JK (2010-2018)

STUDIES ON CONDITIONS and RELATED ARTICLES 2010-2018

+Studies in 2000-2009 List
*Studies in Pre-2000 List
>Information in Another Section

JOINT REPLACEMENT
JOINT STIFFNESS
KIDNEYS +


JOINT REPLACEMENT
Effects of a Cannabinoid Receptor 2 Selective Antagonist on the Inflammatory Reaction
to Titanium Particles In Vivo and In Vitro (abst–2010)  http://journals.sagepub.com/doi/pdf/10.1177/147323001003800616
Type-2 cannabinoid receptor regulates proliferation, apoptosis, differentiation, and
OPG/RANKL ratio of MC3T3-E1 cells exposed to Titanium particles (abst–2014)  http://www.ncbi.nlm.nih.gov/pubmed/25292314
Endocannabinoids and acute pain after total knee arthroplasty (full–2015)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299927/
Plasma endocannabinoid behaviour in total knee and hip arthroplasty (abst–2016)  https://www.ncbi.nlm.nih.gov/pubmed/28078867


JOINT STIFFNESS
Increased expression of type 1 cannabinoid (CB1) receptor among patients with rotator  cuff lesions and shoulder stiffness (abst–2017)  https://www.ncbi.nlm.nih.gov/pubmed/29108858


KIDNEYS +
Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy (full–2010) http://diabetes.diabetesjournals.org/content/59/4/1046.full?sid=0bc8e3fa-5275-4b19-8acc-4aec5dfac384
Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869084/?tool=pubmed
Expression of cannabinoid receptors in human kidney (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20607655
Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682269/
Cannabinoid CB1 receptor expression in relation to visceral adipose depots,  endocannabinoid levels, microvascular damage, and the presence of the Cnr1 A3813G  variant in humans (abst–2010) http://www.metabolismjournal.com/article/S0026-0495(09)00408-9/abstract
Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity glycine transporter subtype 1 inhibitor and GPR55 agonist (full–2011) http://jpet.aspetjournals.org/content/337/1/236.long

Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161308/
Is there a legitimate role for the therapeutic use of cannabinoids for symptom management in chronic kidney disease? (full–2011) http://www.jpsmjournal.com/article/S0885-3924%2810%2900979-6/fulltext
Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21294251
Cannabinoid hyperemesis syndrome inducing acute prerenal failure and electrolyte disturbance (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21877303
β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312970/
AKI Associated with Synthetic Cannabinoids: A Case Series (full–2012) http://www.ncbi.nlm.nih.gov/pubmed/23243266
Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities (full–2012) http://rstb.royalsocietypublishing.org/content/367/1607/3353.full?sid=1569c370-cd5c-4358-89ff-857201f5e069
Cannabidiol treatment ameliorates ischemia/reperfusion renal injury in rats (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22877651
Palmitoylethanolamide reduces early renal dysfunction and injury caused by experimental ischemia and reperfusion in mice (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22772472
Cannabinoid Receptor 2 Expression in Human Proximal Tubule Cells is Regulated by Albumin Independent of ERK1/2 Signaling (full–2013) http://www.karger.com/Article/Pdf/354529
Common polymorphism in the cannabinoid type 1 receptor gene (CNR1) is associated with microvascular complications in type 2 diabetes (full–2013) http://www.jdcjournal.com/article/S1056-8727%2813%2900199-2/fulltext
First Metabolic Profile of XLR-11, a Novel Synthetic Cannabinoid, Obtained by Using Human Hepatocytes and High-Resolution Mass Spectrometry (full–2013) http://www.clinchem.org/content/59/11/1638.long
Acute Kidney Injury Associated with Synthetic Cannabinoid Use – Multiple States, 2012 (report–2013) http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6206a1.htm
Cannabinoid hyperemesis acute renal failure: a common sequela of cannabinoid
hyperemesis syndrome (1st page–2013) http://www.ajemjournal.com/article/S0735-6757%2813%2900850-4/abstract
Cannabinoid Receptors as Therapeutic Targets for Dialysis-Induced Peritoneal Fibrosis (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23296044

top
Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy (full–2014) http://www.pnas.org/content/111/50/E5420.full?sid=66cd362f-ac53-47ba-920e-b7dae50940a2
Activation of G-protein-coupled receptor 40 attenuates the cisplatin-induced apoptosis of human renal proximal tubule epithelial cells (full–2014) http://www.spandidos-publications.com/ijmm/34/4/1117
Nephrotoxic Effects of Common and Emerging Drugs of Abuse (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220747/
Evaluation of the pharmacokinetics and safety of a single oral dose of fasiglifam in subjects with normal or varying degrees of impaired renal function (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269813/
Nephrotoxic effects of designer drugs: synthetic is not better! (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24662435
Therapeutic Potential of Cannabinoids in Counteracting Chemotherapy-induced Adverse Effects: An Exploratory Review (full–2014) http://onlinelibrary.wiley.com/doi/10.1002/ptr.5265/full
Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24827776
Acute kidney injury associated with smoking synthetic cannabinoid (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25089722
Severe rhabdomyolysis and intracranial hemorrhage associated with synthetic cannabinoid: a case report (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25179201
A case of acute cerebral ischemia following inhalation of a synthetic cannabinoid (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25241766
Elevated CB1 and GPR55 receptor expression in proximal tubule cells and whole kidney exposed to diabetic conditions (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25545857
Targeting inflammation: new therapeutic approaches in chronic kidney disease (CKD) (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24602801
Fatty Acid-Binding Protein 4 (FABP4): Pathophysiological Insights and Potent Clinical Biomarker of Metabolic and Cardiovascular Diseases (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315049/
Overexpression of g-protein-coupled receptor 40 enhances the mitogenic response to epoxyeicosatrienoic acids (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113130
Rhabdomyolysis and Acute Kidney Injury Requiring Dialysis as a Result of Concomitant Use of Atypical Neuroleptics and Synthetic Cannabinoids (full–2015) http://www.hindawi.com/journals/crin/2015/235982/
Synthetic cannabinoids and acute kidney injury (full–2015)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569229/
A New Differential Diagnosis: Synthetic Cannabinoids-Associated Acute Renal Failure  (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666428/
Role of the Endocannabinoid System in Diabetes and Diabetic Complications (full–2015)  http://onlinelibrary.wiley.com/doi/10.1111/bph.13226/full
Renal effects of chronic pharmacological manipulation of CB2 receptors in rats with diet induced obesity (full–2015)  http://onlinelibrary.wiley.com/enhanced/doi/10.1111/bph.13056
Chronic administration with AM251 improves albuminuria and renal tubular structure in obese rats (full–2015) http://joe.endocrinology-journals.org/content/225/2/113.long
The endocannabinoid system in renal cells: regulation of Na+ transport by CB1 receptors
through distinct cell signalling pathways (full – 2015)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594267/
Urinary early kidney injury molecules in children with beta-thalassemia major (full–2015) http://www.tandfonline.com/doi/full/10.3109/0886022X.2015.1007871
The emerging role of the endocannabinoid system in the pathogenesis and treatment of
kidney diseases (full–2015) http://www.degruyter.com/view/j/jbcpp.ahead-of-print/jbcpp-2015-0055/jbcpp-2015-0055.xml
Novel case of synthetic cannabinoid hyperemesis resulting in rhabdomyolysis and acute  renal failure (1st page–2015) http://www.ajemjournal.com/article/S0735-6757%2815%2900743-3/abstract
Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists As Potential  Treatment for Inflammatory Kidney Diseases (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569229/

High-throughput salting-out assisted liquid-liquid extraction with acetonitrile for the determination of anandamide in plasma of hemodialysis patients with liquid chromatography tandem mass spectrometry (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25622579
The effect of endocannabinoid system in ischemia-reperfusion injury: a friend or a foe? (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25936364
Synthetic Cannabinoids (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26132518

Enhanced vasorelaxation effect of endogenous anandamide on thoracic aorta in renal vascular hypertension rats (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26173564
Therapy with a Selective Cannabinoid Receptor Type 2 Agonist Limits Albuminuria and Renal Injury in Mice with Type 2 Diabetic Nephropathy (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26646377
Adelmidrol increases the endogenous concentrations of palmitoylethanolamide in canine keratinocytes and down-regulates an inflammatory reaction in an in vitro model of contact allergic dermatitis (abst-2015) http://www.sciencedirect.com/science/article/pii/S1090023315004712
Inflammation in diabetic nephropathy: moving toward clinical biomarkers and targets for treatment (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25273317
Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists As Potential  Treatment for Inflammatory Kidney Diseases (abst–2015)  http://www.ncbi.nlm.nih.gov/pubmed/26228928
“Spice” Can Really Heat Things Up (abst–2015)  http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4600
New insights into the yin and yang of the endocannabinoid system in health and disease (full–2016) http://onlinelibrary.wiley.com/doi/10.1111/bph.13451/full

Uremic Pruritus Is Not Associated with Endocannabinoid Receptor 1 Gene Polymorphisms (full–2016) http://www.hindawi.com/journals/bmri/2016/3567527/
Protective Action of Anandamide and its COX-2 Metabolite against L-Homocysteine induced NLRP3 Inflammasome Activation and Injury in Podocytes (full–2016) http://jpet.aspetjournals.org/content/early/2016/05/10/jpet.116.233239.long
Cannabinoid Hyperemesis Syndrome Associated With Compulsive Showering and Acute Kidney Injury (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874760/
Synthetic Cannabinoid Induced acute Tubulointerstitial Nephritis and Uveitis Syndrome: A Case Report and Review of Literature (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948465/
AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells (full–2016) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167848
Association between plasma endocannabinoids and appetite in hemodialysis patients: A pilot study (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27333956
Age-specific influences of chronic administration of the fatty acid amide hydrolase  inhibitor URB597 on cardiovascular parameters and organ hypertrophy in DOCA-salt
hypertensive rats (abst–2016)  http://www.sciencedirect.com/science/article/pii/S1734114015003412
Dangerous drugs: products containing synthetic chemicals (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26915246
Role of cannabinoid receptors in renal diseases (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26968477

Toxicological impact of JWH-018 and its phase I metabolite N-(3-hydroxypentyl) on human cell lines (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27054591
Anandamide and its metabolites: what are their roles in the kidney? (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27100705
A multicenter retrospective survey of poisoning after consumption of products containing novel psychoactive substances from 2013 to 2014 in Japan (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27314752
Cannabinoid receptors in the kidney (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27367912
Repeated Thrombosis After Synthetic Cannabinoid Use (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27595371
Acute Effects of Synthetic Cannabinoids: Update 2015 (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27715709
Overactivation of cannabinoid receptor type 1 in rostral ventrolateral medulla promotes cardiovascular responses in spontaneously hypertensive rats (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27861247
LACTIC ACIDOSIS: A RARE MANIFESTATION OF SYNTHETIC MARIJUANA INTOXICATION (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27159480
Synthetic cannabinoids in the kidneys (full–2017) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017000100010&lng=en&nrm=iso&tlng=en
Targeting cannabinoid signaling for peritoneal dialysis-induced oxidative stress and  fibrosis (full–2017) http://www.wjgnet.com/2220-6124/full/v6/i3/111.htm
Thrombotic microangiopathy associated with synthetic cannabinoid receptor agonists  (full–2017) http://sci.amegroups.com/article/view/15022/15166
Bilateral renal cortical necrosis associated with smoking synthetic cannabinoids (full–2017) https://www.wjgnet.com/2307-8960/full/v5/i6/234.htm
Increased Renal 2-Arachidonoylglycerol Level Is Associated with Improved Renal  Function in a Mouse Model of Acute Kidney Injury (full–2017)  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531066/
Spice-y Kidney Failure: A Case Report and Systematic Review of Acute Kidney Injury  Attributable to the Use of Synthetic Cannabis (full–2017)  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424589/
Redox system and phospholipid metabolism in the kidney of hypertensive rats after  FAAH inhibitor URB597 administration (full–2017)  http://www.sciencedirect.com/science/article/pii/S2213231717308303
Thermolytic degradation of synthetic cannabinoids: chemical exposures and  pharmacological consequences (link to download–2017)  http://jpet.aspetjournals.org/content/early/2017/01/13/jpet.116.238717.long
Selective cannabinoid 2 receptor stimulation reduces tubular epithelial cell damage  following renal ischemia-reperfusion injury (link to download–2017)  http://jpet.aspetjournals.org/content/early/2017/11/29/jpet.117.245522.long
Dual therapy targeting the endocannabinoid system prevents experimental diabetic
nephropathy (abst–2017) https://www.ncbi.nlm.nih.gov/pubmed/28387811
Cannabinoids and the Kidney: Effects in Health and Disease (abst–2017)  https://www.ncbi.nlm.nih.gov/pubmed/28747360
Stimulation of diuresis and natriuresis by renomedullary infusion of a dual inhibitor of  fatty acid amide hydrolase and monoacylglycerol lipase (abst–2017)  https://www.ncbi.nlm.nih.gov/pubmed/28768662
Marijuana and Cannabinoids in ESRD and Earlier Stages of CKD (abst–2017)  https://www.ncbi.nlm.nih.gov/pubmed/28811049
Proximal Tubular Cannabinoid-1 Receptor Regulates Obesity-Induced CKD (abst–2017)  https://www.ncbi.nlm.nih.gov/pubmed/28860163
Synthetic cannabinoid “Black Mamba” infidelity in patients presenting for emergency  stabilization in Colorado: a P SCAN Cohort (abst–2017)  https://www.ncbi.nlm.nih.gov/pubmed/28862050
The role of cannabinoid receptors in renal diseases (abst–2017)  https://www.ncbi.nlm.nih.gov/pubmed/28901271
Cannabinoids Regulate the Diameter of Pericyte-Containing Retinal Capillaries in Rats  (abst–2017) https://www.ncbi.nlm.nih.gov/pubmed/29059679
Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular  dysfunction in a mouse model of diabetic nephropathy (abst–2017)  https://www.ncbi.nlm.nih.gov/pubmed/29106063
Indoxyl sulfate upregulates the cannabinoid type 1 receptor gene via an ATF3/c-Jun  complex-mediated signaling pathway in the model of uremic cardiomyopathy (abst–2017) http://www.internationaljournalofcardiology.com/article/S0167-5273(17)34436-4/fulltext
Non-clinical toxicity of β-caryophyllene, a dietary cannabinoid: Absence of adverse  effects in female Swiss mice (abst–2017)  https://www.sciencedirect.com/science/article/pii/S0273230017304014?via%3Dihub
The therapeutic potential of targeting the peripheral endocannabinoid/CB1 receptor  system (abst–2018) http://www.ejinme.com/article/S0953-6205(18)30009-8/fulltext
Cannabinoid Receptors in Diabetic Kidney Disease (abst–2018)  https://link.springer.com/article/10.1007%2Fs11892-018-0975-7
top


Advertisements