D-E (Pre-2000)

DEPRESSION
DERMATITIS
DRIVING AND CANNABIS
DRUG TESTING
DRUG TESTING – BLOOD
DRUG TESTING – HAIR
DRUG TESTING – FINGERNAILS
DRUG TESTING – URINE
DYSKINESIA
DYSTONIA
EDEMA
ENCEPHALOMYELITIS / EAE (A Mouse Multiple Sclerosis Model)
ENDOCANNABINOIDS (See Also ANANDAMIDE, 2-AG)
ENDOCANNABINOID SYSTEM (See Also CBR‘s, ENDOCANNABINOIDS, 2-AG, ANANDAMIDE)
ENTOURAGE EFFECT – ENDOCANNABINOIDS
EPILEPSY / SEIZURES
EXERCISE and the ENDOCANNABINOID SYSTEM


DEPRESSION
The perceived effects of smoked cannabis on patients with multiple sclerosis (abst-1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13


DERMATITIS
Allergenic properties of naturally occurring cannabinoids (abst-1983) http://www.ncbi.nlm.nih.gov/pubmed/6620158
Hemp Seed Oil : The Wonder Oil For the New Millennium (full-1999) http://www.ukcia.org/research/Happi/HempSeedOilTheWonderOilForTheNewMillennium.htm


DRIVING AND CANNABIS
Comparison of the Effects of Marijuana and Alcohol on Simulated Driving Performance (full-1969) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s4_4.pdf
Simulated Flying Performance After Marihuana Intoxication (abst–1976) http://www.ncbi.nlm.nih.gov/pubmed/1252201
Marijuana effects on simulated flying ability (abst–1976) http://www.ncbi.nlm.nih.gov/pubmed/1267035
Abstracts of several studies (absts-1982-1998) http://www.ukcia.org/research/medline/8.htm
EFFECTS OF MARIJUANA ON HUMAN REACTION TIME AND MOTOR CONTROL (full–1977) http://www.amsciepub.com/doi/abs/10.2466/pms.1977.45.3.935?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&
Marijuana And Actual Driving Performance (full-1993) http://ntl.bts.gov/lib/25000/25800/25867/DOT-HS-808-078.pdf
CANNABIS AND ROAD SAFETY: AN OUTLINE OF THE RESEARCH STUDIES TO EXAMINE THE EFFECTS OF CANNABIS ON DRIVING SKILLS AND ON ACTUAL DRIVING PERFORMANCE (full-c.1995) http://www.ukcia.org/research/driving2.htm
Cannabis and driving (abst-1998) http://www.ukcia.org/research/driving4.html
University Of Toronto Study Shows Marijuana Not A Factor In Driving Accidents (news-1999) http://www.sciencedaily.com/releases/1999/03/990325110700.htm
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DRUG TESTING
THE SPECTROPHOTOMETRIC DETECTION OF CANNABIS SATIVA RESIN (1st page–1953) http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1953.tb13950.x/abstract
Pharmacological activity of three fractions obtained by smoking cannabis through a water pipe (abst–1976) http://www.ncbi.nlm.nih.gov/pubmed/1048934
Legal and ethical aspects of drug testing (full-1989) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807765/?tool=pmcentrez&page=1
Interference of Common Household Chemicals in Immunoassay Methods for Drugs of Abuse (full-1989) http://www.clinchem.org/cgi/reprint/35/4/648?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cann
abinoid&searchid=1&FIRSTINDEX=1440&resourcetype=HWCIT
Test Negative A look at the “evidence” justifying illicit-drug tests (news–1990) http://druglibrary.org/schaffer/MISC/testneg.htm
Report on the Utah Power and Light Company and the Georgia Power Company Studies (news–1990) http://www.ukcia.org/research/utah.php
Passive inhalation of cannabis smoke: a novel defence strategy? (abst-1996) http://www.ncbi.nlm.nih.gov/pubmed/15335617


DRUG TESTING – BLOOD
Delta-9-tetrahydrocannabinol: Metabolism and Disposition in Long-term Marihuana Smokers (abst–1971) http://www.ncbi.nlm.nih.gov/pubmed/5087483
Stability of delta 9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC in blood and plasma (full–1984) http://jat.oxfordjournals.org/content/8/5/202.long
Tetrahydrocannabinol stability in whole blood: plastic versus glass containers (full–1986) http://jat.oxfordjournals.org/content/10/4/129.long
Characterization of the absorption phase of marijuana smoking (abst–1992) http://www.ncbi.nlm.nih.gov/pubmed/1320536


DRUG TESTING – HAIR
Testing human hair for cannabis (abst-1995) http://www.ncbi.nlm.nih.gov/pubmed/7860029
Drugs in Prehistory: Chemical Analysis of Ancient Human Hair (full–1998) http://www.researchgate.net/publication/12579718_Drugs_in_prehistory_chemical_analysis_of_ancient_human_hair
Are cannabinoids detected in hair after washing with Cannabio shampoo? (full-1999) http://jat.oxfordjournals.org/content/23/5/349.long


DRUG TESTING – FINGERNAILS
Nail analysis for drugs of abuse: extraction and determination of cannabis in fingernails by RIA and GC-MS (full–1999) http://jat.oxfordjournals.org/content/23/3/147.long
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DRUG TESTING – URINE
Delta-9-tetrahydrocannabinol: Metabolism and Disposition in Long-term Marihuana Smokers (abst–1971) http://www.ncbi.nlm.nih.gov/pubmed/5087483
Confirmation of the Presence of 11-Hydroxy-r 9-Tetrahydrocannabinol in the Urine of Marijuana Smokers (full-1972) http://ajph.aphapublications.org/cgi/reprint/62/10/1394?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT
Detection of cannabis products in urine by radioimmunoassay (full-1975) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1673774/?tool=pmcentrez&page=1
Homogeneous enzyme immunoassay for cannabinoids in urine (full-1978) http://www.clinchem.org/cgi/reprint/24/1/95
Laboratory verification of “heavy” and “light” users of cannabis (abst-1981) http://www.ncbi.nlm.nih.gov/pubmed/6267648
Persistence of Urinary Marijuana Levels After Supervised Abstinence (abst–1982) http://www.ncbi.nlm.nih.gov/pubmed/6287871
Passive inhalation of marihuana smoke and urinary excretion of cannabinoids (abst-1983) http://www.ncbi.nlm.nih.gov/pubmed/6305545
Excretion patterns of cannabinoid metabolites after last use in a group of chronic users (full-1985) http://www.nature.com/clpt/journal/v38/n5/pdf/clpt1985226a.pdf
Contact highs and urinary cannabinoid excretion after passive exposure to marijuana smoke (abst-1986) http://www.ncbi.nlm.nih.gov/pubmed/3017628
Cannabinoid intake by passive smoking (abst-1987) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=3551865&dopt=abstractplus
Marijuana-Laced Brownies: Behavioral Effects, Physiologic Effects, and Urinalysis in Humans Following Ingestion (full–1988) http://jat.oxfordjournals.org/content/12/4/169.long
False negative GC/MS assay for carboxy THC due to ibuprofen interference (full–1988) http://jat.oxfordjournals.org/content/12/5/290.long
Cross-reactivity of selected compounds in the Abbott TDx cannabinoid assay (full–1990) http://jat.oxfordjournals.org/content/14/5/277.long
SIMPLE WAY TO BEAT URINE TESTS — JUST DRINK WATER (news–1990) http://druglibrary.org/schaffer/MISC/drinkwater.htm
High urinary cannabinoids from a hashish body packer (full–1993) http://jat.oxfordjournals.org/content/17/7/439.long
Effect of freezing on the concentration of drugs of abuse in urine (full-1993) http://jat.oxfordjournals.org/content/17/6/378.long
Increased detection of marijuana use with a 50 micrograms/L urine screening cutoff (full-1994) http://www.clinchem.org/cgi/reprint/40/11/2114
Hemp oil ingestion causes positive urine tests for Δ9-tetrahydrocannabinol carboxylic acid (full-1997) http://www.druglibrary.org/crl/drugtesting/Constantino%20et.al%2097%20Hemp%20Oil%20JAnToxicol.pdf
A procedure to overcome interferences caused by the adulterant “Klear” in the GC-MS analysis of 11-nor-delta9-THC-9-COOH (full–1997) http://jat.oxfordjournals.org/content/21/3/240.long
Excretion of Cannabinoids in Urine After Ingestion of Cannabis Seed Oil (full–1997) http://jat.oxfordjournals.org/content/21/5/373.long
Marijuana-positive urine test results from consumption of hemp seeds in food products (full–1997) http://jat.oxfordjournals.org/content/21/6/476.long
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In vivo adulteration: excess fluid ingestion causes false-negative marijuana and cocaine urine test results (full–1998) http://jat.oxfordjournals.org/content/22/6/460.long
Urinary excretion profiles of 11-nor-9-carboxy-delta9-tetrahydrocannabinol: a delta9-THCCOOH to creatinine ratio study (full–1999) http://jat.oxfordjournals.org/content/23/6/531.long
Adulteration of urine by “Urine Luck” (full–1999) http://www.clinchem.org/cgi/content/full/45/7/1051
Potassium nitrite reaction with 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in urine in relation to the drug screening analysis (abst-1999) http://www.ncbi.nlm.nih.gov/pubmed/10486947?ordinalpos=102&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Concentration of Marijuana Metabolites in the Urine After Ingestion of Hemp Seed Tea (abst-1999) http://www.ncbi.nlm.nih.gov/pubmed/10390703


DYSKINESIA
Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced dystonic dyskinesia (abst-1985) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=142
The effects of the cannabinoid receptor agonist nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson’s disease (PD) (abst-1998) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=153


DYSTONIA
Tetrahydrocannabinol potentiates reserpine-induced hypokinesia (abst–1981) http://www.ncbi.nlm.nih.gov/pubmed/6273940
Treatment of Meige’s syndrome with cannabidiol (abst-1984) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=114
Open label evaluation of cannabidiol in dystonic movement disorders (full-1986) http://web.acsalaska.net/~warmgun/es017.html
Cannabidiol (CBD) in dystonic movement disorders (abst-1986) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=139
(+)-WIN 55,212-2, a novel cannabinoid receptor agonist, exerts antidystonic effects in mutant dystonic hamsters (abst 994) http://www.ncbi.nlm.nih.gov/pubmed/7698178
Cannabis in movement disorders (abst-1999) http://www.ncbi.nlm.nih.gov/pubmed/10627163


EDEMA
ANTI-EDEMA AND ANALGESIC PROPERTIES OF Δ9-TETRAHYDROCANNABINOL (THC) (abst-1973) http://jpet.aspetjournals.org/content/186/3/646.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=2160&resourcetype=HWCIT


ENCEPHALOMYELITIS / EAE
Suppression of experimental autoimmune encephalomyelitis by cannabinoids (abst–1997) http://www.ncbi.nlm.nih.gov/pubmed/7852052
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ENDOCANNABINOIDS
Cannabinoids (encyclopedia entry) http://www.chemie.de/lexikon/e/Cannabinoids/
Phytocannabinoids (news–undated) http://www.news-medical.net/health/Phytocannabinoids.aspx
Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand (full–1997) http://www.druglibrary.org/crl/receptors/endogenous/Goparahu%20et.al%2098%202-AG_%20FEBSLet.pdf
Brain Chemicals Mimic Marijuana (news-1997) http://www.ukcia.org/research/anandami.php
Body’s ‘cannabis’ could hold blood pressure key (news-1998) http://www.ukcia.org/research/blood-pressure.php
Cannabis and cannabinoids: pharmacology and rationale for clinical use (abst–1999) http://www.ncbi.nlm.nih.gov/pubmed/10575283
UC Irvine Researchers Demonstrate How Marijuana-Like Chemicals Work In The Brain (news-1999) http://www.sciencedaily.com/releases/1999/03/990323050735.htm


ENDOCANNABINOID SYSTEM
Cannabinoids (encyclopedia entry) http://www.chemie.de/lexikon/e/Cannabinoids/
Cannabinoid Receptor Ligands (full-undated) http://www.tocris.com/pdfs/cannabinoid_receptor_review/page_001.html
Cellular effects of cannabinoids (abst-1986) http://pharmrev.aspetjournals.org/content/38/1/45.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Cannabinoid Receptor Localization in Brain (full-1990) http://www.pnas.org/content/87/5/1932.full.pdf+html?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT
Molecular cloning of a human cannabinoid receptor which is also expressed in testis (full–1991) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1151556/
Characterization and Localization of Cannabinoid Receptors in Rat Brain: A Quantitative in vitro Autoradiographic Study (full–1991) http://www.jneurosci.org/content/11/2/563.long
Loss of cannabinoid receptors in the substantia nigra in Huntington’s disease (abst–1993) http://www.ncbi.nlm.nih.gov/pubmed/8255419
Molecular characterization of a peripheral receptor for cannabinoids (abst–1993) http://www.ncbi.nlm.nih.gov/pubmed/7689702
Molecular Aspects of Cannabinoid Receptors (abst–1997) http://dl.begellhouse.com/journals/7b004699754c9fe6,0af6f0a055729f1f,27123f036bd79f8c.html
Brain Chemicals Mimic Marijuana (news-1997) http://www.ukcia.org/research/anandami.php
Changes in cannabinoid receptor binding and mRNA levels in several brain regions of aged rats (full–1998) http://www.sciencedirect.com/science/article/pii/S0925443998000428
Body’s ‘cannabis’ could hold blood pressure key (news-1998) http://www.ukcia.org/research/blood-pressure.php
Pain modulation by release of the endogenous cannabinoid anandamide (full-1999) http://www.pnas.org/content/96/21/12198.full
Cannabis and cannabinoids: pharmacology and rationale for clinical use (abst–1999) http://www.ncbi.nlm.nih.gov/pubmed/10575283
Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response (abst–1999) http://www.ncbi.nlm.nih.gov/pubmed/10392859
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Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors (abst–1999) http://link.springer.com/article/10.1007%2Fs002130050953
Links found between marijuana and vision (news–1999) http://archives.cnn.com/1999/HEALTH/12/07/science.marijuana/index.html
Why your brain is primed for a high (news-1999) http://www.mapinc.org/drugnews/v99.n362.a08.html


ENTOURAGE EFFECT – ENDOCANNABINOIDS
An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity (abst–1998) http://www.ncbi.nlm.nih.gov/pubmed/9721036


EPILEPSY / SEIZURES
Marijuana and Epilepsy (anecdotal-undated) http://www.rxmarihuana.com/epilepsy.htm
Anti-epileptic Action of Marijuana-Active Substances (full-1949) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s3_6.pdf
Anticonvulsant nature of marihuana smoking (abst-1975) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=39
Antiepileptic and prophylactic effects of tetrahydrocannabinols in amygdaloid kindled cats (abst–1975) http://www.ncbi.nlm.nih.gov/pubmed/1183427
Anticonvulsant activity of four oxygenated cannabidiol derivatives (abst–1975) http://www.ncbi.nlm.nih.gov/pubmed/1188178
Epileptiform seizures in domestic fowl. V. The anticonvulsant activity of delta9-tetrahydrocannabinol (abst–1975) http://www.ncbi.nlm.nih.gov/pubmed/1222370
Anticonvulsant activity of delta9-tetrahydrocannabinol compared with three other drugs (abst–1976) http://www.ncbi.nlm.nih.gov/pubmed/1253828
Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats (full-1977) http://jpet.aspetjournals.org/content/201/1/26.abstract?ijkey=8457ace5313942358e64d156c12d04bd3c7d5f21&keytype2=tf_ipsecsha
Anticonvulsant Action of Cannabis in the Rat: Role of Brain Monoamines (abst–1978) http://www.ncbi.nlm.nih.gov/pubmed/104333
Chronic administration of cannabidiol to healthy volunteers and epileptic patients (abst-1980) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=42
Antiepileptic potential of cannabidiol analogs (abst-1981) http://www.ncbi.nlm.nih.gov/pubmed/7298873
The cannabinoids as potential antiepileptics (abst-1981) http://www.ncbi.nlm.nih.gov/pubmed/6975285
Hypnotic and Antiepileptic Effects of Cannabidiol (abst-1981) http://www.ncbi.nlm.nih.gov/pubmed/7028792
Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs (abst-1982) http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=7071126&dopt=abstractplus
Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice (abst-1982) http://www.ncbi.nlm.nih.gov/pubmed/6129147
ILLICIT DRUG USE AND THE RISK OF NEW-ONSET SEIZURES (abst–1990) http://aje.oxfordjournals.org/content/132/1/47.abstract?sid=9fd403c4-2e6e-4df4-a57c-208434b8ad0a
Marijuana use and the risk of new onset seizures (full-1992) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376682/?tool=pmcentrez


EXERCISE and the ENDOCANNABINOID SYSTEM
Acute Effects of Marihuana Smoking on Maximal Exercise Performance (abst–1986) http://www.ncbi.nlm.nih.gov/pubmed/3097453
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