleoylethanolamide: a novel potential pharmacological alternative to cannabinoid antagonists for the control of appetite (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996326/
Vascular targets for cannabinoids: animal and human studies. (full – 2014) http://onlinelibrary.wiley.com/doi/10.1111/bph.12560/full
Long-term changes in the ghrelin-CB1R axis associated with the maintenance of lower body weight after sleeve gastrectomy (full – 2014) http://www.nature.com/nutd/journal/v4/n7/full/nutd201424a.html
A diet containing a nonfat dry milk matrix significantly alters systemic oxylipins and the endocannabinoid 2-arachidonoylglycerol (2-AG) in diet-induced obese mice. (full – 2014) http://www.nutritionandmetabolism.com/content/11/1/24
Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895006/
The Endocannabinoid System – Back to the Scene of Cardiometabolic Risk Factors Control? (full – 2014) https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1375653
The effects of obesity, diabetes and metabolic syndrome on the hydrolytic enzymes of the endocannabinoid system in animal and human adipocytes. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995979/
Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects. (full – 2014) http://onlinelibrary.wiley.com/doi/10.1002/oby.20728/full
Endocannabinoid Receptors Gene Expression in Morbidly Obese Women with Nonalcoholic Fatty Liver Disease (full – 2014) http://www.hindawi.com/journals/bmri/2014/502542/
Dietary Non-Esterified Oleic Acid Decreases the Jejunal Levels of Anorectic NAcylethanolamines (full – 2014) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100365
CB1 blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/22828945
Glucose metabolism: Focus on gut microbiota, the endocannabinoid system and beyond. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24631413
Endocannabinoids and energy homeostasis: An update. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24752980
Mitochondria: A Possible Nexus for the Regulation of Energy Homeostasis by the Endocannabinoid System? (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24801388
The endocannabinoid system and appetite: relevance for food reward. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24933167
GPR55: From orphan to metabolic regulator? (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24972076
Haloperidol and rimonabant increase delay discounting in rats fed high-fat and standardchow diets. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25000488
Antipsychotic induced weight gain: genetics, epigenetics, and biomarkers reviewed (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25138234
Genetic Sensitivity to the Bitter Taste of 6-n-Propylthiouracil (PROP) and Its Association with Physiological Mechanisms Controlling Body Mass Index (BMI) (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25166026
Endocannabinoid signaling and food addiction (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25173635
Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25093427
top
Gut microbiota and obesity: Role in aetiology and potential therapeutic target (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25194177
CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25352999
Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25413674
Cannabinoid type 1 (CB1) receptors on Sim1-expressing neurons regulate energy expenditure in male mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25456065
Neural Effects of Cannabinoid CB1 Neutral Antagonist Tetrahydrocannabivarin (THCv) on Food Reward and Aversion in Healthy Volunteers (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25542687
The role of gut hormones in appetite regulation (review) (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25532952
Cannabis use in relation to obesity and insulin resistance in the inuit population (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25557382
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full-2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (DIO) via GIP secretion from enteroendocrine K-cells in response to fat ingestion (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25628425
Two non-psychoactive cannabinoids reduce intra-cellular lipid levels and inhibit hepatosteatosis (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25595882
Anandamide is involved in appetite-related amygdala hyperactivations in schizophrenia patients treated with olanzapine: a functional magnetic resonance imaging study (1st page – 2015) http://journals.lww.com/psychopharmacology/Citation/2015/02000/Anandamide_Is_Involved_in_Appetite_Related.14.aspx
Marijuana Could Be the Answer to Fighting These 3 Diseases (news-2015) (may require free registration) http://www.fool.com/investing/general/2015/01/10/marijuana-could-be-the-answer-to-fighting-these-3.aspx
New study links marijuana use and low body weight among Nunavik Inuit (news-2015) http://www.nunatsiaqonline.ca/stories/article/65674new_study_links_marijuana_use_and_low_body_weight_among_inuit/
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full-2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (DIO) via GIP secretion from enteroendocrine K-cells in response to fat ingestion (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25628425
Two non-psychoactive cannabinoids reduce intra-cellular lipid levels and inhibit hepatosteatosis (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25595882
Anandamide is involved in appetite-related amygdala hyperactivations in schizophrenia patients treated with olanzapine: a functional magnetic resonance imaging study (1st page-2015) http://journals.lww.com/psychopharmacology/Citation/2015/02000/Anandamide_Is_Involved_in_Appetite_Related.14.aspx
Marijuana Could Be the Answer to Fighting These 3 Diseases (news-2015) (may require free registration) http://www.fool.com/investing/general/2015/01/10/marijuana-could-be-the-answer-to-fighting-these-3.aspx
top
New study links marijuana use and low body weight among Nunavik Inuit (news-2015) http://www.nunatsiaqonline.ca/stories/article/65674new_study_links_marijuana_use_and_low_body_weight_among_inuit/
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full-2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
Fatty Acid-Binding Protein 4 (FABP4): Pathophysiological Insights and Potent Clinical Biomarker of Metabolic and Cardiovascular Diseases (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315049/
Global deletion of monoacylglycerol lipase in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity (full-2015) http://www.jlr.org/content/early/2015/04/04/jlr.M058586.long
Leptin Levels Are Negatively Correlated with 2-Arachidonoylglycerol in the Cerebrospinal Fluid of Patients with Osteoarthritis (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383333/
Fat Diet-Induced Insulin Resistance Does Not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets (full-2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123558
Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423197/
Dietary Triacylglycerols with Palmitic Acid in the sn-2 Position Modulate Levels of NAcylethanolamides in Rat Tissues (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361611/
A cannabinoid receptor agonist N-arachidonoyl dopamine inhibits adipocyte differentiation in human mesenchymal stem cells (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428713/
The endocannabinoid anandamide during lactation increases body fat content and CB1 receptor levels in mice adipose tissue (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491858/
Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota (full-2015)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382707/
Anandamide is involved in appetite-related amygdala hyperactivations in schizophrenia patients treated with olanzapine: a functional magnetic resonance imaging study (1st page-2015) http://journals.lww.com/psychopharmacology/Citation/2015/02000/Anandamide_Is_Involved_in_Appetite
_Related.14.aspx
Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (DIO) via GIP secretion from enteroendocrine K-cells in response to fat ingestion (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25628425
Two non-psychoactive cannabinoids reduce intra-cellular lipid levels and inhibit hepatosteatosis (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25595882
Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25728242
Effects of a High-Protein/Low-Carbohydrate versus a Standard Hypocaloric Diet on Weight and Cardiovascular Risk Factors during 9 Months: Role of a Genetic Variation in the Cannabinoid Receptor Gene (CNR1) (G1359A Polymorphism) (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25766592
top
Association of G1359A polymorphism of the cannabinoid receptor gene (CNR1) with macronutrient intakes in obese females (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25664923
Polymorphism G1359A of the cannabinoid receptor gene (CNR1): allelic frequencies and influence on cardiovascular risk factors in a multicentre study of Castilla-Leon (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25682784
Analysis of FABP4 expression pattern in rump fat deposition and metabolism of Altay sheep (abst-2015)  http://www.ncbi.nlm.nih.gov/pubmed/25665644
Chronic administration with AM251 improves albuminuria and renal tubular structure in obese rats (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25804605
Association between paracetamol use in infancy or childhood with body mass index (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25864407
Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoylglycerol and arachidonoyl-ethanolamide, and their metabolites. (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25877930
Endocannabinoid system activation may be associated with insulin resistance in women with polycystic ovary syndrome (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25935491
Epigenetic and Proteomic Expression Changes Promoted by Eating Addictive-like Behavior (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25944409
Cigarette smoking may modify the association between cannabis use and adiposity in males (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/26026899
Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signalling Deficiency (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/26081302
A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/26161824
Strain and sex differences in puberty onset and the effects of THC administration on weight gain and brain volumes (abst-2015) http://www.sciencedirect.com/science/article/pii/S0306452215006387
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/26219414
Marijuana Could Be the Answer to Fighting These 3 Diseases (news-2015) (may require free registration) http://www.fool.com/investing/general/2015/01/10/marijuana-could-be-the-answer-to-fighting-these-3.aspx
New study links marijuana use and low body weight among Nunavik Inuit (news-2015) http://www.nunatsiaqonline.ca/stories/article/65674new_study_links_marijuana_use_and_low_body_weight_among_inuit/
Schizophrenia and weight gain: A new explanation? (news-2015) http://www.alphagalileo.org/ViewItem.aspx?ItemId=149445&CultureCode=en
Cannabinoids may be responsible for weight gain associated with schizophrenia (news-2015) http://medicalxpress.com/news/2015-02-cannabinoids-responsible-weight-gain-schizophrenia.html
Nunavik Inuit health study from 2004 continues to churn out info (news-2015) http://www.nunatsiaqonline.ca/stories/article/65674nunavik_inuit_health_study_from_2004_continues_to_churn_out_info/
top


OBSESSIVE COMPULSIVE DISORDER/OCD 
Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors (abst-2010) http://www.ncbi.nlm.nih.gov/pubmed/20695034
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034086/pdf/nihms262924.pdf
Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370
Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug (full-2012) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462012000500008&lng=en&nrm=iso&tlng=en
Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders (full–2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3481531/
Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor (abst–2012) http/www.ncbi.nlm.nih.gov/pubmed/22248639
Cannabidiol reverses the mCPP-induced increase in marble-burying behavior (abst–2013) http/www.ncbi.nlm.nih.gov/pubmed/24118015
β-Caryophyllene, a CB2 Receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice (abst–2014) http/www.ncbi.nlm.nih.gov/pubmed/24930711
Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25340977
The successful use of dronabinol for failure to thrive secondary to intestinal dysmotility (full – 2015) http://www.casereports.com/article/S2210-2612%2815%2900219-9/pdf
Use of Prescription Pain Medications Among Medical Cannabis Patients: Comparisons of Pain Levels, Functioning, and Patterns of Alcohol and Other Drug Use (full-2015) http://ssw.umich.edu/sites/default/files/documents/news/use-of-prescription-pain-medications-amongmedical-cannabis-patients.pdf
Cannabinoids in late-onset Alzheimer’s disease (full-2015) http://onlinelibrary.wiley.com/doi/10.1002/cpt.117/full
With education, nurses can help to bridge the marijuana gap (article-2015) http://cannabistoday.bangordailynews.com/2015/07/09/home/with-education-nurses-can-help-to-bridgethe-marijuana-gap/
Responsible and controlled use: Older cannabis users and harm reduction (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25911027
A safer alternative: Cannabis substitution as harm reduction (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25919477
Kosher marijuana: What would my Bubbie think? (news-2015) http://www.theglobeandmail.com/report-on-business/top-business-stories/kosher-marijuana-what-wouldmy-bubbie-think/article23327496/?cmpid=rss1
How BabyBoomers Get High (news-2015) http://fivethirtyeight.com/datalab/how-baby-boomers-get-high/
Substance abuse risk not greater in those using medical marijuana with prescribed opioids (news-2015) http://www.eurekalert.org/pub_releases/2015-05/joso-sar051115.php
top
Gray hair goes green: Sun City marijuana clinic sees line out door (news-2015) http://www.ktar.com/?nid=22&sid=1836172
What It’s Like To Smoke Pot Every Day For 50 Years (news-2015) https://www.yahoo.com/health/what-its-like-to-smoke-pot-every-day-for-50-years-117780070001.html
Seniors Are Seeking Out States Where Marijuana is Legal (news-2015) http://time.com/money/3967757/seniors-retire-marijuana-legal-states/?xid=yahoo_money
Retirees Represent Major Marijuana Market (news-2015) http://finance.yahoo.com/news/retirees-represent-major-marijuana-market-114038276.html;_ylt=AwrC1jG7MLFVM0UAlFLQtDMD;_ylu=X3oDMTByOHZyb21tBGNvbG8DYmY
xBHBvcwMxBHZ0aWQDBHNlYwNzcg–9 Ways Women And Weed Go Together Like Mary And Jane (news-2015) http://www.huffingtonpost.com/bustle/9-ways-women-and-weed-go-together-like-mary-andjane_b_7100578.html


OLDER ADULT CANNABIS USERS 
Older Adults’ Pot Use Up (news-2010) http://www.dallasnews.com/news/20100223-Older-adults-pot-use-up-7010.ece
Bongs for Boomers: Marijuana Use Increasing Among Seniors (news-2010) http://seniorliving.about.com/b/2010/05/13/bongs-for-boomers-marijuana-use-increasing-amongseniors.htm
Medical Marijuana Raises Tough Questions for Nursing Homes (news-2010) http://newoldage.blogs.nytimes.com/2010/10/27/medical-marijuana-raises-tough-questions-in-nursinghomes/
Marijuana Use By Seniors Goes Up As Boomers Age (news-2010) http://www.mapinc.org/drugnews/v10/n136/a01.html?1189
Pot Breaks the Age Barrier (news-2010) http://www.mapinc.org/drugnews/v10/n233/a01.html?1190
Why Growing Numbers of Baby Boomers and the Elderly Are Smoking Pot (news-2010) http://www.alternet.org/story/145808/why_growing_numbers_of_baby_boomers_and_the_elderly_are_smoking_pot
Pot for Grandma? Middle-Aged Adults Buying Weed for Ailing Parents (news-2010) http://www.parentdish.com/2010/10/11/pot/
Marijuana use among older adults in the U.S.A.: user characteristics, patterns of use, and implications for intervention (abst-2011) http://www.ncbi.nlm.nih.gov/pubmed/21108863
125 Year Old Woman Claimed Smoking Cannabis Everyday Was Her Secret to Long Life (news-2011) http://www.hanf-info.ch/info/en/125-Year-Old-Woman-Claimed-Smoking.html
Cannabis Use in Long-Term Care: An Emerging Issue for Nurses (news-2011) http://www.nursingcenter.com/_PDF_.aspx?an=00000446-201104000-00013
Cannabis Use in Nursing Homes – An Emerging Issue (news-2011) http://berkeleypatientscare.com/2011/12/13/cannabis-use-in-nursing-homes-an-emerging-issue/
Seniors’ Medical Pot Collective Faces Opposition in California (news-2011) http://newsfeed.time.com/2011/06/13/seniors-medical-pot-collective-faces-opposition-incalifornia/#ixzz21IFtpcj1
Prevalences of illicit drug use in people aged 50 years and over from two surveys (full-2012) http://ageing.oxfordjournals.org/content/41/4/553.long
Seniors Benefit Most From Medical Marijuana (news-2012) http://www.doobons.com/blog/2012/04/18/seniors-benefit-most-from-medical-marijuana/
NORML’s Eleven Surprising Things About Marijuana That Seniors Need to Know (news–2012) http://www.theweedblog.com/senior-citizens-need-to-know-the-truth-about-marijuana/
top
Pot smoking not tied to middle-age mental decline (news–2012) http://www.mnn.com/health/fitness-well-being/stories/pot-smoking-not-tied-to-middle-age-mental-decline
Illicit Drug Use Rising For 50+ Crowd (news-2012) http://news.discovery.com/human/drug-use-rising-elderly-120406.html
Reefer tokin’ seniors in South Florida see pain go up in smoke (news-2012) http://articles.sun-sentinel.com/2012-07-23/news/fl-toking-oldsters-20120723_1_reefer-pain-seniors
Silver Tour: Wall Street Journal Looks At Seniors and Medical Marijuana Use (news-2012) http://blog.norml.org/2012/05/29/silver-tour-wall-street-journal-looks-at-seniors-and-medical-marijuanause/
Seniors having Trouble Getting Medical Marijuana (news-2012) http://www.opposingviews.com/i/health/alternative-medicine/seniors-having-trouble-getting-medicalmarijuana
Is Marijuana Booming Among Boomers? (news-2013) http://www.forbes.com/sites/nextavenue/2013/05/16/is-marijuana-booming-among-boomers/
Medical marijuana helps senior sleep, contend with other problems of aging (news-2013) http://www.ottawacitizen.com/health/seniors/Medical+marijuana+helps+senior+sleep+contend+with+other/8439474/story.html
Cannabis for Elders: A Precarious State (news-2013) http://www.theatlantic.com/health/archive/2013/07/cannabis-for-elders-a-precarious-state/278004/
Cannabis Care: Manchester grandmother fears getting caught for using marijuana, waits anxiously for bill to pass (news–2013) http://www.nashuatelegraph.com/news/1011730-469/story.html
Should Your Aging Parent Try Medical Marijuana? (news/anecdotal–2013) http://www.forbes.com/sites/carolynrosenblatt/2013/08/27/should-your-aging-parent-try-medicalmarijuana/?ss=forbeswoman
Marijuana use on the rise among young adults, fiftysomethings (news–2013) http://www.orlandosentinel.com/health/la-sci-sn-drugs-marijuana-survey-20130909,0,5137235.story?track=rss
Senior Focus: Should marijuana be legalized for end of life care? (news–2013) http://www.stltoday.com/lifestyles/health-med-fit/6814b63f-d758-5500-9507-a908a5b20c01.html
New insights into the physiology of bone regulation: the role of neuro-hormones (full-2014) http://www.biomed.cas.cz/physiolres/pdf/prepress/932668.pdf
Therapeutic benefits of cannabis: a patient survey (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998228/
The endocannabinoid system and appetite: relevance for food reward (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24933167
Safety and pharmacokinetics of oral delta-9-tetrahydrocannabinol in healthy older subjects: A randomized controlled trial (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25035121
Boomers’ Need for Weed: Usage Up Significantly Since 2002 (news-2014) http://www.courant.com/features/too-shea/hc-shea-baby-boomers-0326-20140326,0,5472730.column
Retired Flint couple sees the light on medical marijuana (news-2014) http://www.mlive.com/news/flint/index.ssf/2014/04/retired_flint_couple_sees_the.html
Dealing with age (news – 2014) http://www.canberratimes.com.au/national/dealing-with-age-20140707-3bh7k.html
Why marijuana’s moment has arrived (news-2014) http://www.cnn.com/2014/08/11/opinion/zelizer-marijuana-moment-arrives/index.html
top
Monterey County seniors finding pain relief in medical marijuana (news-2014) http://www.montereyherald.com/seniors/ci_26440666/monterey-county-seniors-finding-pain-relief-medical-marijuana?source=rss
Cannabis May Protect The Aging Brain, Say Experts (news-2014) http://www.leafscience.com/2014/05/07/cannabis-may-protect-aging-brain-say-experts/
The successful use of dronabinol for failure to thrive secondary to intestinal dysmotility (full-2015) http://www.casereports.com/article/S2210-2612%2815%2900219-9/pdf
Use of Prescription Pain Medications Among Medical Cannabis Patients: Comparisons of Pain Levels, Functioning, and Patterns of Alcohol and Other Drug Use. (full – 2015) http://ssw.umich.edu/sites/default/files/documents/news/use-of-prescription-pain-medications-amongmedical-cannabis-patients.pdf
Cannabinoids in late-onset Alzheimer’s disease (full–2015) http://onlinelibrary.wiley.com/doi/10.1002/cpt.117/full
With education, nurses can help to bridge the marijuana gap (article–2015) http://cannabistoday.bangordailynews.com/2015/07/09/home/with-education-nurses-can-help-to-bridgethe-marijuana-gap/
Responsible and controlled use: Older cannabis users and harm reduction (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25911027
A safer alternative: Cannabis substitution as harm reduction (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25919477
Kosher marijuana: What would my Bubbie think? (news–2015) http://www.theglobeandmail.com/report-on-business/top-business-stories/kosher-marijuana-what-wouldmy-bubbie-think/article23327496/?cmpid=rss1
How BabyBoomers Get High (news–2015) http://fivethirtyeight.com/datalab/how-baby-boomers-get-high/
Substance abuse risk not greater in those using medical marijuana with prescribed opioids (news-2015) http://www.eurekalert.org/pub_releases/2015-05/joso-sar051115.php
Gray hair goes green: Sun City marijuana clinic sees line out door (news-2015) http://www.ktar.com/?nid=22&sid=1836172
What It’s Like To Smoke Pot Every Day For 50 Years (news–2015) https://www.yahoo.com/health/what-its-like-to-smoke-pot-every-day-for-50-years-117780070001.html
Seniors Are Seeking Out States Where Marijuana is Legal (news-2015) http://time.com/money/3967757/seniors-retire-marijuana-legal-states/?xid=yahoo_money
Retirees Represent Major Marijuana Market (news-2015) http://finance.yahoo.com/news/retirees-represent-major-marijuana-market-114038276.html;_ylt=AwrC1jG7MLFVM0UAlFLQtDMD;_ylu=X3oDMTByOHZyb21tBGNvbG8DYmYxBHBvcwMxBHZ0aWQDBHNlYwNzcg–
9 Ways Women And Weed Go Together Like Mary And Jane (news-2015) http://www.huffingtonpost.com/bustle/9-ways-women-and-weed-go-together-like-mary-andjane_b_7100578.html


OMEGA-3/CB1 CONNECTION
Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?toolubmed
Maternal Dietary Fat Determines Metabolic Profile and the Magnitude of Endocannabinoid Inhibition of the Stress Response in Neonatal Rat Offspring (full-2010) http://endo.endojournals.org/content/151/4/1685.full?sid=f9729cff-d221-42d4-81d8-8545db5df878
Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma (full-2010) http://www.jlr.org/content/51/6/1416.full.pdf+html
top
Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood (abst-2010) http://www.ncbi.nlm.nih.gov/pubmed/20013888
Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice (full-2011) http://www.nutritionandmetabolism.com/content/8/1/51
Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117120/
A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215906/
Greasing the wheels of managing overweight and obesity with omega-3 fatty acids (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210336/
Hepatic n-3 Polyunsaturated Fatty Acid Depletion Promotes Steatosis and Insulin Resistance in Mice: Genomic Analysis of Cellular Targets (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154437/
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21278728
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. Figure 1: n-3/n-6 PUFA dietary imbalance alters PUFAs level in mouse brain. (charts – 2011) http://www.nature.com/neuro/journal/v14/n3/fig_tab/nn.2736_F1.html
Endocannabinoid signaling and energy metabolism: a target for dietary intervention (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21470818
Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21995886
Endocannabinoids: A healthy diet is good for LTD (news–2011) http://www.lipidmaps.org/update/2011/110301/full/nrn2998.html
Omega-3 Fatty Acids Essential for Normal Regulation of Mood in the Brain (news–2011) http://www.elements4health.com/omega-3-fatty-acids-essential-for-normal-regulation-of-mood-in-thebrain.html
Omega-3 deficiency disrupts cannibinoid receptor function in brain (news–2011) http://www.wellsphere.com/general-medicine-article/omega-3-deficiency-disrupts-cannibinoid-receptorfunction-in-brain/1347465
Scientific research reveals brain alterations linking omega 3 deficit with depression (news–2011) http://www.alphagalileo.org/ViewItem.aspx?ItemId=95297&CultureCode=en
What An Expectant Mother Eats Affects Children’s Psychology in Later Life (news–2011) http://nanopatentsandinnovations.blogspot.com/2011/01/what-expectant-mother-eats-affects.html
A Summary of Endocannabinoids and Obesity (news–2011) http://evolutionarypsychiatry.blogspot.com/2011/04/summary-of-endocannabinoids-and-obesity.html
A Brain Wrought Without Omega-3 (news–2011) http://www.schizophreniaforum.org/new/detail.asp?id=1646
Poor Diet Impairs Cannabinoid Receptors (news–2011) http://www.freedomisgreen.com/poor-diet-impairs-cannabinoid-receptors/
Research provides new clues to understand link between deficits of AGPO-3, depression (news–2011) http://www.news-medical.net/news/20110205/Research-provides-new-clues-to-understand-link-betweendeficits-of-AGPO-3-depression.aspx
Why Omega-3s Affect Your Mood (news–2011) http://voices.yahoo.com/why-omega-3s-affect-mood-8180941.html?cat=5
top
Functional Metabolomics Reveals Novel Active Products in the DHA Metabolome (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342038/?toolubmed
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/
Type 2 Diabetes Associated Changes in the Plasma Non-Esterified Fatty Acids, Oxylipins and Endocannabinoids (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493609/
Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483099/
N-acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids – From fishy endocannabinoids to potential leads (full-2012) http://onlinelibrary.wiley.com/doi/10.1111/bph.12030/full
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
Searching for health beneficial n-3 and n-6 fatty acids in plant seeds (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380567/
Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548985/
Nutritional n-3 polyunsaturated fatty acids deficiency alters cannabinoid receptor signaling pathway in the brain and associated anxiety-like behavior in mice (abst-2012) http://www.springerlink.com/content/ur5784gm34782505/
Essential fatty acids and lipid mediators. Endocannabinoids (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/22730630
Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/23103355
Effect of omega-3 polyunsaturated fatty acids on the endocannabinoid system in osteoblast-like cells and muscle (abst-2012) http://docs.lib.purdue.edu/dissertations/AAI3444794/
Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/22805989
Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/22051448
Cannabinoid Receptor Function is Altered by Nutritionally Deficient Diet (news-2012) http://www.examiner.com/medical-marijuana-in-philadelphia/cannabinoid-receptor-function-is-altered-bynutrionally-deficient-diet
Effect of dietary fat type on anxiety-like and depression-like behavior in mice (full-2013) http://www.springerplus.com/content/2/1/165
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men (full-2013) http://www.lipidworld.com/content/12/1/78
Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex (full-2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0081459
top
Nutritional properties of dietary omega-3-enriched phospholipids (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747496/
Association of Expanded Disability Status Scale and Cytokines after Intervention with Co-supplemented Hemp Seed, Evening Primrose Oils and Hot-natured Diet in Multiple Sclerosis Patients (full-2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648912/
Synaptamide, endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function (full-2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541447/
DHA prevents altered 5-HT1(A), 5-HT2(A), CB1 and GABA(A) receptor binding densities in the brain of male rats fed a high-saturated-fat diet (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/23337348
Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/23466458
PUFA-derived endocannabinoids: an overview (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/24020830
Endocannabinoid system as a potential mechanism for n-3 long-chain polyunsaturated fatty acid mediated cardiovascular protection (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/24020800
Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury (full-2013) http://www.sciencedirect.com/science/article/pii/S0306452213007835
Differential Modulation of Tumor Cell Proliferation and their Endocannabinoid System by Polyunsaturated Fatty Acids (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/24138715
Acyl migration evaluation in monoacylglycerols from Echium plantagineum seed oil and Marinol (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/23287502
Polyunsaturated Fatty Acid-Derived Lipid Mediators and T Cell Function (full-2014) http://www.ncbi.nlm.nih.gov/pubmed/24611066
Docosahexaenoyl ethanolamide improves glucose uptake and alters endocannabinoid system gene expression in proliferating and differentiating C2C12 myoblasts. (full – 2014) http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00100/full
Endogenous Signaling by Omega-3 Docosahexaenoic Acid-derived Mediators Sustains Homeostatic Synaptic and Circuitry Integrity (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180614/
Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24518289
Potential Oil Yield, Fatty Acid Composition, and Oxidation Stability of the Hempseed Oil from Four Cannabis sativa L. Cultivars (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24552275
Endocannabinoid signaling and its regulation by nutrients. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24753395
Hempseed oil induces reactive oxygen species- and C/EBP homologous protein-mediated apoptosis in MH7A human rheumatoid arthritis fibroblast-like synovial cells. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24814038
Cannabinoid receptor antagonists and fatty acids alter endocannabinoid system gene expression and COX activity. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24854955
Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24934168
Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target? (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24576779
top
Cannabinoid receptor expression in femora and tibiae of C57/blk6 mice fed DHA and relationship to bone ash and BMC. (bone mineral content) (abst – 2014) http://www.fasebj.org/content/28/1_Supplement/1032.2.abstract?sid=467bb529-0ecc-4ddc-af27-3f56f520a102
Relationship between cannabinoids content and composition of fatty acids in hempseed oils (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25306338
Omega-3 fatty acid production from enzyme saccharified hemp hydrolysate using a novel marine thraustochytrid strain (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25497057
Plant-Based Foods With the Highest Omega-3 Fatty Acids (news – 2014) http://www.onegreenplanet.org/natural-health/plant-based-foods-with-the-highest-amount-of-omega-3-fatty-acids/
Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti-inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages (full–2015) http://onlinelibrary.wiley.com/doi/10.1111/bph.12747/full
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full–2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
Inhibition of COX-2-mediated eicosanoid production plays a major role in the antiinflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages (full–2015) http://onlinelibrary.wiley.com/doi/10.1111/bph.12747/full
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full–2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
Distribution of Bioactive Lipid Mediators in Human Skin (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25668241
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25958314
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26219414
Hemp for a Healthy Heart? (news – 2015) http://blog.lifeextension.com/2014/02/hemp-for-healthy-heart.html
The Benefits of Organic Hemp Milk (news – 2015) http://www.globalhealingcenter.com/natural-health/benefits-of-hemp-milk/


OMEGA-6/ENDOCANNABINOID CONNECTION
Endocannabinoids are made from Omega 6 – you need it, but it is also pro-inflammatory, so too much is not good for you!
Exposure to a high-fat diet decreases sensitivity to Δ9-tetrahydrocannabinol-induced motor effects in female rats (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014410/
Hepatic n-3 Polyunsaturated Fatty Acid Depletion Promotes Steatosis and Insulin Resistance in Mice: Genomic Analysis of Cellular Targets (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154437/
Endocannabinoid signaling and energy metabolism: a target for dietary intervention (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21470818
A Summary of Endocannabinoids and Obesity (news–2011) http://evolutionarypsychiatry.blogspot.com/2011/04/summary-of-endocannabinoids-and-obesity.html
Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548985/
top
N-acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids – From fishy endocannabinoids to potential leads (full – 2012) http://onlinelibrary.wiley.com/doi/10.1111/bph.12030/full
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/
Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483099/
Searching for health beneficial n-3 and n-6 fatty acids in plant seeds (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380567/
Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23103355
Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex (full – 2013)  http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0081459
Association of Expanded Disability Status Scale and Cytokines after Intervention with Co-supplemented Hemp Seed, Evening Primrose Oils and Hot-natured Diet in Multiple Sclerosis Patients (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648912/
PUFA-derived endocannabinoids: an overview. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24020830
Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system (abst – 2013) http://onlinelibrary.wiley.com/doi/10.1002/jnr.23231/abstract
Polyunsaturated Fatty Acid-Derived Lipid Mediators and T Cell Function (full – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24611066
Docosahexaenoyl ethanolamide improves glucose uptake and alters endocannabinoid system gene expression in proliferating and differentiating C2C12 myoblasts (full – 2014) http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00100/full
Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24518289
Potential Oil Yield, Fatty Acid Composition, and Oxidation Stability of the Hempseed Oil from Four Cannabis sativa L. Cultivars (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24552275
Endocannabinoid signaling and its regulation by nutrients. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24753395
Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target? (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24576779
Gamma-linolenic acid egg production enriched with hemp seed oil and evening primrose oil in diet of laying hens (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25004746
Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24934168
Relationship between cannabinoids content and composition of fatty acids in hemp seed oils (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25306338
Plant-Based Foods With the Highest Omega-3 Fatty Acids (news-2014) http://www.onegreenplanet.org/natural-health/plant-based-foods-with-the-highest-amount-of-omega-3-fatty-acids/
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full–2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
top
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25958314
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26219414
The Benefits of Organic Hemp Milk (news-2015) http://www.globalhealingcenter.com/natural-health/benefits-of-hemp-milk/


OMEGA-9
Pitfalls in the sample preparation and analysis of N-acylethanolamines (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936757/
Targeted mutation of Δ12 and Δ15 desaturase genes in hemp produce major alterations in seed fatty acid composition including a high oleic hemp oil (full-2014) http://onlinelibrary.wiley.com/doi/10.1111/pbi.12167/epdf
Your Next Cooking Oil Could Come From Hemp (news – 2014) http://www.popsci.com/article/science/your-next-cooking-oil-could-come-hemp


ORGAN TRANSPLANTS
Do cannabinoids have a therapeutic role in transplantation? (full–2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2923447/?toolubmed
Denial of hepatic transplantation on the basis of smoking: is it ethical? (abst–2010) http/www.ncbi.nlm.nih.gov/pubmed/20154621
Oregon hospitals denying life saving organ transplants to legal medical marijuana patients (news-2010) http/www.huffingtonpost.com/russ-belville/oregon-hospitals-denying_b_575965.html
Health Tragedy: Patients Denied Life-Saving Transplants for Their “Abuse of Illicit Substances” (news–2010) http/www.alternet.org/health/145432/health_tragedy%3A_patients_denied_lifesaving_transplants_for_their_%22abuse_of_illicit_substances%22
Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model (full-2011) http/jpet.aspetjournals.org/content/early/2011/06/14/jpet.111.182717.long
The Denial of Organ Transplants to Medical Marijuana Patients (news-2011) http/www.huffingtonpost.com/russ-belville/the-denial-of-organ-trans_b_435348.html
Cancer Patient Taken Off Of Liver Transplant List Because Of Medical Marijuana Use (news-2011) http/www.huffingtonpost.com/2011/12/05/norman-smith-cancer_n_1130619.html
Cedars-Sinai Denying Transplant To Medical Marijuana Patient With Inoperable Liver Cancer (news-2011) http/www.cannabisculture.com/v2/content/2011/11/17/Cedars-Sinai-Denying-Transplant-Medical-Marijuana-Patient-Inoperable-Liver-Cancer
Cannabinoids Inhibit T-cells via Cannabinoid Receptor 2 in an In Vitro Assay for Graft Rejection, the Mixed Lymphocyte Reaction (abst–2013) http/www.ncbi.nlm.nih.gov/pubmed/23824763
N.J. Assembly approves bill protecting marijuana patients (news-2013) http/www.philly.com/philly/news/20130524_N_J__Assembly_approves_bill_protecting_marijuana_patients.html
N-acyl dopamine derivates as lead compound for implementation in transplantation medicine (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25576467
Effects of Cannabinoids on T-cell Function and Resistance to Infection (full-2015) http://tinyurl.com/o3jbfsd
Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury (full-2015) http://www.karger.com/Article/Pdf/430165
top
N-acyl dopamine derivates as lead compound for implementation in transplantation medicine (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25576467
The cannabinoid receptor 2 is involved in acute rejection of cardiac allografts (abst–2015) http://www.sciencedirect.com/science/article/pii/S0024320515001290
Δ9-Tetrahydrocannabinol attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells. (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26034207
Cannabidiol for the Prevention of Graft-Versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26033282
Circulating endocannabinoids during hematopoietic stem cell transplantation: A pilot study (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26114153
California Legislator Introduces Bill to End Organ Transplant Denials for Medical Marijuana Patients (news–2015)
http://www.commondreams.org/newswire/2015/02/12/california-legislator-introduces-bill-end-organtransplant-denials-medical


OSTEOPOROSIS/BONES and CARTILAGE
Hypothalamic regulation of bone (full–2010) http://jme.endocrinology-journals.org/cgi/content/full/45/4/175
Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001217/?toolubmed
Tissue Engineering of Cartilage; Can Cannabinoids Help? (full–2010) http://www.tara.tcd.ie/bitstream/2262/40674/1/Tissue%20Engineering%20of%20Cartilage%20-%20Can%20Cannabinoids%20Help.pdf
Endocannabinoids Are Expressed in Bone Marrow Stromal Niches and Play a Role in Interactions of Hematopoietic Stem and Progenitor Cells with the Bone Marrow Microenvironment (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975171/?toolubmed
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871326/
Cannabinoids and Bone: Friend or Foe? (abst-2010) http://www.ncbi.nlm.nih.gov/pubmed/20532878
The endocannabinoid signaling system: a marriage of PUFA and musculoskeletal health (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20934863
Control of bone remodeling by nervous system. Nervous system and bone (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/21123931
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro (full–2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01519.x/full
The Type 2 Cannabinoid Receptor Regulates Bone Mass and Ovariectomy-Induced Bone Loss by Affecting Osteoblast Differentiation and Bone Formation (full–2011) http://press.endocrine.org/doi/full/10.1210/en.2010-0930
Skeletal lipidomics: regulation of bone metabolism by fatty acid amide family (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165954/
The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21237298
top
The role of cannabinoid receptors in bone remodeling in a CB1/2 double knockout mouse (abst–2011) http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/492.5?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcetype=HWCIT
Role of cannabinoids in the regulation of bone remodeling (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499879/
Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with up-regulation of CB1 and CB2 (abst-2012) http://www.ncbi.nlm.nih.gov/pubmed/22366523
THE CO-EXPRESSION OF THE ENDOCANNABINOID SYSTEM AND THE RANK/RANKL SIGNALLING PATHWAY IN HUMAN BONE AND OSTEOCLAST CULTURE (abst-2012) http://www.bjjprocs.boneandjoint.org.uk/content/94-B/SUPP_XVIII/7.abstract?maxtoshow=&hits=25&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=130&sortspec=date&resourcetype=HWCIT
Cannabinoids: novel therapies for arthritis? (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22530636
Magnolol Ameliorates Ligature-Induced Periodontitis in Rats and Osteoclastogenesis: In Vivo and In Vitro Study (full-2013) http://www.hindawi.com/journals/ecam/2013/634095/
Cannabinoid WIN-55,212-2 Mesylate Inhibits Interleukin-1β Induced Matrix Metalloproteinase and Tissue Inhibitor of Matrix Metalloproteinase Expression in Human Chondrocytes (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/24211233
Increase of mesenchymal stem cell migration by Cannabidiol via activation of p42/44 MAPK (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/24304686
Modulation of Strain-Specific Differences in Gene Expression by Cannabinoid Type 2 Receptor Deficiency (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/24370613
New insights into the physiology of bone regulation: the role of neuro-hormones (full-2014) http://www.biomed.cas.cz/physiolres/pdf/prepress/932668.pdf
Therapeutical Potential of CB2 Receptors in Immune-Related Diseases (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24720538
Cannabinoid receptor expression in femora and tibiae of C57/blk6 mice fed DHA and relationship to bone ash and BMC. (bone mineral content) (abst-2014) http://www.fasebj.org/content/28/1_Supplement/1032.2.abstract?sid=467bb529-0ecc-4ddc-af27-3f56f520a102
Protection from osteoarthritis may lie in our own joints, study suggests (news-2014) http://www.alphagalileo.org/ViewItem.aspx?ItemId=141814&CultureCode=en
Activation of Cannabinoid Receptor 2 Enhances Osteogenic Differentiation of Bone Marrow Derived Mesenchymal Stem Cells (full-2015) http://www.hindawi.com/journals/bmri/2015/874982/
CB1 cannabinoid receptors mediate endochondral skeletal growth attenuation by Δ9-tetrahydrocannabinol (full-2015) http://onlinelibrary.wiley.com/doi/10.1111/nyas.12642/full
Dose-response estrogen promotes osteogenic differentiation via GPR40 (FFAR1) in murine BMMSCs (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25576830
San Francisco Medical Marijuana Clinic Says Cannabis is Effective for Many Women’s Medical Issues (news-2015) http://www.prweb.com/releases/marijuana-doctor/san-francisco/prweb8668761.htm
Weed: Good for the Bones? (news – 2015) http://news.yahoo.com/weed-good-bones-151615912.html;_ylt=AwrXgiKs7r9VlUsAmDbQtDMD;_ylu=X3oDMTByYnR1Zmd1BGNvbG8DZ3ExBHBvcwMyBHZ0aWQDBHNlYwNzcg–
Study: Cannabis helps to heal bone fractures (news-2015) http://www.upi.com/Health_News/2015/07/16/Study-Cannabis-helps-to-heal-bonefractures/9431437083214/
No bones about it: Cannabis may be used to treat fractures (news-2015) http://medicalxpress.com/news/2015-07-bones-cannabis-fractures.html
top


OVARIAN CYSTS
Lack of association between C385A functional polymorphism of the fatty acid amide hydrolase gene and polycystic ovary syndrome (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/23616186
Relationship between leptin receptor and polycystic ovary syndrome (abst-2013) http://www.ncbi.nlm.nih.gov/pubmed/23769971
Cannabinoid receptor 1 gene polymorphisms and nonalcoholic Fatty liver disease in women with polycystic ovary syndrome and in healthy controls (full-2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127238/
Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25093427
Endocannabinoid system activation may be associated with insulin resistance in women with polycystic ovary syndrome (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25935491


OVERDOSES on CANNABINOIDS
Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada) (full–2010) http://www.hc-sc.gc.ca/dhp-mps/marihuana/med/infoprof-eng.php
Accidental cannabis poisoning in children: report of four cases in a tertiary care center from southern Spain (abst–2011) http://www.unboundmedicine.com/medline/ebm/record/21283933/abstract/%5BAccidental_cannabis_poisoning_in_children:_report_of_four_cases_in_a_tertiary_care_center_from_southern_Spain%5D_
Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine (abst–2011) http://www.unboundmedicine.com/medline/ebm/record/20634020/abstract/Prolonged_coma_in_a_child_due_to_hashish_ingestion_with_quantitation_of_THC_metabolites_in_urine_
Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature (full – 2012) http://www.harmreductionjournal.com/content/9/1/7
Acute cannabis poisoning in a 10-month-old infant. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22652516
Recreational use and overdose of ingested processed cannabis (Majoon Birjandi) in the eastern Iran (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22751199
Of Edibles And Overdosing (news – 2012) http://beyondchronic.com/2012/04/edibles-and-overdosing/#comment-2799
How Much Marijuana Does It Take For Someone To Overdose? (news–2013) http://www.theweedblog.com/how-much-marijuana-does-it-take-for-someone-to-overdose/
Scientists Explain Why Marijuana Users Never Overdose (news–2014) http://www.leafscience.com/2014/01/08/scientists-explain-marijuana-users-never-overdose/
Why Eating A Marijuana Candy Bar Sent Maureen Dowd To Paranoia Hell (news-2014) http://www.forbes.com/sites/daviddisalvo/2014/06/09/why-eating-a-marijuana-candy-bar-sent-maureendowd-to-paranoia-hell/
MEDICAL MARIJUANA : Out of the Shadows (news-2014) http://cannabisclinicians.org/wp-content/uploads/2014/04/SCMA-Spring-2014-Kerr.pdf
top
A non-classical cannabinoid syndrome (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25567676
A cannabinoid-intoxicated child treated with dexmedetomidine: a case report (full-2015) http://www.jmedicalcasereports.com/content/9/1/152
Notes from the Field: Death Following Ingestion of an Edible Marijuana Product – Colorado, March 2014 (full-2015)
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6428a6.htm
A non-classical cannabinoid syndrome (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25567676


OVERVIEWS
Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada) (full-2010) http://www.hc-sc.gc.ca/dhp-mps/marihuana/med/infoprof-eng.php
Cannabis and Its Derivatives: Review of Medical Use (full–2011) http://www.jabfm.org/cgi/content/full/24/4/452
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
Global Commission Drug Report (links to full in various languages-2011) http://www.globalcommissionondrugs.org/Report
Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed (full-2011) (deceptive title) http://www.hanf-info.ch/info/en/IMG/pdf/EIHA-11-05-31_EIHA-Statement_on_THC_in_feed.pdf
Introduction to the Endocannabinoid System (news-2011) http://norml.org/index.cfm?Group_ID=8444
Is Pot Good For You? (news-2011) http://www.maps.org/media/view/is_pot_good_for_you/
The Therapeutic Potential of Cannabis and Cannabinoids (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442177/
Blurred Boundaries: The Therapeutics and Politics of Medical Marijuana (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538401/
2012 Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective (full-2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064474/
The Legalization of Marijuana in Colorado: The Impact. Rocky Mountain HIDTA. The Impact (full-2014) http://www.rmhidta.org/html/August%202014%20Legalization%20of%20MJ%20in%20Colorado%20the
%20Impact.pdf
Medical Cannabis Research, What the Science Says (article-2014) http://www.safeaccessnow.org/medical_cannabis_research_what_does_the_evidence_say
Cannabis conundrum: Evidence of harm?: Opposition to marijuana use is often rooted in arguments about the drug’s harm to children and adults, but the scientific evidence is seldom clear-cut (Part 1 of 2) (article-2015) http://onlinelibrary.wiley.com/doi/10.1002/cncy.21516/full
Medical marijuana: Hints of headway? Despite a conflicted regulatory landscape, support for medical marijuana is growing amid increasing evidence of potential benefits (Part 2 of 2) (article-2015) http://onlinelibrary.wiley.com/doi/10.1002/cncy.21524/full
Endocannabinoids (article-2015) http://emedicine.medscape.com/article/1361971-overview#showall
Marijuana Legalization and Decriminalization Overview (article-2015) http://criminal.findlaw.com/criminal-charges/marijuana-legalization-and-decriminalizationoverview.html#sthash.yjNdUJjQ.dpuf
What 7 States Discovered After Spending More Than $1Million Drug Testing Welfare Recipients (news-2015) http://thinkprogress.org/economy/2015/02/26/3624447/tanf-drug-testing-states/
Medical Marijuana: Benefits, Risks & State Laws (news-2015) http://www.livescience.com/24554-medical-marijuana.html
top