O-P (Pre-2000)

OBESITY
OMEGA-3 / CB1 CONNECTION (Without Omega-3, New CB1 Receptors are Made Imperfectly. See Also NUTRITION-HEMP SEED OIL, CBR-CB1 RECEPTORS)
OMEGA-6 / ENDOCANNABINOID CONNECTION (Endocannabinoids Are Made From Omega-6)
ORGAN TRANSPLANTS
OVERDOSES on CANNABINOIDS (See Also CANNABINOID HYPEREMESIS SYNDROME, SPICE)
OVERVIEWS
PAIN
PARKINSON’S DISEASE
PATENTS RELATED TO CANNABIS
PEA – PALMITOYLETHANOLAMIDE (Endocannabinoid , CB2, GPR55 and GPR119 Agonist)
POISONING-HEAVY METAL
POISONING-PARAQUAT
POST-TRAUMATIC STRESS DISORDER / PTSD
POTENCY – THE “HIGH”
PREGNANCY / PRENATAL EXPOSURE (See Also PERINATAL HYPOXIC-ISCHEMIC INJURY, CHILDREN / YOUNG ADULTS)


OBESITY
Hemp & GLA: Good Fat Burns Bad Fat (news-forum repost-undated) http://www.420magazine.com/forums/hemp-seed-oil/177358-hemp-gla-good-fat-burns-bad-fat.html
Inhalation of tobacco and marijuana in dog over a period of 30 months: effect on body weight, food intake and organ weight (abst–1976) http://www.ncbi.nlm.nih.gov/pubmed/935636
Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory (abst-1988) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=117


OMEGA-3 / CB1 CONNECTION
Omega-3 and Omega-6 Essential fatty Acids (EFA) (infomercial/ad–undated) http://www.advance-health.com/efa.html
Occurrence of “omega-3” stearidonic acid in hemp seed (full-1996) http://www.hempfood.com/IHA/iha03208.html
Recent advances in the biology of n-6 fatty acids (abst–1997) http://www.nutritionjrnl.com/article/S0899-9007%2897%2900341-9/abstract


OMEGA-6 / ENDOCANNABINOID CONNECTION
Recent advances in the biology of n-6 fatty acids (abst–1997) http://www.nutritionjrnl.com/article/S0899-9007%2897%2900341-9/abstract
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ORGAN TRANSPLANTS
Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient (full-1988) http://journal.publications.chestnet.org/data/Journals/CHEST/21581/432.pdf
Successfully treated invasive pulmonary aspergillosis associated with smoking marijuana in a renal transplant recipient (abst-1996) http://www.ncbi.nlm.nih.gov/pubmed/8685958


OVERDOSES on CANNABINOIDS
What is the lethal dose of marijuana? (news–undated) http://druglibrary.org/schaffer/library/mj_overdose.htm
An Overdose of Hasheesh (1884) http://www.popsci.com/archive-viewer?id=vCoDAAAAMBAJ&pg=509
Cannabis Indica Poisoning (1899) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s2_2.pdf
Two cases of Poisoning by Cannabis Indica (1900) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s2_3.pdf
Collapse after intravenous injection of hashish (full-1968) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1986226/?tool=pmcentrez&page=1
Accidental Overdose Intoxication: A Hazard of Drug Smuggling (full-1982) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552908/?tool=pmcentrez&page=1


OVERVIEWS
On Being Stoned: A Psychological Study of Marijuana Intoxication (book-1971) http://www.druglibrary.org/special/tart/tartcont.htm
HEMP, THE PLANT THAT CAN SAVE MOTHER EARTH (transcript–1990) http://www.ratical.org/renewables/hempHDRT.html


PAIN
ANTI-EDEMA AND ANALGESIC PROPERTIES OF Δ9-TETRAHYDROCANNABINOL (THC) (abst-1973) http://jpet.aspetjournals.org/content/186/3/646.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=2160&resourcetype=HWCIT
Analgesic effect of delta-9-tetrahydrocannabinol (abst-1975) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=16
The analgesic properties of delta-9-tetrahydrocannabinol and codeine (abst-1975) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=17
Marihuana as a therapeutic agent for muscle spasm or spasticity (abst-1980) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=53
ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L (full-1988) http://www.ukcia.org/research/AnalgesicAndAntiInflammatoryActivityofConstituents.html
The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients (abst-1996) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=12
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The perceived effects of smoked cannabis on patients with multiple sclerosis (abst-1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13
Pain relief with oral cannabinoids in familial Mediterranean fever (abst-1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=18
Hypoactivity of the Spinal Cannabinoid System Results in NMDA-Dependent Hyperalgesia (full–1998) http://www.jneurosci.org/content/18/1/451.long
Doped skin (news–forum repost-1998) http://www.420magazine.com/forums/anandamide-aea/145259-doped-skin.html
Pain modulation by release of the endogenous cannabinoid anandamide (full-1999) http://www.pnas.org/content/96/21/12198.full
Analgesic effect of the cannabinoid analogue nabilone is not mediated by opioid receptors (abst-1999) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=203
Brain Releases Marijuana-Like Substance In Response To Pain, Study Finds (news-1999) http://www.sciencedaily.com/releases/1999/10/991013074947.htm


PARKINSON’S DISEASE
Tetrahydrocannabinol potentiates reserpine-induced hypokinesia (abst–1981) http://www.ncbi.nlm.nih.gov/pubmed/6273940
Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced dystonic dyskinesia (abst-1985) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=142
Open label evaluation of cannabidiol in dystonic movement disorders (full-1986) http://web.acsalaska.net/~warmgun/es017.html
The effects of the cannabinoid receptor agonist nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson’s disease (PD) (abst-1998) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=153
Cannabis in movement disorders (abst-1999) http://www.ncbi.nlm.nih.gov/pubmed/10627163
Why your brain is primed for a high (news-1999) http://www.mapinc.org/drugnews/v99.n362.a08.html


PATENTS RELATED TO CANNABIS
US Patent 4189491 – Tetrahydrocannabinol in a method of treating glaucoma (full-1980) http://www.google.com/patents/US4189491
Patent 4315862 – Process for preparing cannabichromene (full-1982) http://www.freepatentsonline.com/4315862.html
Patent 4758597 Cannabidiol and derivatives (full–1988) http://www.google.com.ar/patents/US4758597
European Patent EP0494665 – A method for the production of 6,12-dihydro-6-hydroxycannabidiol and the use thereof for the production of transdelta-9-tetrahydrocannabinol (full–1995) http://www.freepatentsonline.com/EP0494665.html
US Patent 5389375 – Stable suppository formulations effecting bioavailability of Ɗ9 -thc (full-1995) http://www.patents.com/us-5389375.html
US Patent 5508037 – Stable suppository formulations effecting bioavailability of Ɗ9 -THC (full-1996) http://www.patents.com/us-5508037.html
Patent 5605928 – Antiemetic compositions (full–1997) http://www.google.com/patents/US5605928
Patent 5631297 – Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same (full–1997) http://www.freepatentsonline.com/5631297.html
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Marinol vs. Marijuana: Politics, Science, and Popular Culture (article–1997) http://members.iowatelecom.net/sharkhaus/marinol_long.html


PEA – PALMITOYLETHANOLAMIDE
Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide (full–1995) http://www.pnas.org/content/92/8/3376.full.pdf+html
The palmitoylethanolamide and oleamide enigmas : are these two fatty acid amides cannabimimetic? (abst–1999) http://www.ncbi.nlm.nih.gov/pubmed/10469890


PHYTOCANNABINOIDS / PLANT EXTRACTS
Phytocannabinoids (news–undated) http://www.news-medical.net/health/Phytocannabinoids.aspx
ACCESSING 0.5 to 2.0 GRAMS CBD FRACTIONATING THE PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS (article–forum repost-undated) http://forum.grasscity.com/medical-marijuana/610429-need-cbd.html
Cannabinoids (encyclopedia entry) http://www.chemie.de/lexikon/e/Cannabinoids/
Cannabis Indica (U. S. P.)-Indian Cannabis. King’s American Dispensatory (1898) http://www.henriettesherbal.com/eclectic/kings/cannabis.html
The physiological activity of cannabis sativa. Comparison of extracts from indian and American-grown drug upon human subjects (1st page–1913) http://onlinelibrary.wiley.com/doi/10.1002/jps.3080020104/abstract
The effects of large doses of Cannabis indica (1st page–1923) http://onlinelibrary.wiley.com/doi/10.1002/jps.3080120305/abstract
Chemical basis of hashish activity (abst-1970) http://www.ncbi.nlm.nih.gov/pubmed/4987683
Anticonvulsant Action of Cannabis in the Rat: Role of Brain Monoamines (abst–1978) http://www.ncbi.nlm.nih.gov/pubmed/104333
Intraocular pressure following systemic administration of cannabinoids (abst-1982) http://www.ncbi.nlm.nih.gov/pubmed/6295702
Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol (abst–1984) http://www.ncbi.nlm.nih.gov/pubmed/6098513
Developmental aspects of anandamide: ontogeny of response and prenatal exposure (abst–1996) http://www.psyneuen-journal.com/article/0306-4530%2895%2900039-9/abstract
Side effects of pharmaceuticals not elicited by comparable herbal medicines: the case of tetrahydrocannabinol and marijuana (abst–1999) http://www.ncbi.nlm.nih.gov/pubmed/10394675


POISONING – HEAVY METAL
Accumulation of various N-acylethanolamines including N-arachidonoylethanolamine
(anandamide) in cadmium chloride-administered rat testis (abst–1998) http://www.ncbi.nlm.nih.gov/pubmed/9637740


POISONING – PARAQUAT
Paraquat goes to pot (full-1978) http://journal.publications.chestnet.org/article.aspx?articleid=1049877
Paraquat and marihuana. Assessing the hazard (full-1978) http://journal.publications.chestnet.org/article.aspx?articleid=1049876
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An effect of paraquat on the lungs of rabbits. Its implications in smoking contaminated marihuana (full-1978) http://journal.publications.chestnet.org/data/Journals/CHEST/21013/418.pdf
The City, The State And Paraquat (news–1978) http://www.thecrimson.com/article/1978/5/10/the-city-the-state-and-paraquat/
Paraquat and marijuana: epidemiologic risk assessment (full-1983) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1650884&tool=pmcentrez
U.S. to Resume Using Paraquat on Marijuana (news–1988) http://www.nytimes.com/1988/07/14/us/us-to-resume-using-paraquat-on-marijuana.html


POST TRAUMATIC STRESS DISORDER / PTSD
Chronic PTSD in Vietnam combat veterans: course of illness and substance abuse (abst–1996) http://www.ncbi.nlm.nih.gov/pubmed/8610824


POTENCY / THE “HIGH”
What Medical Marijuana strain is best for your condition, Sativa or Indica? (news–undated) http://patientsmarijuana.org/Sativa_or_Indica.html
Problems of modern hemp breeding, with particular reference to the breeding of varieties of hemp containing little or no hashish (full–1956) http://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1956-01-01_3_page007.html
A note on the cannabinoid content of Jamaican ganja (abst–1976) http://www.ncbi.nlm.nih.gov/pubmed/1051625
An investigation of procedures reported to increase potency of marijuana: a chemical analysis and psychological interpretation (abst–1978) http://www.ncbi.nlm.nih.gov/pubmed/721338
Variation in the THC content in illicitly imported Cannabis products–Part II (abst–1982) http://www.ncbi.nlm.nih.gov/pubmed/6303481
UV-B radiation effects on photosynthesis, growth and cannabinoid production of two Cannabis sativa chemotypes (abst–1987) http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.1987.tb04757.x/abstract;jsessionid=E27DFF97974EDECC7DCDFFD1EED18D17.d03t03
Stability of Cannabinoids in Dried Samples of Cannabis Dating from Around 1896-1905 (abst–1990) http://www.ncbi.nlm.nih.gov/pubmed/2314109
Variation in the THC content of illicitly imported Cannabis products–1984-1989 (abst–1990) http://www.ncbi.nlm.nih.gov/pubmed/1983141
Characterization of the lipophilicity of natural and synthetic analogs of delta 9-tetrahydrocannabinol and its relationship to pharmacological potency (abst-1990) http://jpet.aspetjournals.org/content/255/2/624.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Response to marijuana as a function of potency and breathhold duration (abst-1991) http://www.ncbi.nlm.nih.gov/pubmed/2027922?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=1&log$=relatedarticles&logdbfrom=pubmed
Marijuana smoking: effect of varying delta 9-tetrahydrocannabinol content and number of puffs (abst-1992) http://jpet.aspetjournals.org/content/261/1/114.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=480&resourcetype=HWCIT
Effects of delta 9-THC on marijuana smoking, dose choice, and verbal report of drug liking (full-1994) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334408/?tool=pubmed
Preference for High- Versus Low-potency Marijuana (abst–1994) http://www.ncbi.nlm.nih.gov/pubmed/7862719
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Effects of Varying Marijuana Potency on Deposition of Tar and D 9 -THC in the Lung During Smoking (full-1997) http://www.ukcia.org/research/EffectsOfVaryingMarijuanaPotency.pdf
Hemp and Marijuana:Myths & Realities (full–1998) http://www.naihc.org/hemp_information/content/hemp.mj.html
Medical Cannabis Potency Testing Project (full-1999) http://www.maps.org/news-letters/v09n3/09320gie.html
Cannabis as an illicit crop: recent developments in cultivation and product quality (full–1999) http://static.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1997-01-01_1_page002.html


PREGNANCY / PRENATAL EXPOSURE
Effects of Alcohol and Cannabis during Labor (article-forum repost-1930) http://www.420magazine.com/forums/historical-studies-pre-1937/150563-effects-alcohol-cannabis-duringlabor.html
Nonmutagenic action of cannabinoids in vitro (abst-1978) http://content.karger.com/ProdukteDB/produkte.asp?Doi=136789
Teratologic evaluation of synthetic delta 9-tetrahydrocannabinol in rabbits (abst–1979) http://www.ncbi.nlm.nih.gov/pubmed/473088
Acute effects of marihuana smoking on prolactin levels in human females (abst-1985) http://jpet.aspetjournals.org/content/232/1/220.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Effects of prenatal exposure to cannabinoids (abst–1985) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=3929130&dopt=abstractplus
Tolerance to the luteinizing hormone and prolactin suppressive effects of delta-9-tetrahydrocannabinol develops during chronic prepubertal treatment of female rats (abst-1986) http://jpet.aspetjournals.org/content/238/3/1034.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT
A comparison of the effects of prenatal exposure to tobacco, alcohol, cannabis and caffeine on birth size and subsequent growth (abst-1987) http://www.ncbi.nlm.nih.gov/pubmed/3657756
Poor and pregnant: perinatal ganja use in rural Jamaica (abst–1989) http://www.ncbi.nlm.nih.gov/pubmed/2785329
SCIENCE WATCH; Marijuana Medication (news–1993) http://www.nytimes.com/1993/06/01/science/science-watch-marijuana-medication.html?src=pm
Marijuana Use in Pregnancy and Pregnancy Outcome (abst–1990) https://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-999442
Five-year follow-up of rural Jamaican children whose mothers used marijuana during pregnancy (abst–1991) http://www.ncbi.nlm.nih.gov/pubmed/1957518
Prenatal marijuana use and neonatal outcome (abst–1991) http://www.ncbi.nlm.nih.gov/pubmed/1886543
Analysis of Facial Shape in Children Gestationally Exposed to Marijuana, Alcohol, and/or Cocaine (abst-1992) http://pediatrics.aappublications.org/cgi/content/abstract/89/1/67?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=960&resourcetype=HWCIT
Tobacco and marijuana use on offspring growth from birth through 3 years of age (abst-1992) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=1488035&ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
THREE THINGS MARIJUANA DOESN’T DO (news-1992) http://www.ukcia.org/research/mjfaq2.php
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Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica : An Ethnographic Study (full-1994) http://www.druglibrary.org/Schaffer/hemp/medical/can-babies.htm
The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling (full-1995) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC40821/
Prenatal exposure to marihuana and tobacco during infancy, early and middle childhood: effects and an attempt at synthesis (abst–1995) http://www.ncbi.nlm.nih.gov/pubmed/7786162
Prenatal tobacco and marijuana use among adolescents: effects on offspring gestational age, growth, and morphology (abst–1995) http://www.ncbi.nlm.nih.gov/pubmed/7724314
Mortality Within the First 2 Years in Infants Exposed to Cocaine, Opiate, or Cannabinoid During Gestation (abst-1997) http://pediatrics.aappublications.org/cgi/content/abstract/100/1/79?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT
Maternal cannabis use and birth weight: a meta-analysis (abst–1997) http://www.ingentaconnect.com/content/carfax/cadd/1997/00000092/00000011/art00015
Use of Marijuana During Pregnancy (book excerpt-1997) http://www.mothering.com/articles/use-of-marijuana-during-pregnancy/
Dr. Melanie Dreher, reefer researcher (interview-1998) http://www.cannabisculture.com/v2/articles/1404.html
Cannabis and pregnancy (full-1999) http://www.ukcia.org/research/CannabisAndPregnancy.php
Ganja mothers, ganja babies (news-1999) http://www.cannabisculture.com/articles/1422.html