O (2010-2017)

STUDIES ON CONDITIONS and RELATED ARTICLES 2010-2017

+Studies in 2000-2009 List
*Studies in Pre-2000 List

OBESITY/ADIPOSE TISSUE*+
OBSESSIVE COMPULSIVE DISORDER/OCD +
OLDER ADULTS +
OMEGA-3/CB1 CONNECTION*+ (Docosahexaenoic acid (DHA), α-Linolenic acid (ALA), Eicosapentaenoic acid (EPA) – Without Omega 3, new CB1 receptors are made imperfectly. Hemp seed, flax seed, walnut and canola oils have ALA and EPA in them. Wild-caught salmon, sardines, mackerel, also fish oil, krill oil and some algae supplements supply DHA. Without Omega-3, New CB1 Receptors are Made Imperfectly. See Also NUTRITION-HEMP SEED OIL, CBR-CB1 RECEPTORS)
OMEGA-6/ENDOCANNABINOID CONNECTION (Arachidonic acid, linoleic acid – Endocannabinoids are made from Omega-6, so you do need it, but it’s pro-inflammatory, so too much is not good for you. Modern diets can have up to 50 parts Omega 6 to 1 part Omega 3, when 3 to 4 parts Omega 6 to 1 part Omega 3 is optimal. Omega 6 is found corn, soy, safflower, grape seed, sunflower, and “mixed vegetable” oils.)
OMEGA-9
ORGANIC ACIDEMIAS (Group of Metabolic Disorders That Disrupt Normal Amino Acid Metabolism)
ORGAN TRANSPLANTS*+
OSTEOPOROSIS/BONES and CARTILAGE +
OVARIAN CYSTS +
OVERDOSES on CANNABINOIDS*+ (Natural Cannabinoid ‘Overdoses’ are NEVER Fatal. Overdoses on SYNTHETIC cannabinoids CAN be Fatal. See Also CANNABINOID HYPEREMESIS SYNDROME)
OVERDOSE PREVENTION-OPIATE/OPIOID
OVERVIEWS*+


OBESITY/ADIPOSE TISSUE
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice (full–2010) http://www.jneurosci.org/content/30/18/6273.long
Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full-2010) http://www.lipidworld.com/content/9/1/43
Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype (full–2010) http://ajpgi.physiology.org/content/299/1/G63.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c
Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution (full-2010) http://www.eje-online.org/content/163/3/407.full
The endocannabinoid system links gut microbiota to adipogenesis (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925525/
CD36 gene deletion decreases oleoylethanolamide levels in small intestine of freefeeding mice (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846762/?tool=pubmed
A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013130/?tool=pubmed
The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure (full-2010) http://onlinelibrary.wiley.com/doi/10.1038/oby.2008.509/full
Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868848/?tool=pubmed
The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food reinforced behavior (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522179/
Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912197/
A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055343/?tool=pubmed
Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes? (full–2010) http://www.jci.org/articles/view/44099? search[abstract_text]=&search[article_text]=cannabinoid&search[authors_text]=&search[fpage]=&search[t itle_text]=&search[volume]=
Modulation of Adipocyte Biology by Δ9-Tetrahydrocannabinol (full-2010) http://onlinelibrary.wiley.com/doi/10.1038/oby.2010.100/full
Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis (full-2010) http://www.nature.com/npp/journal/v35/n9/full/npp201058a.html
Perspectives of CB1 Antagonist in Treatment of Obesity: Experience of RIO-Asia (full–2010) http://www.hindawi.com/journals/jobes/2011/957268/
A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990160/
A one-year study to assess the safety and efficacy of the CB1R inverse agonist taranabant in overweight and obese patients with type 2 diabetes (full–2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1463-1326.2009.01188.x/full
A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: low-dose study (full–2010) http://www.nature.com/ijo/journal/v34/n5/full/ijo201021a.html
The endocannabinoid system modulates the valence of the emotion associated to food ingestion (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116974/ Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK path-ways (full–2010) http://diabetes.diabetesjournals.org/content/59/11/2826.full.pdf+html
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A randomised, double blind, placebo controlled, parallel group, pilot study of 1:1 and 20:1 ratio of formulated GW42003 : GW42004 plus GW42003 and GW42004 alone in the treatment of dyslipidaemia in subjects with Type 2 diabetes (research summary–2010) http://www.hra.nhs.uk/news/research-summaries/gwmd1092-gw42003gw42004-together-plus-alone-intype-ii-diabetes/#sthash.FT2P6YcB.dpuf
Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20936991
Analysis of gene expression pattern reveals potential targets of dietary oleoyl-ethanolamide in reducing body fat gain in C3H mice (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/19954948
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20851297
Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood (abst-2010) http://www.ncbi.nlm.nih.gov/pubmed/20013888
Cannabis Use and Obesity and Young Adults (abst-2010) http://informahealthcare.com/doi/abs/10.3109/00952990.2010.500438
Fructose affects enzymes involved in the synthesis and degradation of hypothalamic endocannabinoids (abst–2010) https://www.ncbi.nlm.nih.gov/pubmed/20085790 Nonalcoholic fatty liver disease: pathology and pathogenesis. (abst – 2010) https://www.ncbi.nlm.nih.gov/pubmed/20078219
Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function (full–2011) http://www.nutritionandmetabolism.com/content/8/1/93
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Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048484/?tool=pubmed
Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice (full–2011) http://www.nutritionandmetabolism.com/content/8/1/51
Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fat-fed mice (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111743/?tool=pubmed
The activity of the endocannabinoid metabolising enzyme fatty acid amide hydrolase in subcutaneous adipocytes correlates with BMI in metabolically healthy humans (full–2011) http://www.lipidworld.com/content/10/1/129
Effects of the cannabinoid-1 receptor antagonist rimonabant on psychiatric symptoms in overweight people with schizophrenia: a randomized, double-blind, pilot study (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717343/
Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084524/?tool=pubmed
The association of the rs1049353 polymorphism of the CNR1 gene with hypo-adiponectinemia (full–2011) http://www.rjme.ro/RJME/resources/files/520311791795.pdf
The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant’s antiobesity effects in mice (full–2011) http://onlinelibrary.wiley.com/doi/10.1038/oby.2011.250/full
Gadolinium-HU-308-incorporated micelles (full–2011) http://www.ncbi.nlm.nih.gov/books/NBK54067/pdf/CB2R-Gd-Micelles.pdf
Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise (full–2011) http://www.lipidworld.com/content/10/1/194
385 C/A polymorphism of the fatty acid amide hydrolase gene is associated with metabolic syndrome in the Chinese Han population (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258756/
Greasing the wheels of managing overweight and obesity with omega-3 fatty acids (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210336/
Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303536/
Association of genetic variation in cannabinoid mechanisms and gastric motor functions and satiation in overweight and obesity (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117918/
Obesity and Cannabis Use: Results From 2 Representative National Surveys (full–2011) http://aje.oxfordjournals.org/content/early/2011/08/24/aje.kwr200.full
Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038245/
The neutral cannabinoid CB₁ receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023913/
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Effects of Chronic Oral Rimonabant Administration on Energy Budgets of Diet-Induced Obese C57BL/6 Mice (full–2011) http://www.ncbi.nlm.nih.gov/pubmed/22173576
Expression of the cannabinoid system in muscle: effects of a high fat diet and CB1 receptor blockade (full–2011) http://www.biochemj.org/content/433/1/175
Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21326208
Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss (full–2011) http://www.nature.com/ijo/journal/v35/n11/full/ijo20118a.html
Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women? (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/20838400
Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women? (full–2011) http://www.nature.com/ijo/journal/v35/n3/full/ijo2010145a.html
Roles of G1359A polymorphism of the cannabinoid receptor gene (CNR1) on weight loss and adipocytokines after a hypocaloric diet (full–2011) http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112011000200012&lng=en&nrm=iso
Sweet taste and (AAT)12 repeat in the cannabinoid receptor gene in obese females (letter–2011) https://www.jstage.jst.go.jp/article/endocrj/58/4/58_K11E-093/_pdf
The role of central CB2 cannabinoid receptors on food intake in neonatal chicks (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21927979
Endocannabinoid signaling and energy metabolism: a target for dietary intervention (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21470818
Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors (abst-2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm
Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21336842
Screening of selected Asian spices for anti obesity-related bioactivities (abst–2011) http://www.sciencedirect.com/science/article/pii/S0308814610016870
To Be or Not To Be-Obese (full–2012) http://endo.endojournals.org/content/152/10/3592.long
The L-α-lysophosphatidylinositol/GPR55 system and its potential role in human obesity (full–2012) http://diabetes.diabetesjournals.org/content/61/2/281.long
Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function (full–2012) http://www.nutritionandmetabolism.com/content/pdf/1743-7075-8-93.pdf
Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism (full-2012) http://www.pnas.org/content/109/37/14966.long
Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity (full–2012) http://www.ncbi.nlm.nih.gov/pubmed/22829723?dopt=Abstract
Cannabinoid Receptor 1 (CNR1) 4895 C/T Genetic Polymorphism was Associated with Obesity in Japanese Men (full–2012) https://www.jstage.jst.go.jp/article/jat/19/8/19_12732/_pdf
Relationships between glucose, energy intake and dietary composition in obese adults with type 2 diabetes receiving the cannabinoid 1 (CB1) receptor antagonist, rimonabant (full–2012) http://www.nutritionj.com/content/11/1/50
Excess of the endocannabinoid anandamide during lactation induces overweight, fat accumulation and insulin resistance in adult mice (full–2012) http://www.dmsjournal.com/content/4/1/35
Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences (full–2012) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038609
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/
Over-Expression of Monoacylglycerol Lipase (MGL) in Small Intestine Alters Endocannabinoid Levels and Whole Body Energy Balance, Resulting in Obesity (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429419/
Type 2 Diabetes Associated Changes in the Plasma Non-Esterified Fatty Acids, Oxy-lipins and Endocannabinoids (full–2012) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0048852
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Endocannabinoids measurement in human saliva as potential biomarker of obesity (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409167/?tool=pubmed
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription (full-2012) http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02175.x/full
2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism (full – 2012) http://www.sciencedirect.com/science/article/pii/S1550413112000526
2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism (full–2012) http://ac.els-cdn.com/S1550413112000526/1-s2.0-S1550413112000526-main.pdf?_tid=186a88ec-7369-11e3-8095-00000aab0f02&acdnat=1388638277_735058a6f79f41a9199132aed604fdab
CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342253/
Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice (full–2012) http://press.endocrine.org/doi/full/10.1210/en.2012-1405
Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548985/
Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study (full–2012) http://press.endocrine.org/doi/full/10.1210/jc.2011-3018
Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE) (full–2012) http://fampra.oxfordjournals.org/content/29/5/521.full
Does rimonabant independently affect free fatty acid and glucose metabolism? (full–2012) http://www.ncbi.nlm.nih.gov/pubmed/22170727
Cannabinoid Type 1 Receptor Gene Polymorphism and Macronutrient Intake (full–2012) http://www.karger.com/Article/FullText/343563
The thrifty lipids: endocannabinoids and the neural control of energy conservation (full–2012) http://www.ncbi.nlm.nih.gov/pubmed/22622030
Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621143/
GPR119 as a fat sensor (full–2012) http://www.cell.com/trends/pharmacological-sciences/fulltext/S0165-6147%2812%2900054-5
Photoperiodic Changes in Endocannabinoid Levels and Energetic Responses to Altered Signalling at CB1 Receptors in Siberian Hamsters (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060156/
Neural Substrates Underlying Interactions between Appetite Stress and Reward (full–2012) https://www.karger.com/Article/FullText/338237 Gut microbiota and the development of obesity (full–2012) http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112012000500007&lng=en&nrm=iso&tlng=en
Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity (full–2012) http://www.nature.com/ijo/journal/v36/n6/full/ijo2011165a.html
The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/21981246
Cannabinoid signalling regulates inflammation and energy balance: The importance of the brain-gut axis (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22269477
Diet-dependent modulation of hippocampal expression of endocannabinoid signalingrelated proteins in cannabinoid antagonist-treated obese rats (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/23033907
Cannabis exposure associated with weight reduction and β-cell protection in an obese rat model (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22421529
Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-induced obese mice (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22473329
Overexpression of cannabinoid CB2 receptor in the brain induces hyperglycaemia and a lean phenotype in adult mice (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22487302
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Cannabinol and cannabidiol exert opposing effects on rat feeding patterns (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22543671
Stimulation of acumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22728691
Associations of variants of CNR1 with obesity and obesity-related traits in Chinese women (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22244745
The role of the endocannabinoid system in eating disorders: pharmacological implications (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22785439
The potential use of cannabidiol in the therapy of metabolic syndrome (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22430005
Role of G1359A polymorphism of the cannabinoid receptor gene on weight loss and adipocytokines levels after two different hypocaloric diets (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/21543209
The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22943701
Childhood Obesity and the Role of Dopamine D2 Receptor and Cannabinoid Receptor-1 Gene Polymorphisms (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/23057570
New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22674489
Fatty acid flux and oxidation are increased by rimonabant in obese women (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22445512
Dietary Linoleic Acid Elevates the Endocannabinoids 2-AG and Anandamide and Promotes Weight Gain in Mice Fed a Low Fat Diet (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889814/
The impact of marijuana use on glucose, insulin, and insulin resistance among US adults (full–2013) http://www.amjmed.com/article/S0002-9343%2813%2900200-3/fulltext
The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671751/
Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese zucker rats (full–2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063449
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men (full–2013) http://www.lipidworld.com/content/12/1/78
Alterations to Melanocortinergic, GABAergic and Cannabinoid Neurotransmission Associated with Olanzapine-Induced Weight Gain (full–2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033548
Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons (full–2013) http://www.pnas.org/content/110/24/E2229.full
Food for thought: hormonal, experiential, and neural influences on feeding and obesity (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818543/
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Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693401/
Orexin neurons use endocannabinoids to break obesity-induced inhibition (full–2013) http://www.pnas.org/content/110/24/9625.full
Effect of high fat-diet and obesity on gastrointestinal motility (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890396/
Insulin induces long-term depression of VTA dopamine neurons via endocannabinoids (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072656/
Cannabinoids, eating behaviour, and energy homeostasis (full–2013) http://onlinelibrary.wiley.com/doi/10.1002/dta.1594/full
Reduced Food Intake is the Major Contributor to the Protective Effect of Rimonabant on Islet in Established Obesity-Associated Type 2 Diabetes (full–2013) http://www.eymj.org/DOIx.php?id=10.3349/ymj.2013.54.5.1127
Developmental Role for Endocannabinoid Signaling in Regulating Glucose Metabolism and Growth (full–2013) http://diabetes.diabetesjournals.org/content/62/7/2359.full?sid=2f5bda2b-a9c7-432a-9588-80c99189164d
Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839776/
Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism (full-2013) http://tinyurl.com/zsrsh67
Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines (full–2013) http://eurheartj.oxfordjournals.org/content/34/27/2063.long
Fatty Acid Modulation of the Endocannabinoid System and the Effect on Food Intake and Metabolism (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677644/
Effect of Nelumbo nucifera Petal Extracts on Lipase, Adipogenesis, Adipolysis, and Central Receptors of Obesity (full–2013) http://www.hindawi.com/journals/ecam/2013/145925/
The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome (full–2013) http://www.cell.com/cell-reports/fulltext/S2211-1247%2813%2900507-X
A potential role for GPR55 in gastrointestinal functions (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660623/
Polymorphism rs3123554 in CNR2 reveals gender-specific effects on body weight and affects loss of body weight and cerebral insulin action (full–2013) http://onlinelibrary.wiley.com/doi/10.1002/oby.20573/full
Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827983/
High fat diet and body weight have different effects on cannabinoid CB1 receptor expression in rat nodose ganglia (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866822/
Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity (full–2013) http://www.placentajournal.org/article/S0143-4004%2813%2900692-9/fulltext
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies (full–2013) http://www.karger.com/Article/FullText/350094 Pathophysiology of Human Visceral Obesity: An Update (full–2013) http://physrev.physiology.org/content/93/1/359.long
A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2- arachidonoylglycerol with potential anti-obesity effects (full–2013) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687659/
Genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) and their influence on anthropometric parameters and metabolic parameters under a high monounsaturated vs. high polyunsaturated fat hypocaloric diets (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23337343
Cannabis and Δ(9)-tetrahydrocannabinol (THC) for weight loss? (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23410498
Endocannabinoids and obesity (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23374723
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Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21 (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23434135
Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23466458
The endocannabinoid system in obesity (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23596738
Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23620336
Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1α pathway (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23747418
Analysis of the “endocannabinoidome” in peripheral tissues of obese Zucker rats (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23830028
The Role of the Endocannabinoid System in Eating Disorders: Neurochemical and Behavioural Preclinical Evidence (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23829365
Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23932644
Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation,  insulin resistance, and adipose inflammation in high-fat fed mice (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23901038
Role of Genetic Variation in the Cannabinoid Receptor Gene (CNR1) (G1359A Poly-morphism) on Weight Loss and Cardiovascular Risk Factors After Liraglutide Treatment in Obese Patients With Diabetes Mellitus Type 2 (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24322329
Regulation of GPR55 in rat white adipose tissue and serum LPI by nutritional status, gestation, gender and pituitary factors (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24378736
The regulation of food intake by the gut-brain axis: implications for obesity (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/22710925
Concurrent pharmacological modification of cannabinoid-1 and glucagon-like peptide-1 receptor activity affects feeding behavior and body weight in rats fed a free-choice, highcarbohydrate diet (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24370558
Effects of C358A polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) on weight loss, adipocytokines levels, and insulin resistance after a high polyunsaturated fat diet in obese patients (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24445122
Marijuana and Body Weight (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204468/
Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882055/
Oleoylethanolamide: a novel potential pharmacological alternative to cannabinoid antagonists for the control of appetite (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996326/
Vascular targets for cannabinoids: animal and human studies (full–2014) http://onlinelibrary.wiley.com/doi/10.1111/bph.12560/full
Long-term changes in the ghrelin-CB1R axis associated with the maintenance of lower body weight after sleeve gastrectomy (full–2014) http://www.nature.com/nutd/journal/v4/n7/full/nutd201424a.html
A diet containing a nonfat dry milk matrix significantly alters systemic oxylipins and the endocannabinoid 2-arachidonoylglycerol (2-AG) in diet-induced obese mice (full–2014) http://www.nutritionandmetabolism.com/content/11/1/24
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Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895006/
The Endocannabinoid System – Back to the Scene of Cardiometabolic Risk Factors Control? (full–2014) https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1375653
The effects of obesity, diabetes and metabolic syndrome on the hydrolytic enzymes of the endocannabinoid system in animal and human adipocytes (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995979/
Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects (full–2014) http://onlinelibrary.wiley.com/doi/10.1002/oby.20728/full
Endocannabinoid Receptors Gene Expression in Morbidly Obese Women with Non-alcoholic Fatty Liver Disease (full–2014) http://www.hindawi.com/journals/bmri/2014/502542/
Dietary Non-Esterified Oleic Acid Decreases the Jejunal Levels of Anorectic NAcylethanolamines (full–2014) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100365
Effects of chaiyuwendan decoction on endocannabinoids levels in adipose tissue of rats with chronic stress-induced depression (full–2014) http://www.journaltcm.com/modules/Journal/contents/stories/141/16.pdf
Moderate-Vigorous Physical Activity across Body Mass Index in Females: Moderating Effect of Endocannabinoids and Temperament (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125187/
The effects of leptin in combination with a cannabinoid receptor 1 antagonist, AM 251, or cannabidiol on food intake and body weight in rats fed a high-fat or a free-choice high sugar diet (full–2014) http://www.jpp.krakow.pl/journal/archive/08_14/pdf/487_08_14_article.pdf
Molecular matchmaking between the popular weight-loss herb Hoodia gordonii and GPR119, a potential drug target for metabolic disorder (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210048/
Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing denovo synthesis of long-chain ceramides (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839256/
Behavioral effects of the cannabinoid CB1 receptor allosteric modulator ORG27569 in rats (full–2014) http://onlinelibrary.wiley.com/doi/10.1002/prp2.69/full
CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209357/
Neural Effects of Cannabinoid CB1 Neutral Antagonist Tetrahydrocannabivarin (THCv) on Food Reward and Aversion in Healthy Volunteers (full–2014) http://ijnp.oxfordjournals.org/content/18/6/pyu094.long
Genetic Sensitivity to the Bitter Taste of 6-n-Propylthiouracil (PROP) and Its Association with Physiological Mechanisms Controlling Body Mass Index (BMI) (full–2014) http://www.mdpi.com/2072-6643/6/9/3363/htm
Mitochondria: A Possible Nexus for the Regulation of Energy Homeostasis by the Endocannabinoid System? (full–2014) http://ajpendo.physiology.org/content/ajpendo/307/1/E1.full.pdf
Modulation of plasma N-acylethanolamine levels and physiological parameters by dietary fatty acid composition in humans (full–2014) http://www.jlr.org/content/55/12/2655.long
Oleoylethanolamide and Human Neural Responses to Food Stimuli in Obesity (full–2014) http://archpsyc.jamanetwork.com/article.aspx?articleid=1904805
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Baseline Anandamide Levels and Body Weight Impact the Weight Loss Effect of CB1 Receptor Antagonism in Male Rats (full–2014) http://press.endocrine.org/doi/10.1210/en.2014-1730#sthash.Fbslw7v2.dpuf
Cannabis use in relation to obesity and insulin resistance in the inuit population (full–2014) http://onlinelibrary.wiley.com/doi/10.1002/oby.20973/full
Endocannabinoid signaling and food addiction (full–2014) http://www.sciencedirect.com/science/article/pii/S0149763414002061
Haloperidol and rimonabant increase delay discounting in rats fed high-fat and standard chow diets (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25000488
Cannabinoid Type 1 (CB1) Receptors on Sim1-Expressing Neurons Regulate Energy Expenditure in Male Mice (abst–2014) http://press.endocrine.org/doi/10.1210/en.2014-1437#sthash.9q1rpqPq.dpuf
Cannabinoids, eating behaviour, and energy homeostasis (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24375977
CB1 blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/22828945
Glucose metabolism: Focus on gut microbiota, the endocannabinoid system and beyond (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24631413
Endocannabinoids and energy homeostasis: An update (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24752980
The endocannabinoid system and appetite: relevance for food reward (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24933167
GPR55: From orphan to metabolic regulator? (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24972076
Antipsychotic induced weight gain: genetics, epigenetics, and biomarkers reviewed (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25138234
Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25093427
Gut microbiota and obesity: Role in aetiology and potential therapeutic target (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25194177
Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25413674
The role of gut hormones in appetite regulation (review) (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25532952
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full–2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (DIO) via GIP secretion from enteroendocrine K-cells in response to fat ingestion (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25628425
Global deletion of monoacylglycerol lipase in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity (full–2015) http://www.jlr.org/content/early/2015/04/04/jlr.M058586.long
Leptin Levels Are Negatively Correlated with 2-Arachidonoylglycerol in the Cerebrospinal Fluid of Patients with Osteoarthritis (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383333/
Fat Diet-Induced Insulin Resistance Does Not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123558
Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons (full–2015)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423197/
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Dietary Triacylglycerols with Palmitic Acid in the sn-2 Position Modulate Levels of NAcylethanolamides in Rat Tissues (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361611/
A cannabinoid receptor agonist N-arachidonoyl dopamine inhibits adipocyte differentiation in human mesenchymal stem cells (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428713/
The endocannabinoid anandamide during lactation increases body fat content and CB1 receptor levels in mice adipose tissue (full–2015)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491858/
Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382707/
Tetrahydrocannabivarin (THCv) reduces Default Mode Network and increases Executive Control Network Resting State Functional Connectivity in Healthy Volunteers (full–2015) http://ijnp.oxfordjournals.org/content/early/2015/09/10/ijnp.pyv092.long
N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte (full–2015) http://www.sciencedirect.com/science/article/pii/S0006291X15305635
The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Child-hood Obesity and Age at Menarche (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140142
Anticipatory and consummatory effects of (hedonic) chocolate intake are associated with increased circulating levels of the orexigenic peptide ghrelin and endocannabinoids in obese adults (full–2015) http://www.foodandnutritionresearch.net/index.php/fnr/article/view/29678
Circulating Endocannabinoids and the Polymorphism 385C>A in Fatty Acid Amide Hydrolase (FAAH) Gene May Identify the Obesity Phenotype Related to Cardiometabolic Risk: A Study Conducted in a Brazilian Population of Complex Interethnic Admixture (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142728
Hypothalamic control of brown adipose tissue thermogenesis (full–2015) http://journal.frontiersin.org/article/10.3389/fnsys.2015.00150/full
Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with Δ9-Tetrahydrocannabinol (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144270
Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145244
METABOLIC EFFECTS OF MARIJUANA USE AMONG BLACKS (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523241/
Anti-Obesity Effect of the CB2 Receptor Agonist JWH-015 in Diet-Induced Obese Mice (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140592
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26219414
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression,
epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722239/
α/β Hydrolase Domain-Containing 6 (ABHD6) Degrades the Late Endosomal / Lysosomal Lipid Bis(monoacylglycero)phosphate (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705992/
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Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signalling Deficiency (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26081302
Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signalling Deficiency (full–2015) http://www.nature.com/npp/journal/v41/n2/full/npp2015173a.html
Role of the Endocannabinoid System in Diabetes and Diabetic Complications (full–2015) http://onlinelibrary.wiley.com/doi/10.1111/bph.13226/full
Cigarette smoking may modify the association between cannabis use and adiposity in males (full–2015) http://www.sciencedirect.com/science/article/pii/S0091305715001690
Association of G1359A polymorphism of the cannabinoid receptor gene (CNR1) with macronutrient intakes in obese females (full–2015) http://onlinelibrary.wiley.com/doi/10.1111/jhn.12298/full
Polymorphism G1359A of the cannabinoid receptor gene (CNR1): allelic frequencies and influence on cardiovascular risk factors in a multicentre study of Castilla-Leon (full–2015) http://onlinelibrary.wiley.com/doi/10.1111/jhn.12297/full
Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoylglycerol and arachidonoyl-ethanolamide, and their metabolites (full–2015) http://www.jleukbio.org/content/97/6/1049.long
Association between paracetamol use in infancy or childhood with body mass index (full–2015) http://onlinelibrary.wiley.com/doi/10.1002/oby.21045/full
Chronic administration with AM251 improves albuminuria and renal tubular structure in obese rats (full–2015) http://joe.endocrinology-journals.org/content/225/2/113.long
Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (DIO) via GIP secretion from enteroendocrine K-cells in response to fat ingestion (full–2015) http://ajpendo.physiology.org/content/308/7/E583.long Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461413/ The Cannabinoid Receptor-1 is an imaging biomarker of Brown Adipose Tissue (full–2015) http://jnm.snmjournals.org/content/56/12/1937.full.pdf+html
THE EFFECT OF MEDICAL MARIJUANA LAWS ON BODY WEIGHT (full–2015) The Effect of Medical Marijuana Laws on Body Weight Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice (full–2015) http://www.jnutbio.com/article/S0955-2863(15)00021-2/fulltext
Epigenetic and Proteomic Expression Changes Promoted by Eating Addictive-like Behavior (full–2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864655/
Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-arachidonoylglycerol (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26612385
Endocannabinoid system activation may be associated with insulin resistance in women with polycystic ovary syndrome (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25935491
Saliva of obese patients – is it different? (abst–2015) (click “ICI” for download–2015) http://www.ncbi.nlm.nih.gov/pubmed/26561845
The emerging role of the endocannabinoid system in the pathogenesis and treatment of kidney diseases (link to PDF–2015) http://www.degruyter.com/view/j/jbcpp.ahead-of-print/jbcpp-2015-0055/jbcpp-2015-0055.xml
Participation of the endocannabinoid system (ECS) in the weight-gain and sensitization to LPS exposure in a maternal obesity model (article–2015) http://www.placentajournal.org/article/S0143-4004%2815%2900526-3/fulltext
Two non-psychoactive cannabinoids reduce intra-cellular lipid levels and inhibit hepatosteatosis (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25595882
Effects of a High-Protein/Low-Carbohydrate versus a Standard Hypocaloric Diet on Weight and Cardiovascular Risk Factors during 9 Months: Role of a Genetic Variation in the Cannabinoid Receptor Gene (CNR1) (G1359A Polymorphism) (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25766592
Analysis of FABP4 expression pattern in rump fat deposition and metabolism of Altay sheep (abst–2015)  http://www.ncbi.nlm.nih.gov/pubmed/25665644
A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/26161824
Strain and sex differences in puberty onset and the effects of THC administration on weight gain and brain volumes (abst-2015) http://www.sciencedirect.com/science/article/pii/S0306452215006387
The endocannabinoid system role in the pathogenesis of obesity and depression (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26277182
Pro-inflammatory obesity in aged cannabinoid-2 receptor deficient mice (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26303348
New insights on the role of the endocannabinoid system in the regulation of energy balance (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26374449
Endocannabinoids and Metabolic Disorders (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26408168
The Endocannabinoid System: Pivotal Orchestrator of Obesity and Metabolic Disease (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26412154
The brain in bone and fuel metabolism (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26545334
Deletion of G-protein coupled receptor 55 promotes obesity by reducing physical activity (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26447738
Development and validation of an HPLC-MS method for the simultaneous quantification of key oxysterols, endocannabinoids, and ceramides: variations in metabolic syndrome (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26563111
Approaches for the development of drugs for treatment of obesity and metabolic syndrome (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26648466
Endocannabinoids – at the crossroads between the gut microbiota and host metabolism (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26678807
Cell type-specific modulation of lipid mediator’s formation in murine adipose tissue by omega-3 fatty acids (abst–2015) http://www.sciencedirect.com/science/article/pii/S0006291X15310603
Cannabis: a self-medication drug for weight management? The never ending story (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26456495
Lipid signaling in adipose tissue: Connecting inflammation & metabolism (abst–2015) http://www.sciencedirect.com/science/article/pii/S1388198114002091
Effects of dietary CLA on n-3 HUFA score and N-acylethanolamides biosynthesis in the liver of obese Zucker rats (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25912618 Intermittent access to liquid sucrose differentially modulates energy intake and related central pathways in control or high-fat fed mice (abst–2015) https://www.ncbi.nlm.nih.gov/pubmed/25484353
Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation (full–2016) http://www.jlr.org/content/early/2016/01/14/jlr.M065227.full.pdf+html?sid=da020ee7-4e2e-40b6-a400-27301739341e
Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine neuropathic pain model (full–2016) http://onlinelibrary.wiley.com/doi/10.1111/bph.13337/full
CB1 receptor blockade counters age-induced insulin resistance and metabolic dysfunction (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783351/
Exposure to a Highly Caloric Palatable Diet During Pregestational and Gestational Periods Affects Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Adiposity and Anxiety-Like Behaviors in Male Rat Offspring (full–2016) http://journal.frontiersin.org/article/10.3389/fnbeh.2015.00339/full
Vaccenic acid suppresses intestinal inflammation by increasing the endocannabinoid anandamide and non-cannabinoid signaling molecules in a rat model of the metabolic syndrome (full–2016) http://www.jlr.org/content/early/2016/02/17/jlr.M066308.long
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity (full–2016) http://www.mdpi.com/2072-6643/8/3/128/htm
New insights into the yin and yang of the endocannabinoid system in health and disease (full–2016) http://onlinelibrary.wiley.com/doi/10.1111/bph.13451/full
A Lower Olfactory Capacity Is Related to Higher Circulating Concentrations of Endocannabinoid 2-Arachidonoylglycerol and Higher Body Mass Index in Women (full–2016) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148734
Impaired Excitatory Neurotransmission in the Urinary Bladder from the Obese Zucker Rat: Role of Cannabinoid Receptors. (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902197/ Metabolic Syndrome Among Marijuana Users in the United States: An Analysis of National Health and Nutrition Examination Survey Data (full–2016) http://www.amjmed.com/article/S0002-9343(15)01024-4/fulltext
The potential relevance of the endocannabinoid, 2-arachidonoylglycerol, in diffuse large B-cell lymphoma (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751914/
Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679742/
Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction (full–2016) http://www.sciencedirect.com/science/article/pii/S2214647416300137
Endocannabinoids in Feeding Behavior and Energy Homeostasis (full–2016) http://themedicalbiochemistrypage.org/endocannabinoids.php
Association between cerebral cannabinoid 1 receptor availability and body mass index in patients with food intake disorders and healthy subjects: a [(18)F]MK-9470 PET study (full–2016) http://www.nature.com/tp/journal/v6/n7/full/tp2016118a.html
Mice Expressing a “Hyper-Sensitive” Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic (full–2016) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160462
Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism (full–2016) http://www.nature.com/articles/srep33302
Role of Gut Microbiota in the Aetiology of Obesity: Proposed Mechanisms and Review of the Literature (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040794/
Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring (full–2016) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165432
Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring (full–2016) http://journal.frontiersin.org/article/10.3389/fnbeh.2016.00208/full
Role of cannabinoid receptor 1 in human adipose tissue for lipolysis regulation and insulin resistance (full–2016) http://link.springer.com/article/10.1007%2Fs12020-016-1172-6
Cannabinoid 2 Receptor Agonist Improves Systemic Sensitivity to Insulin in High-Fat Diet/Streptozotocin-Induced Diabetic Mice (full–2016) https://www.karger.com/Article/FullText/453171
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity (full-2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808858/
Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855580/
Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123200/
α/β-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility (full–2016) http://www.cell.com/cell-reports/fulltext/S2211-1247(16)31373-0
Endocannabinoid regulation of β-cell functions: Implications for glycemic control and diabetes (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045244/
Early Low Fat Diet Enriched with Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High Fat Diet Challenge in Mice (full–2016) http://diabetes.diabetesjournals.org/content/65/7/1824.long
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166557/
Long-Term Effects of Prenatal Exposure to Undernutrition on Cannabinoid Receptor Related Behaviors: Sex and Tissue-Specific Alterations in the mRNA Expression of Cannabinoid Receptors and Lipid Metabolic Regulators (full–2016) http://journal.frontiersin.org/article/10.3389/fnbeh.2016.00241/full
Cannabinoid receptor 2 as anti-obesity target: inflammation, fat storage and browning modulation (link to PDF-2016) http://press.endocrine.org/doi/10.1210/jc.2015-4381?url_ver=Z39.88-2003&rfr_id=ori%3Arid %3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&
The CB1 neutral antagonist AM4113 retains the therapeutic efficacy of the inverse agonist rimonabant for nicotine dependence and weight loss, with better psychiatric tolerability (link to PDF–2016) http://ijnp.oxfordjournals.org/content/early/2016/08/03/ijnp.pyw068.long
The inhibitory effect of combination treatment with leptin and cannabinoid CB1 receptor agonist on food intake and body weight gain is mediated by serotonin 1B and 2C receptors (click Full Text Links for PDF–2016) http://www.ncbi.nlm.nih.gov/pubmed/27512006
Effects of activation of endocannabinoid system on myocardial metabolism (click “ICI” for download–2016) http://www.ncbi.nlm.nih.gov/pubmed/27333924
Responses of peripheral endocannabinoids and endocannabinoid-related compounds to hedonic eating in obesity (abst–2016) http://link.springer.com/article/10.1007/s00394-016-1153-9
Sex Differences in Cannabinoid-Regulated Biology: A Focus on Energy Homeostasis (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26800649
G protein-coupled receptor 18: A potential role for endocannabinoid signalling in metabolic dysfunction (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26337420
G protein-coupled receptor 18: A potential role for endocannabinoid signalling in metabolic dysfunction (full–2016) http://onlinelibrary.wiley.com/doi/10.1002/mnfr.201500449/full
Interactions between dietary oil treatments and genetic variants modulate fatty acid ethanolamides in plasma and body weight composition (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26806592
Cannabinoid receptor type 1 mediates high-fat diet-induced insulin resistance by increasing forkhead box O1 activity in a mouse model of obesity (abst–2016) http://www.spandidos-publications.com/10.3892/ijmm.2016.2475
Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26880264
Regulation of Growth Hormone by the Splanchnic Area (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26940386
Role of cannabinoid receptors in renal diseases (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26968477
SGIP1 Alters Internalization and Modulates Signaling of Activated Cannabinoid Receptor 1 in Biased Manner (abst–2016) http://www.sciencedirect.com/science/article/pii/S0028390816300806
Cannabidiol promotes browning in 3T3-L1 adipocytes (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27067870
Fatty Acid Binding Protein-1 (FABP1) and the Human FABP1 T94A Variant: Roles in the Endocannabinoid System and Dyslipidemias (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27117865
Driving the need to feed: Insight into the collaborative interaction between ghrelin and endocannabinoid systems in modulating brain reward systems (abst–2016) http://www.sciencedirect.com/science/article/pii/S0149763415301494
Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27155918
Decision-Making Does not Moderate the Association between Cannabis Use and Body Mass Index among Adolescent Cannabis Users (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27079834
Genetic polymorphisms in genes related to risk-taking behaviours predicting body mass index trajectory among Mexican American adolescents (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27228958
Simultaneous HPLC-APCI-MS/MS quantification of endogenous cannabinoids and glucocorticoids in hair (abst–2016) http://www.sciencedirect.com/science/article/pii/S1570023216303786
LINOLEIC ACID AND THE PATHOGENESIS OF OBESITY (abst–2016) http://www.sciencedirect.com/science/article/pii/S1098882316300363
Endocannabionoid System in Neurological Disorders (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27364363
Formation of OX-1R/CB1R heteromeric complexes in embryonic mouse hypothalamic cells: Effect on intracellular calcium, 2-arachidonoyl-glycerol biosynthesis and ERK phosphorylation (abst–2016) http://www.sciencedirect.com/science/article/pii/S1043661816306612
Cannabis and a lower BMI in psychosis: What is the role of AKT1? (abst–2016) http://www.schres-journal.com/article/S0920-9964(16)30364-4/abstract
Disturbances of sleep and circadian rhythms: novel risk factors for obesity (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27584008
Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome (abst-2016) http://www.ncbi.nlm.nih.gov/pubmed/27651218
Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation (abst–2016) http://www.sciencedirect.com/science/article/pii/S0378427416331472
Marijuana Use and Type 2 Diabetes Mellitus: a Review (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27747490
The role of perivascular adipose tissue in obesity-induced vascular dysfunction (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27761903
Fabp1 gene ablation inhibits high fat diet-induced increase in brain endocannabinoids (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27861894
Cannabimimetic phytochemicals in the diet – an evolutionary link to food selection and metabolic stress adaptation? (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27891602
Got Munchies? Estimating the Relationship between Marijuana Use and Body Mass Index (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27572145
Using proteomics to discover novel biomarkers for fatty liver development and response to CB1R antagonist treatment in an obese mouse model (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27928909
Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27959272
Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27989579
Association Between Use of Cannabis in Adolescence and Weight Change into Midlife (link to download–2017) http://journals.plos.org/plosone/article? id=10.1371/journal.pone.0168897
Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity (abst–2017) https://www.ncbi.nlm.nih.gov/pubmed/28065722
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OBSESSIVE COMPULSIVE DISORDER/OCD
Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20695034
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay  (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034086/pdf/nihms262924.pdf
Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370
Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug (full-2012) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462012000500008&lng=en&nrm=iso&tlng=en
Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481531/
Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22248639
Cannabidiol reverses the mCPP-induced increase in marble-burying behavior (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24118015
β-Caryophyllene, a CB2 Receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24930711
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Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25340977
Cannabidiol as a Potential Treatment for Anxiety Disorders (abst–2015) http://link.springer.com/article/10.1007/s13311-015-0387-1
Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation (full–2016) http://www.cell.com/neuron/fulltext/S0896-6273%2816%2930157-X


OLDER ADULTS
The use of Cannnabidiol (CBD) to Reduce Insomnia and the Urge To Use Alcohol in a Geriatric person in on going Behavior Therapy (case report–undated) http://cannabisclinicians.org/view-all-case-reports/entry/420/?pagenum=2 Illicit and Nonmedical Drug Use Among Older Adults: A Review (link to PDF–2010) http://journals.sagepub.com/doi/abs/10.1177/0898264310386224
Marijuana use among older adults in the U.S.A.: user characteristics, patterns of use, and implications for intervention (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21108863
Prevalences of illicit drug use in people aged 50 years and over from two surveys (full–2012) http://ageing.oxfordjournals.org/content/41/4/553.long
Statistics on cannabis users skew perceptions of cannabis use (full–2013) http://journal.frontiersin.org/article/10.3389/fpsyt.2013.00138/full
Still Dazed and Confused: Midlife Marijuana Use by the Baby Boom Generation (abst–2013) http://www.tandfonline.com/doi/abs/10.1080/01639625.2014.889994
New insights into the physiology of bone regulation: the role of neuro-hormones (full–2014) http://www.biomed.cas.cz/physiolres/pdf/prepress/932668.pdf
Therapeutic benefits of cannabis: a patient survey (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998228/
The endocannabinoid system and appetite: relevance for food reward (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24933167
Safety and pharmacokinetics of oral delta-9-tetrahydrocannabinol in healthy older subjects: A randomized controlled trial (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25035121
The successful use of dronabinol for failure to thrive secondary to intestinal dysmotility (full–2015) http://www.casereports.com/article/S2210-2612%2815%2900219-9/pdf
Use of Prescription Pain Medications Among Medical Cannabis Patients: Comparisons of Pain Levels, Functioning, and Patterns of Alcohol and Other Drug Use (full–2015) http://ssw.umich.edu/sites/default/files/documents/news/use-of-prescription-pain-medications-amongmedical-cannabis-patients.pdf
PROGRESS REPORT Compassionate Use of Medical Cannabis Pilot Program Act July 1, 2014 through June 30, 2015 (full–2015)
http://dph.illinois.gov/sites/default/files/publications/publicationohpmmedical-cannabis-annual-report-2015.pdf
Responsible and controlled use: Older cannabis users and harm reduction (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25911027
Safety, pharmacodynamics, and pharmacokinetics of multiple oral doses of delta-9-tetrahydrocannabinol in older persons with dementia (abst-2015)
http://link.springer.com/article/10.1007/s00213-015-3889-y/fulltext.html
The Effect of Medical Marijuana Laws on Body Weight (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26602324
THE EFFECT OF MEDICAL MARIJUANA LAWS ON BODY WEIGHT (full–2015) http://www.os-extra.cannabisclinicians.org/wp-content/uploads/2016/03/MMJ_laws_Body-weight.pdf
Cannabinoids in late-onset Alzheimer’s disease (full–2015) http://onlinelibrary.wiley.com/doi/10.1002/cpt.117/full
A safer alternative: Cannabis substitution as harm reduction (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25919477
Substituting cannabis for prescription drugs, alcohol and other substances among medical cannabis patients: The impact of contextual factors (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26364922
With education, nurses can help to bridge the marijuana gap (article–2015) http://cannabistoday.bangordailynews.com/2015/07/09/home/with-education-nurses-can-help-to-bridgethe-marijuana-gap/
Patterns of cannabis use in patients with Inflammatory Bowel Disease: A population based analysis (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26422462
National Estimates of Marijuana Use and Related Indicators — National Survey on Drug Use and Health, United States, 2002–2014 (full–2016) http://www.cdc.gov/mmwr/volumes/65/ss/ss6511a1.htm?s_cid=ss6511a1_e
Medical Marijuana Laws Reduce Prescription Medication Use In Medicare Part D (full–2016) http://content.healthaffairs.org/content/35/7/1230.long
Older-adult marijuana users and ex-users: Comparisons of sociodemographic characteristics and mental and substance use disorders (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27282425
Agitation in Alzheimer Disease as a Qualifying Condition for Medical Marijuana in the United States (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27389672
Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets (abst–2016) http://www.sciencedirect.com/science/article/pii/S1388198116302013
Bongs and baby boomers: Trends in cannabis use among older Australians (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27730759
Older marijuana users: Life stressors and perceived social support (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27776245
Pros and cons of medical cannabis use by people with chronic brain disorders (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27804883
The Impact of Medical Marijuana Laws on the Labor Supply and Health of Older Adults: Evidence from the Health and Retirement Study (abst–2016) http://www.nber.org/papers/w22688
Accidental cannabis poisoning in the elderly (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27900531
Demographic trends among older cannabis users in the United States, 2006–13 (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27767235
From adolescent to elder rats: Motivation for palatable food and cannabinoids receptors (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27935269
Protective effects of trans-caryophyllene on maintaining osteoblast function (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/28026135
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OMEGA-3/CB1 CONNECTION
Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed
Maternal Dietary Fat Determines Metabolic Profile and the Magnitude of Endo-cannabinoid Inhibition of the Stress Response in Neonatal Rat Offspring (full–2010) http://endo.endojournals.org/content/151/4/1685.full?sid=f9729cff-d221-42d4-81d8-8545db5df878
Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma (full–2010)
http://www.jlr.org/content/51/6/1416.full.pdf+html
Pitfalls in the sample preparation and analysis of N-acylethanolamines (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936757/
Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20013888
Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice (full–2011) http://www.nutritionandmetabolism.com/content/8/1/51
Fish oil promotes survival and protects against cognitive decline in severely under-nourished mice by normalizing satiety signals (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117120/
A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215906/
Greasing the wheels of managing overweight and obesity with omega-3 fatty acids (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210336/
Hepatic n-3 Polyunsaturated Fatty Acid Depletion Promotes Steatosis and Insulin
Resistance in Mice: Genomic Analysis of Cellular Targets (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154437/
N-Docosahhexanoyllethanolamide promotes development of hippocampal neurons (full–2011) http://www.biochemj.org/content/435/2/327
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21278728
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions Figure 1: n-3/n-6 PUFA dietary imbalance alters PUFAs level in mouse brain (charts–2011) http://www.nature.com/neuro/journal/v14/n3/fig_tab/nn.2736_F1.html
Endocannabinoid signaling and energy metabolism: a target for dietary intervention (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21470818
Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines (abst-2011) http://www.ncbi.nlm.nih.gov/pubmed/21995886
Functional Metabolomics Reveals Novel Active Products in the DHA Metabolome (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342038/?tool=pubmed
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/
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Type 2 Diabetes Associated Changes in the Plasma Non-Esterified Fatty Acids, Oxylipins and Endocannabinoids (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493609/
Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483099/
N-acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids – From fishy endocannabinoids to potential leads (full–2012) http://onlinelibrary.wiley.com/doi/10.1111/bph.12030/full
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
Searching for health beneficial n-3 and n-6 fatty acids in plant seeds (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380567/
Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548985/
The biochemical complexity of the endocannabinoid system with some remarks on stress and related disorders: a minireview (link to PDF-2012) http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=2854&category_id=93&keyword=cannabinoid&option=com_virtuemart&Itemid=1
Nutritional n-3 polyunsaturated fatty acids deficiency alters cannabinoid receptor signaling pathway in the brain and associated anxiety-like behavior in mice (abst–2012) http://www.springerlink.com/content/ur5784gm34782505/
Essential fatty acids and lipid mediators. Endocannabinoids (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22730630
Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/23103355
Effect of omega-3 polyunsaturated fatty acids on the endocannabinoid system in osteoblast-like cells and muscle (abst–2012) http://docs.lib.purdue.edu/dissertations/AAI3444794/
Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22805989
Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22051448
Nutritional suitability of linseed and oil hemp from fatty acids profile perspective (abst-2012) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1320816
Effect of dietary fat type on anxiety-like and depression-like behavior in mice (full–2013) http://www.springerplus.com/content/2/1/165
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men (full–2013) http://www.lipidworld.com/content/12/1/78
Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex (full–2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0081459
Nutritional suitability of linseed and oil hemp from fatty acids profile perspective (abst–2012) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1320816
Effect of dietary fat type on anxiety-like and depression-like behavior in mice (full–2013) http://www.springerplus.com/content/2/1/165
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men (full–2013) http://www.lipidworld.com/content/12/1/78
Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex (full–2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0081459
Nutritional properties of dietary omega-3-enriched phospholipids (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747496/
Association of Expanded Disability Status Scale and Cytokines after Intervention with Co-supplemented Hemp Seed, Evening Primrose Oils and Hot-natured Diet in Multiple Sclerosis Patients (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648912/
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Synaptamide, endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541447/
Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism (full-2013) http://journals.cambridge.org/action/displayFulltext?type=6&fid=8904779&jid=BJN&volumeId=109&issueId=09&aid=8904778&bodyId=&membershipNumber=&societyETOCSession=&fulltextType=RV&fileId=S000711451200579X
Endocannabinoid system as a potential mechanism for n-3 long-chain polyunsaturated fatty acid mediated cardiovascular protection (full–2013) http://tinyurl.com/z4dhzm7
PUFA-derived endocannabinoids: an overview (full–2013) http://tinyurl.com/h83m7nj
Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury (full–2013) http://www.sciencedirect.com/science/article/pii/S0306452213007835
Chemical Composition and Characterization of Hemp (Cannabis sativa) Seed oil and essential fatty acids by HPLC Method (full–2013) http://scholarsresearchlibrary.com/aasr-vol5-iss1/AASR-2013-5-1-5-8.pdf
Acyl migration evaluation in monoacylglycerols from Echium plantagineum seed oil and Marinol (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23287502
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies (full–2013) http://www.karger.com/Article/FullText/350094
DHA prevents altered 5-HT1(A), 5-HT2(A), CB1 and GABA(A) receptor binding densities in the brain of male rats fed a high-saturated-fat diet (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23337348
Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids and obesity (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23466458
Polyunsaturated Fatty Acid-Derived Lipid Mediators and T Cell Function (full–2014) http://www.ncbi.nlm.nih.gov/pubmed/24611066
Docosahexaenoyl ethanolamide improves glucose uptake and alters endocannabinoid system gene expression in proliferating and differentiating C2C12 myoblasts (full–2014) http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00100/full
Endogenous Signaling by Omega-3 Docosahexaenoic Acid-derived MediatorsSustains Homeostatic Synaptic and Circuitry Integrity (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180614/
Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target? (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057893/
Modulation of plasma N-acylethanolamine levels and physiological parameters by dietary fatty acid composition in humans (full–2014) http://www.jlr.org/content/55/12/2655.long
Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors (full–2014) http://www.nature.com/npp/journal/v39/n8/pdf/npp201432a.pdf
Nutritional omega-3 modulates neuronal morphology in the prefrontal cortex along with depression-related behaviour through corticosterone secretion (full–2014) http://www.nature.com/tp/journal/v4/n9/full/tp201477a.html
Potential Oil Yield, Fatty Acid Composition, and Oxidation Stability of the Hempseed Oil from Four Cannabis sativa L. Cultivars (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24552275
Endocannabinoid signaling and its regulation by nutrients (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24753395
Hempseed oil induces reactive oxygen species- and C/EBP homologous protein-mediated apoptosis in MH7A human rheumatoid arthritis fibroblast-like synovial cells (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24814038
Cannabinoid receptor antagonists and fatty acids alter endocannabinoid system gene expression and COX activity (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24854955
Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24934168
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Cannabinoid receptor antagonists and fatty acids alter endocannabinoid system gene expression and COX activity (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24854955
Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24934168
Cannabinoid receptor expression in femora and tibiae of C57/blk6 mice fed DHA and relationship to bone ash and BMC (bone mineral content) (abst–2014) http://www.fasebj.org/content/28/1_Supplement/1032.2.abstract?sid=467bb529-0ecc-4ddc-af27-3f56f520a102
Relationship between cannabinoids content and composition of fatty acids in hempseed oils (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/25306338
Omega-3 fatty acid production from enzyme saccharified hemp hydrolysate using a novel marine thraustochytrid strain (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25497057
Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti-inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages (full–2015) http://onlinelibrary.wiley.com/doi/10.1111/bph.12747/full
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full–2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26219414
Nitric oxide secretion in human conjunctival fibroblasts is inhibited by alpha linolenic acid (full–2015) http://www.ncbi.nlm.nih.gov/pubmed/26500455
Fetal endocannabinoids orchestrate the organization of pancreatic islet micro-architecture (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26494286
Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653226/
Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice (full–2015) http://www.jnutbio.com/article/S0955-2863(15)00021-2/fulltext
Polyunsaturated fatty acids and inflammation (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26397837
Polyunsaturated fatty acids and inflammation (full–2015) http://onlinelibrary.wiley.com/doi/10.1002/iub.1428/full
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25958314
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress (full–2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522350/
Distribution of Bioactive Lipid Mediators in Human Skin (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25668241
Fatty acids, endocannabinoids and inflammation (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26325095
Biosynthesis and Fate of Endocannabinoids (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26408157
Cell type-specific modulation of lipid mediator’s formation in murine adipose tissue by omega-3 fatty acids (abst–2015) http://www.sciencedirect.com/science/article/pii/S0006291X15310603
Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells (full–2016) http://www.sciencedirect.com/science/article/pii/S2213231716301252
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity (full-2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808858/
Modulation of Long-Term Potentiation of Cortico-Amygdala Synaptic Responses and Auditory Fear Memory by Dietary Polyunsaturated Fatty Acid (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993868/
Early Low Fat Diet Enriched with Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High Fat Diet Challenge in Mice (full–2016) http://diabetes.diabetesjournals.org/content/65/7/1824.long
Effects of Different Levels of Hemp Seed (Cannabis Sativa L.) and Dextran Oligosaccharide on Growth Performance and Antibody Titer Response of Broiler Chickens (full–2016) http://www.tandfonline.com/doi/full/10.4081/ijas.2015.3473
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166557/
Lifelong imbalanced linoleic/alpha-linolenic acid intake impairs emotional and cognitive behavior in adult rats via changes in brain endocannabinoid system. (click “Full Text Links” to download–2016) https://www.ncbi.nlm.nih.gov/pubmed/27903595
Interactions between dietary oil treatments and genetic variants modulate fatty acid ethanolamides in plasma and body weight composition (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26806592
Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26946127
Distinctive effects of eicosapentaenoic and docosahexaenoic acids in regulating neural stem cell fate are mediated via endocannabinoid signalling pathways (abst–2016) http://www.sciencedirect.com/science/article/pii/S0028390816301277
Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27155918
Analysis of Omega-3 Fatty Acid Derived N-Acylethanolamines in Biological Matrices (abst–2016) http://link.springer.com/protocol/10.1007%2F978-1-4939-3539-0_4
Docosahexaenoic acid attenuates in endocannabinoid synthesis in RAW 264.7 macrophages activated with benzo(a)pyrene and lipopolysaccharide (abst–2016) http://www.sciencedirect.com/science/article/pii/S0378427416301667
Association between plasma endocannabinoids and appetite in hemodialysis patients: A pilot study (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27333956
Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets (abst–2016) http://www.sciencedirect.com/science/article/pii/S1388198116302013
Docosahexaenoyl Serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23–IL-17 signalling in macrophages (abst–2016) http://www.sciencedirect.com/science/article/pii/S1388198116302499
Dietary Supplement Therapies for Inflammatory Bowel Disease: Crohn’s Disease and Ulcerative Colitis (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/26561079


OMEGA-6/ENDOCANNABINOID CONNECTION
Exposure to a high-fat diet decreases sensitivity to Δ9-tetrahydrocannabinol-induced motor effects in female rats (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014410/
Pitfalls in the sample preparation and analysis of N-acylethanolamines (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936757/
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Hepatic n-3 Polyunsaturated Fatty Acid Depletion Promotes Steatosis and Insulin Resistance in Mice: Genomic Analysis of Cellular Targets (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154437/
Endocannabinoid signaling and energy metabolism: a target for dietary intervention (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21470818
Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548985/
N-acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids – From fishy endocannabinoids to potential leads (full–2012) http://onlinelibrary.wiley.com/doi/10.1111/bph.12030/full
Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/
Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483099/
Searching for health beneficial n-3 and n-6 fatty acids in plant seeds (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380567/
Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/23103355
Nutritional suitability of linseed and oil hemp from fatty acids profile perspective (abst–2012) https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1320816
Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex (full–2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0081459
Association of Expanded Disability Status Scale and Cytokines after Intervention with Co-supplemented Hemp Seed, Evening Primrose Oils and Hot-natured Diet in Multiple Sclerosis Patients (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648912/
PUFA-derived endocannabinoids: an overview (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24020830
Chemical Composition and Characterization of Hemp (Cannabis sativa) Seed oil and essential fatty acids by HPLC Method (full–2013) http://scholarsresearchlibrary.com/aasr-vol5-iss1/AASR-2013-5-1-5-8.pdf
Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system (abst–2013) http://onlinelibrary.wiley.com/doi/10.1002/jnr.23231/abstract
Polyunsaturated Fatty Acid-Derived Lipid Mediators and T Cell Function (full–2014) http://www.ncbi.nlm.nih.gov/pubmed/24611066
Docosahexaenoyl ethanolamide improves glucose uptake and alters endocannabinoid system gene expression in proliferating and differentiating C2C12 myoblasts (full–2014) http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00100/full
Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target? (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24576779
Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24518289
Potential Oil Yield, Fatty Acid Composition, and Oxidation Stability of the Hempseed Oil from Four Cannabis sativa L. Cultivars (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24552275
Endocannabinoid signaling and its regulation by nutrients (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24753395
Gamma-linolenic acid egg production enriched with hemp seed oil and evening primrose oil in diet of laying hens (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25004746
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Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24934168
Relationship between cannabinoids content and composition of fatty acids in hemp seed oils (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25306338
The endocannabinoid system: directing eating behavior and macronutrient metabolism (full–2015) http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01506/full
Lipid mediator profile in vernix caseosa reflects skin barrier development (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629127/
Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26219414
Polyunsaturated fatty acids and inflammation (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26397837
Diet-induced changes in n-3 and n-6 derived endocannabinoids and reductions in headache pain and psychological distress (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25958314
Fatty acids, endocannabinoids and inflammation (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26325095
Biosynthesis and Fate of Endocannabinoids (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26408157
Lipid signaling in adipose tissue: Connecting inflammation & metabolism (abst–2015) http://www.sciencedirect.com/science/article/pii/S1388198114002091
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity (full–2016) http://www.mdpi.com/2072-6643/8/3/128/htm
Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells (full–2016) http://www.sciencedirect.com/science/article/pii/S2213231716301252
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity (full-2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808858/
Modulation of Long-Term Potentiation of Cortico-Amygdala Synaptic Responses and Auditory Fear Memory by Dietary Polyunsaturated Fatty Acid (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993868/
Early Low Fat Diet Enriched with Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High Fat Diet Challenge in Mice (full–2016) http://diabetes.diabetesjournals.org/content/65/7/1824.long
Effects of Different Levels of Hemp Seed (Cannabis Sativa L.) and Dextran Oligosaccharide on Growth Performance and Antibody Titer Response of Broiler Chickens (full–2016) http://www.tandfonline.com/doi/full/10.4081/ijas.2015.3473
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin /+ transgenic mice (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166557/
Lifelong imbalanced linoleic/alpha-linolenic acid intake impairs emotional and cognitive behavior in adult rats via changes in brain endocannabinoid system. (click “Full Text Links” to download–2016) https://www.ncbi.nlm.nih.gov/pubmed/27903595
Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27155918
Dietary conjugated linoleic acid supplementation alters the expression of genes involved in the endocannabinoid system in the bovine endometrium and increases plasma progesterone concentrations (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27262886
Association between plasma endocannabinoids and appetite in hemodialysis patients: A pilot study (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27333956
LINOLEIC ACID AND THE PATHOGENESIS OF OBESITY (abst–2016) http://www.sciencedirect.com/science/article/pii/S1098882316300363
Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets (abst–2016) http://www.sciencedirect.com/science/article/pii/S1388198116302013


OMEGA-9
Pitfalls in the sample preparation and analysis of N-acylethanolamines (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936757/
Multiple Changes in Peptide and Lipid Expression Associated with Regeneration in the Nervous System of the Medicinal Leech (link to PDF–2011) http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.713.3790&rank=102
Targeted mutation of Δ12 and Δ15 desaturase genes in hemp produce major alterations in seed fatty acid composition including a high oleic hemp oil (full–2014) http://onlinelibrary.wiley.com/doi/10.1111/pbi.12167/epdf
Your Next Cooking Oil Could Come From Hemp (news–2014) http://www.popsci.com/article/science/your-next-cooking-oil-could-come-hemp
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166557/


ORGANIC ACIDEMIAS
The effect of WIN 55,212-2 suggests a cannabinoid-sensitive component in the early toxicity induced by organic acids accumulating in glutaric acidemia type I and in related disorders of propionate metabolism in rat brain synaptosomes (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26431622
Experimental Evidence that 3-Methylglutaric Acid Disturbs Mitochondrial Function and Induced Oxidative Stress in Rat Brain Synaptosomes: New Converging Mechanisms (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27278758


ORGAN TRANSPLANTS
Do cannabinoids have a therapeutic role in transplantation? (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923447/?toolubmed
Denial of hepatic transplantation on the basis of smoking: is it ethical? (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20154621
Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model (full–2011) http://jpet.aspetjournals.org/content/early/2011/06/14/jpet.111.182717.long
Prolonged excretion half-life of 11-nor-9-carboxy-Δ⁹-THC following cessation in a chronic, heavy marijuana user: implications for liver transplant assessment (1st page–2011) http://www.psychosomaticsjournal.com/article/S0033-3182%2810%2900028-9/abstract
Cannabinoids Inhibit T-cells via Cannabinoid Receptor 2 in an In Vitro Assay for Graft Rejection, the Mixed Lymphocyte Reaction (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23824763
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Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury (full–2015) http://www.karger.com/Article/Pdf/430165
Circulating endocannabinoids during hematopoietic stem cell transplantation: A pilot study (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26114153
Circulating endocannabinoids during hematopoietic stem cell transplantation: A pilot study (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476410/
Effects of Cannabinoids on T-cell Function and Resistance to Infection (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25876735
A CB2-Selective Cannabinoid Suppresses T-Cell Activities and Increases Tregs and IL-10 (abst–2015) http://link.springer.com/article/10.1007/s11481-015-9611-3
Δ9-Tetrahydrocannabinol attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26034207
Cannabidiol for the Prevention of Graft-Versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26033282
The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation : a case report (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26507533
N-acyl dopamine derivates as lead compound for implementation in transplantation medicine (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25576467
Effects of Cannabinoids on T-cell Function and Resistance to Infection (full–2015) http://tinyurl.com/o3jbfsd
N-acyl dopamine derivates as lead compound for implementation in transplantation medicine (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25576467
The cannabinoid receptor 2 is involved in acute rejection of cardiac allografts (abst–2015) http://www.sciencedirect.com/science/article/pii/S0024320515001290
The cannabinoid receptor 2 is involved in acute rejection of cardiac allografts (abst–2015) http://www.sciencedirect.com/science/article/pii/S0024320515001290
High on Cannabis and Calcineurin Inhibitors: A Word of Warning in an Era of Legalized Marijuana (full–2016) https://www.hindawi.com/journals/crit/2016/4028492/
Cannabidiol limits Tcell-mediated chronic autoimmune myocarditis: implications to autoimmune disorders and organ transplantation (abst–2016)
http://www.ncbi.nlm.nih.gov/pubmed/26772776
Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type-2 Diabetes (abst–2017) http://diabetes.diabetesjournals.org/content/early/2017/01/11/db16-1199.long
Influence of history of cannabis smoking in selected donors on the outcomes of lung transplantation (abst–2017) https://www.ncbi.nlm.nih.gov/pubmed/28077504


OSTEOPOROSIS/BONES and CARTILAGE
Hypothalamic regulation of bone (full–2010) http://jme.endocrinology-journals.org/cgi/content/full/45/4/175
Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001217/?tool=pubmed
Tissue Engineering of Cartilage; Can Cannabinoids Help? (full–2010) http://www.tara.tcd.ie/bitstream/2262/40674/1/Tissue%20Engineering%20of%20Cartilage%20-%20Can%20Cannabinoids%20Help.pdf
Endocannabinoids Are Expressed in Bone Marrow Stromal Niches and Play a Role in Interactions of Hematopoietic Stem and Progenitor Cells with the Bone Marrow Micro-environment (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975171/?tool=pubmed
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss (full-2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871326/
CB2 Cannabinoid Receptor Targets Mitogenic Gi Protein–Cyclin D1 Axis in Osteoblasts (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179350/
Cannabinoids and Bone: Friend or Foe? (abst-2010) http://www.ncbi.nlm.nih.gov/pubmed/20532878
Activation of cannabinoid receptor CB2 regulates osteogenic and osteoclastogenic gene expression in human periodontal ligament cells (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20412420
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The endocannabinoid signaling system: a marriage of PUFA and musculoskeletal health (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20934863
Control of bone remodeling by nervous system. Nervous system and bone (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/21123931
Peripheral cannabinoid type 2 receptor regulates osteoclast formation, MDA-MB-231 breast cancer cell migration and bone marrow/tumour cell interaction via PI3 kinase/AKT and P38 pathways (abst–2010) http://www.thebonejournal.com/article/S8756-3282%2810%2901828-4/abstract
Loss of the cannabinoid receptor CB2 alters the mechanical but not the material properties of bone (abst–2010) http://www.thebonejournal.com/article/S8756-3282%2810%2900716-7/abstract
The type 2 cannabinoid receptor protects against age-related bone loss and ovariectomy induced bone loss by stimulating bone formation (abst–2010) http://www.thebonejournal.com/article/S8756-3282%2810%2900619-8/abstract
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro (full–2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01519.x/full
The Type 2 Cannabinoid Receptor Regulates Bone Mass and Ovariectomy-Induced Bone Loss by Affecting Osteoblast Differentiation and Bone Formation (full–2011) http://press.endocrine.org/doi/full/10.1210/en.2010-0930
Skeletal lipidomics: regulation of bone metabolism by fatty acid amide family (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165954/
Honokiol isolated from Magnolia officinalis stimulates osteoblast function and inhibits the release of bone-resorbing mediators (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21621646
The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21237298
The role of cannabinoid receptors in bone remodeling in a CB1/2 double knockout mouse (abst–2011) http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/492.5?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcetype=HWCIT
Paracetamol (acetaminophen) use, fracture and bone mineral density (abst–2011) http://www.thebonejournal.com/article/S8756-3282%2811%2900528-X/abstract
Expression of cannabinoid receptors by human articular chondrocytes (abst–2011) http://www.thebonejournal.com/article/S8756-3282%2811%2900386-3/abstract
The CB2 receptor regulates osteoclast formation, breast cancer cell migration and osteoclast/tumour cell interaction via the PI3 Kinase/AKT pathway (abst–2011) http://www.thebonejournal.com/article/S8756-3282%2811%2900177-3/abstract
Role of cannabinoids in the regulation of bone remodeling (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499879/
Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities (full–2012) http://rstb.royalsocietypublishing.org/content/367/1607/3353.full?sid=1569c370-cd5c-4358-89ff-857201f5e069
Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with up-regulation of CB1 and CB2 (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22366523
THE CO-EXPRESSION OF THE ENDOCANNABINOID SYSTEM AND THE RANK/RANKL SIGNALLING PATH-WAY IN HUMAN BONE AND OSTEOCLAST CULTURE (abst–2012) http://www.bjjprocs.boneandjoint.org.uk/content/94-B/SUPP_XVIII/7.abstract?maxtoshow=&hits=25&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=130&sortspec=date&resourcetype=HWCIT
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Cannabinoids: novel therapies for arthritis? (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22530636
Combined deficiency of the CB1 and CB2 receptors enhances peak bone mass by inhibiting osteoclast differentiation but increases age-related bone loss by promoting adipocyte differentiation and reducing osteoblast differentiation (abst–2012) http://www.thebonejournal.com/article/S8756-3282%2812%2900153-6/abstract
Magnolol Ameliorates Ligature-Induced Periodontitis in Rats and Osteoclastogenesis: In Vivo and In Vitro Study (full–2013) http://www.hindawi.com/journals/ecam/2013/634095/
Cannabinoid WIN-55,212-2 Mesylate Inhibits Interleukin-1β Induced Matrix Metallo-proteinase and Tissue Inhibitor of Matrix Metalloproteinase Expression in Human Chondrocytes (full–2013) http://www.oarsijournal.com/article/S1063-4584%2813%2900999-0/fulltext
The cannabinoid receptor type 1 is essential for mesenchymal stem cell survival and differentiation: implications for bone health (full–2013) http://www.hindawi.com/journals/sci/2013/796715/
The 17-β-oestradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23142558
Increase of mesenchymal stem cell migration by Cannabidiol via activation of p42/44 MAPK (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24304686
Modulation of Strain-Specific Differences in Gene Expression by Cannabinoid Type 2 Receptor Deficiency (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24370613
New insights into the physiology of bone regulation: the role of neuro-hormones (full–2014) http://www.biomed.cas.cz/physiolres/pdf/prepress/932668.pdf
Iron overload causes osteoporosis in Thalassemia Major patients through interaction with TRPV1 channels (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258755/
Therapeutical Potential of CB2 Receptors in Immune-Related Diseases (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24720538
Cannabinoid receptor expression in femora and tibiae of C57/blk6 mice fed DHA and relationship to bone ash and BMC (bone mineral content) (abst–2014) http://www.fasebj.org/content/28/1_Supplement/1032.2.abstract?sid=467bb529-0ecc-4ddc-af27-3f56f520a102
Type-2 cannabinoid receptor regulates proliferation, apoptosis, differentiation, and OPG / RANKL ratio of MC3T3-E1 cells exposed to Titanium particles (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25292314
Genetic background modifies the effects of type 2 cannabinoid receptor deficiency on bone mass and bone turnover (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24036631
Activation of Cannabinoid Receptor 2 Enhances Osteogenic Differentiation of Bone Marrow Derived Mesenchymal Stem Cells (full–2015) http://www.hindawi.com/journals/bmri/2015/874982/
Bone cell-autonomous contribution of type 2 cannabinoid receptor to breast cancer induced osteolysis (full–2015) http://www.jbc.org/content/early/2015/07/20/jbc.M115.649608.long
Cannabis – the Israeli perspective (full–2015) http://www.degruyter.com/view/j/jbcpp.ahead-of-print/jbcpp-2015-0091/jbcpp-2015-0091.xml
The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on
Human Osteoblast Proliferation and Differentiation (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136546
The skeletal endocannabinoid system: clinical and experimental insights (full–2015) http://www.degruyter.com/view/j/jbcpp.ahead-of-print/jbcpp-2015-0073/jbcpp-2015-0073.xml
A synergistic interaction of 17-β-estradiol with specific cannabinoid receptor type 2 antagonist/inverse agonist on proliferation activity in primary human osteoblasts (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487012/
Effects of deleting cannabinoid receptor-2 on mechanical and material properties of cortical and trabecular bone (full–2015) http://www.tandfonline.com/doi/full/10.1080/23311916.2014.1001015
Cannabidiol, a Major Non-Psychotrophic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25801536
CB1 cannabinoid receptors mediate endochondral skeletal growth attenuation by Δ9-tetrahydrocannabinol (full–2015) http://onlinelibrary.wiley.com/doi/10.1111/nyas.12642/full
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Dose-response estrogen promotes osteogenic differentiation via GPR40 (FFAR1) in murine BMMSCs (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25576830
Osseous Characteristics of Mice Lacking Cannabinoid Receptor 2 after Pulp Exposure (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25773059
CB2 and TRPV1 receptors oppositely modulate in vitro human osteoblast activity (abst–2015) http://www.sciencedirect.com/science/article/pii/S1043661815001243
The brain in bone and fuel metabolism (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26545334
Effects of bioactive fatty acid amide derivatives in zebrafish scale model of bone metabolism and disease (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26707833
A collaboration investigating endocannabinoid signalling in brain and bone (full–2016) http://www.degruyter.com/view/j/jbcpp.ahead-of-print/jbcpp-2015-0125/jbcpp-2015-0125.xml
The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB2, TRPV1, TRPA1 and yet unidentified receptor targets (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858820/
Exploring the Bone Proteome to Help Explain Altered Bone Remodeling and Preservation of Bone Architecture and Strength in Hibernating Marmots (full–2016) http://www.journals.uchicago.edu/doi/full/10.1086/687413 Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity (full–2016) http://journal.frontiersin.org/article/10.3389/fphar.2016.00503/full
Cannabinoid WIN-55,212-2 mesylate inhibits ADAMTS-4 activity in human osteoarthritic articular chondrocytes by inhibiting expression of syndecan-1 (link to PDF-2016) https://www.spandidos-publications.com/10.3892/mmr.2016.5137
Anti-Inflammatory and Osteoprotective Effects of Cannabinoid-2 Receptor Agonist Hu- 308 in a Rat Model of Lipopolysaccharide-Induced Periodontitis (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26846967
Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1-/-) mice (abst–2016) http://www.medengphys.com/article/S1350-4533(16)30148-5/abstract
Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets (abst–2016) http://www.sciencedirect.com/science/article/pii/S1388198116302013
The Central Nervous System and Bone Metabolism: An Evolving Story (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27501818
The endocannabinoid system and bone (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27734700
Overlapping molecular pathways between cannabinoid receptors type 1 and 2 and estrogens/androgens on the periphery and their involvement in the pathogenesis of common diseases (Review) (abst–2016) https://www.spandidos-publications.com/10.3892/ijmm.2016.2779
PKCβII-mediated cross-talk of TRPV1/CB2 modulates the glucocorticoid-induced osteoclast overactivity (abst–2016) http://www.sciencedirect.com/science/article/pii/S1043661816310994
The role of mifamurtide in chemotherapy-induced osteoporosis of children with osteosarcoma (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27993113
Protective effects of trans-caryophyllene on maintaining osteoblast function (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/28026135
β-Caryophyllene promotes osteoblastic mineralization, and suppresses osteoclastogenesis and adipogenesis in mouse bone marrow cultures in vitro (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/28105093


OVARIAN CYSTS
Lack of association between C385A functional polymorphism of the fatty acid amide hydrolase gene and polycystic ovary syndrome (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23616186
Relationship between leptin receptor and polycystic ovary syndrome (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23769971
Cannabinoid receptor 1 gene polymorphisms and nonalcoholic Fatty liver disease in women with polycystic ovary syndrome and in healthy controls (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127238/
Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25093427
Endocannabinoid system activation may be associated with insulin resistance in women with polycystic ovary syndrome (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25935491
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Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27651218
Decreased expression of fatty acid amide hydrolase in women with polycystic ovary syndrome (abst–2017) https://www.ncbi.nlm.nih.gov/pubmed/28132572


OVERDOSES on CANNABINOIDS
Cannabis Overdose (case report – undated) http://cannabisclinicians.org/view-all-case-reports/entry/96/?pagenum=3
Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada) (full–2010) http://www.hc-sc.gc.ca/dhp-mps/marihuana/med/infoprof-eng.php
Accidental cannabis poisoning in children: report of four cases in a tertiary care center from southern Spain (abst–2011) http://www.unboundmedicine.com/medline/ebm/record/21283933/abstract/%5BAccidental_cannabis_poisoning_in_children:_report_of_four_cases_in_a_tertiary_care_center_from_southern_Spain%5D_
Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine (abst–2011) http://www.unboundmedicine.com/medline/ebm/record/20634020/abstract/Prolonged_coma_in_a_child_due_to_hashish_ingestion_with_quantitation_of_THC_metabolites_in_urine_
Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature (full–2012) http://www.harmreductionjournal.com/content/9/1/7
Acute cannabis poisoning in a 10-month-old infant (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22652516
Recreational use and overdose of ingested processed cannabis (Majoon Birjandi) in the eastern Iran (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22751199
Pregnenolone can protect the brain from cannabis intoxication (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057431/
Intoxication from accidental ingestion of hashish: Analysis of eight cases (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25466782
A cannabinoid-intoxicated child treated with dexmedetomidine: a case report (full–2015) http://www.jmedicalcasereports.com/content/9/1/152
Notes from the Field: Death Following Ingestion of an Edible Marijuana Product – Colorado, March 2014 (full–2015) http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6428a6.htm
A non-classical cannabinoid syndrome (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25567676
Sudden onset unexplained encephalopathy in infants: think of cannabis intoxication (abst–2015) http://link.springer.com/article/10.1007/s00431-015-2639-9
Merck Manual – Marijuana (Cannabis) Professional version (full–2016) http://www.merckmanuals.com/professional/special-subjects/recreational-drugs-and-intoxicants/marijuanacannabis
Merck Manual – Marijuana (Cannabis) Consumer version (full–2016) http://www.merckmanuals.com/home/special-subjects/recreational-drugs-and-intoxicants/marijuana Evidence for Medicinal Use of Cannabis (article–2016) http://www.physio-pedia.com/Evidence_for_Medicinal_Use_of_Cannabis
“Those edibles hit hard”: Exploration of Twitter data on cannabis edibles in the U.S. (abst–2016) http://www.drugandalcoholdependence.com/article/S0376-8716%2816%2930056-4/abstract Clinical Effects of Synthetic Cannabinoid Receptor Agonists Compared with Marijuana in Emergency Department Patients with Acute Drug Overdose (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27255136
Marijuana Misadventures in Children: Exploration of a Dose-Response Relationship and Summary of Clinical Effects and Outcomes (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27050740
Accidental cannabis poisoning in the elderly (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27900531
Occupational transdermal poisoning with synthetic cannabinoid cumyl-PINACA (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/28084855
Storage and disposal of medical cannabis among patients with cancer: Assessing the risk of diversion and unintentional digestion (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27420392
Tasty THC: Promises and Challenges of Cannabis Edibles (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/28127591


OVERDOSE PREVENTION-OPIATE/OPIOID
Cannabis in Palliative Medicine: Improving Care and Reducing Opioid-Related Morbidity (link to download-2011) http://ajh.sagepub.com/content/28/5/297
Cannabis as an adjunct to or substitute for opiates in the treatment of chronic pain (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22880540
Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742578/
Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States, 1999-2010 (full–2014) http://archinte.jamanetwork.com/article.aspx?articleid=1898878
The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation : a case report (full–2015) http://link.springer.com/article/10.1007%2Fs12630-015-0525-6
Veterans Health Administration Policy on Cannabis as an Adjunct to Pain Treatment with Opiates (article–2015) http://journalofethics.ama-assn.org/2015/06/pfor2-1506.html
Is cannabis use associated with less opioid use among people who inject drugs? (abst–2015) http://www.drugandalcoholdependence.com/article/S0376-8716(15)00250-1/abstract Opioids Out, Cannabis In (1st page–2016) http://jamanetwork.com/journals/jama/article-abstract/2576617
Medical cannabis associated with decreased opiate medication use in retrospective crosssectional survey of chronic pain patients (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27001005
Problematic Use of Prescription Opioids and Medicinal Cannabis Among Patients Suffering from Chronic Pain (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27346885


OVERVIEWS
Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada) (full–2010) http://www.hc-sc.gc.ca/dhp-mps/marihuana/med/infoprof-eng.php
Cannabis and Its Derivatives: Review of Medical Use (full–2011) http://www.jabfm.org/cgi/content/full/24/4/452
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
Global Commission Drug Report (links to full in various languages–2011) http://www.globalcommissionondrugs.org/Report
Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed (full–2011) (deceptive title) http://www.hanf-info.ch/info/en/IMG/pdf/EIHA-11-05-31_EIHA-Statement_on_THC_in_feed.pdf
The endocannabinoid system: an overview (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303140/
The Therapeutic Potential of Cannabis and Cannabinoids (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442177/
Blurred Boundaries: The Therapeutics and Politics of Medical Marijuana (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538401/
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2012 Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064474/
The Legalization of Marijuana in Colorado: The Impact. Rocky Mountain HIDTA. The Impact (full-2014) http://www.rmhidta.org/html/August%202014%20Legalization%20of%20MJ%20in%20Colorado%20the%20Impact.pdf
Report on Medical Cannabis Research History- What the Science Says (article–2014) http://www.safeaccessnow.org/medical_cannabis_research_what_does_the_evidence_say
An Overview of Products and Bias in Research (full–2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604179/
Cannabis conundrum: Evidence of harm?: Opposition to marijuana use is often rooted in arguments about the drug’s harm to children and adults, but the scientific evidence is seldom clear-cut (Part 1 of 2) (article-2015) http://onlinelibrary.wiley.com/doi/10.1002/cncy.21516/full
Medical marijuana: Hints of headway? Despite a conflicted regulatory landscape, support for medical marijuana is growing amid increasing evidence of potential benefits (Part 2 of 2) (article-2015) http://onlinelibrary.wiley.com/doi/10.1002/cncy.21524/full
Endocannabinoids (article–2015) http://emedicine.medscape.com/article/1361971-overview#showall
Marijuana Legalization and Decriminalization Overview (article-2015) http://criminal.findlaw.com/criminal-charges/marijuana-legalization-and-decriminalizationoverview.html#sthash.yjNdUJjQ.dpuf
Cannabis in the United States (report–2016) http://self.gutenberg.org/article/WHEBN0020566488/Cannabis%20in%20the%20United%20States
Cannabinoids in the Brain: New Vistas on an Old Dilemma (article–2016) http://www.hindawi.com/journals/np/2016/9146713/