Eating Disorders-Exercise 2015-2020

STUDIES ON CONDITIONS and RELATED ARTICLES 2015-2020

*Articles/Studies in Pre-2000 List
+Articles/Studies in 2000-2009 List
^Articles/Studies in 2010-2014 List
>Information in Another Section


EATING DISORDERS-GENERAL
EBOLA
ECLAMPSIA/PRE-ECLAMPSIA
ECZEMA+
EDEMA*+
>EHLERS-DANLOS SYNDROME+ (See News Articles 2010-2018)
ELECTRICAL STIMULATION
ELECTROCONVULSIVE THERAPY
EMBRYOS/FETAL DEVELOPMENT/PLACENTAL DEVELOPMENT +
ENCEPHALITIS+
ENCEPHALOMYELITIS/EAE*+
ENDOMETRIOSIS/ENDOMETRIUM+
ENDOTOXEMIA (Low-grade inflammation from circulating endotoxins)
ENERGY DRINKS

ENTOURAGE EFFECT (See PHYTOCANNABINOIDS and ENDOCANNABINOIDS)
EPIDERMOLYSIS BULLOSA
EPILEPSY/SEIZURES* (See Also EPIDIOLEX in PHYTOCANNABINOIDS)
EPSTEIN-BARR^
ESSENTIAL TREMOR (See Also News Articles 2010-2018)
ETHICS and CANNABIS
EXERCISE and the ENDOCANNABINOID SYSTEM*+


EATING DISORDERS-GENERAL
A behavioral and pharmacological characterization of palatable diet alternation in mice. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911178/
Effects of a Weight Loss Program on Metabolic Syndrome, Eating Disorders and Psychological Outcomes: Mediation by Endocannabinoids. (Switzerland) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981584/
Endocannabinoid signaling in psychiatric disorders: a review of positron emission tomography studies. (Canada/ USA) (abst – 2018) https://www.nature.com/articles/s41401-018-0081-z
Cigarette smoke during lactation in rat female progeny: Late effects on endocannabinoid and dopaminergic systems. (Brazil) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0024320519305016?via%3Dihub


EBOLA
Addressing the Complications of Ebola and Other Viral Hemorrhagic Fever Infections: Using Insights from Bacterial and Fungal Sepsis. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591006/
Cannabidiol: a potential treatment for post Ebola syndrome? (USA) (full – 2016) https://www.ijidonline.com/article/S1201-9712(16)31177-8/fulltext
Targeting Cannabinoid Signaling in the Immune System: “High”-ly Exciting Questions, Possibilities, and Challenges. (Hungary) (full – 2017) https://www.frontiersin.org/articles/10.3389/fimmu.2017.01487/full


ECLAMPSIA/PRE-ECLAMPSIA
Decreased circulating anandamide levels in preeclampsia. (USA) (link to download– 2015) https://core.ac.uk/download/pdf/78472108.pdf
[268-POS]: Placental expression of the endocannabinoid system in preeclampsia. (Hungary) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S2210778914003754
A case of cannabinoid hyperemesis syndrome with heliobacter pylori and pre-eclampsia during pregnancy. (USA) (abst – 2017) https://www.semanticscholar.org/paper/A-case-of-cannabinoid-hyperemesis-syndrome-with-and-Meurer-Chakrala/d917eded4b2ccfbceee959b1cce1be44e154bf93


ECZEMA +
Cannabis and Dr Piffard-A Century Ahead of the Curve. (USA) (abst – 2016) http://archderm.jamanetwork.com/article.aspx?articleid=2547236
The Endocannabinoid System and Its Role in Eczematous Dermatoses. (USA) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28098721
Echinacea purpurea-derived alkylamides exhibit potent anti-inflammatory effects and alleviate clinical symptoms of atopic eczema. (Hungary/ Germany) (abst – 2017) http://www.jdsjournal.com/article/S0923-1811(16)31025-8/fulltext
https://www.semanticscholar.org/paper/Echinacea-purpurea-derived-alkylamides-exhibit-and-Ol%C3%A1h-Szab%C3%B3-Papp/6b26d91f4d66896c0e5c77cf36445f5aa9a600a0
Common Allergens Prevalent in and Around Ambala, Haryana: An Intradermal Study among Patients with Asthma and Allergic Rhinitis and Atopic Dermatitis. (India) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052743/
Cannabinoids for the Treatment of Chronic Pruritus: A Review. (USA) (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31987788


EDEMA*+
Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficit. (Spain/ Germany) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454518/
A Cannabinoid Receptor 2 Agonist Prevents Thrombin-Induced Blood-Brain Barrier Damage via the Inhibition of Microglial Activation and Matrix Metalloproteinase Expression in Rats. (China) (link to PDF – 2015) https://www.researchgate.net/publication/282044189_A_Cannabinoid_Receptor_2_Agonist_Prevents_Thrombin-Induced_Blood-Brain_Barrier_Damage_via_the_Inhibition_of_Microglial_Activation_and_Matrix_Metalloproteinase_Expression_in_Rats
Minocycline Attenuates Neonatal Germinal-Matrix-Hemorrhage-Induced Neuroinflammation and Brain Edema by Activating Cannabinoid Receptor 2 (China) (link to PDF–2015) https://www.researchgate.net/publication/274398496_Minocycline_Attenuates_Neonatal_Germinal-Matrix-Hemorrhage-Induced_Neuroinflammation_and_Brain_Edema_by_Activating_Cannabinoid_Receptor_2 Cannabinoid CB2 receptor stimulation attenuates brain edema and neurological deficits in a germinal matrix hemorrhage rat model. (China) (link to download – 2015) https://www.academia.edu/20365063/Cannabinoid_CB2_receptor_stimulation_attenuates_brain_edema_and_neurological_deficits_in_a_germinal_matrix_hemorrhage_rat_model Cannabinoid receptor 2 attenuates microglial accumulation and brain injury following germinal matrix hemorrhage via ERK dephosphorylation in vivo and in vitro. (China) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0028390815001574
Cannabinoid Receptor Type 2 Agonist Attenuates Acute Neurogenic Pulmonary Edema by Preventing Neutrophil Migration after Subarachnoid Hemorrhage in Rats. (China) (abst – 2015) https://www.sciencedirect.com/science/article/pii/S0006899315000451
Mustard vesicants alter expression of the endocannabinoid system in mouse skin. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947375/
Activation of Cannabinoid Receptor 2 Attenuates Mechanical Allodynia and Neuroinflammatory Responses in a Chronic Post-Ischemic Pain Model of Complex Regional Pain Syndrome Type I in Rats. (USA/ China) (click “Alternate Sources”, then “rsdsorg” for download – 2016) https://www.semanticscholar.org/paper/Activation-of-cannabinoid-receptor-2-attenuates-and-Xu-Tang/b76958bc75f9e27fdf6bad7f451661111189e311
Cannabinoid Receptor Type 2 Agonist Attenuates Acute Neurogenic Pulmonary Edema by Preventing Neutrophil Migration after Subarachnoid Hemorrhage in Rats . (USA/ Japan) (abst – 2016) http://link.springer.com/chapter/10.1007/978-3-319-18497-5_24
Selective modulator of cannabinoid receptor type 2 reduces memory impairment and infarct size during cerebral hypoperfusion and vascular dementia. (India) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27586843
Selective modulator of cannabinoid receptor type 2 (CB2) against biochemical alterations and brain damage in chronic cerebral hypoperfusion induced vascular dementia. (India) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27599483
Endocannabinoids: A Promising Impact for Traumatic Brain Injury. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314139/
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Inflammatory Regulation by Driving Microglial M2 Polarization: Neuroprotective Effects of Cannabinoid Receptor-2 Activation in Intracerebral Hemorrhage. (China) (full – 2017) http://journal.frontiersin.org/article/10.3389/fimmu.2017.00112/full
Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization. (USA/ Italy) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767553/
An endocannabinoid uptake inhibitor from black pepper exerts pronounced anti- inflammatory effects in mice. (Mexico/ Switzerland) (link to PDF– 2017) http://pubs.acs.org/doi/abs/10.1021/acs.jafc.7b02979
Photobiomodulation Therapy Improves Acute Inflammatory Response in Mice: the Role of Cannabinoid Receptors/ATP-Sensitive K+ Channel/p38-MAPK Signalling Pathway. (Brazil) (link to PDF – 2017) https://www.researchgate.net/publication/320213560_Photobiomodulation_Therapy_Improves_Acute_Inflammatory_Response_in_Mice_the_Role_of_Cannabinoid_ReceptorsATP-Sensitive_K_Channelp38-MAPK_Signalling_Pathway
Bilateral multiple exudative retinal detachments and macular edema in a patient diagnosed with synthetic cannabinoid (Bonzai) intoxication. (Turkey) (link to PDF – 2017) https://www.researchgate.net/publication/322026415_Bilateral_multiple_exudative_retinal_detachments_and_macular_edema_in_a_patient_diagnosed_with_synthetic_cannabinoid_Bonzai_intoxication
AB-CHMINACA-induced sudden death from non-cardiogenic pulmonary edema. (Japan) (abst – 2017) https://www.semanticscholar.org/paper/AB-CHMINACA-induced-sudden-death-from-pulmonary-Maeda-Kikura-Hanajiri/e73fbbbb944c987d9d6e5d27416783c9e87fcffa
Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury. (USA) (full – 2018) https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-018-1166-9
The Endocannabinoid Reuptake Inhibitor WOBE437 Is Orally Bioavailable and Exerts Indirect Polypharmacological Effects via Different Endocannabinoid Receptors. (Mexico/ Switzerland) (full – 2018) https://www.frontiersin.org/articles/10.3389/fnmol.2018.00180/full
Cannabinoid receptor 2 agonist attenuates blood-brain barrier damage in a rat model of intracerebral hemorrhage by activating the Rac1 pathway. (China) (link to PDF – 2018) https://www.semanticscholar.org/paper/Cannabinoid-receptor-2-agonist-attenuates-barrier-a-Wang-Li/35e04419072cffd25ed128e3c8d0f3382c348543
Effect of cannabidiolic acid and ∆9-tetrahydrocannabinol on carrageenan-induced hyperalgesia and edema in a rodent model of inflammatory pain. (Canada) (link to PDF – 2018) https://www.researchgate.net/publication/327705598_Effect_of_cannabidiolic_acid_and_9-tetrahydrocannabinol_on_carrageenan-induced_hyperalgesia_and_edema_in_a_rodent_model_of_inflammatory_pain Monoacylglycerol Lipase Inhibitor is Safe when Combined with Delayed r-tPA Administration in Treatment of Stroke. (Iran) (click “rumsacir” for download – 2018) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Monoacylglycerol+Lipase+Inhibitor+is+Safe+when+Combined+with+Delayed+r-tPA+Administration+in+Treatment+of+Stroke.&btnG
A cannabinoid receptor 2 agonist reduces blood-brain barrier damage via induction of MKP-1 after intracerebral hemorrhage in rats. (China) (abst 2018) https://www.sciencedirect.com/science/article/pii/S0006899318303330?via%3Dihub
JZL184, as a monoacylglycerol lipase inhibitor, down-regulates inflammation in a cannabinoid pathway dependent manner. (Iran) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S075333221735014X
Clinical effects of reported synthetic cannabinoid exposure in patients admitted to the intensive care unit. (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/30146395
Cannabidiol As A Novel Therapeutic Strategy For Oral Inflammatory Diseases: A Review Of Current Knowledge And Future Perspectives. (Czech Republic) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31634872


ELECTRICAL STIMULATION
Endocannabinoid CB1 receptors are involved in antiepileptogenic effect of low frequency electrical stimulation during perforant path kindling in rats (Iran – abst–2018) https://www.sciencedirect.com/science/article/pii/S0920121117304291?via%3Dihub


ELECTROCONVULSIVE THERAPY*+
 Electroconvulsive therapy enhances endocannabinoids in the cerebrospinal fluid of patients with major depression: a preliminary prospective study. (Germany) (abst – 2017) https://www.semanticscholar.org/paper/Electroconvulsive-therapy-enhances-endocannabinoids-Kranaster-Hoyer/54805dc0791bf9c61590fdc9dc30b9a2f7b3ad96 Biomarkers for Antidepressant Efficacy of Electroconvulsive Therapy: An Exploratory Cerebrospinal Fluid Study. (Germany/ Sweden/ UK) (link to download – 2018) http://discovery.ucl.ac.uk/10059854/


EMBRYOS/FETAL DEVELOPMENT/PLACENTAL DEVELOPMENT+
Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling. (USA) (full – 2015) http://www.mdpi.com/2076-3425/5/4/456/htm
Preferential epithelial expression of type-1 cannabinoid receptor (CB1R) in the developing canine embryo. (Italy) (full – 2015) http://www.springerplus.com/content/4/1/804
Endocannabinoid signaling in female reproductive events: a potential therapeutic target? (Italy) (full – 2015) http://www.tandfonline.com/doi/full/10.1517/14728222.2015.1062878
Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta. (Australia) (full – 2015) http://www.hindawi.com/journals/mi/2015/850471/
Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via PGE2 and P-selectin Activity. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781665/
Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. (Sweden/ Poland/ Austria/ Italy) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653226/
Use of paracetamol during pregnancy and child neurological development. (Belgium) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1111/dmcn.12745/full
Dynamics of expression and localization of the cannabinoid system in granulosa cells during oocyte nuclear maturation. (Spain) (full – 2015) http://www.fertstert.org/article/S0015-0282(15)00440-9/fulltext
Role of the endocannabinoid system in the mechanisms involved in the LPS-induced preterm labor. (Argentina) (full – 2015) http://www.reproduction-online.org/content/150/6/463.long
Epigenetic Effects of Cannabis Exposure. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789113/
cnrip1 is a regulator of eye and neural development in Xenopus laevis. (Japan) (full – 20 15) http://onlinelibrary.wiley.com/doi/10.1111/gtc.12225/full
Dose-dependent teratogenicity of the synthetic cannabinoid CP-55,940 in mice. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912947/
Lipid abundance in zebrafish embryos is regulated by complementary actions of the Endocannabinoid System and Retinoic Acid Pathway. (Australia) (full – 2015) https://academic.oup.com/endo/article/156/10/3596/2422925
Marijuana use and pregnancy: prevalence, associated characteristics, and birth outcomes. (USA) (link to PDF – 2015) https://www.researchgate.net/publication/275215392_Marijuana_use_and_pregnancy_prevalence_associated_characteristics_and_birth_outcomes
Progesterone and anandamide in pregnancy loss. (Argentina/ USA) (download – 2015) https://www.calgarycmmc.com/Progesterone-and-anandamide-in-pregnancy-loss.pdf
Long-term consequences of perinatal and adolescent cannabinoid exposure on neural and psychological processes. (Spain) (click “researchgate” for download – 2015) https://scholar.google.com/scholar?q=Long-term+consequences+of+perinatal+and+adolescent+cannabinoid+exposure+on+neural+and+psychological+processes&hl=en&as_sdt= 0&as_vis=1&oi=scholart
Anandamide restricts uterine stromal differentiation and is critical for complete decidualization. (Portugal) (abst – 2015) https://www.semanticscholar.org/paper/Anandamide-restricts-uterine-stromal-and-is-for-Fonseca-Correia-da-Silva/aafecbb3581e3671932d45b66f561b4fe544a977

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Anandamide and Decidual Remodeling: COX-2 oxidative metabolism as a key regulator. (Portugal) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S1388198115001651
The endocannabinoid 2-arachidonoylglycerol dysregulates the synthesis of proteins by the human syncytiotrophoblast. (Portugal) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S1388198115002309
Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring. (Spain/ Germany) (full – 2016) http://journal.frontiersin.org/article/10.3389/fnbeh.2016.00208/full
Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid. (Italy) (full – 2016) http://www.nature.com/tp/journal/v6/n9/full/tp2016182a.html
Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation. (France) (full – 2016) https://academic.oup.com/cercor/article-lookup/doi/10.1093/cercor/bhw052
Exocannabinoids effect on in vitro bovine oocyte maturation via activation of AKT and ERK1/2. (Spain/ Colombia) (full – 2016) http://www.reproduction-online.org/content/152/6/603.long
Sexually-dimorphic alterations in cannabinoid receptor density depend upon prenatal/early postnatal history. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5184775/
A role for the endocannabinoid system in premature luteal regression and progesterone withdrawal in lipopolysaccharide-induced early pregnancy loss model. (Argentina) (full – 2016) https://academic.oup.com/molehr/article/22/11/800/2418643
Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring. (Spain) (full – 2016) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165432
Conceptus development and transcriptome at preimplantation stages in lactating dairy cows of distinct genetic groups and estrous cyclic statuses. (USA) (full – 2016) https://www.journalofdairyscience.org/article/S0022-0302(16)30095-9/fulltext
Dynamic of expression and localization of cannabinoid-degrading enzymes FAAH and MGLL in relation to CB1 during meiotic maturation of human oocytes. (Spain) (abst – 2016) https://link.springer.com/article/10.1007%2Fs00441-016-2381-2
The endocannabinoid system: an emergent player in human placentation. (Portugal) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0890623816300260
Endocannabinoids participate in placental apoptosis induced by hypoxia inducible factor- 1. (Argentina) (abst – 2016) https://link.springer.com/article/10.1007%2Fs10495-016-1274-x
Peripheral Blood Mononuclear Cells Infiltration Downregulates Decidual FAAH Activity in an LPS-Induced Embryo Resorption Model. (Argentina) (abst – 2016) https://www.ncbi.nlm.nih.gov/pubmed/27731508
Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity. (USA) (abst – 2016) https://www.sciencedirect.com/science/article/abs/pii/S0306987716302808
Formation of OX-1R/CB1R heteromeric complexes in embryonic mouse hypothalamic cells: Effect on intracellular calcium, 2-arachidonoyl-glycerol biosynthesis and ERK phosphorylation. (Italy/ Germany) (abst – 2016) https://www.sciencedirect.com/science/article/abs/pii/S1043661816306612
https://www.semanticscholar.org/paper/Formation-of-OX-1R%2FCB1R-heteromeric-complexes-in-on-Imperatore-Palomba/6c044ea082e256d19f1ba41a05da782e01fc0a3a Alcohol, Methamphetamine, and Marijuana Exposure Have Distinct Effects on the Human Placenta. (USA/ South Africa) (abst – 2016) https://www.semanticscholar.org/paper/Alcohol%2C-Methamphetamine%2C-and-Marijuana-Exposure-on-Carter-Wainwright/5fdb07b6c41640800886dc7dd1667357ff9a8d79
Immunohistochemistry Detected and Localized Cannabinoid Receptor Type 2 in Bovine Fetal Pancreas at Late Gestation. (Italy) (full – 2017) http://www.ejh.it/index.php/ejh/article/view/2761/2667
A Putative ‘Pre-Nervous’ Endocannabinoid System in Early Echinoderm Development. (USA/ Russia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866581/
Activation of Both CB1 and CB2 Endocannabinoid Receptors Is Critical for Masculinization of the Developing Medial Amygdala and Juvenile Social Play Behavior. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5272923/
Overactive type 2 cannabinoid receptor induces meiosis in fetal gonads and impairs ovarian reserve. (Italy) (full – 2017) http://www.nature.com/cddis/journal/v8/n10/full/cddis2017496a.html?foxtrotcallback=true
The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility. (UK) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501828/
The Roles of Anandamide, Fatty Acid Amide Hydrolase, and Leukemia Inhibitory Factor on the Endometrium during the Implantation Window. (China) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650704/
Suppression of STAT3 Signaling by Δ9-Tetrahydrocannabinol (THC) Induces Trophoblast Dysfunction. (China) (full – 2017) https://www.karger.com/Article/FullText/477603
Evidence for CB2 receptor involvement in LPS-induced reduction of cAMP intracellular levels in uterine explants from pregnant mice: pathophysiological implications. (Argentina) (full – 2017) https://academic.oup.com/molehr/article/23/7/500/3778489
Role of the endocannabinoid system in vertebrates: Emphasis on the zebrafish model. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636690/
Maternal alcohol exposure during mid-pregnancy dilates fetal cerebral arteries via endocannabinoid receptors. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517095/
Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4. (Australia/ France) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706968/
Adolescent Female Cannabinoid Exposure Diminishes the Reward-Facilitating Effects of Δ9-Tetrahydrocannabinol and d-Amphetamine in the Adult Male Offspring. (Greece/ USA) (full – 2017) http://journal.frontiersin.org/article/10.3389/fphar.2017.00225/full
THC Treatment Alters Glutamate Receptor Gene Expression in Human Stem Cell- Derived Neurons. (USA) (full – 2017) https://www.karger.com/Article/FullText/477762
Cannabis Use during Pregnancy: Pharmacokinetics and Effects on Child Development. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211194/
Metformin attenuates susceptibility to inflammation-induced preterm birth in mice with higher endocannabinoid levels. (USA) (full – 2017) https://academic.oup.com/biolreprod/advance-article-abstract/doi/10.1093/biolre/iox164/4693831?redirectedFrom=fulltext
Developmental effects of cannabidiol and Δ9-tetrahydrocannabinol in zebrafish. (USA) (full – 2017) https://academic.oup.com/toxsci/article/162/1/137/4585009
EFFECT OF MATERNAL HIGH-FAT DIET ON KEY COMPONENTS OF THE PLACENTAL AND HEPATIC ENDOCANNABINOID SYSTEM. (USA) (full – 2017) https://www.physiology.org/doi/full/10.1152/ajpendo.00119.2017
HDAC1 and HDAC3 Underlie Dynamic H3K9 Acetylation During Embryonic Neurogenesis and in Schizophrenia-like Animals. (Czech Republic/ Netherlands/ Austria/ Israel/ Italy) (link to PDF – 2017) https://www.researchgate.net/publication/315189959_HDAC1_and_HDAC3_Underlie_Dynamic_H3K9_Acetylation_During_Embryonic_Neurogenesis_and_in_Schizophrenia-like_Animals
CB1 cannabinoid receptor drives oocyte maturation and embryo development via PI3K/Akt and MAPK pathways. (Spain/ Columbia) (link to PDF – 2017) https://www.researchgate.net/publication/316316402_CB_1_cannabinoid_receptor_drives_oocyte_maturation_and_embryo_development_via_PI3KAkt_and_MAPK_pathways
The endocannabinoid system expression in the female reproductive tract is modulated by estrogen (Portugal) (link to PDF – 2017) https://www.researchgate.net/publication/318646677_The_endocannabinoid_system_expression_in_the_female_reproductive_tract_is_modulated_by_estrogen
What effects—if any—does marijuana use during pregnancy have on the fetus or child? (USA) (click “umsystemedu” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22What+effects%E2%80%94if+any%E2%80%94does+marijuana+use+during+pregnancy+have+on+the+fetus+or+child%3F+%22&btnG
Maternal Cannabinoid Use Alters Cannabinoid (CB1) and Endothelin (ETB) Receptor Expression in the Brains of Dams but Not Their Offspring. (USA) (abst – 2017) https://www.semanticscholar.org/paper/Maternal-Cannabinoid-Use-Alters-Cannabinoid-(CB1)-Amlani-Hornick/de0e18ec0ef5ef6908efc71413ce0074ee5e5afc
Interpretation of cannabis findings in the hair of very young children: mission impossible. (France) (abst – 2017) http://www.eurekaselect.com/157855/article
The synthetic cannabinoid WIN-55,212-55,212 induced-apoptosis in cytotrophoblasts cells by a mechanism dependent on CB1 receptor. (Portugal) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0300483X17301294?via%3Dihub
Neuro-glial cannabinoid receptors modulate signaling in the embryonic avian retina. (Brazil) (full – 2018) http://www.sciencedirect.com/science/article/pii/S0197018617302280
Cannabinoid Receptor Type 1 Expression in the Developing Avian Retina: Morphological and Functional Correlation With the Dopaminergic System. (Brazil) (full – 2018) https://www.frontiersin.org/articles/10.3389/fncel.2018.00058/full
Motor neuron development in zebrafish is altered by brief (5-hr) exposures to THC (∆9- tetrahydrocannabinol) or CBD (cannabidiol) during gastrulation. (Canada) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043604/
Marijuana Use During Pregnancy and Breastfeeding: Implications for Neonatal and Childhood Outcomes. (USA) (full – 2018) http://pediatrics.aappublications.org/content/142/3/e20181889.long
Sex Difference: What does cannabis do to the brain before birth? (Switzerland) (full – 2018) https://elifesciences.org/articles/41229
A cannabinoid receptor type 1 (CB1R) agonist enhance the developmental neurotoxicity of acetaminophen (paracetamol). (Sweden) (full – 2018) https://academic.oup.com/toxsci/article/166/1/203/5079325
Transcriptomic Characterization of the Human Habenula Highlights Drug Metabolism and the Neuroimmune System. (Canada/ USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220030/
Sex-dependent effects of in utero cannabinoid exposure on cortical function. (France/ USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162091/
Altered brain cannabinoid 1 receptor mRNA expression across postnatal development in the MAM model of schizophrenia. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203675/
Sex specific autistic endophenotypes induced by prenatal exposure to valproic acid involve anandamide signaling. (Italy) (full – 2018) https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14435
Additive drug-specific and sex-specific risks associated with co-use of marijuana and tobacco during pregnancy: Evidence from 3 recent developmental cohorts (2003-2015). (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116514/
Psychological Functioning of Women Taking Illicit Drugs during Pregnancy and the Growth and Development of Their Offspring in Early Childhood. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202263/
Prenatal tobacco and marijuana co-use: Impact on newborn neurobehavior. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239899/
An epidemiological, developmental and clinical overview of cannabis use during pregnancy. (Netherlands/ Norway/ USA) (full – 2018) https://www.sciencedirect.com/science/article/pii/S0091743518302676
Drug Use during Pregnancy and its Consequences: A Nested Case Control Study on Severe Maternal Morbidity. (Brazil) (full in English, abst in Portuguese – 2018) https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0038-1667291
Maternal and paternal cannabis use during pregnancy and the risk of psychotic-like experiences in the offspring. (Netherlands/ USA) (link to PDF – 2018) https://www.researchgate.net/publication/326224957_Maternal_and_paternal_cannabis_use_during_pregnancy_and_the_risk_of_psychotic-like_experiences_in_the_offspring Marijuana use during and after pregnancy and association of prenatal use on birth outcomes: A population-based study. (USA) (link to PDF – 2018) https://www.researchgate.net/publication/324093683_Marijuana_use_during_and_after_pregnancy_and_association_of_prenatal_use_on_birth_outcomes_A_population-based_study
Endocannabinoid Signaling in Embryonic Neuronal Motility and Cell–Cell Contact – Role of mGluR5 and TRPC3 Channels. (Finland) (click “helsinkifi” for download – 2018) https://scholar.google.com/scholar?q=Endocannabinoid+Signaling+in+Embryonic+Neuronal+Motility+and+Cell%E2%80%93Cell+Contact+%E2%80%93+%09Role+of+mGluR5+and+TRPC3+Channels.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Analysis of the Uptake, Metabolism, and Behavioral Effects of Cannabinoids on Zebrafish Larvae. (Canada) (click “Open Access”, then “nrcpublicationscanadaca” for download–2018) https://www.semanticscholar.org/paper/Analysis-of-the-Uptake%2C-Metabolism%2C-and-Behavioral-Achenbach-Hill/4d489bfc7ed79dc396c72416760a6d5064c6e125
A Modern Conundrum for the Pediatrician: The Safety of Breast Milk and the Cannabis- Using Mother. (USA) (article – 2018) http://pediatrics.aappublications.org/content/142/3/e20181921.long
Evaluation of Bisphenol A influence on endocannabinoid system in pregnant women. (Poland) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0045653518306234
CatSper: A Unique Calcium Channel of the Sperm Flagellum. (USA) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S2468867318300221
Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin. (USA) (abst – 2018) https://www.nature.com/articles/s41401-018-0073-z
https://www.semanticscholar.org/paper/Developmental-and-behavioral-effects-in-neonatal-of-Perchuk-Bierbower/1c51c30dea30cd1fefa6bf2701d83f80fe594c11
Effect of chronic THC administration in the reproductive organs of male mice, spermatozoa and in vitro fertilization. (Spain/ Columbia ) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303150
https://www.semanticscholar.org/paper/Effect-of-chronic-THC-administration-in-the-organs-L%C3%B3pez-Cardona-Ibarra-Lecue/64480904df7b4d10424f14c9b74abd360c02ab2c
Effects of feeding a source of omega-3 fatty acid during the early postpartum period on the endocannabinoid system in the bovine endometrium. (Iran) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0093691X18305880?via%3Dihub
Cannabidiol did not induce teratogenicity or neurotoxicity in exposed zebrafish embryos. (Brazil) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0009279718302163
Gestational Age-Dependent Interplay between Endocannabinoid Receptors and Alcohol in Fetal Cerebral Arteries. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497414/
Tetrahydrocannabinol Modulates in Vitro Maturation of Oocytes and Improves the Blastocyst Rates after in Vitro Fertilization. (Spain/ Colombia) (full – 2019) https://www.cellphysiolbiochem.com/Articles/000149/
Ontogeny and programming of the fetal temporal cortical endocannabinoid system by moderate maternal nutrient reduction in baboons (Papio spp.). (USA) (full – 2019) https://physoc.onlinelibrary.wiley.com/doi/full/10.14814/phy2.14024
Developmental and reproductive toxicity studies of BIA 10-2474. (USA/ Switzerland) (full–2019) https://www.sciencedirect.com/science/article/pii/S0273230019303071?via%3Dihub
Life-long epigenetic programming of cortical architecture by maternal ‘Western’ diet during pregnancy. (Austria/ UK/ Germany/France/ Italy/ Hungary/ Japan/ Canada/ USA/ Sweden) (link to PDF– 2019) https://www.researchgate.net/publication/337326915_Life-
long_epigenetic_programming_of_cortical_architecture_by_maternal_’Western’_diet_during_pregnancy
Adverse outcome pathway of developmental neurotoxicity resulting from prenatal exposures to cannabis contaminated with organophosphate pesticide residues. (USA) (link to PDF – 2019) https://www.researchgate.net/publication/330504784_Adverse_outcome_pathway_of_developmental_neurotoxicity_resulting_from_prenatal_exposures_to_cannabis_contaminated_with_organophosphate_pesticide_residues
Docosahexaenoic acid,22:6n-3: its roles in the structure and function of the brain. (India/ Finland/ Norway) (link to PDF – 2019) https://www.researchgate.net/publication/336635472_Docosahexaenoic_acid226n-
3_Its_roles_in_the_structure_and_function_of_the_brain
Marijuana Use in Pregnancy: An Updated Look at Marijuana Use and Its Impact on Pregnancy. (USA) (click “uswracir” for download – 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Marijuana+Use+in+Pregnancy%3A+An+Updated+Look+at+Marijuana+Use+and+Its+Impact+on+Pregnancy.&btnG
Multigenerational consequences of early-life cannabinoid exposure in zebrafish. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0041008X18305805
https://www.semanticscholar.org/paper/Multigenerational-consequences-of-early%E2%80%90life-in-Carty-Miller/93b2955e0a81c9f6ff7d8c9ae2d9772216018e12 Ethanol and cannabinoids interact to alter behavior in a zebrafish fetal alcohol spectrum disorder model. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30648819
Assessing the acute effects of prenatal synthetic cannabinoid exposure on murine fetal brain vasculature using optical coherence tomography. (USA) (abst – 2019) https://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201900050
Herring roe oil supplementation alters microglial cell gene expression and reduces peripheral inflammation after immune activation in a neonatal piglet model (USA) (abst–2019) https://www.sciencedirect.com/science/article/pii/S0889159119301606?via%3Dihub
Maternal high-fat diet impairs leptin signaling and up-regulates type-1 cannabinoid receptor with sex-specific epigenetic changes in the hypothalamus of newborn rats. (Brazil/ USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0306453018308412?via%3Dihub
Mice Missing Cnr1 and Cnr2 Show Implantation Defects. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30776303
Synthetic cannabinoids and their impact on neurodevelopmental processes. (Portugal) (abst – 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/adb.12824
Health care experiences and birth outcomes: Results of an Aboriginal birth cohort. (Australia) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S1871519219301337
The effect of high maternal linoleic acid on endocannabinoid signalling in rodent hearts. (Australia) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31814560
Early Exposure to THC Alters M-Cell Development in Zebrafish Embryos. (Canada) (full – 2020) https://www.mdpi.com/2227-9059/8/1/5/htm
Recreational Cannabis Legalization in the US and Maternal Use during the Preconception, Prenatal, and Postpartum Periods. (USA) (full – 2020) https://www.mdpi.com/1660-4601/17/3/909/htm
Focus on the endocannabinoid system and the reprotoxicity of marijuana in female users. (France) (abst in French & English – 2020) https://www.sciencedirect.com/science/article/pii/S2468718920300441


ENCEPHALITIS+
Anti-N-methyl-D-aspartate receptor encephalitis and drug abuse – the probable role of molecular mimicry or the overstimulation of CB receptors in a 17-year-old adolescent – case report. (Hungary) (download – 2016) http://epa.oszk.hu/02400/02454/00063/pdf/EPA02454_neuropsychopharmacologia_hungarica_2016_03_162-164.pdf


ENCEPHALOMYELITIS/EAE*+
Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells. (Israel/ USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363052/
A new formulation of cannabidiol in cream shows therapeutic effects in a mouse model of experimental autoimmune encephalomyelitis. (Italy) (full – 2015) https://link.springer.com/article/10.1186/s40199-015-0131-8
Activation of Cannabinoid CB2 receptors Reduces Hyperalgesia in an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464808/
Purified Cannabidiol, the main non-psychotropic component of Cannabis sativa, alone, counteracts neuronal apoptosis in experimental multiple sclerosis. (Italy) (link to PDF – 2015) http://www.europeanreview.org/article/10049
Neuroprotection in Experimental Autoimmune Encephalomyelitis and Progressive Multiple Sclerosis by Cannabis-Based Cannabinoids. (UK) (link to PDF – 2015) https://www.researchgate.net/publication/270004494_Neuroprotection_in_Experimental_Autoimmune_Encephalomyelitis_and_Progr essive_Multiple_Sclerosis_by_Cannabis-Based_Cannabinoids
HU-446 and HU-465, derivatives of the non-psychoactive cannabinoid cannabidiol, decrease the activation of encephalitogenic T cells. (Israel/ India) (link to download–2015) http://www.academia.edu/21241976/HU-446_and_HU-465_derivatives_of_the_non-
psychoactive_cannabinoid_cannabidiol_decrease_the_activation_of_encephalitogenic_T_cells
Interaction between the protective effects of cannabidiol and palmitoylethanolamide in experimental model of multiple sclerosis in C57BL/6 mice. (Iran) (click “READ THE FULL ARTICLE” for download–2015) https://realmofcaring.org/research/interaction-between-the-protective-effects-of-cannabidiol-and-palmitoylethanolamide-in-experimental-model-of-multiple-sclerosis-in-c57bl6-mice/
Activation of CB2 receptor is required for the therapeutic effect of ABHD6 inhibition in experimental autoimmune encephalomyelitis. (USA) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0028390815300162
Neuroprotective Effect Is Driven Through the Upregulation of CB1 Receptor in Experimental Autoimmune Encephalomyelitis. (China) (abst – 2015) https://link.springer.com/article/10.1007%2Fs12031-015-0656-9
https://www.semanticscholar.org/paper/Neuroprotective-Effect-Is-Driven-Through-the-of-CB1-Lou-Yu/4ade9fc49291692f1fe0207a4f53920765b91f12
The disease-modifying effects of a Sativex-like combination of phytocannabinoids in mice with experimental autoimmune encephalomyelitis are preferentially due to Δ(9)- tetrahydrocannabinol acting through CB1 receptors. (Spain) (abst – 2015) http://www.msard-journal.com/article/S2211-0348(15)00118-2/fulltext
Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. (Israel/ USA) (full – 2016) http://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0603-x
Interaction between interleukin-1β and type-1 cannabinoid receptor is involved in anxiety-like behavior in experimental autoimmune encephalomyelitis. (Italy/ Germany) (full – 2016) http://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0682-8
Development and Pharmacological Characterization of Selective Blockers of 2- Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. (Italy/ France/ USA) (full – 2016) https://escholarship.org/uc/item/0nc4z28r
Target regulation of PI3K/Akt/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis. (Italy) (click “orvosikannabiszcom” for download – 20 16) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Target+regulation+of+PI3K%2FAkt%2FmTOR+pathway+by+cannabidiol+in+treatment+of+experimental+multiple+sclerosis&btnG
WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism. (USA) (full – 2017) https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0783-4
Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid. (Israel) (full – 2017) http://www.mdpi.com/1422-0067/18/8/1669/htm

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(-)-β-Caryophyllene, a CB2 Receptor-Selective Phytocannabinoid, Suppresses Motor Paralysis and Neuroinflammation in a Murine Model of Multiple Sclerosis. (Brazil) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412277/
The endocannabinoid system and its therapeutic exploitation in multiple sclerosis: Clues for other neuroinflammatory diseases . (Italy) (full – 2017) http://www.sciencedirect.com/science/article/pii/S0301008217300709?via%3Dihub
Chapter 4 Neuropathic Pain in Multiple Sclerosis—Current Therapeutic Intervention and Future Treatment Perspectives. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/books/NBK470151/
Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis. (China/ Australia) (click “uswracir” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Amidoalkylindoles+as+Potent+and+Selective+Cannabinoid+Type+2+Receptor+Agonists+with+%09in+Vivo+Efficacy+in+a+Mouse+Model+of+Multiple+Sclerosis.%09%22&btnG
Sativex® effects on promoter methylation and on CNR1/CNR2 expression in peripheral blood mononuclear cells of progressive multiple sclerosis patients (Italy) (abst – 2017) https://www.sciencedirect.com/science/article/abs/pii/S0022510X17303921
Interferon-γ causes mood abnormalities by altering cannabinoid CB1 receptor function in the mouse striatum. (Italy) (abst – 2017) https://www.sciencedirect.com/science/article/pii/S0969996117301717?via%3Dihub
Mechanisms of action of cannabidiol in adoptively transferred experimental autoimmune encephalomyelitis. (Spain) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0014488617302212
Managing neuropathic pain in multiple sclerosis: Pharmacological interventions. (Australia) (abst – 2017) http://www.eurekaselect.com/155364/article
Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy. (Spain/ USA/ Italy/ Germany) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831753/
Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. (USA) (full – 2018) https://www.frontiersin.org/articles/10.3389/fimmu.2018.01782/full
The inhibition of CB1 receptor accelerates the onset and development of EAE possibly by regulating microglia/macrophages polarization. (China) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0165572817304678
Evaluation of Marijuana Compounds on Neuroimmune Endpoints in Experimental Autoimmune Encephalomyelitis. (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29512125
Avidekel Cannabis extracts and cannabidiol are as efficient as Copaxone in suppressing EAE in SJL/J mice. (Israel) (abst – 2018) https://link.springer.com/article/10.1007/s10787-018-0536-3
https://www.semanticscholar.org/paper/Avidekel-Cannabis-extracts-and-cannabidiol-are-as-Gallily-Yekhtin/00423dd73938053f6ccd2e3ec6cd4b2591fc5ff1
Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0889159119306476?via%3Dihub
Combination of Imipramine, a sphingomyelinase inhibitor, and β-caryophyllene improve their therapeutic effects on experimental autoimmune encephalomyelitis (EAE). (Iran) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31711937 


ENDOMETRIOSIS/ENDOMETRIUM+
Current Therapeutic Cannabis Controversies and Clinical Trial Design Issues. (USA) (full – 2016) http://journal.frontiersin.org/article/10.3389/fphar.2016.00309/full
The cannabinoid receptor CB1 contributes to the development of ectopic lesions in a mouse model of endometriosis. (Italy/ Spain) (full – 2016) https://academic.oup.com/humrep/article/32/1/175/2448170
Elevated Systemic Levels of Endocannabinoids and Related Mediators Across the Menstrual Cycle in Women With Endometriosis. (Italy) (click “PDF Reader” for full–2016) https://docksci.com/elevated-systemic-levels-of-endocannabinoids-and-related-mediators-across-the-me_5a1d94ccd64ab2efb50e484e.html
Cannabinoid receptor 1 contributes to sprouted innervation in endometrial ectopic growth through mitogen-activated protein kinase activation. (China) (click “PDF Reader” for full – 2016) https://docksci.com/elevated-systemic-levels-of-endocannabinoids-and-related-mediators-across-the-me_5a1d94ccd64ab2efb50e484e.html
Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release. (Portugal) (abst – 2016) https://www.semanticscholar.org/paper/Anandamide-interferes-with-human-endometrial-cell-Almada-Cunha/897b490f00a1b8be00b4e25759f54e0057401163
The Clinical Significance of Endocannabinoids in Endometriosis Pain Management (Israel) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436335/
Endocannabinoids modulate apoptosis in endometriosis and adenomyosis (Turkey) (link to PDF–2017) https://www.researchgate.net/publication/317146512_Endocannabinoids_modulate_apoptosis_in_endometriosis_and_adenomyosis
From pathogenesis to clinical practice: Emerging medical treatments for endometriosis (Italy) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S1521693418300397
Endocannabinoids as endometrial inflammatory markers in lactating Holstein cows. (Iran/ Italy) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29542183
Self-management strategies amongst Australian women with endometriosis: a national online survey. (Australia) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332532/
Decreased Expression of Cannabinoid Receptors in the Eutopic and Ectopic Endometrium of Patients with Adenomyosis. (China) (full – 2019) https://www.hindawi.com/journals/bmri/2019/5468954/
Selective Action of N-Arachidonoyl Dopamine on Viability and Proliferation of Stromal Cells from Eutopic and Ectopic Endometrium. (abst – 2019) https://link.springer.com/article/10.1007%2Fs10517-019-04456-6
Synthetic cannabinoids and endometrial stromal cell fate: Dissimilar effects of JWH-122, UR-144 and WIN55,212-2. (Portugal) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0300483X18303834?via%3Dihub
Anandamide targets aromatase: A breakthrough on human decidualization. (Portugal) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S1388198119301520
Self-Reported Efficacy of Cannabis for Endometriosis Pain. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S1553465019310921
Cannabis Use, a Self-Management Strategy Among Australian Women With Endometriosis: Results From a National Online Survey. (Australia) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31722852
The role of the endocannabinoid system in aetiopathogenesis of endometriosis: A potential therapeutic target. (Australia/ Switzerland) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31785471
Disease-modifying effects of natural Δ9-tetrahydrocannabinol in endometriosis- associated pain. (Spain) (full– 2020) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977967/


ENDOTOXEMIA
Metabolic endotoxemia affects about 33% of Americans Cannabinoid Receptor 2 Modulates Neutrophil Recruitment in a Murine Model of Endotoxemia. (UK) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567445/
Low-fat yogurt consumption reduces biomarkers of chronic inflammation and inhibits markers of endotoxin exposure in healthy premenopausal women: a randomised controlled trial. (USA) (full in English & French – 2017) https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/lowfat-yogurt-consumption-reduces-biomarkers-of- chronic-inflammation-and-inhibits-markers-of-endotoxin-exposure-in-healthy-premenopausal-women-a-randomised-controlled- trial/B7ED318F1F80DCC04DBC348700C071C1/core-reader
TLR4 Receptor Induces 2-AG–Dependent Tolerance to Lipopolysaccharide and Trafficking of CB2 Receptor in Mast Cells. (Mexico/ France) (abst – 2019) https://www.jimmunol.org/content/202/8/2360.long


ENERGY DRINKS
Consuming energy drinks at the age of 14 predicted legal and illegal substance use at 16 (Switzerland) (abst–2016) https://www.semanticscholar.org/paper/Consuming-energy-drinks-at-the-age-of-14-predicted-Barrense-Dias-Berchtold/ac39cf2852cbde50a03752101bc681844b77d051
The role of energy drink consumption in the intention to initiate marijuana use among adolescents. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0306460319301285?via%3Dihub


EPIDERMOLYSIS BULLOSA*+
Self-initiated use of topical cannabidiol oil for epidermolysis bullosa. (USA) (full – 2018) beyondthc.com Dermatology-Related Uses of Medical Cannabis Promoted by Dispensaries in Canada, Europe, and the United States. (Canada) (abst – 2018) http://journals.sagepub.com/doi/abs/10.1177/1203475418808761?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=cmsa
Combined tetrahydrocannabinol and cannabidiol to treat pain in epidermolysis bullosa: a report of three cases. (Netherlands) (full – 2019) https://onlinelibrary.wiley.com/doi/full/10.1111/bjd.17341


EPILEPSY/SEIZURES*+
Augmented Inhibition from Cannabinoid-Sensitive Interneurons Diminishes CA1 Output after Traumatic Brain Injury. (USA) (full – 2015) http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00435/full
Muscarinic M1 receptor and cannabinoid CB1 receptor do not modulate paraoxon- induced seizures. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317231/
Medicinal cannabis. (Australia) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674028/

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Cannabidiol Rescues Acute Hepatic Toxicity and Seizure Induced by Cocaine. (Brazil) (full – 2015) http://www.hindawi.com/journals/mi/2015/523418/
Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms. (Canada/ USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423390/
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284516/
Interaction between Cannabinoid Compounds and Capsazepine in Protection against Acute Pentylenetetrazole-induced Seizure in Mice. (Iran) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499434/
Phytocannabinoids and epilepsy. (Brazil) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1111/jcpt.12235/full
Cannabinoids and Epilepsy. (Brazil) (full – 2015) http://link.springer.com/article/10.1007%2Fs13311-015-0375-5
Impaired 2-AG signaling in hippocampal glutamatergic neurons: aggravation of anxiety- like behavior and unaltered seizure susceptibility. (Germany/ Australia) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772822/
Cannabinoids: is there a potential treatment role in epilepsy? (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845642/
Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks. (Italy) (full – 2015) http://cercor.oxfordjournals.org/content/early/2015/11/17/cercor.bhv274.long
TRPV1 Channel: A Potential Drug Target for Treating Epilepsy. (Turkey) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598436/
Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders. (USA) (full – 2015) http://ascpjournal.biomedcentral.com/articles/10.1186/s13722-015-0032-7
Homer Protein-Metabotropic Glutamate Receptor Binding Regulates Endocannabinoid Signaling and Affects Hyperexcitability in a Mouse Model of Fragile X Syndrome. (USA) (full – 2015) http://www.jneurosci.org/content/35/9/3938.long
Enhancement of endocannabinoid signalling protects against cocaine-induced neurotoxicity. (Brazil) (full – 2015) http://www.sciencedirect.com/science/article/pii/S0041008X15001556
Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy. (USA) (full – 2015) http://onlinelibrary.wiley.com/doi/10.1111/epi.13060/full
Marijuana: A Time-Honored but Untested Treatment for Epilepsy. (Canada) (full – 2015) https://www.cambridge.org/core/journals/canadian-journal-of-neurological-sciences/article/div-classtitlemarijuana-a- time-honored-but-untested-treatment-for-epilepsydiv/DDEDDD9EAA09918D3D69CC7CA047AE5C/core-reader

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Molecular Targets of Cannabidiol in Neurological Disorders. (UK) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604182/
A New Differential Diagnosis: Synthetic Cannabinoids-Associated Acute Renal Failure. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666428/
Marijuana Legalization: Impact on Physicians and Public Health. (USA) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900958/
The basolateral amygdala γ-aminobutyric acidergic system in health and disease. (USA) (full – 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837071/
Cannabinoid and nitric oxide signaling interplay in the modulation of hippocampal hyperexcitability: Study on electrophysiological and behavioral models of temporal lobe epilepsy in the rat. (Italy) (full – 2015) https://www.academia.edu/17120812/Cannabinoid_and_nitric_oxide_signaling_interplay_in_the_modulation_of_hippocampal_hyperexcitability_Study_on_electrophysiological_and_behavioral_models_of_temporal_lobe_epilepsy_in_the_rat
ACEA (a highly selective cannabinoid CB1 receptor agonist) stimulates hippocampal neurogenesis in mice treated with antiepileptic drugs. (Poland) (full – 2015) https://www.academia.edu/23685614/ACEA_a_highly_selective_cannabinoid_CB1_receptor_agonist_stimulates_hippocampal_neurogenesis_in_mice_treated_with_antiepileptic_drugs
The effects of adolescent cannabinoid exposure on seizure susceptibility and lethality in adult male rats. (USA) (full – 2015) https://www.academia.edu/20941362/The_effects_of_adolescent_cannabinoid_exposure_on_seizure_susceptibility_and_lethality_in_adult_male_rats
Options for pharmacoresistant epilepsy in children: when medications don’t work. (USA) (link to PDF – 2015) https://www.researchgate.net/publication/272077097_Options_for_Pharmacoresistant_Epilepsy_in_Children_When_Medications_Don%27t_Work
Marijuana Use in Epilepsy: The Myth and the Reality. (USA) (link to PDF – 2015) https://www.researchgate.net/publication/281486167_Marijuana_Use_in_Epilepsy_The_Myth_and_the_Reality
Cannabidiol as potential treatment in refractory pediatric epilepsy. (Italy) (link to PDF–2015) https://www.researchgate.net/publication/283903203_Cannabidiol_as_potential_treatment_in_refractory_pediatric_epilepsy
The role of cannabinoids and leptin in neurological diseases. (Turkey) (link to PDF–2015) https://www.researchgate.net/publication/287360490_The_role_of_cannabinoids_and_endocannabinoid_system_in_the_treatment_of_epilepsy
Weeding out bad waves: towards selective cannabinoid circuit control in epilepsy. (USA/ Japan) (link to PDF – 2015) https://www.researchgate.net/publication/275215978_Weeding_out_bad_waves_Towards_selective_cannabinoid_circuit_control_in_ epilepsy
Pure cannabidiol in the treatment of malignant migrating partial seizures in infancy: a case report. (USA) (download – 2015) http://www.orvosikannabisz.com/wp-content/uploads/2016/12/Pure-Cannabidiol-in-the-Treatment-of-Malignant-Migrating-Partial-Seizures-in-Infancy-A-Case-Report-Saade2015-2.pdf
Population Pharmacokinetic Model of THC Integrates Oral, Intravenous, and Pulmonary Dosing and Characterizes Short- and Long-term Pharmacokinetics. (Netherlands) (download – 2015) https://bps.conference-services.net/resources/344/3811/pdf/PHARM14_0032.pdf
An outbreak of acute delirium from exposure to the synthetic cannabinoid AB- CHMINACA. (USA) (link to download – 2015) https://www.academia.edu/19347966/An_outbreak_of_acute_delirium_from_exposure_to_the_synthetic_cannabinoid_AB-CHMINACA
Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial. (USA) (click “researchgate” for download– 2015) https://scholar.google.com/scholar?cluster=5587800066287982849&hl=en&as_sdt=0,5&as_vis=1&scioq=%22Cannabidiol+in+patients+with+treatment-resistant+epilepsy:+an+open-label+interventional+trial%22 Perceived efficacy of cannabidiol-enriched cannabis extracts for treatment of pediatric epilepsy: A potential role for infantile spasms and Lennox-Gastaut syndrome. (USA) (click “semanticscholar” for download – 2015) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Perceived+efficacy+of+cannabidiol-enriched+cannabis+extracts+for+treatment+of+pediatric+epilepsy%3A+A+potential+role+for+infantile+spasms+and+Lennox- Gastaut+syndrome.%22&btnG Palmitoylethanolamide attenuates PTZ-induced seizures through CB1 and CB2 receptors. (Iran) (click “gumsacir” for download – 2015) https://scholar.google.com/scholar?q=Palmitoylethanolamide+attenuates+PTZ-induced+seizures+through+CB1+and+CB2+receptors.&hl=en&as_sdt=0&as_vis=1&oi=scholart
Changes over time of cannabinoid receptor 1 in hippocampus of status epilepticus rats (China) (abst in English – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26168676
(abst in Chinese – 2015) http://zhyxzz.yiigle.com/CN112137201505/125169.htm?locale=zh_CN
Attenuation of kainic acid-induced status epilepticus by inhibition of endocannabinoid transport and degradation in guinea pigs. (Russia) (abst – 2015) https://www.sciencedirect.com/science/article/pii/S0920121115000133
https://www.semanticscholar.org/paper/Attenuation-of-kainic-acid-induced-status-by-of-and-Shubina-Aliev/22465235dc102e4b7ca99a4cae54ac72af4787ab
Neuroprotective effects of trans-caryophyllene against kainic Acid induced seizure activity and oxidative stress in mice. (China) (abst – 2015) https://www.semanticscholar.org/paper/Neuroprotective-Effects-of-Trans-Caryophyllene-Acid-Liu-Song/f8ce9bcb572371a7e107776e958023208adb187e
Effects of WIN 55,212-2 (a synthetic cannabinoid CB1 and CB2 receptor agonist) on the anticonvulsant activity of various novel antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice. (Poland) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0091305715000052
Issues and promise in clinical studies of botanicals with anticonvulsant potential. (Israel) (abst– 2015) https://eurekamag.com/research/004/446/004446031.php
A Common Source Outbreak of Severe Delirium Associated with Exposure to the Novel Synthetic Cannabinoid ADB-PINACA. (USA) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25726258
Inhibition of monoacylglycerol lipase mediates a cannabinoid 1-receptor dependent delay of kindling progression in mice. (Germany) (abst – 2015) https://www.sciencedirect.com/science/article/pii/S0969996115000881
Withdrawal Seizures Seen In the Setting of Synthetic Cannabinoid Abuse. (USA) (abst – 2015) http://www.ajemjournal.com/article/S0735-6757%2815%2900169-2/abstract

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Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy. (USA) (abst – 2015) http://www.epilepsybehavior.com/article/S1525-5050(15)00104-3/fulltext
Influence of arachidonyl-2′-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the anticonvulsant and acute side-effect potentials of clobazam, lacosamide and pregabalin in the maximal electroshock-induced seizure model and chimney test in mice. (Poland) (abst – 2015) https://www.semanticscholar.org/paper/Influence-of-arachidonyl-2%27-chloroethylamide%2C-a-CB1-Florek-Luszczki-
Zagaja/9afc69aba34a5995f8fc835b1b6a2808127c18f1 Long-term disease-modifying effect of the endocannabinoid agonist WIN55,212-2 in a rat model of audiogenic epilepsy. (Russia/ Netherlands) (abst – 2015) https://www.sciencedirect.com/science/article/abs/pii/S1734114014003739?via%3Dihub
JWH-018 impairs sensorimotor functions in mice. (Italy) (abst – 2015) https://www.sciencedirect.com/science/article/abs/pii/S0306452215004534
https://www.semanticscholar.org/paper/JWH-018-impairs-sensorimotor-functions-in-mice-Ossato-Vigolo/e56c80a5e45266db76e9d1a9e3f18ff7942e572e
Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release. (Brazil) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0161813X15001229
Cytochrome P450-mediated metabolism of the synthetic cannabinoids UR-144 and XLR- 11. (Denmark) (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/26360322
Cannabis and Endocannabinoid Signaling in Epilepsy. (Hungary) (abst – 2015) http://link.springer.com/chapter/10.1007%2F978-3-319-20825-1_10
Polypharmacology Shakes Hands with Complex Aetiopathology. (UK/ Italy) (abst – 2015) https://www.cell.com/trends/pharmacological-sciences/fulltext/S0165-6147(15)00171-6
Convulsant effects of high efficacy synthetic cannabinoid JWH-018 in mice. (USA) (abst – 2015) https://www.fasebj.org/doi/10.1096/fasebj.29.1_supplement.614.7
The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazole- induced seizure severity in Wistar rats. (Brazil/ USA) (abst – 2015) https://www.sciencedirect.com/science/article/pii/S0920121116301310
The Pharmacological Basis of Cannabis Therapy for Epilepsy. (USA) (full – 2016) http://jpet.aspetjournals.org/content/357/1/45.long
Cannabinoids for pediatric epilepsy? Up in smoke or real science? (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729003/
Transient increase of interleukin-1β after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling. (China/ Canada) (full – 2016) http://www.nature.com/articles/srep21931
Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome. (Spain/ Italy) (full – 2016) http://onlinelibrary.wiley.com/doi/10.1002/prp2.220/full
ABC transporters P-gp and Bcrp do not limit the brain uptake of the novel antipsychotic and anticonvulsant drug cannabidiol in mice. (Australia) (full – 2016) https://peerj.com/articles/2081/
CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience. (Israel) (full – 2016) http://www.seizure-journal.com/article/S1059
-1311(16)00005-4/fulltext Case Series of Synthetic Cannabinoid Intoxication from One Toxicology Center. (USA) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899060/
Fatty Acid Binding Proteins (FABPs) are Intracellular Carriers for Δ9- Tetrahydrocannabinol (THC) and Cannabidiol (CBD). (USA) (full – 2016) http://www.jbc.org/content/290/14/8711.full
Investigational new drugs for focal epilepsy. (UK) (full – 2016) http://www.tandfonline.com/doi/full/10.1517/13543784.2016.1110144
Is the medical use of cannabis a therapeutic option for children? (Canada) (full – 2016) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758425/
Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction. (Spain) (full – 2016) http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=10095&path%5B
%5D=31745 Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy. (USA/ China) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785070/
Crucial Roles of the Endocannabinoid 2-Arachidonoylglycerol in the Suppression of Epileptic Seizures. (Japan) (full – 2016) http://www.cell.com/cell-reports/fulltext/S2211-1247(16)30852-X
Turning Up the Heat on Endocannabinoid Signaling. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106110/
Δ9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Switching to Purified Cannabidiol. (Brazil/ Italy) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043219/
Medical Marijuana for Epilepsy? (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911937/
Investigational new drugs for focal epilepsy. (UK) (full – 2016) http://www.tandfonline.com/doi/full/10.1517/13543784.2016.1110144
Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958898/
Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy. (USA/ China) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785070/
Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures. (Brazil) (full – 2016) http://www.epilepsybehavior.com/article/S1525-5050(15)00695-2/fulltext
Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation. (UK) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135680/
From cannabis to cannabidiol to treat epilepsy, where are we? (Italy/ UK) (link to PDF– 2016) https://www.researchgate.net/publication/307592827_From_Cannabis_to_Cannabidiol_to_Treat_Epilepsy_Where_Are_We
Current Status and Prospects for Cannabidiol Preparations as New Therapeutic Agents. (USA) (download – 2016) https://www.semanticscholar.org/paper/Current-Status-and-Prospects-for-Cannabidiol-as-New-Fasinu-Phillips/f079326032ec0e932601466d7beb81bc191baa67
Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl- 2′-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. (Italy) (click “coreacuk” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Pharmacokinetic-pharmacodynamic+influence+of+N-palmitoylethanolamine%2C+arachidonyl-2%E2%80%B2-chloroethylamide+and+WIN+55%2C212-2+on+the+anticonvulsant+activity+of+antiepileptic+drugs+against+audiogenic+seizures+in+DBA%2F2+mice%22&btnG
Effects of Marijuana on ictal and interictal EEG activity in idiopathic generalized epilepsy. (USA) (click “semanticscholar” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Effects+of+Marijuana+on+ictal+and+interictal+EEG+activity+in+idiopathic+generalized+epilepsy.+++%22&btnG
Cannabidiol Post-Treatment Alleviates Rat Epileptic-Related Behaviors and Activates Hippocampal Cell Autophagy Pathway Along with Antioxidant Defense in Chronic Phase of Pilocarpine-Induced Seizure. (Iran) (click “therocus” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Cannabidiol+Post-Treatment+Alleviates+Rat+Epileptic-Related+Behaviors+and+Activates+Hippocampal+Cell+Autophagy+Pathway+Along+with+Antioxidant+Defense+in+Chronic+Phase +of+Pilocarpine-Induced+Seizure.+++++++%22&btnG
Cannabis and epilepsy: An ancient treatment returns to the fore. (USA) (click “orvosikannabiz” for download – 2016) https://www.researchgate.net/publication/311737721_Cannabis_and_epilepsy_An_ancient_treatment_returns_to_the_fore
Synthetic cannabinoids revealing adrenoleukodystrophy (Israel) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S0967586815004567
https://www.semanticscholar.org/paper/Synthetic-cannabinoids-revealing-Fellner-
Benninger/8f0f9681b328e42bf3b659a21865198f9b938cb9
Adverse effects after the use of JWH-210 – a case series from the EU Spice II plus project (Germany) (abst – 2016) https://www.semanticscholar.org/paper/Adverse-effects-after-the-use-of-JWH-210-a-case-the-Hermanns-Clausen-Kithinji/7f72a2b975a3b9ff5c94c83c951d24cd69574361
Plant-Derived and Endogenous Cannabinoids in Epilepsy. (Italy) (abst – 2016) https://link.springer.com/article/10.1007/s40261-016-0379-x
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. (Italy) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S0278584616300069
Involvement of TRPV1 channels in the activity of the cannabinoid WIN 55,212-2 in an acute rat model of temporal lobe epilepsy. (Italy) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S092012111630016X
Cannabidiol and epilepsy: rationale and therapeutic potential. (Italy) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S1043661816301797
LACTIC ACIDOSIS: A RARE MANIFESTATION OF SYNTHETIC MARIJUANA INTOXICATION (USA) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27159480
MEDICAL CANNABIS. (Israel) (abst – 2016) http://www.ncbi.nlm.nih.gov/pubmed/27215115
CB1 Receptor Antagonism Prevents Long-Term Hyperexcitability after Head Injury by of Dynorphin-KOR System and mGluR5 in Rat Hippocampus. (China) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S0006899316304243
The cannabinoid receptor agonist WIN55.212 reduces consequences of status epilepticus in rats. (Russia/ Netherlands) (abst – 2016) https://www.sciencedirect.com/science/article/abs/pii/S0306452216303670
Marijuana use in adults admitted to a Canadian epilepsy monitoring unit. (Canada) (abst – 2016) http://www.epilepsybehavior.com/article/S1525-5050(16)30334-1/fulltext
Endogenous cannabinoid system alterations and their role in epileptogenesis after brain injury in rat. (China) (abst – 2016) https://www.sciencedirect.com/science/article/pii/S0920121116302406?via%3Dihub
Targeting brain and peripheral plasticity of the lipidome in acute kainic acid-induced epileptic seizures in mice via quantitative mass spectrometry. (Germany) (abst – 2016) http://www.sciencedirect.com/science/article/pii/S1388198116303092
Synaptic Reorganization of the Perisomatic Inhibitory Network in Hippocampi of Temporal Lobe Epileptic Patients. (Hungary) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237728/
Endocannabinoids: A Promising Impact for Traumatic Brain Injury. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314139/
Protective Effects of Cannabidiol against Seizures and Neuronal Death in a Rat Model of Mesial Temporal Lobe Epilepsy. (Brazil) (full – 2017) http://journal.frontiersin.org/article/10.3389/fphar.2017.00131/full
A Long-Term Treatment with Arachidonyl-2′-Chloroethylamide Combined with Valproate Increases Neurogenesis in a Mouse Pilocarpine Model of Epilepsy. (USA) (full – 2017) https://www.mdpi.com/1422-0067/18/5/900/htm
Cannabinoids in Pediatrics. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473390/
Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy? (Republic of Korea) (full – 2017) http://www.j-epilepsy.org/journal/view.php?year=2017&vol=7&page=16
Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid. (Israel) (full – 2017) http://www.mdpi.com/1422-0067/18/8/1669/htm
An Australian nationwide survey on medicinal cannabis use for epilepsy: History of antiepileptic drug treatment predicts medicinal cannabis use (Australia) (full–2017) http://www.epilepsybehavior.com/article/S1525-5050(17)30073-2/fulltext
Effects of arachidonyl-2′-chloroethylamide (ACEA) on the protective action of various antiepileptic drugs in the 6-Hz corneal stimulation model in mice. (Poland) (full – 2017) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183873
An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. (Germany) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
Addressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons. (Germany) (full – 2017) https://link.springer.com/article/10.1007%2Fs00429-017-1411-5
The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity. (Italy/ Malta/ UK) (full – 2017) https://www.nature.com/articles/s41598-017-11606-1
Report from a Survey of Parents Regarding the Use of Cannabidiol (Medicinal cannabis) in Mexican Children with Refractory Epilepsy. (Mexico) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368357/
The Role of BK Channels in Antiseizure Action of the CB1 Receptor Agonist ACEA in Maximal Electroshock and Pentylenetetrazole Models of Seizure in Mice. (Iran) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603872/
Cannabinoid antagonist SLV326 induces convulsive seizures and changes in the interictal EEG in rats. (Netherlands/ Russia/ Germany) (full – 2017) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165363
A spicy status: Synthetic cannabinoid (spice) use and new-onset refractory status epilepticus—A case report and review of the literature. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721953/
Spice-y Kidney Failure: A Case Report and Systematic Review of Acute Kidney Injury Attributable to the Use of Synthetic Cannabis. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424589/
Rare genetic variants in the endocannabinoid system genes CNR1 and DAGLA are associated with neurological phenotypes in humans. (USA) (full – 2017) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187926
Do Cannabinoids Confer Neuroprotection Against Epilepsy? An Overview. (Italy) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738750/
Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last? (Italy) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767492/
Characteristics and Treatment of Patients with Clinical Illness Due to Synthetic Cannabinoid Inhalation Reported by Medical Toxicologists: A ToxIC Database Study. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440319/
Synthetic Pot: Not Your Grandfather’s Marijuana. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329767/
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome. (USA) (full – 2017) https://www.nejm.org/doi/10.1056/NEJMoa1611618?url_ver=Z39.88-
2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dwww.ncbi.nlm.nih.gov Synthetic cannabinoid “Black Mamba” infidelity in patients presenting for emergency stabilization in Colorado: a P SCAN Cohort. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786486/
Inhibition of monoacylglycerol lipase terminates diazepam-resistant status epilepticus in mice and its effects are potentiated by a ketogenic diet. (Italy/ USA) (full – 2017) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.13950
Anticonvulsant effect of cannabinoid receptor agonists in models of seizures in developing rats. (USA) (full – 2017) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.13842
Cannabinoids for epilepsy: What do we know and where do we go? (UK/ Sweden) (full – 2017) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.13973
Medical Cannabinoids in Children and Adolescents: A Systematic Review. (USA) (full – 2017) https://pediatrics.aappublications.org/content/140/5/e20171818.long
Fatty acid amide hydrolase inhibitor URB597 may protect against kainic acid-induced damage to hippocampal neurons: Dependence on the degree of injury. (Russia) (full – 2017) https://www.nature.com/articles/s41598-017-11606-1
Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. (USA/ Australia) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363769/
Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection. (UK/ USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651410/
Cannabinoid receptor 1/2 double-knockout mice develop epilepsy. (USA/ Brazil) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716894/
Chronic Inflammatory Pain Impairs mGluR5-Mediated Depolarization-Induced Suppression of Excitation in the Anterior Cingulate Cortex. (China) (full -2017) https://academic.oup.com/cercor/article/28/6/2118/3829385
Antiepileptic drugs in clinical development: differentiate or die? (Germany/ Italy) (link to PDF–2017) https://www.researchgate.net/publication/319086508_Antiepileptic_Drugs_in_Clinical_Development_Differentiate_or_Die
Inhibitor of Endocannabinoid Deactivation Protects Against In Vitro and In Vivo Neurotoxic Effects of Paraoxon. (USA/ South Africa) (link to PDF– 2017) https://www.researchgate.net/publication/319088396_Inhibitor_of_Endocannabinoid_Deactivation_Protects_Against_In_Vitro_and_In_Vivo_Neurotoxic_Effects_of_Paraoxon Cannabinoids in treatment-resistant epilepsy: A review. (Spain) (link to PDF–2017) https://www.researchgate.net/publication/313492542_Cannabinoids_in_treatment-resistant_epilepsy_A_review
The Direct Actions of Cannabidiol and 2-Arachidonoyl Glycerol at GABAA Receptors (Australia) (link to PDF–2017) https://www.researchgate.net/publication/314109989_The_Direct_Actions_of_Cannabidiol_and_2-Arachidonoyl_Glycerol_at_GABAA_Receptors
Endocannabinoid-dependent protection against kainic acid-induced long-term alteration of brain oscillations in guinea pigs. (Russia) (link to PDF – 2017) https://www.researchgate.net/publication/313573682_Endocannabinoid-dependent_protection_against_kainic_acid-induced_long-term_alteration_of_brain_oscillations_in_guinea_pigs
Anticonvulsant effect of cannabidiol in the pentylenetetrazole model: Pharmacological mechanisms, electroencephalographic profile, and brain cytokine levels. (Brazil) (click “unifalmgedubr” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Anticonvulsant+effect+of+cannabidiol+in+the+pentylenetetrazole+model%3A+Pharmacological+mechanisms%2C+electroencephalographic+profile%2C+and+brain+cytokine+levels&btnG
Neurological aspects of medical use of cannabidiol. (Italy) (click “coreacuk” for download – 2017) https://scholar.google.com/scholar?q=Neurological+Aspects+of+Medical+Use+of+Cannabidiol&hl=en&as_sdt=0&as_vis=1&oi=scholart
Human Toxicity Caused by Indole and Indazole Carboxylate Synthetic Cannabinoid Receptor Agonists: From Horizon Scanning to Notification. (UK) (click “aaccjnls” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Human+Toxicity+Caused+by+Indole+and+Indazole+Carboxylate+Synthetic+Cannabinoid+Receptor+Agonists%3A+From+Horizon+Scanning+to+Notification%22&btnG
Intoxication from the novel synthetic cannabinoids AB-PINACA and ADB-PINACA: A case series and review of the literature. (USA) (click “ucsfedu” for download – 2017) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Intoxication+from+the+novel+synthetic+cannabinoids+AB-PINACA+and+ADB-PINACA%3A+A+case+series+and+review+of+the+literature%22&btnG Neuronal nitric oxide synthase is involved in CB/TRPV1 signalling: Focus on control of hippocampal hyperexcitability. (Italy) (click “coreacuk” for download – 2017) https://scholar.google.com/scholar?q=Neuronal+nitric+oxide+synthase+is+involved+in+CB/TRPV1+signalling:+Focus+on+control+of+hippocampal+hyperexcitability&hl=en&as_sdt=0&as_vis=1&oi=scholart Interaction between urethane and cannabinoid CB1 receptor agonist and antagonist in penicillin-induced epileptiform activity. (Turkey) (click “Free Full PDF” for download – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28691717
New-Onset Refractory Status Epilepticus Associated With the Use of Synthetic st Cannabinoids. (USA) (1 page – 2017) http://www.psychosomaticsjournal.com/article/S0033-3182(16)30124-4/fulltext
Cannabis use in Epilepsy. Current situation in Argentina and abroad. (Argentina) (abst in English – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28898306
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Historical perspective on the medical use of cannabis for epilepsy: Ancient times to the 1980s. (USA) (abst – 2017) http://www.epilepsybehavior.com/article/S1525-5050(16)30666-7/fulltext
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Neuroimaging studies towards understanding the central effects of pharmacological cannabis products on patients with epilepsy. (USA) (abst – 2017) https://www.sciencedirect.com/science/article/abs/pii/S1525505016306229
Social factors in marijuana use for medical and recreational purposes. (USA) (abst – 2017) http://www.epilepsybehavior.com/article/S1525-5050(16)30618-7/fulltext
Pharmacology of cannabinoids in the treatment of epilepsy. (USA) (abst – 2017) https://www.epilepsybehavior.com/article/S1525-5050(16)30579-0/fulltext

Social correlates of health status, quality of life, and mood states in patients treated with cannabidiol for epilepsy. (USA) (abst – 2017) https://www.sciencedirect.com/science/article/abs/pii/S1525505016307314
Cannabinoids therapeutic use: what is our current understanding following the introduction of THC, THC:CBD oromucosal spray and others? (Italy/ Spain/ Germany) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28276775
Cannabinoids as hippocampal network administrators. (USA) (abst – 2017) https://www.sciencedirect.com/science/article/abs/pii/S0028390817301405
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Analytical confirmation of synthetic cannabinoids in a cohort of 179 presentations with acute recreational drug toxicity to an Emergency Department in London, UK in the first half of 2015. (UK/ Belgium) (abst – 2017) https://www.semanticscholar.org/paper/Analytical-confirmation-of-synthetic-cannabinoids-a-Abouchedid-
Hudson/43414db17daf86cd4644238f6de9e27ea06f3ffe Cannabidiol Treatment for Refractory Seizures in Sturge-Weber Syndrome. (USA) (abst – 2017) https://www.sciencedirect.com/science/article/abs/pii/S088789941730053X
Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP). (abst – 2017) https://link.springer.com/article/10.1007/s11064-017-2287-8
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Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems. (Italy) (abst – 2017) https://www.semanticscholar.org/paper/Altered-responses-of-dopamine-D3-receptor-null-mice-Micale-Cristino/e33564365e31533850f991a2fcd0dc95e54bb8b6 Disseminated aspergillosis in an HIV-positive cannabis user taking steroid treatment (UK) (abst – 2017) http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(17)30438-3/fulltext
The potential role of cannabinoids in epilepsy treatment. (Italy) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/28845714
Synthetic cannabinoid AM2201 induces seizures: Involvement of cannabinoid CB1 receptors and glutamatergic transmission. (Japan) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0041008X17304155
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Simple and fast gas-chromatography mass spectrometry assay to assess delta 9- tetrahydrocannabinol and cannabidiol in dogs treated with medical cannabis for canine epilepsy. (Italy) (abst – 2017) http://www.eurekaselect.com/157592/article
Efficacy and safety of cannabis for treating children with refractory epilepsy. (UK) (abst – 2017) https://www.ncbi.nlm.nih.gov/pubmed/29115760
Efficacy of artisanal preparations of cannabidiol for the treatment of epilepsy: Practical experiences in a tertiary medical center. (USA) (full – 2018) http://www.epilepsybehavior.com/article/S1525-5050(18)30009-X/fulltext
Cannabidiol Regulates Long Term Potentiation Following Status Epilepticus: Mediation by Calcium Stores and Serotonin. (Israel) (full – 2018) https://www.frontiersin.org/articles/10.3389/fnmol.2018.00032/full
Positron emission tomography imaging of cerebral glucose metabolism and type 1 cannabinoid receptor availability during temporal lobe epileptogenesis in the amygdala kindling model in rhesus monkeys. (Belgium) (full – 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.14059
Therapeutic potential of medicinal marijuana: an educational primer for health care professionals. (Canada) (full – 2018) https://www.dovepress.com/therapeutic-potential-of-medicinal-marijuana-an-educational-primer-for-peer-reviewed-fulltext-article-DHPS Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin. (Italy/ Netherlands) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719834/
Antiepileptogenic Effect of Subchronic Palmitoylethanolamide Treatment in a Mouse Model of Acute Epilepsy. (Germany) (full – 2018) https://www.frontiersin.org/articles/10.3389/fnmol.2018.00067/full
Pediatric Death Due to Myocarditis After Exposure to Cannabis. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965161/
Review of the neurological benefits of phytocannabinoids. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938896/
Notes from the Field: Acute Poisonings from a Synthetic Cannabinoid Sold as Cannabidiol — Utah, 2017–2018. (USA) (full – 2018) https://www.cdc.gov/mmwr/volumes/67/wr/mm6720a5.htm?s_cid=mm6720a5_w
Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community. (Australia) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033872/
Cannabis for pediatric epilepsy: protocol for a living systematic review. (Canada) (full – 2018) https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-018-0761-2
Evidence for THC versus CBD in cannabinoids. (Canada) (full – 2018) http://www.cfp.ca/content/64/7/519.long
Therapeutic Use of medicinal cannabis in difficult to manage epilepsy. (Australia) (full – 2018) https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.13711
Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor. (Spain) (full – 2018) https://molecularbrain.biomedcentral.com/articles/10.1186/s13041-018-0395-2
Potential Clinical Benefits of CBD-Rich Cannabis Extracts Over Purified CBD in Treatment-Resistant Epilepsy: Observational Data Meta-analysis. (Brazil) (full – 2018) https://www.frontiersin.org/articles/10.3389/fneur.2018.00759/full
Cannabidiol for Treatment of Childhood Epilepsy-A Cross-Sectional Survey. (Germany/ Spain) (full – 2018) https://www.frontiersin.org/articles/10.3389/fneur.2018.00731/full
Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age. (Brazil) (full – 2018) https://www.frontiersin.org/articles/10.3389/fimmu.2018.02009/full
The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus. (China) (full – 2018) https://www.sciencedirect.com/science/article/pii/S0920121118302201?via%3Dihub
Interaction between warfarin and cannabis. (Denmark) (full – 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/bcpt.13152
Efficacy of cannabinoids in paediatric epilepsy. (New Zealand/ Australia) (full – 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/dmcn.14087
A prospective open-label trial of a CBD/THC cannabis oil in dravet syndrome. (Canada) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144444/
Cannabis Therapeutics and the Future of Neurology. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200872/
Epilepsy and Cannabis: A Literature Review. (Pakistan/ USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235654/
Evidence for cannabis and cannabinoids for epilepsy: a systematic review of controlled and observational evidence. (Australia/ UK) (full – 2018) https://jnnp.bmj.com/content/89/7/741.long
Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome. (USA/ UK/ Spain) (full – 2018) https://www.nejm.org/doi/full/10.1056/NEJMoa1714631
Cannabis in palliative care: current challenges and practical recommendations. (Canada/ USA) (full – 2018) http://apm.amegroups.com/article/view/20097/21242
Erratum to cannabis in palliative care: current challenges and practical recommendations. (Canada/ USA) (erratum – 2018) http://apm.amegroups.com/article/view/23880/23545
Cannabidiol for Epilepsy: New Hope on the Horizon? (USA) (full – 2018) https://www.clinicaltherapeutics.com/article/S0149-2918(18)30325-4/fulltext
Schedules of Controlled Substances: Placement in Schedule V of Certain FDA-Approved Drugs Containing Cannabidiol; Corresponding Change to Permit Requirements. Final order. (USA) (full – 2018) https://www.federalregister.gov/documents/2018/09/28/2018-21121/schedules-of-controlled-substances-placement-in-schedule-v-of-
certain-fda-approved-drugs-containing Cannabis Oil in an Irish Children’s Critical Care Unit. (Ireland) (full – 2018) http://imj.ie/cannabis-oil-in-an-irish-childrens-critical-care-unit/
Treatment of infantile spasms. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293071/
Plants come to mind: phytocannabinoids, endocannabinoids and the control of seizures. (USA) (full – 2018) https://onlinelibrary.wiley.com/doi/full/10.1111/add.14540
Efficacy of CBD-enriched medical cannabis for treatment of refractory epilepsy in children and adolescents – An observational, longitudinal study. (Israel) (full – 2018) https://www.sciencedirect.com/science/article/pii/S0387760418301128
Simultaneous lipidomic and transcriptomic profiling in mouse brain punches of acute epileptic seizure model compared to controls. (Germany/ Netherlands) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794423/
Neuroprotective Action of the CB1/2 Receptor Agonist, WIN 55,212-2, against DMSO but Not Phenobarbital-Induced Neurotoxicity in Immature Rats. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318010/
Anticonvulsant and Neuroprotective Effects of Cannabidiol During the Juvenile Period. (USA) (full – 2018) https://academic.oup.com/jnen/article/77/10/904/5085875
Cannabis for the treatment of paediatric epilepsy? An update for Canadian paediatricians (Canada/ Israel) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234422/
Pharmacological characterization of the cannabinoid receptor 2 agonist, β-caryophyllene on seizure models in mice. (Brazil/ Bulgaria) (full – 2018) https://www.sciencedirect.com/science/article/pii/S1059131117306118
Coma, Seizures, Atrioventricular Block, and Hypoglycemia in an ADB-FUBINACA Body-Packer. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289710/
Cannabis and epilepsy. (UK/ Ireland) (full – 2018) https://pn.bmj.com/content/18/6/465.long
Prospects of Cannabidiol for Easing Status Epilepticus-Induced Epileptogenesis and Related Comorbidities. (USA/ India/ Brazil) (link to PDF – 2018) https://www.researchgate.net/publication/322709612_Prospects_of_Cannabidiol_for_Easing_Status_Epilepticus-Induced_Epileptogenesis_and_Related_Comorbidities
Cannabis for the Treatment of Epilepsy: an Update. (USA) (link to PDF – 2018) https://www.researchgate.net/publication/324263327_Cannabis_for_the_treatment_of_paediatric_epilepsy_An_update_for_Canadian_paediatricians
Practical considerations in medical cannabis administration and dosing. (Canada/ Czech Republic) (link to PDF – 2018) https://www.researchgate.net/publication/322257368_Practical_considerations_in_medical_cannabis_administration_and_dosing
Species-specific susceptibility to cannabis-induced convulsions. (UK/ Ireland/ USA) (download– 2018) Species-specific susceptibility to cannabis-induced convulsions The Path to the First FDA-Approved Cannabis-Derived Treatment and What Comes Next (USA) (link to download – article-2018) cha.com
Cannabinoids: just like any other medication? (UK) (article – 2018) https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31611-8/fulltext
Safety of cannabidiol prescribed for children with refractory epilepsy. (Italy) (letter – 2018) https://www.mja.com.au/journal/2018/209/5/safety-cannabidiol-prescribed-children-refractory-epilepsy
Cannabis, cannabis everywhere: UK to review medical cannabis policy as Canada plans imminent legalisation for all uses. (UK) st (1 page of editorial – 2018) https://www.bmj.com/content/361/bmj.k2695.long
Arvanil, olvanil, AM 1172 and LY 2183240 (various cannabinoid CB1 receptor agonists) increase the threshold for maximal electroshock-induced seizures in mice. (Poland) (abst – 2018) https://www.semanticscholar.org/paper/Arvanil%2C-olvanil%2C-AM-1172-and-LY-2183240-(various-Tutka-Wla%C5%BA/7a78fa93122b8296e83888c29e0ab5325d2fb6fd Medical cannabis: “restrictive” guidance lets patients down, say campaigners. (UK) (abst – 2018) https://www.bmj.com/content/363/bmj.k4654.full
Intoxication From Accidental Marijuana Ingestion in Pediatric Patients: What May Lie Ahead. (USA) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29406477
Control of excessive neural circuit excitability and prevention of epileptic seizures by endocannabinoid signaling. (Japan) (abst – 2018) https://link.springer.com/article/10.1007/s00018-018-2834-8
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Endocannabinoid CB1 receptors are involved in antiepileptogenic effect of low frequency electrical stimulation during perforant path kindling in rats. (Iran) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0920121117304291?via%3Dihub
Investigational cannabinoids in seizure disorders, what have we learned thus far? (Serbia) (abst – 2018) https://www.ncbi.nlm.nih.gov/pubmed/29842819
TRPV1 mediates the anticonvulsant effects of acetaminophen in mice. (Japan) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S0920121118300573
Efficacy and Safety of Adjunctive Cannabidiol in Patients with Lennox-Gastaut Syndrome: A Systematic Review and Meta-Analysis. (Italy) (abst – 2018) https://link.springer.com/article/10.1007%2Fs40263-018-0558-9
https://www.semanticscholar.org/paper/Efficacy-and-Safety-of-Adjunctive-Cannabidiol-in-A-Lattanzi-rigo/c4ea54cd471a6b7c849d581613b4abfb3c53dfd6
Genetic deletion of CB1 cannabinoid receptors exacerbates the Alzheimer-like symptoms in a transgenic animal model. (Spain) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303277
Cannabinoid signalling in the immature brain: Encephalopathies and neurodevelopmental disorders. (Spain/ Italy) (abst – 2018) https://www.sciencedirect.com/science/article/abs/pii/S0006295218303344
Inhibitions of anandamide transport and FAAH synthesis decrease apoptosis and oxidative stress through inhibition of TRPV1 channel in an in vitro seizure model. (Turkey) (abst – 2018) https://link.springer.com/article/10.1007/s11010-018-3439-0
https://www.semanticscholar.org/paper/Inhibitions-of-anandamide-transport-and-FAAH-and-of-Naz%C4%B1ro%C4%9Flu-Taner/fc43de120f4b6bce503fe59ae74b4f37be7c09e4 Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole- induced seizures in mice: Interaction between endogenous opioids and cannabinoids. (Iran/ Canada/ USA) (abst – 2018) https://www.epilepsybehavior.com/article/S1525-5050(17)30777-1/fulltext
Marijuana’s Effects on Brain Structure and Function: What Do We Know and What Should We Do? A Brief Review and Commentary. (USA) (abst – 2018) https://www.semanticscholar.org/paper/Efficacy-and-Safety-of-Cannabidiol-in-Epilepsy%3A-A-Lattanzi-Brigo/c429239f478174ae12a2cffdd6521f662d8d7662
Medical cannabis: A needs analysis for people with epilepsy. (Australia) (abst – 2018) https://www.sciencedirect.com/science/article/pii/S1744388118302354
The US Food and Drug Administration’s Authorization of the First Cannabis-Derived Pharmaceutical – Are We Out of the Haze? (USA) (abst – 2018) https://jamanetwork.com/journals/jamaneurology/article-abstract/2714720
The level of evidence of medical marijuana use for treating disabilities: a scoping review. (USA) (abst – 2018) https://www.tandfonline.com/doi/abs/10.1080/09638288.2018.1523952
Simultaneous quantification of thirteen cannabinoids and metabolites in human plasma by liquid chromatography tandem mass spectrometry in adult epilepsy patients. (USA) (abst – 2018) https://www.semanticscholar.org/paper/Simultaneous-Quantification-of-13-Cannabinoids-and-Roslawski-Remmel/bbfd94b9acff825e7108939c8fb28fa9e2905f43 Cannabis-based products for pediatric epilepsy: A systematic review. (Canada) (full – 2019) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.14608
The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain. (Czech Republic) (full – 2019) https://www.frontiersin.org/articles/10.3389/fpls.2018.01969/full
US Veterinarians’ Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338022/
Are there mortality risks for patients with epilepsy who use cannabis treatments as monotherapy? (USA) (full – 2019) https://www.sciencedirect.com/science/article/pii/S2213323218301567
Spontaneous, anecdotal, retrospective, open-label study on the efficacy, safety and tolerability of cannabis galenical preparation (Bedrocan). (Italy) (full – 2019) https://onlinelibrary.wiley.com/doi/full/10.1111/ijpp.12514
Epidiolex as adjunct therapy for treatment of refractory epilepsy: a comprehensive review with a focus on adverse effects. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396837/
Review of the many faces of synthetic cannabinoid toxicities. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398358/
Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations. (Canada) (full – 2019) https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-0990-z#Abs1
Medicinal use of cannabis based products and cannabinoids. (UK) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447998/

Single and Synergistic Effects of Cannabidiol and Δ-9-Tetrahydrocannabinol on Zebrafish Models of Neuro-Hyperactivity. (Canada) (full – 2019) https://www.frontiersin.org/articles/10.3389/fphar.2019.00226/full
Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials. (Italy) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514832/
Why I campaign for children like my son Alfie Dingley to be able to get medical cannabis. (UK) (full – 2019) https://www.bmj.com/content/365/bmj.l1921.long
Pharmacokinetics and Tolerability of Multiple Doses of Pharmaceutical-Grade Synthetic Cannabidiol in Pediatric Patients with Treatment-Resistant Epilepsy. (USA/ Belgium) (full – 2019) https://link.springer.com/article/10.1007%2Fs40263-019-00624-4
Synthetic, non-intoxicating 8,9-dihydrocannabidiol for the mitigation of seizures. (USA/ UK) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533278/
Metabolomics and Communication Skills Development in Children; Evidence from the Ages and Stages Questionnaire. (USA) (full – 2019) https://www.mdpi.com/2218-1989/9/3/42/htm
The safety, tolerability, and effectiveness of PTL-101, an oral cannabidiol formulation, in pediatric intractable epilepsy: A phase II, open-label, single-center study. (Israel) (full – 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30305-1/fulltext
Should more patients be offered treatment with cannabinoids? (Norway) (full – 2019) https://tidsskriftet.no/en/2019/09/kronikk/should-more-patients-be-offered-treatment-cannabinoids
Dravet Syndrome: An Overview. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713249/
Cannabidiol reduces seizures following CNS infection with Theiler’s murine encephalomyelitis virus. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698680/
Ontogeny and programming of the fetal temporal cortical endocannabinoid system by moderate maternal nutrient reduction in baboons (Papio spp.). (USA) (full – 2019) https://physoc.onlinelibrary.wiley.com/doi/full/10.14814/phy2.14024
Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions. (Australia) (full – 2019) https://onlinelibrary.wiley.com/doi/full/10.1111/epi.16355
American Epilepsy Society (AES): Written Comments to Norman E. “Ned” Sharpless, MD, Acting Commissioner of Food and Drugs, U.S. Food and Drug Administration (FDA), Department of Health and Human Services (HHS): on Docket ID# FDA-2019-N- 1482, Scientific Data and Information about Products Containing Cannabis or Cannabis- Derived Compounds; Public Hearing; Request for Comments: Submitted on: July 16, 2019. (USA) (full – 2019) https://journals.sagepub.com/doi/full/10.1177/1535759719878716?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed Cannabidiol. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK548890/

A preliminary study of the effects of cannabidiol (CBD) on brain structure in patients with epilepsy. (USA) (full – 2019) https://www.sciencedirect.com/science/article/pii/S258998641930111X
The Interplay between the Endocannabinoid System, Epilepsy and Cannabinoids. (Australia) (full – 2019) https://www.mdpi.com/1422-0067/20/23/6079/htm
Effects of CBD-Enriched Cannabis sativa Extract on Autism Spectrum Disorder Symptoms: An Observational Study of 18 Participants Undergoing Compassionate Use. (Brazil) (full – 2019) https://www.frontiersin.org/articles/10.3389/fneur.2019.01145/full
Cannabidiol attenuates seizures and EEG abnormalities in Angelman syndrome model mice. (USA) (full – 2019) https://www.jci.org/articles/view/130419
Cannabis-based medicinal products. (UK) (full – 2019) https://www.ncbi.nlm.nih.gov/books/NBK552187/
Cannabis Influences the Putative Cytokines-Related Pathway of Epilepsy among Egyptian Epileptic Patients. (Egypt/ Germany) (link to PDF – 2019) https://www.mdpi.com/2076-3425/9/12/332
Investigating the Therapeutic Mechanism of Cannabidiol in a Human Induced Pluripotent Stem Cell (iPSC)-Based Cellular Model of Dravet Syndrome. (USA) (download – 2019) http://symposium.cshlp.org/content/early/2019/06/11/sqb.2018.83.038174.long
Crossing the Line: Care of a Pediatric Patient with Intractable Seizures and Severe Neuropathic Pain in Absence of Access to Medical Marijuana. (USA) (link to download – 2019) https://www.cedfoundation.com/wp-content/uploads/2019/06/Crossing-the-Line-Care-of-a-Pediatric-Patient-with-Intractable-Seizures-and-Severe-Neuropathic-Pain-in-Absence-of-Access-to-Medical-Marijuana.pdf
Why medical cannabis is still out of patients’ reach-an essay by David Nutt. (UK) (click “drugscience” for download – 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=Why+medical+cannabis+is+still+out+of+patients%27+reach
-an+essay+by+David+Nutt.&btnG
Cannabis-based treatments as an alternative remedy for epilepsy. (USA) (article – 2019) https://www.sciencedirect.com/science/article/pii/S221342201930157X

Medical cannabis: no NHS patients have benefited from law change, say campaigners (UK) (1st page – 2019) https://www.bmj.com/content/364/bmj.l753
The Surprising Reach of FDA Regulation of Cannabis, Even After Descheduling (USA) (abst–2019) https://www.ncbi.nlm.nih.gov/pubmed/30919712
Cannabidiol: A New Hope for Patients With Dravet or Lennox-Gastaut Syndromes. (USA) (abst–2019) https://www.ncbi.nlm.nih.gov/pubmed/30616356
Cannabinoid therapy in epilepsy. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30676535
A Review of Human Studies Assessing Cannabidiol’s (CBD) Therapeutic Actions and Potential. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30730563
Cannabis for refractory epilepsy in children: A review focusing on CDKL5 Deficiency Disorder. (Australia/ USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0920121118306107
Improving post-hypoxic myoclonus using cannabidiol. (USA) (abst – 2019) https://www.seizure-journal.com/article/S1059-1311(18)30573-9/fulltext
Reclassifying cannabis based drugs has not made accessing them easier, MPs hear. (UK) (abst – 2019) https://www.bmj.com/content/364/bmj.l1302.long
Safety, efficacy, and mechanisms of action of cannabinoids in neurological disorders. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30910443
Cannabidiol as adjunctive treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome. (Italy/ Austria) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30938373
Disposition of oral delta-9 tetrahydrocannabinol (THC) in children receiving cannabis extracts for epilepsy. (USA) (abst – 2019) https://www.tandfonline.com/doi/abs/10.1080/15563650.2019.1616093?journalCode=ictx20
Medical Marijuana in the Pediatric Population With Epilepsy-What You Should Know. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31160106
Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy. (USA) (abst – 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.16093
Marijuana use among patients with epilepsy at a tertiary care center. (USA) (abst – 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30222-7/fulltext
Pharmacological and Therapeutic Properties of Cannabidiol for Epilepsy. (Italy) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31372958
Knowledge, expectations and fears of cannabis use of epilepsy patients at a tertiary epilepsy center. (Germany) (abst – 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30538-4/fulltext
Drug–drug interactions and pharmacodynamics of concomitant clobazam and cannabidiol or stiripentol in refractory seizures. (USA) (abst – 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30449-4/fulltext
Early endocannabinoid system activation attenuates behavioral impairments induced by initial impact but does not prevent epileptogenesis in lithium–pilocarpine status epilepticus model. (Russia) (abst – 2019) https://www.epilepsybehavior.com/article/S1525-5050(18)30727-3/fulltext
Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0968089619310235?via%3Dihub
Clinical trial simulations of the interaction between cannabidiol and clobazam and effect on drop-seizure frequency. (Netherlands) (abst – 2019) https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.14158
Cannabinoids, hippocampal excitability and efficacy for the treatment of epilepsy. (Israel) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0163725819301093
Marijuana use among patients with epilepsy at a tertiary care center. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S1525505019302227
Pharmacokinetics of Phytocannabinoid Acids and Anticonvulsant Effect of Cannabidiolic Acid in a Mouse Model of Dravet Syndrome. (Australia) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31686510
Cannabidiol: Recent advances and new insights for neuropsychiatric disorders treatment. (Italy/ Sweden) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0024320519302176
Medicinal cannabis in Latin America: History, current state of regulation, and the role of the pharmacist in a new clinical experience with cannabidiol oil. (Argentina) (abst–2019) https://www.sciencedirect.com/science/article/abs/pii/S1544319119304285
Cannabidiol: A Review of Clinical Efficacy and Safety in Epilepsy. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0887899418311688
Efficacy and adverse event profile of cannabidiol and medicinal cannabis for treatment- resistant epilepsy: Systematic review and meta-analysis. (Brazil) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31731110
Safety, efficacy, and mechanisms of action of cannabinoids in neurological disorders (USA/ Italy) (abst–2019) https://www.sciencedirect.com/science/article/abs/pii/S1474442219300328
Epileptic Spikes in EEG and Migraine Attacks in the Course of Cannabis Withdrawal: A Case Report. (Germany) (abst – 2019) https://journals.sagepub.com/doi/abs/10.1177/1550059419886704?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=eegb
Reduced cannabinoid 2 receptor activity increases susceptibility to induced seizures in mice. (USA) (abst – 2019) https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.16388
Cannabinoids for drug-resistant seizures in a critically ill patient-Case report and literature review. (Australia) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31770462
The use of medical grade cannabis in Italy for drug-resistant epilepsy: a case series. (Italy) (abst – 2019) https://link.springer.com/article/10.1007/s10072-019-04162-1
A perspective on cannabinoids for treating epilepsy: do they really change the landscape? (UK) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0028390819304277?via%3Dihub
Synthetic pharmaceutical grade cannabidiol for treatment of refractory infantile spasms: A multicenter phase-2 study. (USA/ Belgium) (abst – 2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30916-3/fulltext
Cannabis-based medicines and the perioperative physician. (Canada/ UK) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31827774
Cannabinoids and the expanded endocannabinoid system in neurological disorders. (Italy/ Canada) (abst – 2019) https://www.nature.com/articles/s41582-019-0284-z
Exploiting cannabinoid and vanilloid mechanisms for epilepsy treatment. (Brazil) (abst–2019) https://www.epilepsybehavior.com/article/S1525-5050(19)30373-7/fulltext
Potential role of cannabidiol for seizure control in a patient with recurrent glioma (Australia) (abst – 2019) https://www.jocn-journal.com/article/S0967-5868(19)31306-2/fulltext

The cannabidiol conundrum potential benefits and risks of cannabidiol products for children. (USA) (abst – 2019) https://journals.lww.com/co-pediatrics/Abstract/publishahead/The_cannabidiol_conundrum__potential_benefits_and.98783.aspx
Synthetic cannabinoid receptor agonists-induced recurrent seizure in elderly patient. (USA) (abst – 2019) https://www.ajemjournal.com/article/S0735-6757(19)30752-1/fulltext
Phytocannabinoids in Neurological Diseases: Could They Restore a Physiological GABAergic Transmission? (Italy/ Netherlands) (full – 2020) https://www.mdpi.com/1422-0067/21/3/723/htm
Medical Cannabis for Intractable Epilepsy in Childhood: A Review. (Israel) (link to download – 2020) https://www.rmmj.org.il/userimages/1024/1/PublishFiles/1029Article.pdf
Medical Cannabis in Children. (Israel) (link to download – 2020) https://www.rmmj.org.il/userimages/1010/1/PublishFiles/1026Article.pdf
Cannabis-based products for pediatric epilepsy: An updated systematic review. (Canada) (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31865133
The Use of Cannabis as a Treatment for Epilepsy in Adult Patients: Are Side Effects a Limitation of Use? (Canada/ Colombia) (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31895185
The Endocannabinoid System and Synthetic Cannabinoids in Preclinical Models of Seizure and Epilepsy. (Canada) (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31895186
A North American History of Cannabis Use in the Treatment of Epilepsy (Canada) (abst–2020) https://www.ncbi.nlm.nih.gov/pubmed/31895188
Cannabis for Pediatric Epilepsy. (Canada/ USA) (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31895184
The cannabidiol conundrum: potential benefits and risks of cannabidiol products for children. (USA) (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31833952
The role of cannabinoids in epilepsy treatment: a critical review of efficacy results from clinical trials. (France/ USA) (abst – 2020) https://www.ncbi.nlm.nih.gov/pubmed/31916540
The anticonvulsant effects of cannabidiol in experimental models of epileptic seizures: From behavior and mechanisms to clinical insights. (Brazil) (abst – 2020) https://www.sciencedirect.com/science/article/abs/pii/S014976341931067X
The other side of the leaf: Seizures associated with synthetic cannabinoid use. (Australia) (abst – 2020) https://www.epilepsybehavior.com/article/S1525-5050(19)31190-4/fulltext


ESSENTIAL TREMOR
Cannabinoid type 1 receptor antagonism ameliorates harmaline-induced essential tremor in rat. (Iran/ UK) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071561/
Cannabinoid receptor agonism suppresses tremor, cognition disturbances and anxiety-like behaviors in a rat model of essential tremor. (Iran/ UK) (click “readingacuk” for download – 2016) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Cannabinoid+receptor+agonism+suppresses+tremor%2C+cognition+disturbances+and+anxiety-like+behaviors+in+a+rat+model+of+essential+tremor%22&btnG
Effect of marijuana on Essential Tremor: A case report. (USA) (abst – 2016) http://www.mdsabstracts.org/abstract/effect-of-marijuana-on-essential-tremor-a-case-report/


ETHICS and CANNABIS
Bioethical analysis to the therapeutic use of Cannabis: Integrative review. (Brazil) (abst – 2017) https://www.semanticscholar.org/paper/Bioethical-analysis-to-the-therapeutic-use-of-Vasconcelos-
Silva/ad2d2a17b489a983063db23cd856a3d5ea1f5ccb Ethical Issues Arising from Marijuana Use by Nursing Mothers in a Changing Legal and Cultural Context. (USA) (abst – 2018) https://link.springer.com/article/10.1007%2Fs10730-018-9368-1
Ethical issues in medical cannabis use. (Israel) (abst – 2018) https://www.ejinme.com/article/S0953-6205(18)30016-5/fulltext
Cannabis money opens new opportunities, and ethical dilemmas, for medical research. (Canada) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379174/
Cannabis for Inflammatory Bowel Diseases: Should We Follow the Wisdom of the Crowd? (Israel) (full – 2019) https://www.ima.org.il/MedicineIMAJ/viewarticle.aspx?year=2019&month=11&page=756
Ethical Implications for Providers Regarding Cannabis Use in Children With Autism Spectrum Disorders. (USA) (click “aappublicationsorg” for full – 2019) https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=%22Ethical+Implications+for+Providers+Regarding+Cannabis+Use+in+Children+With+Autism+Spectrum+Disorders.%22&btnG


EXERCISE and the ENDOCANNABINOID SYSTEM*+
A runner’s high depends on cannabinoid receptors in mice. (Germany) (full – 2015) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620874/
Cannabinoid Receptor 1 and Acute Resistance Exercise – In vivo and In vitro Studies in Human Skeletal Muscle. (Finland/ France/ China) (abst – 2015) http://www.sciencedirect.com/science/article/pii/S0196978
115000650 https://www.semanticscholar.org/paper/Cannabinoid-receptor-1-and-acute-resistance-vivo-in-Pekkala-Wiklund/3259bffc58c7e9e1d264996e9102e9f0957efe1f Deletion of G-protein coupled receptor 55 promotes obesity by reducing physical activity. (USA/ China) (abst – 2015) https://www.semanticscholar.org/paper/Deletion-of-G-protein-coupled-receptor-55-promotes-Meadows-Lee/a372db59bc393f54339d909f71aff73fd0e75f51
Cannabis and Exercise Science: A Commentary on Existing Studies and Suggestions for Future Directions (USA) (abst–2015) http://link.springer.com/article/10.1007/s40279-015-0362-3
Changes in IGF-I, urinary free cortisol and adipokines during dronabinol therapy in anorexia nervosa: Results from a randomised, controlled trial. (Denmark) (abst – 2015) https://www.sciencedirect.com/science/article/abs/pii/S1096637415300174
Neuromodulation of Aerobic Exercise—A Review (Netherlands/ Germany) (full–2016) http://journal.frontiersin.org/article/10.3389/fpsyg.2015.01890/full
Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans. (Sweden/ Italy/ Germany) (full – 2016) https://www.sciencedirect.com/science/article/pii/S0306453016307156
Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. (USA/ China) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082783/
Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes. (USA) (full – 2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305303/
Restricted vs. unrestricted wheel running in mice: Effects on brain, behavior and endocannabinoids. (Germany) (link to PDF – 2016) https://www.researchgate.net/publication/308385940_Restricted_vs_unrestricted_wheel_running_in_mice_Effects_on_brain_behavior_and_endocannabinoids
Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity. (France/ Italy) (abst – 2016) https://link.springer.com/article/10.1007%2Fs13105-016-0469-5
https://www.semanticscholar.org/paper/Effects-of-chronic-exercise-on-the-endocannabinoid-Gamelin-Aucouturier/6a3353c8618ca8bf69574c455f19206be6db17a2
Exercise deprivation increases negative mood in exercise-addicted subjects and modifies their biochemical markers. (Brazil) (abst – 2016) https://www.sciencedirect.com/science/article/abs/pii/S0031938416300269
The role of exercise training and the endocannabinoid system in atherosclerotic plaque burden and composition in Apo-E-deficient mice. (Greece) (full – 2017) http://www.sciencedirect.com/science/article/pii/S1109966616302949

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Anxious behavior induces elevated hippocampal Cb2 Receptor gene expression. (USA) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482502/
Running Out of Options: Rhabdomyolysis Associated with Cannabis Hyperemesis Syndrome (USA) (full–2017) https://link.springer.com/article/10.1007%2Fs11606-017-4111-1
Cannabinoid CB1/CB2 receptor agonists attenuate hyperactivity and body weight loss in a rat model of activity-based anorexia. (Italy) (full – 2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522993/
Circulating Endocannabinoids: From Whence Do They Come and Where are They Going? (USA) (full – 2017) https://www.nature.com/articles/npp2017130
Exercise versus targeting of endocannabinoid system for atheromatic plaque stabilization. Opposing or complementary roles? (Greece) (link to PDF – 2017) https://www.researchgate.net/publication/316356545_Exercise_versus_targeting_of_endocannabinoid_system_for_atheromatic_plaque_stabilization_Opposing_or_complementary_roles
Anti-migraine effect of ∆9-tetrahydrocannabinol in the female rat. (USA) (link to PDF–2017) https://www.researchgate.net/publication/320687020_Anti-migraine_effect_of_9_-tetrahydrocannabinol_in_the_female_rat
Endocannabinoid and Opioid System Interactions in Exercise-Induced Hypoalgesia. (USA) (link to PDF – 2017) https://www.researchgate.net/publication/315804249_Endocannabinoid_and_Opioid_System_Interactions_in_Exercise-Induced_Hypoalgesia
Psychobiological Responses to Aerobic Exercise in Individuals With Posttraumatic Stress Disorder. (USA) (link to PDF– 2017) https://www.researchgate.net/publication/322878985_Psychobiological_Responses_to_Aerobic_Exercise_in_Individuals_With_Posttraumatic_Stress_Disorder_Psychobiological_Responses_to_Exercise_in_PTSD
Endocannabinoid and Mood Responses to Exercise in Adults with Varying Activity Levels. (USA) (link to PDF – 2017) https://www.researchgate.net/publication/315436386_Endocannabinoid_and_Mood_Responses_to_Exercise_in_Adults_with_Varying_Activity_Levels
Cannabis: Exercise performance and sport. A systematic review. (Australia) (link to PDF – 2017) https://www.researchgate.net/publication/315508827_Cannabis_Exercise_performance_and_sport_A_systematic_review
Exercise training and high-fat diet elicit endocannabinoid system modifications in the rat hypothalamus and hippocampus. (France/ Italy) (link to PDF – 2017) https://www.researchgate.net/publication/314654573_Exercise_training_and_high-
fat_diet_elicit_endocannabinoid_system_modifications_in_the_rat_hypothalamus_and_hippocampus Voluntary exercise improves cognitive deficits in female dominant-negative DISC1 transgenic mouse model of neuropsychiatric disorders. (Israel) (click “Alternate Sources” then “46cec243-71bb-” for download – 2017) https://www.semanticscholar.org/paper/Voluntary-exercise-improves-cognitive-deficits-in-Segal-Gavish-Barzilay/e9adb9bebe91894f3580738910184f418ad710f8
AMPK contributes to aerobic exercise-induced antinociception downstream of endocannabinoids. (Germany) (abst – 2017) http://www.sciencedirect.com/science/article/pii/S0028390817301983
https://www.semanticscholar.org/paper/AMPK-contributes-to-aerobic-exercise-induced-of-King-Himmelreich-M%C3%B6ser/38d3032bd17c54f9e2d406857e9c577dd07262c9
Moderate and vigorous physical activity patterns among marijuana users: Results from the 2007-2014 National Health and Nutrition Examination Surveys. (USA) (abst – 2017) https://www.sciencedirect.com/science/article/abs/pii/S0376871617302752
https://www.semanticscholar.org/paper/Moderate-and-vigorous-physical-activity-patterns-Vidot-Bispo/0fcf7f31c5b3aa51cc72d57052ad4a450a1f15e3
The Use of Complementary and Alternative Medicine in Patients With Inflammatory Bowel Disease. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111500/
Effects of exercise on experimentally manipulated craving for cannabis: A preliminary study. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162100/
A Behavioral Economic Analysis of Marijuana and Other Drug Use Among Heavy Drinking Young Adults. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005693/
Aerobic Fitness Level Moderates the Association Between Cannabis Use and Executive Functioning and Psychomotor Speed Following Abstinence in Adolescents and Young Adults. (USA) (full – 2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374167/
Endocannabinoids, exercise, pain, and a path to health with aging. (USA) (full – 2018) https://www.researchgate.net/publication/328114934_Endocannabinoids_exercise_pain_and_a_path_to_health_with_aging
Endogenous systems involved in exercise-induced analgesia. (Brazil) (full – 2018) http://www.jpp.krakow.pl/journal/archive/02_18/articles/01_article.html
Seasonal Changes in Endocannabinoid Concentrations between Active and Hibernating Marmots (Marmota flaviventris). (USA) (full – 2018) https://journals.sagepub.com/doi/full/10.1177/0748730418777660?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org Effect of Vaporized Cannabis on Exertional Breathlessness and Exercise Endurance in Advanced COPD: A Randomized Controlled Trial. (Canada) (full– 2018) https://www.atsjournals.org/doi/10.1513/AnnalsATS.201803-198OC
The New Runner’s High? Examining Relationships Between Cannabis Use and Exercise Behavior in States With Legalized Cannabis. (USA) (full – 2019) https://www.frontiersin.org/articles/10.3389/fpubh.2019.00099/full
The Endocannabinoid System as a Potential Mechanism through which Exercise Influences Episodic Memory Function. (China/ USA) (full – 2019) https://www.mdpi.com/2076-3425/9/5/112/htm
The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors. (France/ Spain/ Italy) (full – 2019) https://insight.jci.org/articles/view/126190
Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome. (Canada/ Italy) (full – 2019) https://www.mdpi.com/2072-6643/11/8/1956/htm
Beyond the Activity-Based Anorexia Model: Reinforcing Values of Exercise and Feeding Examined in Stressed Adolescent Male and Female Mice. (France) (full – 2019) https://www.frontiersin.org/articles/10.3389/fphar.2019.00587/full
An Analysis of Endocannabinoid Concentrations and Mood Following Singing and Exercise in Healthy Volunteers. (UK) (full – 2019) https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00269/full
Chronic exercise modulates the cellular immunity and its cannabinoid receptors expression. (Mexico) (full – 2019) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220542
Serum Endocannabinoid and Mood Changes after Exercise in Major Depressive Disorder. (USA) (full – 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727944/
[EXPRESS] Altered relationship between anandamide and glutamate in circulation after 30 minutes of arm cycling: A comparison of chronic pain subject with healthy controls. (Sweden) (link to PDF – 2019) https://journals.sagepub.com/doi/abs/10.1177/1744806919898360
Loss of exercise- and stress-induced increases in circulating 2-arachidonoylglycerol concentrations in adults with chronic PTSD. (USA) (link to download – 2019) Loss of exercise- and stress-induced increases in circulating 2 … Is Cannabis Use Associated with Sedentary Behavior during Leisure Time? A Study in Canada, 2011-2012. (Canada) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/30658548
Performance and Health-Related Characteristics of Physically Active Males Using Marijuana. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/29023325
Diet, endocannabinoids, and health. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S027153171930572X?via%3Dihub
Chronic aerobic exercise: Lack of effect on brain CB1 receptor levels in adult rats. (USA) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S002432051930414X?via%3Dihub
Cannabis use and leisure-time sedentary behavior among 94,035 adolescents aged 12– 15 years from 24 low- and middle-income countries. (Belgium/ Australia/ UK/ Canada/ Spain) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0306460319305349?via%3Dihub
Involvement of Spinal Cannabinoid CB2 Receptors in Exercise-Induced Antinociception. (Brazil) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0306452219306165
Low intensity blood flow restriction exercise: Rationale for a hypoalgesia effect. (UK) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0306987719307364
Antinociceptive effects of treadmill exercise in a rat model of Parkinson’s disease: the role of cannabinoid and opioid receptors. (Brazil) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S000689931930575X?via%3Dihub
Cannabis use and physical activity among 89,777 adolescents aged 12-15 years from 21 low- and middle-income countries. (Canada/ UK/ Belgium/ Australia/ Italy/ Spain) (abst – 2019) https://www.sciencedirect.com/science/article/abs/pii/S0376871619303618?via%3Dihub
Psychological and endocannabinoid responses to aerobic exercise in substance use disorder patients. (USA) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31729933
Anandamide Is Related to Clinical and Cardiorespiratory Benefits of Aerobic Exercise Training in Migraine Patients: A Randomized Controlled Clinical Trial. (Brazil) (abst – 2019) https://www.ncbi.nlm.nih.gov/pubmed/31872062
Treadmill exercise improves LPS-induced memory impairments via endocannabinoid receptors and cyclooxygenase enzymes. (Iran) (abst – 2019) https://www.sciencedirect.com/science/article/pii/S0166432819310435?via%3Dihub 

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Updated 20 March 2020