L

+ Studies in 2000-2009 List
* Studies in Pre-2000 List

LEGIONNAIRES DISEASE +
LEISHMANIASIS +
LIVER DISEASE-NON HEPATITIS*+ (See Also HEPATITIS)
LONG TERM USE EFFECTS*+
LUNG FUNCTION*+
LUPUS ERYTHEMATOSUS
LYME DISEASE +


LEGIONNAIRES DISEASE
Legionnaires disease in cannabis smokers (full-2011) http://journal.publications.chestnet.org/article.aspx?articleid=1086681


LEISHMANIASIS 
Antileishmanial phytochemical phenolics: Molecular docking to potential protein targets (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24463105
top


LIVER DISEASE-NON HEPATITIS
Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2 (link to PDF-2015) http://www.mdpi.com/1420-3049/20/1/1277
Two non-psychoactive cannabinoids reduce intra-cellular lipid levels and inhibit hepatosteatosis (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25595882
Protective Role of CB2 Receptor Activation in Galactosamine/LPS-induced Acute Liver Failure Through Regulation of Macrophage Polarization and miRNAs (full-2015) http://jpet.aspetjournals.org/content/early/2015/03/06/jpet.114.220368.long
Cannabidiol Rescues Acute Hepatic Toxicity and Seizure Induced by Cocaine (full-2015) http://www.hindawi.com/journals/mi/2015/523418/
Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury (full-2015) http://www.karger.com/Article/Pdf/430165
Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2. (link to PDF-2015)
http://www.mdpi.com/1420-3049/20/1/1277
Two non-psychoactive cannabinoids reduce intra-cellular lipid levels and inhibit hepatosteatosis (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25595882
Anandamide Drives Cell Cycle Progression through CB1 Receptors in a Rat Model of Synchronized Liver Regeneration (abst–2015)
http://www.ncbi.nlm.nih.gov/pubmed/25684344
Rimonabant inhibits proliferation, collagen secretion and induces apoptosis in hepatic stellate cells (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25713910
Major urinary protein 1 interacts with cannabinoid receptor type 1 in fatty acid-induced hepatic insulin resistance in a mouse hepatocyte model (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25843798
Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoylglycerol and arachidonoyl-ethanolamide, and their metabolites. (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25877930
The effect of endocannabinoid system in ischemia-reperfusion injury: a friend or a foe? (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25936364


LONG TERM USE EFFECTS
Effects of cannabis on lung function: a population-based cohort study (full-2010) http://erj.ersjournals.com/content/35/1/42.long
Light Marijuana Use Appears Protective Against Diabetes (news-2010) http://www.clinicalpsychiatrynews.com/index.php?id=2407&cHash=071010&tx_ttnews%5Btt_news%5D=41212
Tolerance and cross-tolerance to neurocognitive effects of THC and alcohol in heavy cannabis users (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045517/
Increased Blood Pressure Following Abrupt Cessation of Daily Cannabis Use (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045206/
Effects of Chronic Marijuana Use on Brain Activity During Monetary Decision-Making (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260974/
top
Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed (full-2011) (deceptive title) http://www.hanf-info.ch/info/en/IMG/pdf/EIHA-11-05-31_EIHA-Statement_on_THC_in_feed.pdf
Marijuana use among older adults in the U.S.A.: user characteristics, patterns of use, and implications for intervention (abst-2011) http://www.ncbi.nlm.nih.gov/pubmed/21108863
Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (abst-2011) http://www.ncbi.nlm.nih.gov/pubmed/21926420
The histopathology of drugs of abuse (abst–2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2559.2010.03728.x/abstract
125 Year Old Woman Claimed Smoking Cannabis Everyday Was Her Secret to Long Life (news-2011)
http://www.hanf-info.ch/info/en/125-Year-Old-Woman-Claimed-Smoking.html
Psychomotor Performance, Subjective and Physiological Effects and Whole Blood Δ9-Tetrahydrocannabinol Concentrations in Heavy, Chronic Cannabis Smokers Following Acute Smoked Cannabis (full–2012) http://jat.oxfordjournals.org/content/36/6/405.full
Prevalences of illicit drug use in people aged 50 years and over from two surveys (full–2012) http://ageing.oxfordjournals.org/content/41/4/553.long
Chronic Cannabis Abuse, Delta-9-tetrahydrocannabinol and Thyroid Function. (full – 2012) https/www.thieme-connect.com/ejournals/html/10.1055/s-0032-1316342
Acute effects of THC on time perception in frequent and infrequent cannabis users (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581701/
Functional connectivity in brain networks underlying cognitive control in chronic cannabis users (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376324/
Dopamine Response to Psychosocial Stress in Chronic Cannabis Users: A PET Study With [11C]-(+)-PHNO (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572464/
Assessing topographical orientation skills in cannabis users (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259701/?toolubmed
Evaluation of the safety and tolerability profile of Sativex: is it reassuring enough? (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22509986
Pot smoking not tied to middle-age mental decline (news–2012) http://www.mnn.com/health/fitness-well-being/stories/pot-smoking-not-tied-to-middle-age-mental-decline
One Joint a Week for 49 Years Doesn’t Harm Lungs, Research Finds (news–2012) http://www.businessweek.com/news/2012-01-13/one-joint-a-week-for-49-years-doesn-t-harm-lungsresearch-finds.html
Implicit Associations and Explicit Expectancies toward Cannabis in Heavy Cannabis Users and Controls (full–2013) http://www.frontiersin.org/Addictive_Disorders_and_Behavioral_Dyscontrol/10.3389/fpsyt.2013.00059/full
Single doses of THC and cocaine decrease proficiency of impulse control in heavy cannabis users (full–2013) http://onlinelibrary.wiley.com/doi/10.1111/bph.12425/full
Impact of prolonged cannabinoid excretion in chronic daily cannabis smokers’ blood on per se drugged driving laws (full–2013) http://www.clinchem.org/content/59/3/519.full?sid=c00c9727-29e8-493c-83b8-456467e158b9
Cannabis use: a perspective in relation to the proposed UK drug-driving legislation (full–2013) http://onlinelibrary.wiley.com/doi/10.1002/dta.1588/full
Effects of marijuana smoking on the lung (full–2013) http://www.atsjournals.org/doi/full/10.1513/AnnalsATS.201212-127FR#.U903xGN8E24
top
Creativity in cannabis-users and in drug addicts in maintenance treatment and in rehabilitation. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23359015
Health outcomes associated with long-term regular cannabis and tobacco smoking (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23501136
Marijuana’s dose-dependent effects in daily marijuana smokers. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23937597
Around-the-clock oral THC effects on sleep in male chronic daily cannabis smokers (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23952899
Cannabis Cue Reactivity and Craving Among Never, Infrequent and Heavy Cannabis Users. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24264815
Relationship between working-memory network function and substance use: a 3-year longitudinal fMRI study in heavy cannabis users and controls (abst–2013) http://onlinelibrary.wiley.com/doi/10.1111/adb.12111/abstract
Long-Term Cannabis Use Is Associated With Better Health Than Long-Term Tobacco use (news–2013) http://hempedification.blogspot.com/2013_04_01_archive.html
Marijuana habit not linked to lung cancer (news – 2013) http://www.clinicalpsychiatrynews.com/news/addiction-medicine/single-article/marijuana-habit-not-linkedto-lung-cancer/73840afd2cca226b9e6a9ddc7cb0d039.html
Marijuana has no adverse effects on health, BU study suggests (news–2013) http://dailyfreepress.com/2013/09/25/marijuana-has-no-adverse-effects-on-health-bu-study-suggests/
Study: Recreational Marijuana Users Show No ‘Negative Health Outcomes’ (news–2013) http://www.leafscience.com/2013/09/24/study-recreational-marijuana-users-show-negative-healthoutcomes/
No detectable association between frequency of marijuana use and health or healthcare utilization (news–2013) http://medicalxpress.com/news/2013-09-association-frequency-marijuana-health-healthcare.html
Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium (full–2014) http://onlinelibrary.wiley.com/doi/10.1002/ijc.29036/full
Therapeutic benefits of cannabis: a patient survey (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998228/
Relationship between working-memory network function and substance use: a 3-year longitudinal fMRI study in heavy cannabis users and controls (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24589297
Long-Term Effectiveness and Safety of Nabiximols (Tetrahydrocannabinol/Cannabidiol Oromucosal Spray) in Clinical Practice (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24943098
High-Intensity Cannabis Use and Adherence to Antiretroviral Therapy Among People Who Use Illicit Drugs in a Canadian Setting (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25012624
Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25135301
Couples’ Marijuana Use Is Inversely Related to Their Intimate Partner Violence Over the First 9 Years of Marriage (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25134048
Effects of Marijuana Exposure on Expiratory Airflow: A Study of Adults who Participated in the U.S. National Health and Nutrition Examination Study (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25521349
Marijuana Use Results in Less Domestic Violence (news-2014) http://blog.sfgate.com/smellthetruth/2014/08/19/marijuana-in-marriage-equals-less-violence-study-finds/
top
Cannabis conundrum: Evidence of harm?: Opposition to marijuana use is often rooted in arguments about the drug’s harm to children and adults, but the scientific evidence is seldom clear-cut (article-2015) http://onlinelibrary.wiley.com/doi/10.1002/cncy.21516/full
Daily marijuana use is not associated with brain morphometric measures in adolescents or adults (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25632127
The Impact Of Smoking Marijuana Regularly On Your Lungs, According To Science (news-2015) http://thinkprogress.org/health/2015/01/22/3614459/new-pot-research/
Effects of quitting cannabis on respiratory symptoms (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25837035
Responsible and controlled use: Older cannabis users and harm reduction (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25911027
Chronic Adolescent Marijuana Use as a Risk Factor for Physical and Mental Health Problems in Young Adult Men (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/26237286
Daily pot use not associated with brain shrinkage: Colorado study (news-2015) http://news.yahoo.com/daily-pot-not-associated-brain-shrinkage-colorado-study-235549441.html
What It’s Like To Smoke Pot Every Day For 50 Years (news-2015) https://www.yahoo.com/health/what-its-like-to-smoke-pot-every-day-for-50-years-117780070001.html


LUNG FUNCTION
Does cannabis use predispose to chronic airflow obstruction? (full–2010) http/erj.ersjournals.com/content/35/1/3.full?ijkey=d1405bb2fc0ed2aff675335858f284f7f470fbbc&keytype2=tf_ipsecsha
“Bong lung” in cystic fibrosis: a case report (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2998526/?toolmcentrez
Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis (full–2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2893662/
Effects of cannabis on lung function: a population-based cohort study (full–2010) http/erj.ersjournals.com/content/35/1/42.long
The histopathology of drugs of abuse (abst – 2011) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2559.2010.03728.x/abstract
Scripps Research Scientists Discover Inflammation Is Controlled Differently in Brain and Other Tissues (news – 2011) http/www.alphagalileo.org/ViewItem.aspx?ItemId=113766&CultureCode=en
Association Between Marijuana Exposure and Pulmonary Function Over 20 Years (full – 2012) http/jama.jamanetwork.com/article.aspx?articleid=1104848
Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: Role for the adenosine A(2A) receptor. (full – 2012) http/www.sciencedirect.com/science/article/pii/S0014299912000052
Cannabidiol (CBD) enhances lipopolysaccharide (LPS)-induced pulmonary inflammation in C57BL/6 mice. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3632657/
Marijuana doesn’t harm lung function, study found (news – 2012) http/news.yahoo.com/marijuana-doesnt-harm-lung-function-study-found-210146886.html
Study: Smoking Marijuana Not Linked with Lung Damage (news – 2012) http/healthland.time.com/2012/01/10/study-smoking-marijuana-not-linked-with-lung-damage/
Marijuana Smoke Not as Damaging as Tobacco, Says Study (news – 2012) http/news.yahoo.com/marijuana-smoke-not-damaging-tobacco-says-study-204709671–abc-news.html
top
One Joint a Week for 49 Years Doesn’t Harm Lungs, Research Finds (news – 2012) http/www.businessweek.com/news/2012-01-13/one-joint-a-week-for-49-years-doesn-t-harm-lungsresearch-finds.html
Occasional marijuana use ‘boosts lungs’ (news – 2012) http/www.heraldsun.com.au/news/breaking-news/occasional-marijuana-use-boosts-lungs/story-e6frf7jx-1226241475448
Pot smokers don’t puff away lung health: study (news – 2012) http/www.reuters.com/article/2012/01/11/us-pot-health-idUSTRE8092BC20120111
Science Says: Lungs Love Weed (news – 2012) http/www.takepart.com/article/2012/01/11/marijuana-not-bad-your-lungs
Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3808422/
High Times, Low Sats: Diffuse Pulmonary Infiltrates Associated with Chronic Synthetic Cannabinoid Use. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3657026/
Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. (full– 2013) http/www.pnas.org/content/110/46/18710.full?sid=b685d344-5523-4371-a682-b03610d573e6
Effects of marijuana smoking on the lung. (full – 2013) http/www.atsjournals.org/doi/full/10.1513/AnnalsATS.201212-127FR#.U903xGN8E24
Cannabis and the Lung: No More Smoking Gun? (editorial – 2013) http/www.atsjournals.org/doi/abs/10.1513/AnnalsATS.201302-034ED?url_ver=Z39.88-2003&rfr_idri:rid:crossref.org&rfr_dat=cr_pub%3dpubmed&
The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23428645
Protective effect of magnolol on lipopolysaccharide-induced acute lung injury in mice. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23053725
Health outcomes associated with long-term regular cannabis and tobacco smoking. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23501136
Synthetic Marijuana: Possibly A Lung’s Dying Breath. (abst – 2013) http/journal.publications.chestnet.org/article.aspx?articleid=1740537
Synthetic Cannabinoids as a Cause for Black Carbonaceous Bronchoalveolar Lavage. (abst – 2013) http/journal.publications.chestnet.org/article.aspx?articleid=1740090
Study: Cannabinoids Offer Treatment For Severe Lung Disease (news – 2013) http/www.leafscience.com/2013/11/21/study-cannabinoids-offer-treatment-severe-lung-disease/
Marijuana Smoking Not Linked to Chronic Breathing Problems (news – 2014) http/www.webmd.com/lung/news/20120103/marijuana-smoking-not-linked_to-chronic-breathingproblems
CB2 Receptor Activation Ameliorates the Proinflammatory Activity in Acute Lung Injury Induced by Paraquat (full-2014) http/www.hindawi.com/journals/bmri/2014/971750/
Does cannabis smoking predispose to lung bulla formation? (full-2014) http/aan.sagepub.com/content/22/1/65.long
Cardiorespiratory Anomalies in Mice Lacking CB1 Cannabinoid Receptors (full-2014) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100536
Effect of melilotus extract on lung injury by upregulating the expression of cannabinoid CB2 receptors in septic rats (full-2014) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3995869/
Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1 receptors (abst-2014) http/www.ncbi.nlm.nih.gov/pubmed/24467410
top
Cannabidiol improves lung function and inflammation in mice submitted to LPS-induced acute lung injury (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25356537
Δ9 Tetrahydrocannabinol attenuates Staphylococcal enterotoxin B-induced inflammatory lung injury and prevents mortality in mice by modulation of miR-17-92 cluster and induction of T-regulatory cells (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25425209
Pulmonary Effects of Synthetic Marijuana: Chest Radiography and CT Findings (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25541904
Cannabis, tobacco smoking, and lung function: a cross-sectional observational study in a general practice population (full-2015) http://bjgp.org/content/65/631/e89
Synthetic cannabinoids as a cause for black carbonaceous bronchoalveolar lavage (full-2015) http://casereports.bmj.com/content/2015/bcr-2015-211391.full.pdf
Cannabis conundrum: Evidence of harm?: Opposition to marijuana use is often rooted in arguments about the drug’s harm to children and adults, but the scientific evidence is seldom clear-cut (article-2015) http://onlinelibrary.wiley.com/doi/10.1002/cncy.21516/full
The effect of phytocannabinoids on airway hyper-responsiveness, airway inflammation, and cough (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25655949
Δ9 Tetrahydrocannabinol attenuates Staphylococcal enterotoxin B-induced inflammatory lung injury and prevents mortality in mice by modulation of miR-17-92 cluster and induction of T-regulatory cells (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25425209
Effects of quitting cannabis on respiratory symptoms (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25837035
Endogenous 2-Arachidonoylglycerol Alleviates Cyclooxygenases-2 Elevation-Mediated Neuronal Injury from SO2 Inhalation via PPARγ Pathway. (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/26209559
A New Threat: Synthetic Marijuana Associated Lung Disease (abst-2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4684
Dabble With Danger: A Case Of Severe Respiratory Failure Following Inhalation Of Butane Hash Oil (abst-2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4596
Acute Eosinophilic Pneumonia With Respiratory Failure Induced By ‘Bonzai’ (Synthetic Cannabinoid) Inhalation (abst-2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1496
Peripheral Targeting of CB1 Cannabinoid Receptors Protects from Radiation-Induced Pulmonary Fibrosis (abst-2015) http://www.atsjournals.org/doi/abs/10.1165/rcmb.2014-0331OC#.VcgfrvlwtB8
The Impact Of Smoking Marijuana Regularly On Your Lungs, According To Science (news-2015) http://thinkprogress.org/health/2015/01/22/3614459/new-pot-research/
UCLA Professor Finds Marijuana Is Safer to Smoke Than Tobacco (news-2015) http://www.laweekly.com/music/ucla-professor-finds-marijuana-is-safer-to-smoke-than-tobacco-5658317


LUPUS ERYTHEMATOSUS
Systemic Lupus Erythematosus by Lisa Swiderski (anecdotal–undated) http://rxmarijuana.com/lupus.htm
Lupus by Randi Cox (anecdotal–undated) http://rxmarijuana.com/shared_comments/lupus2.htm
Cannabis May Suppress Immune System (news–2003) http://lupus.webmd.com/news/20030415/cannabis-may-suppress-immune-system
Systemic Lupus by Dawn (anecdotal–2005) http://www.erowid.org/experiences/exp.php?ID=49481
top
Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid (abst-2008) http://www.ncbi.nlm.nih.gov/pubmed/18040689
Study uncovers marijuana’s potential to treat autoimmune diseases (news–2014) http://www.news-medical.net/news/20140603/Study-uncovers-marijuanas-potential-to-treat-autoimmunediseases.aspx
How Cannabis Helps Lupus (news–2015) http://www.theecdf.org/lupus/
One family’s medical-marijuana story (news–2015) http://www.philly.com/philly/news/20150624_One_family_s_medical-marijuana_story.html


LYME DISEASE 
Cannabis Alleviates Symptoms of Lyme Disease! (news–2010) http://ezinearticles.com/?Cannabis-Alleviates-Symptoms-of-Lyme-Disease!&id=4979819
Medical Marijuana and Lyme Disease…Alexis’ story (news/anecdotal–2012) http://www.doobons.com/blog/2012/02/22/medical-marijuana-and-lyme-disease-alexis-story/
This for That: Lyme Disease (news/anecdotal–2012) http://the420times.com/2012/01/this-for-that-lyme-disease/
How Cannabis Helps Lyme Disease (news–2014) http://www.theecdf.org/lyme-disease/
Cannabis kicks Lyme disease to the curb (news–2014) http://www.naturalnews.com/043834_cannabis_Lyme_disease_medical_marijuana.html
Cannabidiol paste potentially a cure for Lyme disease (news–2015) http://www.bclocalnews.com/news/301163011.html
top


Advertisements