I-L (Pre-2000)

IBUPROFEN
IMMUNE SYSTEM
INDICATIONS AND CLINICAL USES
INTERACTIONS WITH OTHER DRUGS
IQ / MEMORY / COGNITIVE EFFECTS
KNOCK-OUT MICE (Examples of Severely Defective Endocannabinoid Systems)
LIVER DISEASE – NON HEPATITIS (See Also HEPATITIS)
LONG TERM USE EFFECTS
LUNG FUNCTION
LUPUS


IBUPROFEN
Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship (full–1997) http://jpet.aspetjournals.org/content/283/2/729.long
Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide (abst–1997) http://www.ncbi.nlm.nih.gov/pubmed/9060042
Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen (abst–1999) http://www.ncbi.nlm.nih.gov/pubmed/9989926


IMMUNE SYSTEM
Cannabinoids enhance human B-cell growth at low nanomolar concentrations (full–1995) http://ac.els-cdn.com/001457939500746V/1-s2.0-001457939500746V-main.pdf?_tid=84cf5e30-1b93-11e5-b97a-00000aacb362&acdnat=1435275790_97d5fbd61b42513c58283075bc4c0918
Presence and functional regulation of cannabinoid receptors in immune cells (abst–1999) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=10462064&dopt=abstractplus
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INDICATIONS AND CLINICAL USES
HEMP AS A MEDICAMENT : Survey of clinical experiences (full-1955) http://www.bushka.cz/KabelikEN/survey.html
Cannabis as a Medicine? (editorial-1995) http://bja.oxfordjournals.org/cgi/reprint/74/4/359?maxtoshow=&hits=80&RESULTFORMAT=1&andorexacttitle=and&andorexacttitleabs=and&fulltext=cannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT
Medicinal Applications of Delta-9-Tetrahydrocannabinol and Marijuana (abst-1997) http://annals.org/article.aspx?articleid=710533
Hemp and Health (book-1999) http://www.rexresearch.com/hhusb/hmphlth.htm#hhl2s


INTERACTIONS WITH OTHER DRUGS
INTERACTIONS OF Δ1-TETRAHYDROCANNABINOL WITH BARBITURATES AND METHAMPHETAMINE (abst-1970) http://jpet.aspetjournals.org/content/173/1/94.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=2560&resourcetype=HWCIT
Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism (full-1972) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666020/
Proceedings: Effects of chronic and acute cannabis treatment upon thiopentone anaesthesia in rabbits (full-1972) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666093/?tool=pubmed
Cardiovascular and respiratory effects of cannabis extracts and 1-tetra-hydrocannabinol (1-THC) (abst-1973) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1776288/pdf/brjpharm00549-0201a.pdf
Interaction of cannabis and general anaesthetic agents in mice (full-1974) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1776719/?tool=pmcentrez
Cannabidiol interferes with the effects of Δ9-tetrahydrocannabinol in man (abst–1974) http://www.sciencedirect.com/science/article/pii/0014299974901290
Combination of delta9-tetrahydrocannabinol with oxymorphone or pentobarbital: Effects on ventilatory control and cardiovascular dynamics (link to PDF-1975) http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1961848
Interactions in man of delta-9-tetrahydrocannabinol. II. Cannabinol and cannabidiol (abst–1975) http://www.ncbi.nlm.nih.gov/pubmed/1097148
The analgesic properties of delta-9-tetrahydrocannabinol and codeine (abst-1975) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=17
Effects of marihuana combined with secobarbital (abst–1975) http://www.ncbi.nlm.nih.gov/pubmed/1100299
The Effects of Delta-9-Tetrahydrocannabinol (Cannabis) on Cardiac Performance with and without Beta Blockade (full-1976) http://circ.ahajournals.org/cgi/reprint/53/4/703?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=2080&resourcetype=HWCIT
Effects of marihuana-dextroamphetamine combination (abst–1976) http://www.ncbi.nlm.nih.gov/pubmed/782773
Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats (full-1977) http://jpet.aspetjournals.org/content/201/1/26.abstract?ijkey=8457ace5313942358e64d156c12d04bd3c7d5f21&keytype2=tf_ipsecsha
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The effect of delta 9-tetrahydrocannabinol, cannabidiol, and cannabinol on the anaesthesia induced by various anaesthetic agents in mice (abst-1977) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=414255&dopt=abstractplus
Propranolol Effects on Acute Marihuana Intoxication in Man (abst–1977) http://www.ncbi.nlm.nih.gov/pubmed/403557
Enhanced Biotransformation of Theophylline in Marihuana and Tobacco Smokers (abst–1978) http://www.ncbi.nlm.nih.gov/pubmed/688731
Effects of drugs on behavior in pigeons tolerant to delta 9-tetrahydrocannabinol (abst-1980) http://jpet.aspetjournals.org/content/212/1/85.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT.
Tetrahydrocannabinol potentiates reserpine-induced hypokinesia (abst–1981) http://www.ncbi.nlm.nih.gov/pubmed/6273940
Adverse Interaction Between Disulfiram and Marijuana: a Case Report (abst–1983) http://www.ncbi.nlm.nih.gov/pubmed/6295192
ANALGESIC INTERACTION BETWEEN NITROUS OXIDE AND DELTA-9-TETRAHYDEROCANNABINOL IN THE RAT (abst-1983) http://bja.oxfordjournals.org/cgi/content/abstract/55/10/997?maxtoshow=&hits=80&RESULTFORMAT=1&andorexacttitle=and&andorexacttitleabs=and&fulltext=cannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT
Respiratory effects of cocaine “freebasing” among habitual users of marijuana with or without tobacco (full-1987) http://journal.publications.chestnet.org/data/Journals/CHEST/21568/638.pdf
Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy induced nausea and vomiting (abst-1991) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=28
Flashback Following Use of Cannabis–a Review (abst–1991) http://www.ncbi.nlm.nih.gov/pubmed/1761271
Marihuana attenuates the rise in plasma ethanol levels in human subjects (abst–1992) http://www.ncbi.nlm.nih.gov/pubmed/1326277
Marihuana smoking increases plasma cocaine levels and subjective reports of euphoria in male volunteers (abst–1994) http://www.ncbi.nlm.nih.gov/pubmed/7938127
Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin (abst-1995) http://ajpheart.physiology.org/cgi/content/abstract/269/6/H1859?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=2320&resourcetype=HWCIT
Marijuana and chocolate (abst–1996) http://cacao-chocolate.com/choc-cannabis.html
Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide (abst–1997) http://www.ncbi.nlm.nih.gov/pubmed/9060042
Case report: adverse effects of taking tricyclic antidepressants and smoking marijuana (full-1999) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2328650/?tool=pmcentrez&page=1


IQ / MEMORY / COGNITIVE EFFECTS
Marihuana and Memory: Acquisition or Retrieval? (abst-1971) http://www.sciencemag.org/cgi/content/abstract/173/4001/1038?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
The Report of the National Commission on Marihuana and Drug Abuse Acute Effects of Marihuana (full–1972) http://www.druglibrary.org/schaffer/library/studies/nc/nc1e.htm
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Neuropsychological effects of marijuana (full-1973) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1941135&tool=pmcentrez
Marihuana Use and Psychosocial Adaptation (abst-1974) http://archpsyc.amaassn.org/cgi/content/abstract/31/5/713?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Operant acquisition of marihuana in man (abst-1976) http://www.ncbi.nlm.nih.gov/pubmed/933012
Cognition and Long-Term Use of Ganja (Cannabis) (full-1981) http://www.druglibrary.org/schaffer/hemp/medical/cognition.htm
Operant acquisition of marihuana by women (abst-1985) http://www.ncbi.nlm.nih.gov/pubmed/2995644
Flashback Following Use of Cannabis-a Review (abst–1991) http://www.ncbi.nlm.nih.gov/pubmed/1761271
THREE THINGS MARIJUANA DOESN’T DO (news-1992) http://www.ukcia.org/research/mjfaq2.php
60- and 72-month follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol: cognitive and language assessment (abst–1992) http://www.ncbi.nlm.nih.gov/pubmed/1469105
Cerebellar activity and disturbed time sense after THC (abst-1998) http://www.ncbi.nlm.nih.gov/pubmed/9666122
Cannabis use and cognitive decline in persons under 65 years of age (full-1999) http://www.ukcia.org/research/CannabisUseAndCognitiveDecline.html
Learning impairment produced in rats by the cannabinoid agonist HU 210 in a watermaze task (abst–1999) http://www.ncbi.nlm.nih.gov/pubmed/10548271
Enhancement of Memory in Cannabinoid Cb1 Receptor Knock-out Mice (abst-1999) http://www.ncbi.nlm.nih.gov/pubmed/10499380


KNOCK-OUT MICE
Increased Mortality, Hypoactivity, and Hypoalgesia in Cannabinoid Cb1 Receptor Knockout Mice (full–1999) http://www.pnas.org/content/96/10/5780.long
Enhancement of Memory in Cannabinoid Cb1 Receptor Knock-out Mice (abst-1999) http://www.ncbi.nlm.nih.gov/pubmed/10499380


LIVER DISEASE – NON HEPATITIS
HEMP AS A MEDICAMENT : Importance of hemp seeds in the tuberculosis therapy (Forum thread-full-1955) (EDEZYME.recipe) http://www.bushka.cz/KabelikEN/hempseed.html


LONG TERM USE EFFECTS
Ganja in Jamaica: The Effects of Marijuana Use (book exerpts-1976) http://csp.org/chrestomathy/ganja_in.html
Physical assessment of 30 chronic cannabis users and 30 matched controls (1st page-1976) http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1976.tb49895.x/abstract
Cognition and Long-Term Use of Ganja (Cannabis) (full-1981) http://www.druglibrary.org/schaffer/hemp/medical/cognition.htm
Neurological and neuroradiological examination of chronic cannabis smokers (abst-1983) http://www.ncbi.nlm.nih.gov/pubmed/6830182
Long-Term Marijuana Users Suffer Few Health Problems, Australian Study Indicates (news-1997) http://www.ukcia.org/research/aus.htm
Regular Marijuana Users Have No Higher Rates of Mortality, Long-Term Study Concludes (news-1997) http://norml.org/news/1997/05/15/regular-marijuana-users-have-no-higher-rates-of-mortality-long-termstudy-concludes
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Long-term cannabis use: characteristics of users in an Australian rural area (abst-1998) http://www.ncbi.nlm.nih.gov/pubmed/9744119
Immunology in medical practice. XIV. Central nervous system complications in systemic autoimmune diseases (abst-1998) http://www.ncbi.nlm.nih.gov/pubmed/9623096


LUNG FUNCTION
Byssinosis, Chronic Bronchitis, and Ventilatory Capacities in Workers Exposed to Soft Hemp Dust (full-1968) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1008770&tool=pmcentrez
Respiratory mechanics and dust exposure in byssinosis (full–1970) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC322449/
Cardiovascular and respiratory effects of cannabis in cat and rat (full–1973) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1776461/
Intravenous delta9-Tetrahydrocannabinol: Effects of ventilatory control and cardiovascular dynamics (link to PDF-1975) http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1961833
Physical assessment of 30 chronic cannabis users and 30 matched controls (abst-1976) http://www.ncbi.nlm.nih.gov/pubmed/1071376
Bronchodilator effect of delta1-tetrahydrocannabinol (full-1978) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1429361/
Acute Effects of Marihuana Smoking on Maximal Exercise Performance (abst–1986) http://www.ncbi.nlm.nih.gov/pubmed/3097453
No increase in carcinogen-DNA adducts in the lungs of monkeys exposed chronically to marijuana smoke (abst-1992) http://www.ncbi.nlm.nih.gov/pubmed/1488780
Health care use by frequent marijuana smokers who do not smoke tobacco (full-1993) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1311782/?tool=pmcentrez


LUPUS
Immunology in medical practice. XIV. Central nervous system complications in systemic autoimmune diseases (abst-1998) http://www.ncbi.nlm.nih.gov/pubmed/9623096
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