F (2010-2017)

STUDIES ON CONDITIONS and RELATED ARTICLES 2010-2017

+Studies in 2000-2009 List
*Studies in Pre-2000 List

FAMILIAL MEDITERRANEAN FEVER  (See Pre-2000 List)
FASTING/FOOD/WATER DEPRIVATION and the ENDOCANNABINOID SYSTEM +
FERTILITY/SEXUAL FUNCTION*+
FETAL ALCOHOL SPECTRUM DISORDER
FEVER/TEMPERATURE CONTROL*+
FIBROMYALGIA +
FLU/INFLUENZA +
FRAGILE X SYNDROME (See Also AUTISM)


FASTING/FOOD/WATER DEPRIVATION and the ENDOCANNABINOID SYSTEM
Plasma anandamide and other N-acylethanolamines are correlated with their corresponding free fatty acid levels under both fasting and non-fasting conditions in women (full–2010) http://www.nutritionandmetabolism.com/content/7/1/49
Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients with Non-Constipated Irritable Bowel Syndrome (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202649/
TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats (full–2011) http://jpet.aspetjournals.org/content/339/1/228.long
Effect of rimonabant on oesophageal motor function in man (full-2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2011.04576.x/full
Plasticity in vagal afferent neurones during feeding and fasting: mechanisms and significance (abst-2011) http://www.ncbi.nlm.nih.gov/pubmed/21062423
The effects of fasting duration on gastric emptying in man, an exploration of the role of the endocannabinoid system and inter-individual responsiveness (full–2012) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2012.01954.x/full
Fasting induces CART down-regulation in the zebrafish nervous system in a cannabinoid receptor 1-dependent manner (full-2013) http://press.endocrine.org/doi/full/10.1210/me.2011-1180
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Can Physical Exercise or Food Deprivation Cause Release of Fat-Stored Cannabinoids? (full-2014) http://onlinelibrary.wiley.com/doi/10.1111/bcpt.12235/full
Involvement of the cannabinoid CB1 receptor in modulation of dopamine output in the prefrontal cortex associated with food restriction in rats (full–2014) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092224
Role of corticosterone in the murine enteric nervous system during fasting (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25214399
Fasting and exercise increase plasma cannabinoid levels in THC pre-treated rats: an examination of behavioural consequences (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24696079
Quantitative analysis of performance on a progressive-ratio schedule: effects of reinforcer type, food deprivation and acute treatment with Δ9-tetrahydrocannabinol (THC) (full–2015) http://www.sciencedirect.com/science/article/pii/S037663571500042X
Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26290104
Type 1 cannabinoid receptor modulates water deprivation-induced homeostatic responses (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26468265
Physiological roles for the subfornical organ – A dynamic transcriptome shaped by autonomic state (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26227400
Enhanced Glutamatergic Synaptic Plasticity in the Hippocampal CA1 Field of Food Restricted Rats: Involvement of CB1 Receptors (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26354043
CB1 receptors into the Prelimbic Cortex modulate food intake in rats (abst-2015) http://www.fasebj.org/content/29/1_Supplement/655.1.abstract?sid=edf921ac-0690-4aa6-ac81-0546314dd384
Circulating Endocannabinoids and Insulin Resistance in Patients with Obstructive Sleep Apnea (full–2016) http://www.hindawi.com/journals/bmri/2016/9782031/ Docosahexaenoic acid-supplementation prior to fasting prevents muscle atrophy in mice (full–2016) http://onlinelibrary.wiley.com/doi/10.1002/jcsm.12103/full
A role of CB1R in inducing θ-rhythm coordination between the gustatory and gastrointestinal insula (full–2016) http://www.nature.com/articles/srep32529 α/β-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility (full–2016) http://www.cell.com/cell-reports/fulltext/S2211-1247(16)31373-0 Unconventional endocannabinoid signaling governs sperm activation via sex hormone progesterone (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26989199
Association between plasma endocannabinoids and appetite in hemodialysis patients: A pilot study (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27333956
Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding (abst–2016) http://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.6b01482


FERTILITY/SEXUAL FUNCTION
Characterization of the Endocannabinoid System in Human Spermatozoa and Involvement of Transient Receptor Potential Vanilloid 1 Receptor in Their Fertilizing Ability (full–2010) http://endo.endojournals.org/content/150/10/4692.full?sid=f5b14012-9fbe-4f10-890c-386313060cf8
N-Acylethanolamine Levels and Expression of Their Metabolizing Enzymes during Pregnancy (full–2010) http://endo.endojournals.org/content/151/8/3965.full
Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction (full–2010) http://onlinelibrary.wiley.com/doi/10.1002/ar.21042/full
Cannabinoids and Reproduction: A Lasting and Intriguing History (link to PDF–2010) http://www.mdpi.com/1424-8247/3/10/3275
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From Fertilisation to Implantation in Mammalian Pregnancy—Modulation of Early Human Reproduction by the Endocannabinoid System (link to PDF–2010) http://www.mdpi.com/1424-8247/3/9/2910
Endocannabinoids and Human Sperm Cells (link to PDF-2010) http://www.mdpi.com/1424-8247/3/10/3200
Histomorphometric evaluation of cannabinoid receptor and anandamide modulating enzyme expression in the human endometrium through the menstrual cycle (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20369362
Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/19147270
Endocannabinoids and pregnancy (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20302856
An endocannabinoid system is localized to the hypophysial pars tuberalis of Syrian hamsters and responds to photoperiodic changes (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20165884
Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037938/?tool=pubmed
Modulation of the novel cannabinoid receptor – GPR55 – during rat fetoplacental development (full–2011) http://www.placentajournal.org/article/S0143-4004%2811%2900110-X/fulltext
Endogenous Cannabinoid Production in the Rat Female Reproductive Tract Is Regulated by Changes in the Hormonal Milieu (link to PDF–2011) http://www.mdpi.com/1424-8247/4/6/933
Treatment with tetrahydrocannabinol (THC) prevents infertility in male cystic fibrosis mice (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/22865360
Effect of capacitation on the endocannabinoid system of mouse sperm (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21723369
Effects of the cannabinoid antagonist SR 141716 on sexual and motor behavior in receptive female rats (abst–2011) http://www.ncbi.nlm.nih.gov/pubmed/21848907
Differences in the endocannabinoid system of sperm from fertile and infertile men (full–2012) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0047704
Endocannabinoid signaling in female reproduction (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382454/
Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes (full–2012) http://press.endocrine.org/doi/full/10.1210/jc.2012-1780
Uncovering a role for endocannabinoid signaling in autophagy in preimplantation mouse embryos (full–2012) http://molehr.oxfordjournals.org/content/19/2/93.full
Minireview: Endocannabinoids and Gonadal Hormones: Bidirectional Interactions in Physiology and Behavior (full–2012) http://press.endocrine.org/doi/full/10.1210/en.2011-1643
Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis (full–2012) http://ajpendo.physiology.org/content/303/4/E475.long
Anandamide Induces Sperm Release from Oviductal Epithelia through Nitric Oxide Pathway in Bovines (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281848/?tool=pubmed
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The role of endocannabinoids in gonadal function and fertility along the evolutionary axis (full–2012) http://www.sciencedirect.com/science/article/pii/S0303720712000445
Long-term use of HU210 adversely affects spermatogenesis in rats by modulating the endocannabinoid system (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22435752
Anandamide Transforms Noncopulating Rats into Sexually Active Animals (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22906359
Impact of reference gene selection for type 2 cannabinoid receptor gene expression studies in human spermatozoa (abst–2012) http://onlinelibrary.wiley.com/doi/10.1111/and.12006/abstract
Immunity and early pregnancy events: are endocannabinoids the missing link? (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/23177537
Impact of reference gene selection for type 2 cannabinoid receptor gene expression studies in human spermatozoa (abst–2012) http://onlinelibrary.wiley.com/doi/10.1111/and.12006/abstract
Implantation failure in mice with a disruption in Phospholipase C beta 1 gene: lack of embryonic attachment, aberrant steroid hormone signalling and defective endocannabinoid metabolism (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632219/
Anandamide Levels Fluctuate in the Bovine Oviduct during the Oestrous Cycle (full–2013) http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0072521
Embryonic diapause in humans: time to consider? (full–2013) http://www.rbej.com/content/11/1/92
Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction (full–2013) http://www.hindawi.com/journals/ije/2013/941237/
Estrogens and Spermiogenesis: New Insights from Type 1 Cannabinoid Receptor Knockout Mice (full–2013) http://www.hindawi.com/journals/ije/2013/501350/
Endocannabinoids as markers of sperm quality: hot spots (full–2013) http://www.frontiersin.org/Journal/10.3389/fendo.2013.00169/full
Brain Levels of Prostaglandins, Endocannabinoids, and Related Lipids Are Affected by Mating Strategies (full–2013) http://www.hindawi.com/journals/ije/2013/436252/
The Endocannabinoid System and Spermatogenesis (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864102/
Low 17beta-Estradiol Levels in Cnr1 Knock-Out Mice Affect Spermatid Chromatin Remodeling by Interfering with Chromatin Reorganization (full–2013) http://www.biolreprod.org/content/88/6/152.long
Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia (full–2013) http://humrep.oxfordjournals.org/content/28/8/2058.long
Elevated Anandamide and Related N-Acylethanolamine Levels Occur in the Peripheral Blood of Women With Ectopic Pregnancy and Are Mirrored by Changes in Peripheral Fatty Acid Amide Hydrolase Activity (full–2013) http://press.endocrine.org/doi/full/10.1210/jc.2012-3390
Synthetic cannabinoids and potential reproductive consequences (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823745/
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Of mice and (wo)men: factors influencing successful implantation including endocannabinoids (full–2013) http://humupd.oxfordjournals.org/content/20/3/415.long
Sexuality, heart and chocolate (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23547364
Effectiveness of vaginal adelmidrol for treating pelvic visceral discomforts and anxiety: a prospective observational study (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24051946
Endocannabinoids are Involved in Male Vertebrate Reproduction: Regulatory Mechanisms at Central and Gonadal Level (full–2014) http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00054/full
A role for endocannabinoids in acute stress-induced suppression of the hypothalamic-pituitary-gonadal axis in male rats (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913894/
Increased placental expression of cannabinoid receptor 1 in preeclampsia: an observational study (full–2014) http://www.ncbi.nlm.nih.gov/pubmed/25444073
The endocannabinoid anandamide induces apoptosis in cytotrophoblast cells: Involvement of both mitochondrial and death receptor pathways (full–2014) http://www.placentajournal.org/article/S0143-4004%2814%2900823-6/fulltext
Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa (full–2014) http://onlinelibrary.wiley.com/doi/10.1111/j.2047-2927.2014.00210.x/full
Endocannabinoids as biomarkers of human reproduction (full–2014) http://humupd.oxfordjournals.org/content/20/4/501.long
The biological networks in studying cell signal transduction complexity: The examples of sperm capacitation and of endocannabinoid system (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212279/
Endocannabinoid Regulation in Human Endometrium Across the Menstrual Cycle (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527420/
Low anandamide doses facilitate male rat sexual behaviour through the activation of CB1 receptors (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24671517
Endocannabinoid signaling in mammalian ovary (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24948047
Endocannabinoid Influence on Partner Preference in Female Rats (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25042777
Activity of anandamide (AEA) metabolic enzymes in rat placental bed (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25088244
Lipidomic approach towards deciphering anandamide effects in rat decidual cell (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25535694
The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140142
Endocannabinoid signaling in female reproductive events: a potential therapeutic target? (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26126134
Endocannabinoid signaling in female reproductive events: a potential therapeutic target? (full–2015) http://www.tandfonline.com/doi/full/10.1517/14728222.2015.1062878
Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26229240
Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta (full–2015) http://www.hindawi.com/journals/mi/2015/850471/
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A role for GPR55 in human placental venous endothelial cells (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25869640
Dynamics of expression and localization of the cannabinoid system in granulosa cells during oocyte nuclear maturation (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26144572
Endocannabinoid signaling in the stress response of male and female songbirds (link to PDF–2015) http://press.endocrine.org/doi/10.1210/en.2015-1425?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&
Participation of the endocannabinoid system (ECS) in the weight-gain and sensitization to LPS exposure in a maternal obesity model (article–2015) http://www.placentajournal.org/article/S0143-4004%2815%2900526-3/fulltext
Type 2 cannabinoid receptor contributes to the physiological regulation of spermato-genesis (full–2015) http://www.fasebj.org/content/early/2015/12/15/fj.15-279034.long
Anandamide Reduces the Ejaculatory Threshold of Sexually Sluggish Male Rats: Possible Relevance for Human Lifelong Delayed Ejaculation Disorder (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25808995
Lipopolysaccharide-induced murine embryonic resorption involves changes in endocannabinoid profiling and alters progesterone secretion and inflammatory response by a CB1-mediated fashion (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25958042
Anandamide restricts uterine stromal differentiation and is critical for complete decidualization (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25960165
Sperm Release from the Oviductal Epithelium Depends on Ca2+ Influx Upon Activation of CB1 and TRPV1 by Anandamide (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26129689
Strain and sex differences in puberty onset and the effects of THC administration on weight gain and brain volumes (abst–2015) http://www.sciencedirect.com/science/article/pii/S0306452215006387
Biphasic effects of anandamide on behavioural responses: emphasis on copulatory behaviour (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26226145
Anandamide and Decidual Remodeling: COX-2 oxidative metabolism as a key regulator (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26335727
Anandamide acts via kisspeptin in the regulation of testicular activity of the frog, Pelophylax esculentus (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26586207
Endocannabinoid Regulation of Neuroendocrine Systems (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26638767
Progesterone and Endocannabinoid Interaction Alters Sperm Activation (full–2016) http://www.biolreprod.org/content/95/1/9.long
Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18 (full–2016) http://www.nature.com/articles/srep32255 Elevated Systemic Levels of Endocannabinoids and Related Mediators Across the Menstrual Cycle in Women With Endometriosis (full–2016) http://journals.sagepub.com/doi/full/10.1177/1933719116630414
Role of the endocannabinoid system in the control of mouse myometrium contractility during the menstrual cycle (full–2016) http://www.sciencedirect.com/science/article/pii/S0006295216304452
The endocannabinoid system in the human granulosa cell line KGN (abst–2016) http://www.sciencedirect.com/science/article/pii/S0303720716300065
The endocannabinoid system in the human granulosa cell line KGN (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26773729
Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26945481
Dynamic of expression and localization of cannabinoid-degrading enzymes FAAH and MGLL in relation to CB1 during meiotic maturation of human oocytes (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26948343
Age of Sexual Debut and Cannabis Use in the United States (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26881806
The endocannabinoid anandamide impairs in vitro decidualization of human cells (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27568210
2-arachidonoylglycerol levels are increased in leukocytospermia and correlate with seminal macrophages (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27863106
Intra-VTA anandamide infusion produces dose-based biphasic effects on male rat sexual behavior expression (abst–2016) http://www.sciencedirect.com/science/article/pii/S0091305716302258
Endocannabinoid system in sexual motivational processes: is it a novel therapeutic horizon? (abst–2016) http://www.sciencedirect.com/science/article/pii/S1043661816312385
Developmental Patterns of Adolescent Marijuana and Alcohol Use and Their Joint Association with Sexual Risk Behavior and Outcomes in Young Adulthood (abst–2017) https://www.ncbi.nlm.nih.gov/pubmed/28083726
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FETAL ALCOHOL SPECTRUM DISORDER
Reduced expression of brain cannabinoid receptor 1 (Cnr1) is coupled with an increased complementary micro-RNA (miR-26b) in a mouse model of fetal alcohol spectrum disorders (full-2014) http://www.clinicalepigeneticsjournal.com/content/5/1/14
Gene-Specific Disruption of Endocannabinoid Receptor 1 (cnr1a) by Ethanol Probably Leads to the Development of Fetal Alcohol Spectrum Disorder (FASD) Phenotypes in Japanese Rice Fish (Oryzias latipes) Embryogenesis (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25251458
Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling (full-2015) http://www.mdpi.com/2076-3425/5/4/456/htm
Prenatal exposure to recreational drugs affects global motion perception in preschool children (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652269/


FEVER/TEMPERATURE CONTROL
Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation (abst-2010) http://journals.lww.com/ccmjournal/Abstract/2010/12000/Pharmacologically_induced_hypothermia_with.2.aspx
DOSE-DEPENDENT EFFECTS ON VENTILATION AT REST INDUCED BY HIGH DOSES OF CANNABINOIDS IN RATS (abst–2010)  http://www.maneyonline.com/doi/abs/10.1179/acb.2010.115
Contribution of Hypothermia and CB(1) Receptor Activation to Protective Effects of TAK-937, a Cannabinoid Receptor Agonist, in Rat Transient MCAO Model (full-2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397930/?toolubmed
Δ9-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697741/
Chronic administration of THC prevents the behavioral effects of intermittent adolescent MDMA administration and attenuates MDMA-induced hyperthermia and neurotoxicity in rats (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189263/
Δ9-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice (full–2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697741/
Cannabinoid 1 (CB1) receptor mediates WIN55, 212-2 induced hypothermia and improved survival in a rat post-cardiac arrest model (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22289684
Determination of naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-01 in mouse blood and tissue after inhalation exposure to ‘buzz’ smoke by HPLC/MS/MS (abst–2012) http://onlinelibrary.wiley.com/doi/10.1002/bmc.2710/abstract
Dissociation of the Pharmacological Effects of THC by mTOR Blockade (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656376/
Cannabinoid (CB)1 receptors are critical for the innate immune response to TLR4 stimulation (full–2013) http://ajpregu.physiology.org/content/305/3/R224
Behavioral Responses to Acute and Sub-chronic Administration of the Synthetic Cannabinoid JWH-018 in Adult Mice Prenatally Exposed to Corticosterone (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23296549
Improved Cardiac and Neurologic Outcomes With Postresuscitation Infusion of Cannabinoid Receptor Agonist WIN55, 212-2 Depend on Hypothermia in a Rat Model of Cardiac Arrest (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/24346544
Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882055/
Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895006/
Behavioral effects of the cannabinoid CB1 receptor allosteric modulator ORG27569 in rats (full–2014) http://onlinelibrary.wiley.com/doi/10.1002/prp2.69/full
Cannabinoid Type 1 (CB1) Receptors on Sim1-Expressing Neurons Regulate Energy Expenditure in Male Mice (full–2014) http://press.endocrine.org/doi/10.1210/en.2014-1437
Cannabidiol fails to reverse hypothermia or locomotor suppression induced by Δ9-tetrahydrocannabinol in Sprague-Dawley rats (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/25425111
Cannabidiol fails to reverse hypothermia or locomotor suppression induced by Δ9- tetrahydrocannabinol in Sprague-Dawley rats (full–2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376456/
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Genetic Dissection of Behavioural and Autonomic Effects of Δ9-Tetrahydrocannabinol in Mice (full–2015) http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0050269
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors (full–2015) http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002194
Monoacylglycerol Lipase Regulates Fever Response (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134437
Hypothalamic control of brown adipose tissue thermogenesis (full–2015)
http://journal.frontiersin.org/article/10.3389/fnsys.2015.00150/full
Neural correlates of cannabidiol and Δ9-tetrahydrocannabinol interactions in mice: implications for medical cannabis (full–2015) http://onlinelibrary.wiley.com/doi/10.1111/bph.13333/full
Fever Is Mediated by Conversion of Endocannabinoid 2-Arachidonoylglycerol to Prostaglandin E2 (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26196692
Fever Is Mediated by Conversion of Endocannabinoid 2-Arachidonoylglycerol to Prostaglandin E2 (full–2015) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133663
Hyperthermia and severe rhabdomyolysis from synthetic cannabinoids (full–2015) http://www.ajemjournal.com/article/S0735-6757%2815%2900490-8/fulltext
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26668358
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition (full–2015) http://www.pnas.org/content/113/1/26.long
Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge (full–2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477849/
Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge (full–2015) http://tinyurl.com/q9w2jpw
Use of paracetamol during pregnancy and child neurological development (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25851072
JWH-018 impairs sensorimotor functions in mice (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25987201
ENP11, a potential CB1R antagonist, induces anorexia in rats (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26072692
Endocannabinoids, through opioids and prostaglandins, contribute to fever induced by key pyrogenic mediators (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26291402
“Spice” Can Really Heat Things Up (abst–2015) http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4600
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Repeated administration of phytocannabinoid Δ9-THC or synthetic cannabinoids JWH-018 and JWH-073 induces tolerance to hypothermia but not locomotor suppression in mice, and reduces CB1 receptor expression and function in a brain region-specific manner (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26361728
Role of nociceptin/orphanin FQ in thermoregulation (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25812480
Transient increase of interleukin-1β after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling (full–2016) http://www.nature.com/articles/srep21931
Case Series of Synthetic Cannabinoid Intoxication from One Toxicology Center (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899060/
Prostaglandin E2 that triggers fever is synthesized through an endocannabinoid dependent pathway (full–2016) http://www.tandfonline.com/doi/full/10.1080/23328940.2015.1130520 A Curious Case of Inhalation Fever Caused by Synthetic Cannabinoid (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917070/
Hypothermic activity of acetaminophen; involvement of GABAA receptor, theoretical and experimental studies (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923466/
Effects of Cannabidiol and Hypothermia on Short-Term Brain Damage in New-Born Piglets after Acute Hypoxia-Ischemia (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940392/
Turning Up the Heat on Endocannabinoid Signaling (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106110/
Acetaminophen Use for Fever in Children Associated with Autism Spectrum Disorder (full–2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044872/
α/β-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility (full–2016) http://www.cell.com/cell-reports/fulltext/S2211-1247(16)31373-0 Behavioral Characterization of Kappa Opioid Receptor Agonist Spiradoline and Cannabinoid Receptor Agonist CP55940 Mixtures in Rats (link to download–2016) http://jpet.aspetjournals.org/content/early/2016/11/30/jpet.116.235630.long
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26780169
Endocannabinoids, through opioids and prostaglandins, contribute to fever induced by key pyrogenic mediators (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26291402
Novel Psychoactive Substances: the pharmacology of stimulants and hallucinogens (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26985969
Pharmacological hypothermia: a potential for future stroke therapy? (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27320243
Short-term effects of cannabidiol after global hypoxia-ischemia in newborn piglets (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/27441365
Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences (link to download–2017) http://jpet.aspetjournals.org/content/early/2017/01/13/jpet.116.238717.long


FIBROMYALGIA
The Effects of Nabilone on Sleep in Fibromyalgia: Results of a Randomized Controlled Trial (full–2010) http://journals.lww.com/anesthesiaanalgesia/Fulltext/2010/02000/The_Effects_of_Nabilone_on_Sleep_in_Fibromyalgia_.56.aspx
Emerging therapies for fibromyalgia: an update (abst–2010) http://www.ncbi.nlm.nih.gov/pubmed/20486862
Cannabis Use in Patients with Fibromyalgia: Effect on Symptoms Relief and Health-Related Quality of Life (full-2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080871/?toolubmed
Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243008/
Clinical implications for cannabinoid use in the rheumatic diseases: potential for help or harm? (full-2012) http://onlinelibrary.wiley.com/doi/10.1002/art.34522/full
Association of herbal cannabis use with negative psychosocial parameters in patients with fibromyalgia (full–2012) http://onlinelibrary.wiley.com/doi/10.1002/acr.21732/full
Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System (full-2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951193/
Clinical endocannabinoid deficiency (CECD) revisited: Can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24977967
Clinical endocannabinoid deficiency (CECD) revisited: Can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? (full-2014) http://tinyurl.com/hss39v9
Fibromyalgia (abst-2014) http://www.ncbi.nlm.nih.gov/pubmed/24365316
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PROGRESS REPORT Compassionate Use of Medical Cannabis Pilot Program Act July 1, 2014 through June 30, 2015 (full–2015) http://dph.illinois.gov/sites/default/files/publications/publicationohpmmedical-cannabis-annual-report-2015.pdf
β-caryophyllene-complexed in β-cyclodextrin Produces Antihyperalgesic Activity in Animal Model for Fibromyalgia (abst–2015) http://www.fasebj.org/content/29/1_Supplement/616.4.abstract?sid=edf921ac-0690-4aa6-ac81-0546314dd384
Expression of the endocannabinoid receptors in human fascial tissue (full–2016) http://www.ejh.it/index.php/ejh/article/view/2643/2590
Cannabinoids and autoimmune diseases: A systematic review (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26876387
Nabilone for the Management of Pain (abst–2016) http://www.ncbi.nlm.nih.gov/pubmed/26923810
Medical Cannabis – another piece in the mosaic of autoimmunity? (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27859024


FLU/INFLUENZA
Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection (full–2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206470/
Palmitoylethanolamide is a new possible pharmacological treatment for the inflammation associated with trauma (abst–2012) http://www.ncbi.nlm.nih.gov/pubmed/22697514?dopt=Abstract
Δ9-tetrahydrocannabinol impairs the inflammatory response to influenza infection: role of antigen-presenting cells and the cannabinoid receptors 1 and 2 (full–2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551428/


FRAGILE X SYNDROME
Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndrome (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906112/
Abnormal mGlu 5 receptor/endocannabinoid coupling in mice lacking FMRP and BC1 RNA (full–2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055456/
Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome (full–2012) http://www.nature.com/ncomms/journal/v3/n9/full/ncomms2045.html
Pathological plasticity in fragile X syndrome (full–2012) http://www.hindawi.com/journals/np/2012/275630/
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Targeting the endocannabinoid system in the treatment of fragile X syndrome (abst–2013) http://www.ncbi.nlm.nih.gov/pubmed/23542787
New insights into the molecular pathophysiology of fragile X syndrome and therapeutic perspectives from the animal model (abst–2014) http://www.ncbi.nlm.nih.gov/pubmed/24831882
Therapeutic approaches for the future treatment of Fragile X (abst–2015) http://www.sciencedirect.com/science/article/pii/S2352154615000133
Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model (full-2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334917/
Homer Protein-Metabotropic Glutamate Receptor Binding Regulates Endocannabinoid Signaling and Affects Hyperexcitability in a Mouse Model of Fragile X Syndrome (abst-2015) http://www.ncbi.nlm.nih.gov/pubmed/25740522
Endocannabinoid-mediated improvement on a test of aversive memory in a mouse model of fragile X syndrome (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/25979787
The basolateral amygdala γ-aminobutyric acidergic system in health and disease (abst–2015) http://www.ncbi.nlm.nih.gov/pubmed/26586374
p21-activated kinase 1 restricts tonic endocannabinoid signaling in the hippocampus (full–2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907698/
Possible Therapeutic Doses of Cannabinoid Type 1 Receptor Antagonist Reverses Key Alterations in Fragile X Syndrome Mouse Model (full–2016) http://www.mdpi.com/2073-4425/7/9/56/htm Endocannabinoid signaling in social functioning: an RDoC perspective (full–2016) http://www.nature.com/tp/journal/v6/n9/full/tp2016169a.html Dissecting the signaling pathways involved in the crosstalk between mGlu5 and CB1 receptors (link to PDF–2016) http://molpharm.aspetjournals.org/content/early/2016/06/23/mol.116.104372.long Differential Adulthood Onset mGlu5 Signaling Saves Prefrontal Function in the Fragile X Mouse (abst–2016) https://www.ncbi.nlm.nih.gov/pubmed/27797833
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